No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Crampbark Ingredients & Drug Interactions

by Pure Herbs

Liquid Category: Botanical
No known interaction
The interaction bottom line No known interaction

Crampbark is a dietary supplement by Pure Herbs with 1 active ingredient. Its ingredients are commonly taken for menstrual cramps, muscle spasms, general cramping pain.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Crampbark by Pure Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Pure Herbs Crampbark contains one active ingredient: Crampbark Bark Extract. It's a liquid preparation of an herb traditionally used to address muscle tension and menstrual discomfort.

There are no other inactive ingredients listed.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Cramp Bark's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: alleviate menstrual cramping and support healthy menstruation.
  • We looked for evidence on: Dysmenorrhea, menstrual pain, period cramps.
  • The closest evidence on file: Cramp Bark is rated "Insufficient Reliable Evidence To Rate" for Dysmenorrhea (Natural Medicines).

The evidence for Crampbark isn't established in the data we hold. It's been used in traditional medicine for muscle cramps, menstrual pain (dysmenorrhea), kidney stones, and pregnancy-related leg cramps, but we don't have reliable study data to rate whether it actually works for any of those uses.

If you're thinking about using it for a specific concern, talk it over with your doctor or pharmacist to see if there's research behind it for your situation.

The evidence, ingredient by ingredient Cramp Bark

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Crampbark has limited human safety data. Because it's traditionally used rather than extensively studied in people, caution is warranted.

The safety information advises against use during pregnancy and breastfeeding — there isn't enough data to know it's safe in either situation. If you're pregnant, breastfeeding, or thinking about becoming pregnant, check with your doctor or pharmacist before taking it.

Side effects, ingredient by ingredient Cramp Bark

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That doesn't mean interactions won't happen — it means we don't hold information showing they do.

Run your medications through the search tool on this page, and talk with your doctor or pharmacist before taking Crampbark alongside any prescription or over-the-counter drug.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and some safety-information gaps remain.

Crampbark is a traditional herbal extract with no documented drug interactions, but human safety data are sparse. It's not proven to work for muscle cramps, menstrual pain, or other uses we have on file.

If you're pregnant or breastfeeding, the safety data advise against it. Talk with your own doctor or pharmacist before starting — they can help you decide if it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Crampbark, straight from the product label.

Brand Pure Herbs
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Dec 13, 2022
DSLD ID 279754
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Women (not pregnant or lactating), Girls: (All), Adult Female (18 - 50 Years), Seniors/Mature (>50 Years) - Women ONLY
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Crampbark by Pure Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 mL
Maximum serving Sizes:
2 mL
Servings per container
60
IngredientAmount% DV
Crampbark Bark Extract1977 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: For adults, mix 2 mL (abt. 1/2 tsp) of extract in 2 fl. oz (60 mL) water one time daily preferably with a meal.

Shake well before use

Formulation

Promotes the maintenance of good health. Helps to alleviate cramping during menstruation and supports a healthy menstruation.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Warning: Not intended for use by pregnant or nursing women. If you have a medical condition or are taking medication, consult your doctor prior to use.

Discontinue use and consult with your doctor if any adverse reactions occur.

Keep out of reach of children

Brand IP Statement(s)

Pure Herbs, Ltd. Natural Herbal Extracts

FDA Statement of Identity

Dietary Supplement

General Statements

"No expense has been spared to provide the finest nature has to offer."

See for yourself

Crampbark by Pure Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Crampbark by Pure Herbs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.

Crampbark Bark Extract

No known
interactions
1977 mg per serving

Cramp Bark is the dried bark of Viburnum opulus, traditionally used to ease muscle and menstrual cramps. Modern, high-quality human studies are very l...

Crampbark Bark Extract monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Crampbark by Pure Herbs Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Crampbark. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Crampbark, from the product label.

Pure Herbs

See all Pure Herbs products
Name
Pure Herbs, Ltd.
City
Sterling Heights
State
MI
Phone Number
(800) 860-4372
Web Address
www.pureherbs.com
Pharmacist Counseling Corner

Crampbark by Pure Herbs: Common Questions

Does Crampbark by Pure Herbs interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Crampbark. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Crampbark contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Crampbark if I'm pregnant?
The safety data advise against Crampbark during pregnancy because there isn't enough information to know it's safe. Talk with your doctor or pharmacist before taking it — they can help you weigh your options.
Is it safe to breastfeed while taking Crampbark?
There isn't enough safety information for breastfeeding. Check with your doctor or pharmacist before taking it while nursing.
Does Crampbark actually work for muscle cramps?
The evidence isn't established in the data we hold. It's used in traditional medicine for muscle cramps, but we don't have reliable study data showing it's effective. Your doctor can help you figure out whether it's worth trying for your situation.
Are there any known side effects?
No adverse effects are listed in the data we hold. That said, human safety data are limited because Crampbark is mainly used in traditional medicine.
What is Crampbark used for?
Traditionally it's been used for muscle cramps, menstrual pain, kidney stones, and pregnancy-related leg cramps. The evidence isn't established for any of these uses in the data we hold.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Crampbark label
Go deeper

The Full Monographs Behind Crampbark’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Crampbark's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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