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Dietary supplement

Cordyceps CS-4 Strain Ingredients & Drug Interactions

by MRM Nutrition

Cordyceps CS-4 Strain label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Cordyceps CS-4 Strain against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Cordyceps CS-4 Strain is a dietary supplement by MRM Nutrition with 1 active ingredient. Its ingredients are commonly taken for fatigue and low energy, athletic performance and stamina, respiratory and lung support.Based on those ingredients, 249 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cordyceps sinensis CS-4 Mycelium Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Cordyceps CS-4 Strain by MRM Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Cordyceps CS-4 Strain by MRM Nutrition — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Cordyceps CS-4 Strain by MRM Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Oct 1, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: cordyceps sinensis CS-4 mycelium extract, a fungal preparation traditionally used to support energy and endurance. The capsule also contains cellulose, an inactive ingredient used as a filler.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Cordyceps's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: immune, respiratory, cardiovascular and metabolic energy.
  • We looked for evidence on: Asthma, Fatigue, Athletic performance, Cough, Stamina, Endurance — and 1 related terms.
  • The closest evidence on file: Cordyceps is rated "Possibly Ineffective" for Athletic performance (Natural Medicines).
  • Also on file: Cordyceps is rated "Insufficient Reliable Evidence To Rate" for Asthma, Cough, Fatigue.

The evidence for cordyceps is mixed and mostly limited. For athletic performance, the research suggests it's possibly ineffective — meaning studies haven't shown a reliable benefit.

For sexual dysfunction, asthma, chronic obstructive pulmonary disease (COPD), arrhythmia, and lung cancer, there simply isn't enough reliable evidence yet to say whether it works or doesn't. If you're considering cordyceps for any of these uses, talk it over with your doctor about what the current science actually supports.

The evidence, ingredient by ingredient Cordyceps

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cordyceps appears to be generally well tolerated when taken for up to a year, though the overall safety data is limited and product quality varies widely. The most common side effects are mild — abdominal discomfort, constipation, diarrhea, dry mouth, and throat discomfort — and taking it with food may help reduce them.

One case report describes a person who developed liver inflammation (jaundice) while taking a cordyceps product, though it's unclear whether cordyceps itself or a contaminant was responsible. The safety data advises against use during pregnancy and while breastfeeding, so talk with your doctor or pharmacist if either applies to you.

Side effects, ingredient by ingredient Cordyceps

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cordyceps.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
  • For scale: 249 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you're on blood thinners or antiplatelet drugs (such as warfarin, aspirin, or clopidogrel) — cordyceps may increase bleeding risk. Also flag it if you take immunosuppressants after an organ transplant or for autoimmune disease, or if you use testosterone therapy, since cordyceps may interfere with how these work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Cordyceps is one to check before you start, especially if you're on blood thinners, immunosuppressants, or testosterone therapy. The evidence for what it actually does is weak or missing for most uses.

If you're interested in trying it, bring your medication list and talk it through with your doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cordyceps CS-4 Strain, straight from the product label.

Brand MRM Nutrition
Barcode (UPC) 60949271030
Net contents 60 Vegan Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 319074
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cordyceps CS-4 Strain by MRM Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegan Capsule(s)
Maximum serving Sizes:
1 Vegan Capsule(s)
Servings per container
60
UPC/BARCODE
60949271030
IngredientAmount% DV
Cordyceps sinensis CS-4 Mycelium Extract750 mg--

Other ingredients: Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested usage: Take 1 capsule per day with a meal or as directed by your qualified healthcare provider.

Formulation

Supports immune, respiratory & cardiovascular systems Promotes normal metabolic energy

Vegan

Non GMO

Endurance

Contains no added milk, egg, peanut, tree nut, fish, or shellfish ingredients.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Made from recycled materials

FDA Statement of Identity

Dietary Supplement

Precautions

Contains soy and wheat.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Cordyceps CS-4 Strain by MRM Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Cordyceps CS-4 Strain label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Cordyceps CS-4 Strain by MRM Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegan Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Cordyceps sinensis CS-4 Mycelium Extract

Interacts with
249 drugs
750 mg per serving Form: Adenosine, Cordycepic Acid

Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited an...

Cordyceps sinensis CS-4 Mycelium Extract monograph & interactions

Other (inactive) ingredients: Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Cordyceps CS-4 Strain by MRM Nutrition Drug Interactions

Want to check YOUR meds against Cordyceps CS-4 Strain?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
249Drugs
241 Moderate 8 Minor

Ingredients driving the most interactions

Cordyceps sinensis CS-4 Mycelium Extract 249

Individual Drug Interactions

The ingredients in Cordyceps CS-4 Strain interact with 249 drugs. Click any drug to see the details.

1 of the 1 ingredient in Cordyceps CS-4 Strain interact with drugs. Each result below shows which ingredient is responsible. Cordyceps sinensis CS-4 Mycelium Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Cordyceps CS-4 Strain with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Cordyceps sinensis CS-4 Mycelium Extract3 drug types · 249 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
In vitro and animal research suggests that cordyceps extract inhibits platelet aggregation and function. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Animal and in vitro research suggests that cordyceps stimulates the immune system. However, limited clinical research suggests that taking cordyceps may lower the necessary therapeutic dose of the immunosuppressant cyclosporine, which suggests that cordyceps may have an immunosuppressive effect.

Likelihood Possible Evidence B
Testosterone

Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Animal research suggests that cordyceps can increase testosterone levels. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D
Cordyceps sinensis CS-4 Mycelium Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Cordyceps CS-4 Strain, from the product label.

