Collagen HydraPlump With Ceramides Ingredients & Drug Interactions
by ResVitale
What is this page for?
First and foremost: checking Collagen HydraPlump With Ceramides against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Collagen HydraPlump With Ceramides is a dietary supplement by ResVitale with 4 active ingredients. Its ingredients are commonly taken for osteoarthritis joint pain, joint stiffness, cartilage support.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chondroitin Sulfate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Collagen HydraPlump With Ceramides by ResVitale
Ask about any prescription or over-the-counter medication and we check it for interactions with Collagen HydraPlump With Ceramides by ResVitale — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Collagen HydraPlump With Ceramides by ResVitale
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product has 4 active ingredients. Chondroitin sulfate and hydrolyzed collagen type II are structural components — chondroitin supports joint cartilage, and collagen provides protein that may help skin elasticity and firmness.
Hyaluronic acid is a natural substance that holds water in skin and may help with hydration. Ceramosides (a wheat extract) completes the blend.
The capsule also contains rice bran and silica as inactive ingredients.
Does it work?
Moderate evidence
The evidence is mixed. Hydrolyzed collagen type II shows the strongest data: it's possibly effective for aging skin and dry skin.
Chondroitin sulfate is possibly effective for cataracts and osteoarthritis, though the quality and benefit are uncertain. Hyaluronic acid is possibly effective for dry eyes and leg ulcers.
For the main skin-aging claim here, the data on chondroitin and hyaluronic acid isn't established — they're rated insufficient evidence. We hold no effectiveness data for ceramosides.
How safe is it?
Well-documented data
Chondroitin sulfate is generally well tolerated for short-term use, but the data isn't strong enough for long-term safety. The most common side effects are digestive: abdominal pain, bloating, constipation, diarrhea, heartburn, and nausea.
Rare serious effects include liver damage. Skin symptoms like eyelid puffiness, rash, and hives have been reported, especially in combination products.
Hyaluronic acid is well tolerated orally, though long-term supplement safety hasn't been fully studied. Hydrolyzed collagen is generally well tolerated; nausea, indigestion, diarrhea, and gas are rare.
Pregnancy and breastfeeding: the safety data advises against chondroitin in pregnancy and lactation. For hydrolyzed collagen and hyaluronic acid, there isn't enough data — talk with your doctor or pharmacist for personalized advice.
We hold no pregnancy or breastfeeding data for ceramosides.
Meds to double-check
Moderate interaction found
If you take warfarin (Coumadin) or another blood thinner, double-check this product before starting — chondroitin sulfate may increase its blood-thinning effect. No other medication interactions are documented for the ingredients we could check.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product may be worth considering if you're interested in skin hydration and joint support, but the skin-aging claims aren't backed by strong evidence. If you take warfarin or any blood thinner, check with us or your pharmacist first — chondroitin may interact.
Pregnant or breastfeeding? Talk with your doctor before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2014.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Collagen HydraPlump With Ceramides, straight from the product label.
| Brand | ResVitale |
|---|---|
| Net contents | 30 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Apr 25, 2014 |
| DSLD ID | 31983 |
| Product type | Botanical With Nutrients |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Collagen HydraPlump With Ceramides by ResVitale, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Chondroitin Sulfate | 100 mg | -- |
| Hyaluronic Acid | 50 mg | -- |
| Hydrolyzed Collagen Type II | 300 mg | -- |
| BioCell Collagen | 500 mg | -- |
| Ceramosides(TM) Ceramide Wheat Extract | 15 mg | -- |
Other ingredients: Capsule, Rice Bran, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Clinical support shows this ingredient may help restore skin’s vulnerable moisture barrier beginning in as little as 2 weeks.
NEW RESULTS IN AS LITTLE AS 2 WEEKS
Restores skin’s moisture barrier beginning in as little as 2 weeks Helps replenish protective Ceramide lipids
THE ART Drawing from our longstanding expertise in skincare supplement science, ResVitale unveils a groundbreaking collection of collagen formulas featuring types I, II and III. Our collagen sources independently receive industry accolades for quality. In the way only ResVitale can, we pair them with complementary youth-activating ingredients for unparalleled results.
