Cotton Ingredients & Drug Interactions
by Herb Pharm
What is this page for?
First and foremost: checking Cotton against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Cotton is a dietary supplement by Herb Pharm with 1 active ingredient. Its ingredients are commonly taken for menstrual cramps and bringing on menses, cooking oil (cottonseed oil), traditional use as a contraceptive (gossypol).We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Cotton by Herb Pharm
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: Cotton Root Bark Extract, Fresh. Cotton root bark has been used in traditional medicine, though modern research on its effects and safety is limited.
The liquid form also includes cane alcohol and glycerin as inactive ingredients.
Does it work?
Couldn't assess
The evidence for cotton root bark extract isn't established. The data we hold rates its use for malaria as insufficient — meaning we don't have reliable studies showing whether it works or doesn't.
How safe is it?
Some data gaps
Cotton root bark contains gossypol, a compound that can be toxic at higher doses, and the medicinal use of this extract hasn't been well studied. The product should be avoided during pregnancy because cotton has traditionally been used to stimulate the uterus and end pregnancy.
It's also not safe while breastfeeding — gossypol may pass to your infant and safety data is lacking. If you're pregnant, planning to become pregnant, or nursing, talk with your pharmacist or doctor before using this product.
Meds to double-check
No known interactions
No interactions are documented in our data for this ingredient. That doesn't mean none exist, so if you take any medications, use the interaction checker below with your exact drug names before starting.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and some safety-information gaps remain.
Cotton Root Bark Extract is not well researched in modern medicine and carries real safety concerns in pregnancy and lactation. If you're interested in it for a specific reason, check with your pharmacist first — especially if you're of childbearing age or nursing.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Cotton, straight from the product label.
| Brand | Herb Pharm |
|---|---|
| Barcode (UPC) | 090800000621 |
| Net contents | 1 Fluid Ounce(s); 30 mL |
| Market status | On market |
| Date entered into DSLD | Jun 25, 2025 |
| DSLD ID | 334515 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Organic, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Cotton by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Cotton Root Bark Extract, Fresh | 672 mg | -- |
Other ingredients: Cane Alcohol, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use Shake well before using Adults: Add 1 squeeze of the dropper bulb to 2 oz. of water or juice, 2 to 4 times per day. Best taken between meals.
Precautions
Caution: Seek expert medical advice before taking during pregnancy.
Keep out of the reach of children
Storage
Store away from heat & light
Formula
Gossypium hirsutum
Cotton Liquid Extract
Formulation
Optimal well-being
USDA Organic
Gluten-free
Certified organic by Organic Certifiers
Seals/Symbols
USDA Organic
FDA Statement of Identity
Herbal Supplement
FDA Disclaimer Statement
This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Cotton by Herb Pharm label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Cotton by Herb Pharm
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.7 mL Dosage formLiquid Servings per container42 Amounts shown are per serving.
Cotton Root Bark Extract, Fresh
No knowninteractions
Cotton is best known as a fiber and food-oil crop, but its root bark and seed have a long history in folk medicine for menstrual and reproductive comp...
Cotton Root Bark Extract, Fresh monograph & interactionsOther (inactive) ingredients: Cane Alcohol, Glycerin. These complete the product’s ingredient list but are not active constituents.
Cotton by Herb Pharm Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Cotton. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Cotton, from the product label.
Herb Pharm
See all Herb Pharm products- Name
- Herb Pharm
- City
- Williams
- State
- OR
- ZipCode
- 97544
- Phone Number
- 800-348-4372
- Web Address
- www.herb-pharm.com
Cotton by Herb Pharm: Common Questions
Does Cotton by Herb Pharm interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is this safe to take while pregnant?
Can I take this while breastfeeding?
Does cotton root bark actually work for malaria?
What is gossypol and why is it a concern?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Cotton is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Cotton’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Cotton's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 2 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Cotton 2 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Ankrah, N. A., Nyarko, A. K., Addo, P. G., Ofosuhene, M., Dzokoto, C., Marley, E., Addae, M. M., and Ekuban, F. A. Evaluation of efficacy and safety of a herbal medicine used for the treatment of malaria. Phytother.Res 2003;17(6):697-701. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC