No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 3 of 9 ingredients. Check your meds →
Dietary supplement

DGST Ingredients & Drug Interactions

by Loomis Enzymes

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

DGST is a dietary supplement by Loomis Enzymes with 9 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of DGST by Loomis Enzymes

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 9 active ingredients.
  • “Proprietary Enzyme Blend” is a proprietary blend — the label gives one combined amount (244 mg) without saying how much of each component you get.

DGST contains nine active digestive enzymes designed to break down carbohydrates, proteins, fats, and fiber in food. Protease breaks down proteins; lipase handles fats; lactase breaks down milk sugar; amylase works on starches; and the others (cellulase, invertase, glucoamylase, hemicellulase, diastase) target various carbohydrates and plant fibers.

The product also contains three inactive ingredients: phytase, cellulose, and water.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Digestive enzyme support.
  • We looked for evidence on: Dyspepsia, Lactose intolerance, Bloating, Gas, Indigestion.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).
  • Also on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.

Lactase in this product is rated effective for lactose intolerance — if you struggle to digest milk and dairy, it can help. For lipase and dyspepsia (indigestion), the evidence isn't strong enough yet to rate it reliably.

The same goes for lipase and inflammatory bowel disease. We don't hold effectiveness data for the other enzymes in the blend.

The evidence, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase Lactase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The three enzymes we have data for are generally well tolerated in most adults, though digestive upset or allergic reactions are possible — these are rare but worth knowing about. Protease and lipase should be avoided in pregnancy unless your doctor prescribes them, and both need medical guidance during breastfeeding because safety data is limited.

Lactase is rated likely safe in pregnancy, but still check with your doctor before regular use. One case of allergic reaction to lactase powder (from occupational exposure) and rare reports of allergic reactions to protease have been documented, mostly from airborne or skin exposure in industrial settings rather than from taking supplements by mouth.

Side effects, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase Lactase

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 3 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That said, we hold no interaction data for amylase, cellulase, invertase, glucoamylase, hemicellulase, or the proprietary blend.

If you take any prescription drugs, verify your exact medications using the checker on this page.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

DGST is a reasonable choice if you're looking for digestive support, especially if you're lactose intolerant — lactase is proven to help there. If you're pregnant or breastfeeding, talk to your pharmacist or doctor first; the data on these enzymes during pregnancy and nursing is limited or cautionary.

Run your medications through the checker to be safe, even though no interactions are documented for the ingredients we have on file.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about DGST, straight from the product label.

Brand Loomis Enzymes
Barcode (UPC) 697706042016
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Feb 23, 2025
DSLD ID 327428
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for DGST by Loomis Enzymes, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
90
UPC/BARCODE
697706042016
IngredientAmount% DV
Amylase0 NP--
Protease0 NP--
Lipase0 NP--
Lactase0 NP--
Cellulase0 NP--
Invertase0 NP--
Glucoamylase0 NP--
Hemicellulase0 NP--
Diastase0 NP--
Proprietary Enzyme Blend244 mg--

Other ingredients: Phytase, Cellulose, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

pHBS pH Balancing system

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Keep out of reach of children

Note: Consult your physician before using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Do not use if inner or outer seal is broken, torn, or missing.

Storage

To ensure freshness and potency, keep bottle tightly closed and store in a cool, dry place.

FDA Statement of Identity

A Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions for use: Take 2 capsules, 3 times daily with meals or as directed.

See for yourself

DGST by Loomis Enzymes label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in DGST by Loomis Enzymes

These are the 9 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Enzyme Blend

244 mg per serving
  • › Amylase
  • Protease
  • Lipase
  • Lactase
  • › Cellulase
  • › Invertase
  • › Glucoamylase
  • › Hemicellulase
  • › Diastase

Other (inactive) ingredients: Phytase, Cellulose, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

DGST by Loomis Enzymes Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in DGST. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for DGST, from the product label.

Loomis Enzymes

See all Loomis Enzymes products
Name
Loomis Enzymes, LLC
City
Fitchburg
State
Wisconsin
ZipCode
53719
Phone Number
1-800-614-4400
Web Address
www.loomisenzymes.com
Pharmacist Counseling Corner

DGST by Loomis Enzymes: Common Questions

Does DGST by Loomis Enzymes interact with any medications?
We do not currently list a known interaction for the mapped ingredients in DGST. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
DGST contains 9 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will DGST help me if I'm lactose intolerant?
Yes — lactase, one of the enzymes in this blend, is rated effective for lactose intolerance. It breaks down the milk sugar that your body has trouble digesting on its own.
Is it safe to take DGST while pregnant?
Lactase is rated likely safe in pregnancy, but protease and lipase should be avoided unless your doctor prescribes them. Check with your doctor or pharmacist before regular use, since safety data for these enzymes is limited.
Can DGST cause allergic reactions?
Allergic reactions are rare but possible. One case of allergic reaction to lactase powder and occupational cases of allergic reactions to protease have been reported, mostly from inhaled or skin exposure rather than from taking the supplement by mouth. If you have known allergies to enzymes or enzyme-containing products, mention it when you pick this up.
What if I'm breastfeeding — is DGST safe?
Lactase has limited but reassuring safety data for breastfeeding. Protease and lipase have little safety data during nursing, so ask your doctor or pharmacist first before taking them regularly.
Does DGST help with indigestion?
The evidence for lipase and indigestion isn't strong enough yet to rate reliably. You might benefit, but we can't say for certain based on the data we hold.
Are there any fillers in DGST?
The capsule contains three inactive ingredients: phytase, cellulose, and water. Those are the only other ingredients besides the nine active enzymes.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if DGST is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

DGST label
Sources

Sources & How We Checked

DGST's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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