THE BENEFITS When depleting collagen stores are replenished, the effects can be remarkable and visible. Skin feels softer and smoother to the touch. The appearance of lines fades and diminishes to complement your daily skincare regimen.
THE PROOF Scientific evidence of our independent collagen sources reveal astounding results including, smoothing the appearance of facial lines and improved resiliency to skin’s collagen mesh.
Renew skin’s suppleness. Undo aging and environmental aggression. This prohydration maintenance complex boosts skin’s ability to do both. Ceramides lock in moisture at skin’s surface and retain hydration. Depleted levels contribute to a dull, lifeless appearance.
Formula
BioCell Collagen(R) with naturally occurring Hyaluronic Acid delivers a plumping effect.
Contains wheat.
Brand IP Statement(s)
ADVANCED SKINCARE FROM WITHIN(TM)
Boosts fullness with dual-action BioCell Collagen(R)
BioCell Collagen(R) is a registered trademark of BioCell Technology, LLC Newport Beach California, USA (US Patent Pending 6,025,327; 6,323,319; 7,780,841; 7,091,180; 7,799,348 other US and foreign patents pending). Ceramosides(TM) is the trademark of E.P.I. France.
About Collagen HydraPlump(TM)
Ceramosides(TM) Ceramides infuse skin with moisture-locking lipids that bump up hydration for skin that’s softer and smoother.
Seals/Symbols
THE SCIENCE OF BEAUTY
BioCell Collagen(R)
FDA Statement of Identity
DIETARY SUPPLEMENT
Precautions
Contains wheat.
Infants, children, pregnant or breast feeding women should avoid using this product. Please check with your doctor before using this product if you are under a doctor’s care or are taking medication.
Infants, children, pregnant or breast feeding women should avoid using this product.
KEEP OUT OF REACH OF CHILDREN AND PETS.
Formulation
Does not contain: Soy, yeast, lactose, citrus, milk, egg or fish products, sugar, salt, starch, artificial coloring or flavoring, or preservatives. Gluten free.
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, take 1 capsule twice daily or as recommended by your healthcare practitioner.
Storage
Store tightly in a cool, dry place.
General
VC1681 VA1680
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Collagen HydraPlump With Ceramides by ResVitale label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Collagen HydraPlump With Ceramides by ResVitale
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
BioCell Collagen
Ceramosides(TM) Ceramide Wheat Extract
Other (inactive) ingredients: Capsule, Rice Bran, Silica. These complete the product’s ingredient list but are not active constituents.
Collagen HydraPlump With Ceramides by ResVitale Drug Interactions
HelloPharmacist Interaction Report
ResVitale's Collagen HydraPlump With Ceramides contains one ingredient with documented drug interactions: chondroitin sulfate.
The main concern is with warfarin (a blood thinner used to prevent clots). When chondroitin is combined with glucosamine, it may increase warfarin's blood-thinning effects, raising your clotting time (INR).
The effect of chondroitin alone is less clear, but if you take warfarin, you'll want to check this product before starting.
Read the full breakdown — every affected drug type, severity by severity
Additionally, hyaluronic acid and hydrolyzed collagen type II have no known interactions documented in our data.
We couldn't check ceramosides (the wheat extract form) — we hold no interaction data for it. Altogether, these interactions span 2 individual medications.
Use the medication checker on this page to verify your exact drugs before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Collagen HydraPlump With Ceramides?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Collagen HydraPlump With Ceramides interact with 2 drugs. Click any drug to see the details.
1 of the 4 ingredients in Collagen HydraPlump With Ceramides interact with drugs. Each result below shows which ingredient is responsible. Chondroitin Sulfate
WarfarinWarfarin
How Warfarin interacts with Collagen HydraPlump With Ceramides — through 1 ingredient. Tap an ingredient for the detail:
Chondroitin SulfateWarfarin (coumadin) Moderate
Interaction Summary
Taking chondroitin in combination with glucosamine might increase the anticoagulant effects of warfarin.
Read the full Chondroitin Sulfate + Warfarin interactionWarfarin SodiumCoumadin, Panwarfin, Sofarin
How Warfarin Sodium interacts with Collagen HydraPlump With Ceramides — through 1 ingredient. Tap an ingredient for the detail:
Chondroitin SulfateWarfarin (coumadin) Moderate
Interaction Summary
Taking chondroitin in combination with glucosamine might increase the anticoagulant effects of warfarin.
Read the full Chondroitin Sulfate + Warfarin Sodium interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Collagen HydraPlump With Ceramides with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Chondroitin Sulfate
Warfarin (Coumadin)
Taking chondroitin in combination with glucosamine might increase the anticoagulant effects of warfarin. However, the effect of chondroitin alone is unclear.
There have been multiple reports of increased international normalized ratio (INR) in patients taking warfarin with glucosamine, with or without chondroitin. The lack of reports with chondroitin alone seem to suggest that the interactions occurring in these reports may have been due to glucosamine. In two individual case reports, glucosamine/chondroitin combinations were associated with a significant increase in INR in patients previously stabilized on warfarin. Additionally, 20 voluntary case reports to the US Food & Drug Administration (FDA) have linked glucosamine plus chondroitin with increased INR, bruising, and bleeding in patients who were also taking warfarin. There have also been 20 additional case reports to the World Health Organization (WHO) that link glucosamine alone, without chondroitin, to increased INR in patients taking warfarin.
Brand information
Manufacturer and brand details for Collagen HydraPlump With Ceramides, from the product label.
ResVitale
See all ResVitale products- Name
- RESVITALE
- Street Address
- 701 S. Howard Ave., Suite 106-310
- City
- Tampa
- State
- FL
- ZipCode
- 33606
- Phone Number
- 1-877-787-5454
- Web Address
- www.resvitale.com
Collagen HydraPlump With Ceramides by ResVitale: Common Questions
Does Collagen HydraPlump With Ceramides by ResVitale interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does this help with wrinkles and aging skin?
What are the most common side effects?
Is it safe during pregnancy?
Can I take this while breastfeeding?
What is hyaluronic acid doing in a skin product?
I take warfarin for my heart. Is this safe?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Collagen HydraPlump With Ceramides is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Collagen HydraPlump With Ceramides’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Chondroitin Sulfate
Interacts with 2 drugsChondroitin sulfate is a naturally occurring building block of cartilage that is widely taken, often with glucosamine, for osteoarthritis joint pain. The evidence is mixed—some people report...
Read the full Chondroitin Sulfate monograph → Herb & supplement monographHyaluronic Acid
Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin moisture and joint comfort, and the evi...
Read the full Hyaluronic Acid monograph → Herb & supplement monographCollagen Peptides
Collagen peptides are a well-absorbed form of protein that may modestly improve skin elasticity and joint comfort for some people, though evidence is still developing and results vary. They...
Read the full Collagen Peptides monograph →Sources & How We Checked
Collagen HydraPlump With Ceramides's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 28 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Chondroitin Sulfate 22 references
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
- Tallia AF, Cardone DA. Asthma exacerbation associated with glucosamine-chondroitin supplement. J Am Board Fam Pract 2002;15:481-4..
- Danao-Camara T. Potential side effects of treatment with glucosamine and chondroitin. Arthritis Rheum 2000;43:2853. PubMed
- Rozenfeld V, Crain JL, Callahan AK. Possible augmentation of warfarin effect by glucosamine-chondroitin. Am J Health Syst Pharm 2004;61:306-307. PubMed
- Clegg DO, Reda DJ, Harris CL, et al. Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis. N Engl J Med 2006;354:795-808. DOI
- Knudsen J, Sokol GH. Potential glucosamine-warfarin interaction resulting in increased international normalized ratio: Case report and review of the literature and MedWatch database. Pharmacotherapy 2008;28:540-8. PubMed
- Yue QY, Strandell J, Myrberg O. Concomitant use of glucosamine potentiates the effect of warfarin. Jan 2006. Drug Safety 29(10):911-1010. DOI
- Nordling, J. and van, Ophoven A. Intravesical glycosaminoglycan replenishment with chondroitin sulphate in chronic forms of cystitis. A multi-national, multi-centre, prospective observational clinical trial. Arzneimittelforschung. 2008;58(7):328-335. PubMed
- Nickel, J. C., Egerdie, B., Downey, J., Singh, R., Skehan, A., Carr, L., and Irvine-Bird, K. A real-life multicentre clinical practice study to evaluate the efficacy and safety of intravesical chondroitin sulphate for the treatment of interstitial cystit
- Oliviero, U., Sorrentino, G. P., De Paola, P., Tranfaglia, E., D'Alessandro, A., Carifi, S., Porfido, F. A., Cerio, R., Grasso, A. M., Policicchio, D., and . Effects of the treatment with matrix on elderly people with chronic articular degeneration. Drug
- Crowley, D. C., Lau, F. C., Sharma, P., Evans, M., Guthrie, N., Bagchi, M., Bagchi, D., Dey, D. K., and Raychaudhuri, S. P. Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial. Int.J.Med.Sc PubMed
- Nickel, J. C., Egerdie, R. B., Steinhoff, G., Palmer, B., and Hanno, P. A multicenter, randomized, double-blind, parallel group pilot evaluation of the efficacy and safety of intravesical sodium chondroitin sulfate versus vehicle control in patients with
- Sawitzke, A. D., Shi, H., Finco, M. F., Dunlop, D. D., Harris, C. L., Singer, N. G., Bradley, J. D., Silver, D., Jackson, C. G., Lane, N. E., Oddis, C. V., Wolfe, F., Lisse, J., Furst, D. E., Bingham, C. O., Reda, D. J., Moskowitz, R. W., Williams, H. J.
- Wildi, L. M., Raynauld, J. P., Martel-Pelletier, J., Beaulieu, A., Bessette, L., Morin, F., Abram, F., Dorais, M., and Pelletier, J. P. Chondroitin sulphate reduces both cartilage volume loss and bone marrow lesions in knee osteoarthritis patients starti
- Pavelka and et al. Double-blind, dose effect study of oral cs 4 & 6 1200mg, 800mg, 200mg against placebo in the treatment of femorotibial osteoarthritis. Wular Rheumatol Liter 1998;27(suppl 2):63.
- Cerda C, Bruguera M, Parés A. Hepatotoxicity associated with glucosamine and chondroitin sulfate in patients with chronic liver disease. World J Gastroenterol 2013;19(32):5381-4. PubMed
- von Felden J, Montani M, Kessebohm K, Stickel F. Drug-induced acute liver injury mimicking autoimmune hepatitis after intake of dietary supplements containing glucosamine and chondroitin sulfate. Int J Clin Pharmacol Ther 2013;51(3):219-23. PubMed
- Provenza JR, Shinjo SK, Silva JM, Peron CR, Rocha FA. Combined glucosamine and chondroitin sulfate, once or three times daily, provides clinically relevant analgesia in knee osteoarthritis. Clin Rheumatol 2015;34:1455-62. PubMed
- Ossendza RA, Grandval P, Chinoune F, Rocher F, Chapel F, Bernardini D. [Acute cholestatic hepatitis due to glucosamine forte]. Gastroenterol Clin Biol. 2007 Apr;31(4):449-50.
- Greenlee H, Crew KD, Shao T, Kranwinkel G, Kalinsky K, Maurer M, Brafman L, Insel B, Tsai WY, Hershman DL. Phase II study of glucosamine with chondroitin on aromatase inhibitor-associated joint symptoms in women with breast cancer. Support Care Cancer 201 PubMed
- Chu EC, Huang KHK, Cheung G, Ng G, Lin A. Delayed Skin Allergy to Glucosamine Chondroitin Supplement. Cureus 2023;15(3):e36310. PubMed
- Lila AM, Alekseeva LI, Baranov AA, et al. Chondroitin sulfate and glucosamine combination in patients with knee and hip osteoarthritis: A long-term observational study in Russia. World J Orthop 2023;14(6):443-457. PubMed
Hyaluronic Acid 4 references
- Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
- U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
- Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
- Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed
Collagen Peptides 2 references
- Trc T, Bohmová J. Efficacy and tolerance of enzymatic hydrolysed collagen (EHC) vs. glucosamine sulphate (GS) in the treatment of knee osteoarthritis (KOA). Int Orthop. 2011;35(3):341-8. PubMed
- Evans M, Lewis ED, Zakaria N, Pelipyagina T, Guthrie N. A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity. J Cosmet Dermatol. 2021;20(3):825-834. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC