T-W Ingredients & Drug Interactions
by Pure Herbs
What is this page for?
First and foremost: checking T-W against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
T-W is a dietary supplement by Pure Herbs with 4 active ingredients. Its ingredients are commonly taken for thyroid support, iodine source, weight management.Based on those ingredients, 1,126 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bladderwrack Algae Extract, Wild Lettuce aerial parts extract, Dulse Leaf Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against T-W by Pure Herbs
Ask about any prescription or over-the-counter medication and we check it for interactions with T-W by Pure Herbs — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of T-W by Pure Herbs
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
T-W contains four active ingredients: Bladderwrack Algae Extract, Dulse Leaf Extract, Wild Lettuce aerial parts extract, and Irish Moss Extract, supplied in a proprietary blend. The product has no inactive ingredients listed.
Does it work?
Not established
The product facts hold no effectiveness ratings for any of these ingredients' claimed uses. The evidence isn't established in the data we have on file.
How safe is it?
Well-documented data
Bladderwrack Algae Extract may be unsafe when taken by mouth due to its variable, high iodine content, which can disrupt thyroid function; the plant may also concentrate heavy metals. The most common adverse effects are goiter (enlarged thyroid), overactive thyroid, and underactive thyroid, though thyroid cancer has been reported rarely.
In one case, a patient taking lithium and a product containing Bladderwrack developed overactive thyroid; in another, a young adult taking a weight loss supplement containing Bladderwrack, dandelion, and boldo developed heart rhythm problems and fainting after three weeks. Dulse Leaf Extract is generally safe as a food but concentrated supplements may contain unpredictably high iodine and potassium with limited safety data.
Wild Lettuce aerial parts extract has limited human safety data, and large doses have caused sweating, rapid breathing, rapid heartbeat, dizziness, ringing in the ears, vision problems, pressure in the head, drowsiness, agitation, or respiratory depression. Irish Moss Extract is generally viewed as food but has variable iodine levels and possible heavy-metal content; one study reported constipation and diarrhea.
Bladderwrack and Dulse are not safe in pregnancy or while breastfeeding due to iodine and heavy-metal concerns; Wild Lettuce and Irish Moss lack enough safety data, so pregnancy and breastfeeding use should be discussed with your doctor or pharmacist.
Meds to double-check
Moderate interaction found
Check with your pharmacist before taking this product if you use lithium, antithyroid drugs, amiodarone, thyroid hormone, digoxin, potassium-sparing diuretics, ACE inhibitors, ARBs, blood thinners (anticoagulants), sedatives or CNS depressants, anticholinergic drugs, or drugs your liver processes via CYP2D6, CYP2C9, or CYP3A4 enzymes. Altogether, these interactions span 1,113 individual medications.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
This product is not for people taking lithium, heart rhythm drugs like amiodarone, thyroid medications, or drugs that manage blood potassium. If you take any antithyroid medication or digoxin, check with your pharmacist first.
Those who are pregnant or breastfeeding should avoid it due to iodine and safety concerns. Talk to your pharmacist about your medications before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about T-W, straight from the product label.
| Brand | Pure Herbs |
|---|---|
| Net contents | 4 Fluid Ounce(s); 120 mL |
| Market status | On market |
| Date entered into DSLD | Feb 23, 2025 |
| DSLD ID | 327252 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for T-W by Pure Herbs, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 1907 mg | -- |
| Bladderwrack Algae Extract | 0 NP | -- |
| Dulse Leaf Extract | 0 NP | -- |
| Wild Lettuce aerial parts extract | 0 NP | -- |
| Irish Moss Extract | 0 NP | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: For adults, mix 2 mL (abt. 1/2 tsp) of extract in 2 fl. oz (60 mL) water one time daily preferably with a meal.
Shake well before use
Formulation
To support healthy thyroid function.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Precautions
Warning: Not intended for use by pregnant or nursing women. If you have a medical condition or are taking medication, consult your doctor prior to use.
Discontinue use and consult with your doctor if any adverse reactions occur.
Keep out of reach of children
Brand IP Statement(s)
Pure Herbs, Ltd. Natural Herbal Extracts
FDA Statement of Identity
Dietary Supplement
General Statements
"No expense has been spared to provide the finest nature has to offer."
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
T-W by Pure Herbs label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in T-W by Pure Herbs
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Milliliter(s) Dosage formLiquid Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
T-W by Pure Herbs Drug Interactions
HelloPharmacist Interaction Report
T-W by Pure Herbs is a four-ingredient liquid blend that has documented interactions with a substantial number of medications.
The most serious concern involves its iodine-rich ingredients—Bladderwrack Algae Extract, Dulse Leaf Extract, and Irish Moss Extract—which interact moderately with lithium. When taken together, they've caused overactive thyroid (hyperthyroidism) in at least one patient; if you take lithium, thyroid hormone levels need close monitoring if you use this product.
Read the full breakdown — every affected drug type, severity by severity
All three iodine-containing ingredients also interact moderately with antithyroid drugs, amiodarone (a heart rhythm medication), and thyroid hormone replacements, since high iodine can push your thyroid either overactive or underactive depending on your history. Bladderwrack additionally has minor interactions with blood thinners (anticoagulants) and with three groups of drugs your liver processes (CYP2D6, CYP2C9, and CYP3A4 substrates)—though these haven't been seen in humans.
Dulse raises a moderate concern with digoxin (a heart drug) because it's rich in potassium, and also minor concerns with potassium-sparing diuretics, ACE inhibitors, and ARBs, all of which can raise blood potassium. Wild Lettuce aerial parts extract has moderate interactions with CNS depressants (sedatives, pain relievers, sleep aids) and anticholinergic drugs.
Altogether, these interactions span 1,113 individual medications. Use the medication checker below with your exact prescriptions before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against T-W?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in T-W interact with 1,126 drugs. Click any drug to see the details.
4 of the 4 ingredients in T-W interact with drugs. Each result below shows which ingredient is responsible. Bladderwrack Algae Extract Wild Lettuce aerial parts extract Dulse Leaf Extract Irish Moss Extract
AcepromazineAtravet
How Acepromazine interacts with T-W — through 1 ingredient. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractAnticholinergic Drugs, Cns Depressants Moderate
Interaction Summary
Studies report varying evidence on whether or not wild lettuce contains hyoscyamine, an anticholinergic drug.
Read the full Wild Lettuce Aerial Parts Extract + Acepromazine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative effects might cause additive therapeutic effects and adverse effects.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionBladderwrack Algae ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Bladderwrack Algae Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative effects might cause additive therapeutic effects and adverse effects.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Butalbital, Codeine interactionBladderwrack Algae ExtractCytochrome P450 2d6 (cyp2d6) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Bladderwrack Algae Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative effects might cause additive therapeutic effects and adverse effects.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionBladderwrack Algae ExtractCytochrome P450 2d6 (cyp2d6) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Bladderwrack Algae Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractAnticholinergic Drugs, Cns Depressants Moderate
Interaction Summary
Studies report varying evidence on whether or not wild lettuce contains hyoscyamine, an anticholinergic drug.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionBladderwrack Algae ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Bladderwrack Algae Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative effects might cause additive therapeutic effects and adverse effects.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Caffeine, Codeine interactionBladderwrack Algae ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Bladderwrack Algae Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative effects might cause additive therapeutic effects and adverse effects.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionBladderwrack Algae ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Bladderwrack Algae Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative effects might cause additive therapeutic effects and adverse effects.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionBladderwrack Algae ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Bladderwrack Algae Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractAnticholinergic Drugs Moderate
Interaction Summary
