No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 3 of 11 ingredients. Check your meds →
Dietary supplement

Digest Select Ingredients & Drug Interactions

by Moss Nutrition

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Digest Select is a dietary supplement by Moss Nutrition with 11 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Digest Select by Moss Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 11 active ingredients.
  • “Digestive Enzyme Blend” is a proprietary blend — the label gives one combined amount (110 mg) without saying how much of each component you get.

Digest Select contains 11 active digestive enzymes designed to help break down food. The checked ingredients include lipase (which breaks down fats), lactase (which breaks down milk sugar), and three proteolytic enzymes — protease I, II, and III — that work on proteins.

The product also contains several other enzyme components we couldn't fully evaluate: amylase, peptidase, invertase, glucoamylase, alpha-galactosidase, and acid maltase. Inactive ingredients include a vegetable capsule (hypromellose), microcrystalline cellulose, vegetable stearate, and silicon dioxide.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Digestive enzyme support for meal digestion.
  • We looked for evidence on: Dyspepsia, Lactose intolerance, Indigestion, Bloating, Gas, Fat malabsorption.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).
  • Also on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.

Lactase in this product is effective for lactose intolerance — that's well established. For the other enzymes, the evidence isn't clear enough yet to make a strong claim.

Lipase, for example, shows insufficient reliable evidence for inflammatory bowel disease (IBD) or indigestion (dyspepsia). The proteolytic enzymes don't have effectiveness ratings on file.

If you're looking for enzyme support for a specific digestive condition, your pharmacist can help you figure out whether this blend makes sense for your situation.

The evidence, ingredient by ingredient Lipase Lactase Proteolytic Enzymes (proteases)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lipase and lactase are generally well tolerated when taken as directed. With lipase, if you have a serious digestive condition, use it only under medical guidance.

Lactase has one rare report of contact allergy in someone handling the powder, though oral use hasn't shown adverse effects. The proteolytic enzymes may cause mild digestive upset or allergic reactions in some people, and rarely, occupational exposure to airborne proteases has triggered allergic rhinitis or asthma — though that's not typical for oral supplements.

For pregnancy, lipase has little safety data, so talk to your doctor; lactase is likely safe. Breastfeeding safety data is limited for both lipase and the proteases, so check with your healthcare provider first.

Side effects, ingredient by ingredient Lipase Lactase Proteolytic Enzymes (proteases)

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 3 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check in this product. Still, use the medication search tool on this page to verify your exact prescriptions and over-the-counter drugs — it only takes a moment.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Digest Select is a multi-enzyme blend for people wanting digestive support, especially those with lactose intolerance (where lactase is proven effective). Most adults tolerate it well, but if you have serious digestive conditions or are pregnant or breastfeeding, check with your doctor or pharmacist first.

No medication interactions are documented for the ingredients we could check, though we'd still recommend running your exact drugs through our checker to be thorough.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Digest Select, straight from the product label.

Brand Moss Nutrition
Barcode (UPC) M100
Net contents 90 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Oct 24, 2022
DSLD ID 275541
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Digest Select by Moss Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
UPC/BARCODE
M100
IngredientAmount% DV
Amylase0 NP--
Lipase0 NP--
Lactase0 NP--
Peptidase0 NP--
Invertase0 NP--
Glucoamylase0 NP--
Alpha-Galactosidase0 NP--
Protease I0 NP--
Protease II0 NP--
Digestive Enzyme Blend110 mg--
Acid Maltase0 NP--
Protease III0 NP--

Other ingredients: Hypromellose, Microcrystalline Cellulose, Vegetable Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: 1 capsule at start of each meal, or as directed by your healthcare professional.

Precautions

Warning: If you are taking medication, have a medical condition or an upcoming medical procedure, or are pregnant or nursing, consult a physician before using.

If adverse reactions occur, discontinue use & consult your healthcare practitioner.

Keep out of reach of children.

Storage

Store sealed in a cool, dry place.

Brand IP Statement(s)

Moss Nutrition M Professional Supplements Est. 1991

Formula

Broad Spectrum Plant-Based Enzymes

FDA Statement of Identity

Dietary Supplement

Formulation

Does not contain gluten.

See for yourself

Digest Select by Moss Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Digest Select by Moss Nutrition

These are the 11 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Digestive Enzyme Blend

110 mg per serving

Other (inactive) ingredients: Hypromellose, Microcrystalline Cellulose, Vegetable Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Digest Select by Moss Nutrition Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Digest Select. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Digest Select, from the product label.

Moss Nutrition

See all Moss Nutrition products
Name
Moss Nutrition Products, Inc.
Street Address
380 Russell Street
City
Hadley
State
MA
ZipCode
01035
Phone Number
800-851-5444
Web Address
www.mossnutrition.com
Pharmacist Counseling Corner

Digest Select by Moss Nutrition: Common Questions

Does Digest Select by Moss Nutrition interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Digest Select. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Digest Select contains 11 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does Digest Select work for lactose intolerance?
Yes — the lactase enzyme in the blend is effective for lactose intolerance. Lactase breaks down milk sugar so your body can digest dairy products more easily.
Can I take this while pregnant?
Lactase is likely safe during pregnancy. Lipase and the proteolytic enzymes have limited safety data, so talk to your doctor before starting — they can decide what's right for your situation.
What will I experience from the proteolytic enzymes?
Proteolytic enzymes break down proteins to aid digestion. We don't have effectiveness ratings for them yet, so we can't promise a specific benefit. Some people may experience mild digestive upset or, rarely, an allergic reaction.
Are there any reported side effects?
No adverse effects have been reported in adults for most of these enzymes. Rarely, someone might have an allergic reaction to proteases. Lactase has one case report of contact allergy in someone handling the powder, but oral use is safe.
Is this safe while breastfeeding?
Safety data is limited for lipase and the proteases during breastfeeding. Lactase acts only in the gut, so it's likely low risk, but ask your doctor or pharmacist before regular use.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Digest Select is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Digest Select label
Sources

Sources & How We Checked

Digest Select's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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