Digestive Stimulation Complex Chocolate Flavor Ingredients & Drug Interactions
by TerraVita
What is this page for?
First and foremost: checking Digestive Stimulation Complex Chocolate Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Digestive Stimulation Complex Chocolate Flavor is a dietary supplement by TerraVita with 3 active ingredients. Its ingredients are commonly taken for urinary tract and 'flushing' support, joint pain and arthritis, mild fluid retention (diuretic).Based on those ingredients, 578 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Boldo Glycerite Liquid Extract, Birch Glycerite Liquid Extract, Prickly Ash Tree Glycerite Liquid Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Digestive Stimulation Complex Chocolate Flavor by TerraVita
Ask about any prescription or over-the-counter medication and we check it for interactions with Digestive Stimulation Complex Chocolate Flavor by TerraVita — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Digestive Stimulation Complex Chocolate Flavor by TerraVita
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This product has three active ingredients in liquid extract form: birch glycerite, boldo glycerite, and northern prickly ash glycerite. The inactive ingredients are glycerin (a natural sweetener and preservative) and chocolate flavoring.
Each ingredient is included in a proprietary blend, which means the exact amounts of each aren't listed separately on the label.
Does it work?
Couldn't assess
The evidence we hold doesn't establish that any of these ingredients work for digestive stimulation or any other condition. Birch, boldo, and prickly ash all carry insufficient reliable evidence ratings across the conditions they're used for — meaning the studies either don't exist, are too small or low-quality, or are too mixed to draw firm conclusions.
If digestive support is what you're after, talk with your doctor or pharmacist about what's actually proven to help.
How safe is it?
Well-documented data
Boldo is the safety concern here. It contains ascaridole, a liver toxin, and documented cases of hepatotoxicity — including elevated liver enzymes and jaundice — have been reported with boldo supplements, even though food amounts are generally well tolerated.
Common side effects with boldo at medicinal doses include abdominal pain, nausea, and vomiting. Birch can cause allergic reactions in people sensitive to birch pollen or birch products, and one case of allergic skin contact dermatitis has been reported.
Prickly ash has limited safety data and is best used short-term only. None of these ingredients should be used during pregnancy or breastfeeding — birch and prickly ash lack enough safety information, and boldo is considered unsafe because it may stimulate the uterus.
Meds to double-check
Moderate interaction found
Before using this product, double-check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (the boldo interaction is Moderate), drugs that affect the liver, lithium, warfarin, tacrolimus, water pills, acid-reducing medications like H2-blockers, antacids, or proton pump inhibitors. Boldo's liver toxicity risk is the most serious concern, so liver health and any liver disease should be discussed with your provider.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
The boldo in this product carries documented risks of liver damage and multiple moderate-severity drug interactions, especially with blood thinners and immunosuppressants. If you take any prescription medications, check them against the interaction tool on this page before using this product — and talk with your doctor or pharmacist first, especially if you have liver disease or take warfarin, tacrolimus, lithium, or acid-reducing drugs.
This product isn't recommended during pregnancy or breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 21, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Digestive Stimulation Complex Chocolate Flavor, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Digestive Stimulation Complex Chocolate Flavor by TerraVita, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 0.13 mL | -- |
| Birch Glycerite Liquid Extract | 0 NP | -- |
| Boldo Glycerite Liquid Extract | 0 NP | -- |
| Prickly Ash Tree Glycerite Liquid Extract | 0 NP | -- |
Other ingredients: Glycerin, Chocolate flavor
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
Copyright 2018 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.
Formula
Glycerite liquid extract (1:5)
Formulation
Alcohol free
Suggested/Recommended/Usage/Directions
Suggested Use: Take 25-40 drops of extract in a small amount of warm water 3-4 times daily. Shake well before using.
Precautions
Keep away from children.
Do not use if safety seal around cap is broken or missing.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Digestive Stimulation Complex Chocolate Flavor by TerraVita label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Digestive Stimulation Complex Chocolate Flavor by TerraVita
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size25 Drop(s) Dosage formLiquid Servings per container227 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
Other (inactive) ingredients: Glycerin, Chocolate flavor. These complete the product’s ingredient list but are not active constituents.
Digestive Stimulation Complex Chocolate Flavor by TerraVita Drug Interactions
HelloPharmacist Interaction Report
TerraVita's Digestive Stimulation Complex Chocolate Flavor contains three active ingredients — birch, boldo, and prickly ash — and the boldo component carries the most serious interactions documented here.
Boldo interacts with blood thinners (anticoagulants) and the immunosuppressant tacrolimus at Moderate severity; it may also affect lithium levels and drugs that harm the liver (hepatotoxic drugs). Altogether, these interactions span 579 individual medications.
Read the full breakdown — every affected drug type, severity by severity
Birch carries a Minor interaction with water pills (diuretics), theoretically interfering with how well they work. Prickly ash has Minor interactions with three types of acid-reducing medications — H2-blockers, antacids, and proton pump inhibitors (PPIs) — because reports suggest prickly ash raises stomach acid and could weaken their effect.
Boldo's liver concerns are the biggest flag here: it contains ascaridole, a known liver toxin, and cases of liver damage including elevated liver enzymes and jaundice have been reported in people taking boldo supplements. If you take any prescription medication — especially blood thinners like warfarin, immunosuppressants, lithium, acid reducers, or diuretics — run your exact drugs through the interaction checker below before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Digestive Stimulation Complex Chocolate Flavor?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Digestive Stimulation Complex Chocolate Flavor interact with 578 drugs. Click any drug to see the details.
3 of the 3 ingredients in Digestive Stimulation Complex Chocolate Flavor interact with drugs. Each result below shows which ingredient is responsible. Boldo Glycerite Liquid Extract Birch Glycerite Liquid Extract Prickly Ash Tree Glycerite Liquid Extract
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking boldo with anticoagulant/antiplatelet drugs might increase the risk of bleeding.
Read the full Boldo Glycerite Liquid Extract + Abciximab interactionAbiraterone
How Abiraterone interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking boldo with anticoagulant/antiplatelet drugs might increase the risk of bleeding.
Read the full Boldo Glycerite Liquid Extract + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking boldo with anticoagulant/antiplatelet drugs might increase the risk of bleeding.
Read the full Boldo Glycerite Liquid Extract + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractAnticoagulant/antiplatelet Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with anticoagulant/antiplatelet drugs might increase the risk of bleeding.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Digestive Stimulation Complex Chocolate Flavor — through 2 ingredients. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Caffeine, Pyrilamine interactionBirch Glycerite Liquid ExtractDiuretic Drugs Minor
Interaction Summary
Theoretically, birch might interfere with diuretic therapy.
Read the full Birch Glycerite Liquid Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Digestive Stimulation Complex Chocolate Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Digestive Stimulation Complex Chocolate Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Boldo Glycerite Liquid Extract
Anticoagulant/Antiplatelet Drugs
Theoretically, taking boldo with anticoagulant/antiplatelet drugs might increase the risk of bleeding.
Animal and in vitro research shows that boldine, a constituent of boldo, has antiplatelet activity. In one case report, an adult taking a combination of boldo and fenugreek with warfarin experienced an increase in international normalized ratio (INR); however, it is unclear if this effect was due to boldo, fenugreek, the combination, or another factor.
Hepatotoxic Drugs
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Boldo leaf contains ascaridole, a known liver toxin. Many cases of hepatotoxicity, including elevated liver transaminase levels and jaundice, have been reported in patients taking boldo.
Lithium
Theoretically, taking boldo with lithium might increase the levels and clinical effects of lithium.
Boldo is believed to have diuretic effects. Theoretically, these diuretic effects might reduce the excretion of lithium. The dose of lithium might need to be decreased.
Tacrolimus (Prograf)
Taking boldo with tacrolimus may decrease the levels and clinical effects of tacrolimus, potentially increasing the risk of transplant rejection.
In one case report, a patient with a long-term history of stable tacrolimus levels developed subtherapeutic levels after taking boldo 300 mg twice daily orally for several weeks. Tacrolimus levels returned to normal after discontinuing boldo. However, the mechanism of this interaction is unclear.
Warfarin (Coumadin)
A combination of boldo and fenugreek was thought to be associated with an increased international normalized ratio (INR) in a female on warfarin. It is not clear if boldo, fenugreek, or the combination played a role in this interaction. Therefore, boldo may have additive effects with warfarin.
Birch Glycerite Liquid Extract
Diuretic Drugs
Theoretically, birch might interfere with diuretic therapy.
Prickly Ash Tree Glycerite Liquid Extract
Antacids
Theoretically, northern prickly ash might decrease the effectiveness of antacids.
There are reports that northern prickly ash increases stomach acid.
H2-Blockers
Theoretically, northern prickly ash might decrease the effectiveness of H2-blockers.
There are reports that northern prickly ash increases stomach acid.
Proton Pump Inhibitors (Ppis)
Theoretically, northern prickly ash might decrease the effectiveness of PPIs.
There are reports that northern prickly ash increases stomach acid.
Brand information
Manufacturer and brand details for Digestive Stimulation Complex Chocolate Flavor, from the product label.
TerraVita
See all TerraVita products- Name
- ZooScape LLC
- Phone Number
- 844-449-0444
- Web Address
- www.ZooScape.com
Digestive Stimulation Complex Chocolate Flavor by TerraVita: Common Questions
Does Digestive Stimulation Complex Chocolate Flavor by TerraVita interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant or nursing?
What are the side effects I should watch for?
Does this actually help with digestion?
Is boldo safe to take long-term?
What is prickly ash supposed to do?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Digestive Stimulation Complex Chocolate Flavor is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Digestive Stimulation Complex Chocolate Flavor’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Birch
Interacts with 75 drugsBirch is a tree whose leaves, bark, and sap are used in traditional remedies, most often as a mild diuretic or for joint and urinary complaints. Solid human evidence is limited, and birch is...
Read the full Birch monograph → Herb & supplement monographBoldo
Interacts with 482 drugsBoldo is a South American shrub whose leaves are traditionally used for digestive and gallbladder complaints, but good human evidence is very limited. The leaves and oil contain ascaridole,...
Read the full Boldo monograph → Herb & supplement monographNorthern Prickly Ash
Interacts with 36 drugsNorthern Prickly Ash is a North American shrub whose bark and berries have a long history in folk medicine, especially for toothache, joint pain, and sluggish digestion. Modern scientific ev...
Read the full Northern Prickly Ash monograph →Sources & How We Checked
Digestive Stimulation Complex Chocolate Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 16 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Birch 4 references
- Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
- Lahti, A. and Hannuksela, M. Immediate contact allergy to birch leaves and sap. Contact Dermatitis 1980;6(7):464-465. PubMed
- Allam JP, Wuestenberg E, Wolf H, et al. Immunologic response and safety in birch pollen sublingual versus oral vestibule immunotherapy: a pilot study. J Allergy Clin Immunol. 2014;133(6):1757-9.e3. PubMed
- Meyer-Hoffert U, Brasch J. Allergic contact dermatitis caused by betulin-containing triterpene extract from the outer bark of birch (Betula alba). Contact Dermatitis. 2013;68(6):382-3.
Boldo 10 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Lambert J, Cormier J. Potential interaction between warfarin and boldo-fenugreek. Pharmacotherapy 2001;21:509-12. PubMed
- Piscaglia F, Leoni S, Venturi A, et al. Caution in the use of boldo in herbal laxatives: a case of hepatotoxicity. Scand J Gastroenterol 2005;40:236-9. PubMed
- Agarwal SC, Crook JR, Pepper CB. Herbal remedies -- how safe are they? A case report of polymorphic ventricular tachycardia/ventricular fibrillation induced by herbal medication used for obesity. Int J Cardiol 2006;106:260-1. PubMed
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Northern Prickly Ash 2 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
See these in context on the Northern Prickly Ash monograph →
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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