Interactions on record — worth a quick check against your medications. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

Psor-Rbs Ingredients & Drug Interactions

by Loomis Enzymes

Psor-Rbs label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Psor-Rbs against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Psor-Rbs is a dietary supplement by Loomis Enzymes with 4 active ingredients. Its ingredients are commonly taken for high cholesterol, liver health, brain and memory support.Based on those ingredients, 226 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Borage Oil, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Psor-Rbs by Loomis Enzymes

Ask about any prescription or over-the-counter medication and we check it for interactions with Psor-Rbs by Loomis Enzymes — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Psor-Rbs by Loomis Enzymes

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 2 of its 4 active ingredients.
  • “Proprietary Enzyme Blend” is a proprietary blend — the label gives one combined amount (84 mg) without saying how much of each component you get.

Psor-Rbs has 4 active ingredients: lipase, cellulase, lecithin, and borage oil powder. Lipase and cellulase are digestive enzymes that break down fats and plant fibers in food.

Lecithin is a naturally occurring fat-like substance often used to support digestion and nutrient absorption. Borage oil is a plant extract rich in compounds that some people use for inflammatory and immune support.

The capsule also contains microcrystalline cellulose, cellulose, water, and phytase as inactive ingredients — these are binders and fillers that help form and stabilize the capsule.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: pH balancing system.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence for these ingredients is mixed and incomplete. Lipase and cellulase have insufficient reliable evidence to rate them for digestive complaints like indigestion or inflammatory bowel disease — we just don't have enough solid trial data yet.

Lecithin is rated likely ineffective for age-related memory loss, and insufficient evidence for anxiety and other conditions. Borage oil is rated possibly ineffective for eczema.

Overall, the data we hold does not establish strong effectiveness for the conditions people typically use digestive enzyme blends to address.

The evidence, ingredient by ingredient Lecithin Lipase Borage

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lipase is generally well tolerated but should only be used under medical guidance if you have serious digestive conditions. There isn't much safety data on lipase during pregnancy or breastfeeding, so talk to your doctor first.

Lecithin is generally considered safe and likely safe in pregnancy; common side effects are mild (abdominal discomfort, diarrhea, fullness, nausea), but it can trigger allergic skin reactions in people with egg or soy allergies. Borage oil is generally well tolerated, though it may cause bloating, belching, diarrhea, and soft stools.

Borage is rated likely unsafe in pregnancy because of concerns about liver-toxic alkaloids and effects on the uterus. During breastfeeding, safety data is limited and PA contamination is a worry, so it's best avoided.

Make sure any borage ingredient is certified free of pyrrolizidine alkaloids (PA).

Side effects, ingredient by ingredient Lecithin Lipase Borage

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 3 matched ingredients can interact with medications — Borage.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 227 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Psor-Rbs, check if you take blood thinners or antiplatelet drugs (like warfarin, clopidogrel, or aspirin) — borage oil may increase bleeding risk. Also check if you take phenothiazine antipsychotics or drugs that induce the CYP3A4 liver enzyme, as borage carries Moderate interactions with both.

Your pharmacist can search your exact medications on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is an enzyme blend with borage, so it's mainly for people looking for digestive support — though evidence for that use is limited. If you take blood thinners, antipsychotics, or certain other medications, check with us first.

Pregnant or breastfeeding? Skip the borage in this product and talk to your doctor about the enzymes.

Start a conversation with your pharmacist before you try it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Psor-Rbs, straight from the product label.

Brand Loomis Enzymes
Barcode (UPC) 697706011708
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Feb 23, 2025
DSLD ID 327547
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Psor-Rbs by Loomis Enzymes, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 Capsule(s)
Maximum serving Sizes:
4 Capsule(s)
Servings per container
45
UPC/BARCODE
697706011708
IngredientAmount% DV
Lipase0 NP--
Cellulase0 NP--
Lecithin400 mg--
Proprietary Enzyme Blend84 mg--
Borage Oil, Powder400 mg--

Other ingredients: Microcrystalline Cellulose, Cellulose, Water, Phytase

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

pHBS pH Balancing System

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Keep out of reach of children

Note: Consult your physician before using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Do not use if inner or outer seal is broken, torn, or missing.

Contains soy

Storage

To ensure freshness and potency, keep bottle tightly closed and store in a cool, dry place.

FDA Statement of Identity

A Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions for use: Take 4 capsules 3 times daily with meals, or as directed.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Psor-Rbs by Loomis Enzymes label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Psor-Rbs label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Psor-Rbs by Loomis Enzymes

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size4 Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Lecithin

No known
interactions
400 mg per serving Form: Soy

Lecithin is a natural fatty substance found in foods and made by the body that is widely used as a supplement and food emulsifier. Evidence supporting...

Lecithin monograph & interactions

Proprietary Enzyme Blend

84 mg per serving

Borage Oil, Powder

Interacts with
226 drugs
400 mg per serving

Borage is a Mediterranean herb whose seed oil is rich in gamma-linolenic acid (GLA), an omega-6 fatty acid studied mostly for skin conditions and arth...

Borage Oil, Powder monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Cellulose, Water, Phytase. These complete the product’s ingredient list but are not active constituents.

Interaction report

Psor-Rbs by Loomis Enzymes Drug Interactions

Want to check YOUR meds against Psor-Rbs?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
226Drugs
226 Moderate

Ingredients driving the most interactions

Borage Oil, Powder 226

Individual Drug Interactions

The ingredients in Psor-Rbs interact with 226 drugs. Click any drug to see the details.

1 of the 4 ingredients in Psor-Rbs interact with drugs. Each result below shows which ingredient is responsible. Borage Oil, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Psor-Rbs with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Borage Oil, Powder3 drug types · 226 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In healthy individuals, borage seed oil supplementation does not seem to affect platelet aggregation. However, gamma-linolenic acid, a constituent of borage seed oil, seems to decrease platelet aggregation by 45% and increase the risk of bleeding by 40% in animal and clinical research.

Likelihood Possible Evidence B
Cytochrome P450 3A4 (Cyp3A4) Inducers

Theoretically, taking borage with drugs that induce CYP3A4 might increase levels of pyrrolizidine alkaloid (PA) toxic metabolites.
Although borage seed oil contains little to no PAs, some borage plant parts, such as the leaf, flower, and seed, can contain hepatotoxic PAs. Hepatotoxic PAs are substrates of CYP3A4, which converts these chemicals into toxic metabolites. Tell patients to avoid borage preparations that are not certified and labeled as hepatotoxic PA-free.

Likelihood Possible Evidence D
Phenothiazines

Theoretically, taking borage sed oil with phenothiazines might increase the risk of seizures.
Borage seed oil contains gamma-linolenic acid (GLA). There is concern that taking supplements containing GLA might cause seizures, or lower the seizure threshold, when taken with phenothiazines. This is based on limited data from two reports published in the 1980s. In one report, three patients with schizophrenia who had received phenothiazines developed EEG changes suggestive of temporal lobe epilepsy after starting treatment with evening primrose, another source of GLA. However, none experienced an actual seizure. In the other report, two patients with schizophrenia who were stabilized on phenothiazines developed seizures when evening primrose 4 grams daily was added. One of these patients had a prior history of seizures. It is unclear whether evening primrose had any additive epileptogenic effects with the phenothiazines, but there is no evidence that taking GLA-containing supplements alone can cause seizures.

Likelihood Possible Evidence D
Borage Oil, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Psor-Rbs, from the product label.

Loomis Enzymes

See all Loomis Enzymes products
Name
Loomis Enzymes, LLC
City
Fitchburg
State
Wisconsin
ZipCode
53719
Phone Number
1-800-614-4400
Web Address
www.loomisenzymes.com
Pharmacist Counseling Corner

Psor-Rbs by Loomis Enzymes: Common Questions

Does Psor-Rbs by Loomis Enzymes interact with any medications?
Yes. Based on its ingredients, Psor-Rbs has a known interaction with 226 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Psor-Rbs contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
No — borage oil in this product is rated likely unsafe in pregnancy because of concerns about liver-toxic alkaloids and potential uterine effects. Talk to your doctor or pharmacist about whether the enzymes alone might help, but don't use this product as formulated.
Can I take this while breastfeeding?
The safety data on borage while breastfeeding is limited, and there's a concern about alkaloid contamination, so it's best to avoid this product. Lipase and lecithin safety while breastfeeding isn't well studied either, so check with your healthcare provider first.
What are the side effects I should expect?
The most common are digestive ones — bloating, belching, diarrhea, soft stools, and mild abdominal discomfort or nausea. If you have an egg or soy allergy, lecithin might trigger a skin reaction. Serious side effects are rare.
Does this actually help with digestion?
The evidence we hold doesn't clearly show it works for indigestion or digestive conditions. Lipase and cellulase don't have enough reliable trial data to rate them, and the product hasn't been studied as a whole.
What if I'm allergic to eggs or soy?
Let us know — lecithin in this product can cause allergic skin reactions in people with those allergies.
Is the borage oil in this product safe from liver-toxic alkaloids?
The safety notes say that seed oil certified pyrrolizidine alkaloid (PA)-free is better tolerated, so ask the manufacturer if theirs carries that certification. Other borage plant parts can contain harmful alkaloids, but this product contains borage oil powder, which typically has little to no PAs.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Psor-Rbs label
Go deeper

The Full Monographs Behind Psor-Rbs’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lecithin

Lecithin is a natural fatty substance found in foods and made by the body that is widely used as a supplement and food emulsifier. Evidence supporting most of its health claims is limited, t...

Read the full Lecithin monograph → Herb & supplement monograph

Lipase

Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...

Read the full Lipase monograph → Herb & supplement monograph

Borage

Interacts with 226 drugs

Borage is a Mediterranean herb whose seed oil is rich in gamma-linolenic acid (GLA), an omega-6 fatty acid studied mostly for skin conditions and arthritis with mixed results. The plant's le...

Read the full Borage monograph →
Sources

Sources & How We Checked

Psor-Rbs's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 21 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Lecithin 9 references
  1. Buchman AL, Dubin M, Jenden D, et al. Lecithin increases plasma free choline and decreases hepatic steatosis in long-term total parenteral nutrition patients. Gastroenterology 1992;102:1363-70.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Chatellier G, Lacomblez L. Tacrine (tetrahydroaminoacridine; THA) and lecithin in senile dementia of the Alzheimer type: a multicentre trial. Groupe Francais d'Etude de la Tetrahydroaminoacridine. BMJ 1990;300:495-9.
  4. Gelenberg AJ, Dorer DJ, Wojcik JD, et al. A crossover study of lecithin treatment of tardive dyskinesia. J Clin Psychiatry 1990;51:149-53.
  5. Little A, Levy R, Chuaqui-Kidd P, Hand D. A double-blind, placebo controlled trial of high-dose lecithin in Alzheimer's disease. J Neurol Neurosurg Psychiatry 1985;48:736-42. PubMed
  6. Palm M, Moneret-Vautrin DA, Kanny G, et al. Food allergy to egg and soy lecithins. Allergy 1999;54:1116-7. PubMed
  7. Drachman DA, Glosser G, Fleming P, et al. Memory decline in the aged: treatment with lecithin and physostigmine. Neurology 1982;32:944-50. PubMed
  8. Gelenberg, A. J., Doller-Wojcik, J. C., and Growdon, J. H. Choline and lecithin in the treatment of tardive dyskinesia: preliminary results from a pilot study. Am J Psychiatry 1979;136(6):772-776. PubMed
  9. Electronic Code of Federal Regulations. Title 21, Chapter 1, Subchapter B, Part 184: Direct food substances affirmed as Generally Recognized as Safe. Subpart B - listing of specific substances affirmed as GRAS. Sec. 184.1400 Lecithin. Available at: https:

See these in context on the Lecithin monograph →

Borage 11 references
  1. Guivernau M, Meza N, Barja P, Roman O. Clinical and experimental study on the long-term effect of dietary gamma-linolenic acid on plasma lipids, platelet aggregation, thromboxane formation, and prostacyclin production. Prostaglandins Leukot Essent Fatty A PubMed
  2. WHO working group. Pyrrolizidine alkaloids. Environmental Health Criteria, 80. WHO: Geneva, 1988.
  3. Fan YY, Chapkin RS. Importance of dietary gamma-linolenic acid in human health and nutrition. J Nutr 1998;128:1411-4.
  4. Takwale A, Tan E, Agarwal S, et al. Efficacy and tolerability of borage oil in adults and children with atopic eczema: randomised, double blind, placebo controlled, parallel group trial. BMJ 2003;327:1385. PubMed
  5. Chojkier M. Hepatic sinusoidal-obstruction syndrome: toxicity of pyrrolizidine alkaloids. J Hepatol 2003;39:437-46. PubMed
  6. Roeder E. Medicinal plants in Europe containing pyrrolizidine alkaloids. Pharmazie 1995;50:83-98.
  7. Wang YP, Yan J, Fu PP, Chou MW. Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid. Toxicol Lett 2005;155:411-20. PubMed
  8. Holman CP and Bell AF. A trial of evening primrose oil in the treatment of chronic schizophrenia. J Orhtomolecular Psych 1983;12:302-304.
  9. Vaddadi KS. The use of gamma-linolenic acid and linoleic acid to differentiate between temporal lobe epilepsy and schizophrenia. Prostaglandins Med 1981;6(4):375-379. PubMed
  10. Bard, J. M., Luc, G., Jude, B., Bordet, J. C., Lacroix, B., Bonte, J. P., Parra, H. J., and Duriez, P. A therapeutic dosage (3 g/day) of borage oil supplementation has no effect on platelet aggregation in healthy volunteers. Fundam.Clin.Pharmacol. 1997;1
  11. Puri BK. The safety of evening primrose oil in epilepsy. Prostaglandins Leukotrienes Essential Fatty Acids 2007;77:101-3. PubMed

See these in context on the Borage monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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