MRM Nutrition

See all MRM Nutrition products
Name
MRM
Street Address
2665 Vista Pacific Dr
City
Oceanside
State
CA
ZipCode
92056
Phone Number
1-800-948-6296
Web Address
www.mrmnutrition.com
Pharmacist Counseling Corner

Cordyceps CS-4 Strain by MRM Nutrition: Common Questions

Does Cordyceps CS-4 Strain by MRM Nutrition interact with any medications?
Yes. Based on its ingredients, Cordyceps CS-4 Strain has a known interaction with 249 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cordyceps CS-4 Strain contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is cordyceps safe to take while pregnant or breastfeeding?
No — there isn't enough safety data. The facts advise against use during pregnancy and while breastfeeding. Talk with your doctor or pharmacist about whether cordyceps is right for you in these situations.
What are the side effects I might experience?
Most people tolerate it well, but you might notice abdominal discomfort, constipation, diarrhea, dry mouth, or throat discomfort. These are uncommon, and taking cordyceps with food may help reduce them. One rare case of liver inflammation has been reported, though it's unclear if cordyceps was the cause.
Will cordyceps actually boost my athletic performance?
The research suggests it's probably not effective for athletic performance. Evidence for sexual dysfunction, asthma, COPD, arrhythmia, and lung cancer is too limited to say either way.
How long can I safely take cordyceps?
Cordyceps has been studied for up to one year and appears generally well tolerated over that timeframe. For longer use, the safety data is limited, so check with your doctor or pharmacist.
Does this product contain fillers or other ingredients?
The only inactive ingredient is cellulose, used as a filler in the capsule. The active ingredient is cordyceps sinensis CS-4 mycelium extract.
Why is product quality variable if it's cordyceps?
Cordyceps products vary widely in strength and purity depending on how they're grown, extracted, and processed. That's why the facts note that evidence for safety and effectiveness is limited — what you're actually getting can differ from product to product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cordyceps CS-4 Strain label
Go deeper

The Full Monographs Behind Cordyceps CS-4 Strain’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Cordyceps

Interacts with 249 drugs

Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited and mostly low quality, so its benefits ar...

Read the full Cordyceps monograph →
Sources

Sources & How We Checked

Cordyceps CS-4 Strain's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cordyceps 14 references
  1. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of an ancient Chinese herbal medicine: Cordyceps sinensis: part I. J Altern Complement Med 1998;4:289-303.
  2. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: part II. J Altern Complement Med 1998;4:429-57.
  3. Chen YJ, Shiao MS, Lee SS, Wang SY. Effect of Cordyceps sinensis on the proliferation and differentiation of human leukemic U937 cells. Life Sci 1997;60:2349-59. PubMed
  4. Zhao Y. [Inhibitory effects of alcoholic extract of Cordyceps sinensis on abdominal aortic thrombus formation in rabbits]. Chung Hua I Hsueh Tsa Chih (Taipei) 1991;71:612-5, 42.
  5. Chen GZ, Chen GL, Sun T, et al. Effects of Cordyceps sinensis on murine T lymphocyte subsets. Chin Med J (English) 1991;104:4-8.
  6. Zhu XY, Yu HY. [Immunosuppressive effect of cultured Cordyceps sinensis on cellular immune response]. Chung Hsi I Chieh Ho Tsa Chih 1990;10:485-7, 454.
  7. Hsu, C. C., Huang, Y. L., Tsai, S. J., Sheu, C. C., and Huang, B. M. In vivo and in vitro stimulatory effects of Cordyceps sinensis on testosterone production in mouse Leydig cells. Life Sci 9-5-2003;73(16):2127-2136. PubMed
  8. Ikumoto, T., Sasaki, S., Namba, H., Toyama, R., Moritoki, H., and Mouri, T. [Physiologically active compounds in the extracts from tochukaso and cultured mycelia of Cordyceps and Isaria]. Yakugaku Zasshi 1991;111(9):504-509. PubMed
  9. Wu, T. N., Yang, K. C., Wang, C. M., Lai, J. S., Ko, K. N., Chang, P. Y., and Liou, S. H. Lead poisoning caused by contaminated Cordyceps, a Chinese herbal medicine: two case reports. Sci.Total Environ. 4-5-1996;182(1-3):193-195. PubMed
  10. Hong T, Zhang M, Fan J. Cordyceps sinensis (a traditional Chinese medicine) for kidney transplant recipients (Review). Cochrane Database Syst Rev. 2015;(10):CD009698. doi: 10.1002/14651858.CD009698.pub2.
  11. Zhang HW, Lin ZX, Tung YS, Kwan TH, Mok CK, Leung C, Chan LS. Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease (Review). Cochrane Database Syst Rev. 2014;(12):CD008353. doi: 10.1002/14651858.CD008353.pub2. PubMed
  12. Bee Yean O, Zoriah A. Efficacy of Cordyceps sinensis as an adjunctive treatment in hemodialysis patients: a systematic review and Meta-analysis. J Tradit Chin Med. 2019;39(1):1-14.
  13. Thurian D, Montani M, Stickel F. Drug-induced, mixed-type hepatitis following ingestion of Cordyceps sinensis. Int J Clin Pharmacol Ther 2022;60(2):115-120. PubMed
  14. Yu X, Mao Y, Shergis JL, et al. Effectiveness and safety of oral Cordyceps sinensis on stable COPD of GOLD stages 2-3: Systematic review and meta-analysis. Evid Based Complement Alternat Med. 2019;2019:4903671.

See these in context on the Cordyceps monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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