Digest Select Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Digest Select against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Digest Select is a dietary supplement by Moss Nutrition with 11 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Digest Select by Moss Nutrition
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Digest Select contains 11 active ingredients, all digestive enzymes designed to help break down food. The product includes lipase (which breaks down fats), lactase (which breaks down milk sugar), and several proteases (which break down proteins).
It also contains amylase and glucoamylase (which break down carbohydrates), plus invertase, peptidase, alpha-galactosidase, and acid maltase — all part of the digestive enzyme family. The capsule itself is made from hypromellose with microcrystalline cellulose, stearate, and silicon dioxide as inactive ingredients.
Does it work?
Strong evidence
The evidence on these enzymes is mixed. Lactase is effective for lactose intolerance — if you have trouble digesting milk sugar, this ingredient can help.
For the others, the data we hold shows insufficient reliable evidence to rate how well they work for dyspepsia (indigestion), inflammatory bowel disease, prematurity, or colic. The proteases (Protease I, II, and III) have no effectiveness ratings on file.
In other words, we don't have solid proof that most of the enzymes in this blend improve digestion or address specific conditions.
How safe is it?
Well-documented data
Lipase and lactase are generally well tolerated when used as directed. The proteases (Protease I, II, and III) are also commonly well tolerated in most adults but may cause digestive upset or allergic reactions in some people.
A rare case of contact dermatitis and allergic reaction to lactase powder has been reported, though it involved occupational exposure. No adverse effects have been reported in adults taking supplemental lipase, but a full safety evaluation hasn't been done.
For pregnancy, there isn't enough data on lipase or the proteases to know if they're safe — talk with your doctor before use. Lactase is likely safe in pregnancy if your doctor approves.
During breastfeeding, lactase is likely safe, but lipase and the proteases have limited safety data — check with your healthcare provider first.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. However, we do not hold interaction data for amylase, peptidase, invertase, glucoamylase, alpha-galactosidase, or acid maltase — so those components could potentially interact with medications and we simply cannot verify.
Use the medication checker on this page to search your specific drugs.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
Digest Select is a straightforward enzyme blend for people looking to support digestion, especially those with lactose intolerance. The proteases and other enzymes are generally well tolerated, though digestive upset or rare allergic reactions are possible.
If you're pregnant or breastfeeding, or if you have a serious digestive condition, talk with your pharmacist or doctor before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Digest Select, straight from the product label.
| Brand | Moss Nutrition |
|---|---|
| Barcode (UPC) | M152 |
| Net contents | 180 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Oct 24, 2022 |
| DSLD ID | 275550 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Digest Select by Moss Nutrition, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Amylase | 0 NP | -- |
| Lipase | 0 NP | -- |
| Lactase | 0 NP | -- |
| Peptidase | 0 NP | -- |
| Invertase | 0 NP | -- |
| Glucoamylase | 0 NP | -- |
| Alpha-Galactosidase | 0 NP | -- |
| Protease I | 0 NP | -- |
| Protease II | 0 NP | -- |
| Digestive Enzyme Blend | 110 mg | -- |
| Acid Maltase | 0 NP | -- |
| Protease III | 0 NP | -- |
Other ingredients: Hypromellose, Microcrystalline Cellulose, Stearate, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: 1 capsule at start of meal, or as directed by your healthcare professional.
Precautions
Warning: If you are taking medication, have a medical condition or an upcoming medical procedure, or are pregnant or nursing, consult a physician before using.
If adverse reactions occur, discontinue use & consult your healthcare practitioner.
Keep out of reach of children.
Storage
Store sealed in a cool, dry place.
Brand IP Statement(s)
Moss Nutrition M Professional Supplements Est. 1991
Formula
Broad Spectrum Plant-Based Enzymes
FDA Statement of Identity
Dietary Supplement
Formulation
Does not contain gluten.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Digest Select by Moss Nutrition label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Digest Select by Moss Nutrition
These are the 11 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Digestive Enzyme Blend
- › Amylase
- › Lipase
- › Lactase
- › Peptidase
- › Invertase
- › Glucoamylase
- › Alpha-Galactosidase
- › Protease I
- › Protease II
- › Acid Maltase
- › Protease III
Other (inactive) ingredients: Hypromellose, Microcrystalline Cellulose, Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Digest Select by Moss Nutrition Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Digest Select. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Digest Select, from the product label.
Moss Nutrition
See all Moss Nutrition products- Name
- Moss Nutrition Products, Inc.
- Street Address
- 380 Russell Street
- City
- Hadley
- State
- MA
- ZipCode
- 01035
- Phone Number
- 800-851-5444
- Web Address
- www.mossnutrition.com
Digest Select by Moss Nutrition: Common Questions
Does Digest Select by Moss Nutrition interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will Digest Select help with lactose intolerance?
Can I take this if I'm pregnant?
Are there any side effects?
Is this product for indigestion?
Can I breastfeed while taking this?
What do these enzymes do?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Digest Select is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Digest Select’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph → Herb & supplement monographLactase
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...
Read the full Lactase monograph → Herb & supplement monographProteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph →Sources & How We Checked
Digest Select's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 5 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC