No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 5 ingredients. Check your meds →
Dietary supplement

Dentalflora Ingredients & Drug Interactions

by Biocidin Botanicals

Tablet Or Pill Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Dentalflora is a dietary supplement by Biocidin Botanicals with 5 active ingredients. Its ingredients are commonly taken for tooth decay prevention, dry mouth, sugar substitute.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Dentalflora by Biocidin Botanicals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • “Dentalflora Probiotic Blend” is a proprietary blend — the label gives one combined amount (105 mg) without saying how much of each component you get.

Dentalflora is a five-ingredient probiotic tablet aimed at oral health. It contains two Lactobacillus species (salivarius and paracasei), Lactobacillus reuteri, Streptococcus salivarius BLIS M18 strain, and Xylitol — a naturally occurring sugar alcohol.

The inactive ingredients are spearmint leaf extract, inulin, stearic acid, hydroxypropyl cellulose, and spearmint flavor.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Daily oral probiotics.
  • We looked for evidence on: Dental caries, Dental plaque, Dry mouth, Gingivitis, Oral health, Periodontal health — and 2 related terms.
  • The strongest evidence on file: Xylitol is rated "Likely Effective" for Dental caries (Natural Medicines).
  • Also on file: Xylitol is rated "Insufficient Reliable Evidence To Rate" for Dental plaque, Dry mouth, Gingivitis.

Xylitol in this product is likely effective for dental caries (cavities) — that's backed by solid evidence. The same ingredient may help with ear infections (otitis media), though the evidence is weaker.

We don't have established effectiveness ratings in our data for the probiotic strains themselves, so we can't speak to how well they work for oral health on their own.

The evidence, ingredient by ingredient Xylitol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Xylitol at food amounts is generally well tolerated, though high doses (30–40 grams) can cause loose stools, gas, and bloating. At the doses in a tablet, you're unlikely to run into that.

Minor stinging of the mouth or nose has been reported in some people. Importantly, xylitol is toxic to dogs — keep this product away from pets.

The probiotic bacteria don't have documented adverse effects in the data we hold, though allergic reactions to xylitol itself are rare.

Side effects, ingredient by ingredient Xylitol

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for the ingredients we could check. We couldn't verify the probiotic bacteria against medication databases, so if you take immunosuppressing drugs or have questions about safety with your specific prescriptions, ask your pharmacist to review your full list.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Dentalflora is a reasonable pick if you're looking for an oral probiotic with xylitol, which has solid evidence for cavity prevention. It's generally well tolerated at typical doses.

If you take immunosuppressants or have a severely compromised immune system, talk with your pharmacist first. Keep it away from dogs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Dentalflora, straight from the product label.

Brand Biocidin Botanicals
Barcode (UPC) 899870002241
Net contents 30 Mint Tablet(s)
Market status On market
Date entered into DSLD Jul 25, 2024
DSLD ID 314060
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Dentalflora by Biocidin Botanicals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
30
UPC/BARCODE
899870002241
IngredientAmount% DV
Lactobacillus salivarius27 mg--
Lactobacillus paracasei31 mg--
Xylitol293 mg--
Lactobacillus reuteri27 mg--
Dentalflora Probiotic Blend105 mg--
Streptococcus salivarius BLIS M1820 mg--

Other ingredients: Spearmint leaf extract, Inulin, Stearic Acid, Hydroxypropyl Cellulose, Spearmint flavor

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use Ages 4 and up, slowly dissolve one tablet in mouth and swallow. Can be taken anytime, but bedtime is most effective. If using an oral rinse, wait 30 minutes after rinsing before taking Dentalflora. For best results, use with Dentalcidin Oral care system.

Precautions

Warning: Consult your physician before using any supplement, especially if you are pregnant, nursing, have a medical condition, or are taking medication.

Discontinue use should adverse reactions occur.

Keep out of reach of children and pets.

Storage

Store in a cool, dry place.

Formulation

5 billion CFU at time of manufacture. 3 billion CFU at expiration.

Promotes healthy teeth and gums

This product is made without dairy, gluten, soy, egg, animal products, artificial coloring or flavoring.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

Daily oral probiotics

BLIS M18

General Statements

Smile

Dentist formulated

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

BLIS and BLIS M18 are trademarks of Blis Technologies Limited.

See for yourself

Dentalflora by Biocidin Botanicals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Dentalflora by Biocidin Botanicals

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Xylitol

No known
interactions
293 mg per serving

Xylitol is a sugar alcohol used as a low-calorie sweetener that has the best-supported benefit for reducing cavities, especially in chewing gum or loz...

Xylitol monograph & interactions

Dentalflora Probiotic Blend

105 mg per serving
  • › Lactobacillus salivarius
  • › Lactobacillus paracasei
  • › Lactobacillus reuteri
  • › Streptococcus salivarius BLIS M18

Other (inactive) ingredients: Spearmint leaf extract, Inulin, Stearic Acid, Hydroxypropyl Cellulose, Spearmint flavor. These complete the product’s ingredient list but are not active constituents.

Interaction report

Dentalflora by Biocidin Botanicals Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Dentalflora. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Dentalflora, from the product label.

Biocidin Botanicals

See all Biocidin Botanicals products
Name
Biocidin Botanicals
Street Address
PO box 2499
City
Aptos
State
CA
ZipCode
95001
Phone Number
800-775-4140
Web Address
biocidin.com
Pharmacist Counseling Corner

Dentalflora by Biocidin Botanicals: Common Questions

Does Dentalflora by Biocidin Botanicals interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Dentalflora. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Dentalflora contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does Xylitol really help prevent cavities?
Yes — xylitol is likely effective for dental caries (cavities). It may also help with ear infections, though that evidence is less robust. The probiotic strains in this product don't have established effectiveness data in our files.
Will this upset my stomach?
Xylitol at food or tablet amounts is generally well tolerated. High doses (30–40 grams) can cause loose stools, gas, or bloating, but you won't hit those levels with a single tablet. The probiotic bacteria themselves don't have documented stomach issues.
Is it safe for my dog?
No — xylitol is highly toxic to dogs. Keep Dentalflora completely out of reach of pets.
Can I use this if I'm pregnant or nursing?
The product facts don't include pregnancy or breastfeeding safety data. Talk with your doctor or pharmacist about whether this probiotic tablet is right for you during pregnancy or while nursing.
What are the inactive ingredients?
The tablet contains spearmint leaf extract, inulin, stearic acid, hydroxypropyl cellulose, and spearmint flavor — these are binders, fillers, and flavoring, not active ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Dentalflora is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Dentalflora label
Go deeper

The Full Monographs Behind Dentalflora’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Dentalflora's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Xylitol 7 references
  1. Martindale W. Martindale the Extra Pharmacopoeia. Pharmaceutical Press, 1999.
  2. Weissman JD, Fernandez F, Hwang PH. Xylitol nasal irrigation in the management of chronic rhinosinusitis: a pilot study. Laryngoscope 2011;121:2468-72. PubMed
  3. Okamoto K, Kagami M, Kawai M, et al. Anaphylaxis to xylitol diagnosed by skin prick test and basophil activation test. Allergol Int. 2019;68(1):130-131. PubMed
  4. Rabago D, Kille T, Mundt M, Obasi C. Results of a RCT assessing saline and xylitol nasal irrigation for CRS and fatigue in Gulf War illness. Laryngoscope Investig Otolaryngol 2020;5(4):613-620.
  5. Wołyniec W, Szwarc A, Kasprowicz K, et al. Impact of hydration with beverages containing free sugars or xylitol on metabolic and acute kidney injury markers after physical exercise. Front Physiol 2022;13:841056. PubMed
  6. Bordier V, Teysseire F, Drewe J, et al. Effects of a 5-week intake of erythritol and xylitol on vascular function, abdominal fat and glucose tolerance in humans with obesity: a pilot trial. BMJ Nutr Prev Health 2023;6(2):264-272. PubMed
  7. Margulis I, Cohen-Kerem R, Stein N, et al. Xylitol nasal spray for prevention of recurrent acute otitis media in children: A prospective two-center cohort study. Int J Pediatr Otorhinolaryngol 2024;176:111818. PubMed

See these in context on the Xylitol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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