Studies report varying evidence on whether or not wild lettuce contains hyoscyamine, an anticholinergic drug.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Caffeine, Pyrilamine interactionBladderwrack Algae ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Bladderwrack Algae Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractAnticholinergic Drugs Moderate
Interaction Summary
Studies report varying evidence on whether or not wild lettuce contains hyoscyamine, an anticholinergic drug.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionBladderwrack Algae ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Bladderwrack Algae Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractCns Depressants, Anticholinergic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative effects might cause additive therapeutic effects and adverse effects.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionBladderwrack Algae ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Bladderwrack Algae Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractAnticholinergic Drugs Moderate
Interaction Summary
Studies report varying evidence on whether or not wild lettuce contains hyoscyamine, an anticholinergic drug.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionBladderwrack Algae ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Bladderwrack Algae Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractAnticholinergic Drugs Moderate
Interaction Summary
Studies report varying evidence on whether or not wild lettuce contains hyoscyamine, an anticholinergic drug.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionBladderwrack Algae ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Bladderwrack Algae Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractAnticholinergic Drugs Moderate
Interaction Summary
Studies report varying evidence on whether or not wild lettuce contains hyoscyamine, an anticholinergic drug.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionBladderwrack Algae ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Bladderwrack Algae Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractAnticholinergic Drugs Moderate
Interaction Summary
Studies report varying evidence on whether or not wild lettuce contains hyoscyamine, an anticholinergic drug.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionBladderwrack Algae ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Bladderwrack Algae Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractAnticholinergic Drugs Moderate
Interaction Summary
Studies report varying evidence on whether or not wild lettuce contains hyoscyamine, an anticholinergic drug.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionBladderwrack Algae ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Bladderwrack Algae Extract + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractAnticholinergic Drugs Moderate
Interaction Summary
Studies report varying evidence on whether or not wild lettuce contains hyoscyamine, an anticholinergic drug.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Chlorpheniramine, Phenylephrine interactionBladderwrack Algae ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Bladderwrack Algae Extract + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractAnticholinergic Drugs Moderate
Interaction Summary
Studies report varying evidence on whether or not wild lettuce contains hyoscyamine, an anticholinergic drug.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionBladderwrack Algae ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Bladderwrack Algae Extract + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractAnticholinergic Drugs Moderate
Interaction Summary
Studies report varying evidence on whether or not wild lettuce contains hyoscyamine, an anticholinergic drug.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionBladderwrack Algae ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Bladderwrack Algae Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractCns Depressants, Anticholinergic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative effects might cause additive therapeutic effects and adverse effects.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionBladderwrack Algae ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Bladderwrack Algae Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractAnticholinergic Drugs Moderate
Interaction Summary
Studies report varying evidence on whether or not wild lettuce contains hyoscyamine, an anticholinergic drug.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionBladderwrack Algae ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Bladderwrack Algae Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, Chlorpheniramine, PseudoephedrineAlka-Seltzer PLUS Liquid Gels, Children's Tylenol Cold, Codimal, Comtrex, Extra Strength Tylenol Allergy Sinus, Lorsin +3 more
How Acetaminophen, Chlorpheniramine, Pseudoephedrine interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractAnticholinergic Drugs Moderate
Interaction Summary
Studies report varying evidence on whether or not wild lettuce contains hyoscyamine, an anticholinergic drug.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionBladderwrack Algae ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Bladderwrack Algae Extract + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionAcetaminophen, Chlorzoxazone, CodeineAcetazone Forte C8, Parafon Forte C8
How Acetaminophen, Chlorzoxazone, Codeine interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative effects might cause additive therapeutic effects and adverse effects.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Chlorzoxazone, Codeine interactionBladderwrack Algae ExtractCytochrome P450 2d6 (cyp2d6) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Bladderwrack Algae Extract + Acetaminophen, Chlorzoxazone, Codeine interactionAcetaminophen, CodeineTylenol No.3, Tylenol w/ Codeine
How Acetaminophen, Codeine interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative effects might cause additive therapeutic effects and adverse effects.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Codeine interactionBladderwrack Algae ExtractCytochrome P450 2d6 (cyp2d6) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Bladderwrack Algae Extract + Acetaminophen, Codeine interactionAcetaminophen, Codeine, DoxylamineMersyndol
How Acetaminophen, Codeine, Doxylamine interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractAnticholinergic Drugs, Cns Depressants Moderate
Interaction Summary
Studies report varying evidence on whether or not wild lettuce contains hyoscyamine, an anticholinergic drug.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Codeine, Doxylamine interactionBladderwrack Algae ExtractCytochrome P450 2d6 (cyp2d6) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Bladderwrack Algae Extract + Acetaminophen, Codeine, Doxylamine interactionAcetaminophen, Codeine, MethocarbamolAcetaminophen, Codeine, Methocarbamol, Robaxacet 8
How Acetaminophen, Codeine, Methocarbamol interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative effects might cause additive therapeutic effects and adverse effects.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Codeine, Methocarbamol interactionBladderwrack Algae ExtractCytochrome P450 2d6 (cyp2d6) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Bladderwrack Algae Extract + Acetaminophen, Codeine, Methocarbamol interactionAcetaminophen, Dextromethorphan, Doxylamine, PseudoephedrineVicks NyQuil
How Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractAnticholinergic Drugs Moderate
Interaction Summary
Studies report varying evidence on whether or not wild lettuce contains hyoscyamine, an anticholinergic drug.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionBladderwrack Algae ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Bladderwrack Algae Extract + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Phenylpropanolamine, PyrilamineTheracaps
How Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interacts with T-W — through 2 ingredients. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractAnticholinergic Drugs Moderate
Interaction Summary
Studies report varying evidence on whether or not wild lettuce contains hyoscyamine, an anticholinergic drug.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interactionBladderwrack Algae ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Bladderwrack Algae Extract + Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interactionAcetaminophen, Dichloralantipyrine, IsomethepteneAmidrine, Midchlor, Migquin, Migratine
How Acetaminophen, Dichloralantipyrine, Isometheptene interacts with T-W — through 1 ingredient. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative effects might cause additive therapeutic effects and adverse effects.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Dichloralantipyrine, Isometheptene interactionAcetaminophen, Dichloralphenazone, IsomethepteneMidrin
How Acetaminophen, Dichloralphenazone, Isometheptene interacts with T-W — through 1 ingredient. Tap an ingredient for the detail:
Wild Lettuce Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative effects might cause additive therapeutic effects and adverse effects.
Read the full Wild Lettuce Aerial Parts Extract + Acetaminophen, Dichloralphenazone, Isometheptene interactionEach ingredient & the kinds of drugs it affects
For each ingredient in T-W with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Bladderwrack Algae Extract
Amiodarone (Cordarone)
Theoretically, combining Fucus vesiculosus with amiodarone might cause excessively high iodine levels.
Fucus vesiculosus contains high concentrations of iodine. Amiodarone contains 37.3% iodine and can increase iodine levels. Concomitant use might increase the risk of having excessive iodine levels and adversely affecting thyroid function. Monitor thyroid function.
Antithyroid Drugs
Due to its iodine content, Fucus vesiculosus might alter the effects of antithyroid drugs.
Fucus vesiculosus contains high concentrations of iodine. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking Fucus vesiculosus while using antithyroid drugs could alter the effects of the antithyroid drugs.
Lithium
Concomitant use of Fucus vesiculosus and lithium has resulted in hyperthyroidism.
There is a case of hyperthyroidism occurring in a patient taking Fucus vesiculosus and lithium. Monitor thyroid hormones closely in patients taking lithium and Fucus vesiculosus concomitantly.
Thyroid Hormone
Due to its iodine content, Fucus vesiculosus might alter the effects of thyroid hormone.
Fucus vesiculosus contains high concentrations of iodine. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking Fucus vesiculosus while using thyroid hormone could alter the effects of thyroid hormone.
Anticoagulant/Antiplatelet Drugs
Theoretically, taking Fucus vesiculosus with antiplatelet or anticoagulant drugs might increase the risk of bruising and bleeding.
In vitro evidence suggests that a constituent of Fucus vesiculosus, known as fucoidan, has anticoagulant effects. However, in clinical research, fucoidan does not seem to have significant anticoagulant activity when taken orally, possibly due to poor absorption.
Cytochrome P450 2C8 (Cyp2C8) Substrates
Theoretically, concomitant use of Fucus vesiculosus with CYP2C8 substrates might increase the risk for adverse effects.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, inhibits CYP2C8. This interaction has not been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, concomitant use of Fucus vesiculosus with CYP2C9 substrates might increase the risk for adverse effects.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, inhibits CYP2C9. This interaction has not been reported in humans.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, both inhibits and induces CYP2D6. This interaction has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, inhibits CYP3A4. This interaction has not been reported in humans.
Wild Lettuce aerial parts extract
Anticholinergic Drugs
Studies report varying evidence on whether or not wild lettuce contains hyoscyamine, an anticholinergic drug. If it does, it appears to be in very low amounts. Nevertheless, there have been case reports of individuals consuming large amounts of wild lettuce experiencing anticholinergic-related side effects, such as constipation, dry mouth, dizziness, and sweating. Therefore, if you are already taking a drug with anticholinergic effects, you should be cautious about combining it with wild lettuce as the risk of side effects may be increased.
Cns Depressants
Theoretically, concomitant use with drugs with sedative effects might cause additive therapeutic effects and adverse effects.
Dulse Leaf Extract
Amiodarine (Cordarone)
Theoretically, combining dulse with amiodarone might cause excessively high iodine levels.
Dulse is rich in iodine, and amiodarone contains 37.3% iodine and can increase iodine levels.
Antithyroid Drugs
Theoretically, due to its iodine content, dulse might alter the effects of antithyroid drugs.
Dulse is rich in iodine. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history.
Digoxin (Lanoxin)
Theoretically, dulse might increase the risk of hyperkalemia when taken with digoxin.
Dulse is rich in potassium, and digoxin can increase potassium levels in the blood. This interaction has not been demonstrated in humans.
Thyroid Hormone
Theoretically, due to its iodine content, dulse might alter the effects of thyroid hormone.
Dulse is rich in iodine. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Although dulse has been associated with a statistically significant increase in thyroid stimulating hormone (TSH) levels in clinical research, clinically significant increases have not been documented.
Ace Inhibitors (Aceis)
Theoretically, dulse might increase the risk of hyperkalemia when taken with ACEIs.
Dulse is rich in potassium. ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels. However, using these drugs while consuming dulse in quantities that provide larger amounts of potassium daily might increase the risk of hyperkalemia. Additionally, in vitro research suggests that dulse protein hydrolysates inhibit the activity of ACE. However, these effects have not been demonstrated in humans.
Angiotensin Receptor Blockers (Arbs)
Theoretically, dulse might increase the risk of hyperkalemia when taken with ARBs.
Dulse is rich in potassium. ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels. However, using these drugs while consuming dulse in quantities that provide higher amounts of potassium daily might increase the risk of hyperkalemia. Additionally, in vitro research suggests that dulse protein hydrolysates inhibit the activity of angiotensin converting enzyme (ACE). However, these effects have not been demonstrated in humans.
Potassium-Sparing Diuretics
Theoretically, dulse might increase the risk of hyperkalemia when taken with potassium-sparing diuretics.
Dulse is rich in potassium, and potassium-sparing diuretics can increase potassium levels in the blood. This interaction has not been shown in humans.
Irish Moss Extract
Amiodarone (Cordarone)
Theoretically, combining sea moss with amiodarone might cause excessively high iodine levels.
Amiodarone contains 37.3% iodine and can increase iodine levels. Concomitant use with sea moss, which contains approximately 4-7 mcg of iodine per gram, might increase the risk of adverse effects from iodine, including altered thyroid function.
Antithyroid Drugs
Due to its iodine content, sea moss might alter the effects of antithyroid drugs.
Sea moss contains approximately 4-7 mcg of iodine per gram. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking sea moss could theoretically alter the effects of antithyroid drugs.
Thyroid Hormone
Due to its iodine content, sea moss might alter the effects of thyroid hormone.
Sea moss contains approximately 4-7 mcg of iodine per gram. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking sea moss could theoretically alter the effects of thyroid hormone.
Brand information
Manufacturer and brand details for T-W, from the product label.
Pure Herbs
See all Pure Herbs products- Name
- Pure Herbs, Ltd.
- City
- Sterling Heights
- State
- MI
- Phone Number
- (800) 860-4372
- Web Address
- www.pureherbs.com
T-W by Pure Herbs: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind T-W’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Fucus Vesiculosus
Interacts with 891 drugsFucus vesiculosus (bladderwrack) is a brown seaweed rich in iodine that has been used traditionally for thyroid concerns, weight, and skin. There is little solid human evidence to support mo...
Read the full Fucus Vesiculosus monograph → Herb & supplement monographDulse
Interacts with 85 drugsDulse is a red seaweed eaten as a food in many coastal cultures and is a natural source of iodine, potassium, protein, and antioxidant compounds. As a food it is generally considered safe fo...
Read the full Dulse monograph → Herb & supplement monographWild Lettuce
Interacts with 393 drugsWild lettuce is a traditional herb used mainly for sleep, anxiety, and pain, but solid human research supporting these uses is very limited. Because its safety is not well studied, it should...
Read the full Wild Lettuce monograph → Herb & supplement monographSea Moss
Interacts with 22 drugsSea moss is a type of red seaweed that is naturally rich in iodine and several minerals, and it is popular as a 'whole-food' supplement. Strong human evidence for most of its health claims i...
Read the full Sea Moss monograph →Sources & How We Checked
T-W's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 28 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Fucus Vesiculosus 15 references
- Goodman GA, Rall TW, Nies AS, Taylor P. The Pharmacological Basis of Therapeutics, 9th ed.
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
- Phaneuf D, Cote I, Dumas P, et al. Evaluation of the contamination of marine algae (Seaweed) from the St. Lawrence River and likely to be consumed by humans. Environ Res 1999;80:S175-S182. PubMed
- Durig J, Bruhn T, Zurborn KH, et al. Anticoagulant fucoidan fractions from Fucus vesiculosus induce platelet activation in vitro. Thromb Res 1997;85:479-91. PubMed
- Conz PA, La Greca G, Benedetti P, et al. Fucus vesiculosus: a nephrotoxic alga? Nephrol Dial Transplant 1998;13:526-7.
- Ohye H, Fukata S, Kanoh M, et al. Thyrotoxicosis caused by weight-reducing herbal medicines. Arch Intern Med 2005;165:831-4. PubMed
- Okamura K, Inoue K, Omae T. A case of Hashimoto's thyroiditis with thyroid immunological abnormality manifested after habitual ingestion of seaweed. Acta Endocrinol (Copenh) 1978;88:703-12. PubMed
- Agarwal SC, Crook JR, Pepper CB. Herbal remedies -- how safe are they? A case report of polymorphic ventricular tachycardia/ventricular fibrillation induced by herbal medication used for obesity. Int J Cardiol 2006;106:260-1. PubMed
- Sterling JB, Heymann WR. Potassium iodide in dermatology: a 19th century drug for the 21st century-uses, pharmacology, adverse effects, and contraindications. J Am Acad Dermatol 2000;43:691-7. PubMed
- Catania, M. A., Oteri, A., Caiello, P., Russo, A., Salvo, F., Giustini, E. S., Caputi, A. P., and Polimeni, G. Hemorrhagic cystitis induced by an herbal mixture. South.Med.J. 2010;103(1):90-92. PubMed
- Cumashi, A., Ushakova, N. A., Preobrazhenskaya, M. E., D'Incecco, A., Piccoli, A., Totani, L., Tinari, N., Morozevich, G. E., Berman, A. E., Bilan, M. I., Usov, A. I., Ustyuzhanina, N. E., Grachev, A. A., Sanderson, C. J., Kelly, M., Rabinovich, G. A., I
- Irhimeh, M. R., Fitton, J. H., and Lowenthal, R. M. Pilot clinical study to evaluate the anticoagulant activity of fucoidan. Blood Coagul.Fibrinolysis 2009;20(7):607-610. PubMed
- Arbaizar, B. and Llorca, J. [Fucus vesiculosus induced hyperthyroidism in a patient undergoing concomitant treatment with lithium]. Actas Esp.Psiquiatr. 2011;39(6):401-403.
- Church FC, Meade JB, Treanor RE, and et al. Antithrombin activity of fucoidan. The interaction of fucoidan with heparin cofactor II, antithrombin III, and thrombin. J Biol Chem 2-25-1989;264(6):3618-3623. DOI
- Mathew L, Burney M, Gaikwad A, et al. Preclinical evaluation of safety of fucoidan extracts from Undaria pinnatifida and Fucus vesiculosus for use in cancer treatment. Integr Cancer Ther 2017;16(4):572-84.
Dulse 5 references
- Malta D, Arcand J, Ravindran A, Floras V, Allard JP, Newton GE. Adequate intake of potassium does not cause hyperkalemia in hypertensive individuals taking medications that antagonize the renin angiotensin aldosterone system. Am J Clin Nutr 2016 Oct;104(4 PubMed
- Allsopp P, Crowe W, Bahar B, et al. The effect of consuming Palmaria palmata-enriched bread on inflammatory markers, antioxidant status, lipid profile and thyroid function in a randomised placebo-controlled intervention trial in healthy adults. Eur J Nutr PubMed
- McGrath BM, Harmon JP, Bishop G. Palmaria palmata (Dulse) as an unusual maritime aetiology of hyperkalemia in a patient with chronic renal failure: a case report. J Med Case Rep. 2010;4:301. PubMed
- Furuta T, Miyabe Y, Yasui H, Kinoshita Y, Kishimura H. Angiotensin I converting enzyme inhibitory peptides derived from phycobiliproteins of dulse Palmaria palmata. Mar Drugs. 2016;14(2):32. PubMed
- Takase T, Nakamura A, Miyoshi H, et al. Effects of Palmaria palmata on lipid metabolism and glycemic control in participants with hypercholesterolemia in a randomized double-blind placebo-controlled trial. Phytother Res. 2020.
Wild Lettuce 5 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Besharat S, Besharat M, Jabbari A. Wild lettuce (Lactuca virosa) toxicity. BMJ Case Rep. 2009;2009. pii: bcr06.2008.0134.
- Mullins ME, Horowitz BZ. The case of the salad shooters: intravenous injection of wild lettuce extract. Vet Hum Toxicol. 1998;40(5):290-1.
Sea Moss 3 references
- Darias-Rosales J, Rubio C, Gutiérrez ÁJ, Paz S, Hardisson A. Risk assessment of iodine intake from the consumption of red seaweeds (Palmaria palmata and Chondrus crispus). Environ Sci Pollut Res Int 2020;27(36):45737-45741. PubMed
- U.S. Department of Agriculture (USDA). Agricultural Research Service. FoodData Central. Seaweed, irishmoss, raw. April 2019. Available at: https://fdc.nal.usda.gov/fdc-app.html#/food-details/168456/nutrients. Accessed Aug. 30, 2022.
- Palmieri B, Vadalà M, Laurino C. Clinical effects of overwintered-stressed Chondrus Crispus and non-overwintered-stressed Chondrus crispus dietary supplementations. Asian J Med Sci. 2018; 9(6): 7-13. DOI
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC