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Dietary supplement

Digestive Stimulation Complex Chocolate Flavor Ingredients & Drug Interactions

by TerraVita

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Digestive Stimulation Complex Chocolate Flavor is a dietary supplement by TerraVita with 3 active ingredients. Its ingredients are commonly taken for urinary tract and 'flushing' support, joint pain and arthritis, mild fluid retention (diuretic).Based on those ingredients, 578 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Boldo Glycerite Liquid Extract, Birch Glycerite Liquid Extract, Prickly Ash Tree Glycerite Liquid Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Digestive Stimulation Complex Chocolate Flavor by TerraVita

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (0.13 mL) without saying how much of each component you get.

This product has three active ingredients in liquid extract form: birch glycerite, boldo glycerite, and northern prickly ash glycerite. The inactive ingredients are glycerin (a natural sweetener and preservative) and chocolate flavoring.

Each ingredient is included in a proprietary blend, which means the exact amounts of each aren't listed separately on the label.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The label doesn't state a purpose we can grade — see each ingredient's own graded uses on its monograph instead.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold doesn't establish that any of these ingredients work for digestive stimulation or any other condition. Birch, boldo, and prickly ash all carry insufficient reliable evidence ratings across the conditions they're used for — meaning the studies either don't exist, are too small or low-quality, or are too mixed to draw firm conclusions.

If digestive support is what you're after, talk with your doctor or pharmacist about what's actually proven to help.

The evidence, ingredient by ingredient Birch Boldo Northern Prickly Ash

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Boldo is the safety concern here. It contains ascaridole, a liver toxin, and documented cases of hepatotoxicity — including elevated liver enzymes and jaundice — have been reported with boldo supplements, even though food amounts are generally well tolerated.

Common side effects with boldo at medicinal doses include abdominal pain, nausea, and vomiting. Birch can cause allergic reactions in people sensitive to birch pollen or birch products, and one case of allergic skin contact dermatitis has been reported.

Prickly ash has limited safety data and is best used short-term only. None of these ingredients should be used during pregnancy or breastfeeding — birch and prickly ash lack enough safety information, and boldo is considered unsafe because it may stimulate the uterus.

Side effects, ingredient by ingredient Birch Boldo Northern Prickly Ash

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Northern Prickly Ash, Birch, Boldo.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; lithium.
  • For scale: 579 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before using this product, double-check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (the boldo interaction is Moderate), drugs that affect the liver, lithium, warfarin, tacrolimus, water pills, acid-reducing medications like H2-blockers, antacids, or proton pump inhibitors. Boldo's liver toxicity risk is the most serious concern, so liver health and any liver disease should be discussed with your provider.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

The boldo in this product carries documented risks of liver damage and multiple moderate-severity drug interactions, especially with blood thinners and immunosuppressants. If you take any prescription medications, check them against the interaction tool on this page before using this product — and talk with your doctor or pharmacist first, especially if you have liver disease or take warfarin, tacrolimus, lithium, or acid-reducing drugs.

This product isn't recommended during pregnancy or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 21, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Digestive Stimulation Complex Chocolate Flavor, straight from the product label.

Brand TerraVita
Barcode (UPC) 064435237899
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Feb 21, 2023
DSLD ID 284098
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Digestive Stimulation Complex Chocolate Flavor by TerraVita, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
25 Drop(s)
Maximum serving Sizes:
40 Drop(s)
Servings per container
227
UPC/BARCODE
064435237899
IngredientAmount% DV
Proprietary Blend0.13 mL--
Birch Glycerite Liquid Extract0 NP--
Boldo Glycerite Liquid Extract0 NP--
Prickly Ash Tree Glycerite Liquid Extract0 NP--

Other ingredients: Glycerin, Chocolate flavor

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Copyright 2018 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Formula

Glycerite liquid extract (1:5)

Formulation

Alcohol free

Suggested/Recommended/Usage/Directions

Suggested Use: Take 25-40 drops of extract in a small amount of warm water 3-4 times daily. Shake well before using.

Precautions

Keep away from children.

Do not use if safety seal around cap is broken or missing.

See for yourself

Digestive Stimulation Complex Chocolate Flavor by TerraVita label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Digestive Stimulation Complex Chocolate Flavor by TerraVita

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size25 Drop(s) Dosage formLiquid Servings per container227 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Other (inactive) ingredients: Glycerin, Chocolate flavor. These complete the product’s ingredient list but are not active constituents.

Interaction report

Digestive Stimulation Complex Chocolate Flavor by TerraVita Drug Interactions

Want to check YOUR meds against Digestive Stimulation Complex Chocolate Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
578Drugs
482 Moderate 96 Minor

Each ingredient & the kinds of drugs it affects

For each ingredient in Digestive Stimulation Complex Chocolate Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Boldo Glycerite Liquid Extract5 drug types · 482 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking boldo with anticoagulant/antiplatelet drugs might increase the risk of bleeding.
Animal and in vitro research shows that boldine, a constituent of boldo, has antiplatelet activity. In one case report, an adult taking a combination of boldo and fenugreek with warfarin experienced an increase in international normalized ratio (INR); however, it is unclear if this effect was due to boldo, fenugreek, the combination, or another factor.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Boldo leaf contains ascaridole, a known liver toxin. Many cases of hepatotoxicity, including elevated liver transaminase levels and jaundice, have been reported in patients taking boldo.

Likelihood Possible Evidence D
Lithium

Theoretically, taking boldo with lithium might increase the levels and clinical effects of lithium.
Boldo is believed to have diuretic effects. Theoretically, these diuretic effects might reduce the excretion of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Tacrolimus (Prograf)

Taking boldo with tacrolimus may decrease the levels and clinical effects of tacrolimus, potentially increasing the risk of transplant rejection.
In one case report, a patient with a long-term history of stable tacrolimus levels developed subtherapeutic levels after taking boldo 300 mg twice daily orally for several weeks. Tacrolimus levels returned to normal after discontinuing boldo. However, the mechanism of this interaction is unclear.

Likelihood Possible Evidence D
Warfarin (Coumadin)

A combination of boldo and fenugreek was thought to be associated with an increased international normalized ratio (INR) in a female on warfarin. It is not clear if boldo, fenugreek, or the combination played a role in this interaction. Therefore, boldo may have additive effects with warfarin.

Likelihood Possible Evidence D

Birch Glycerite Liquid Extract1 drug type · 75 drugs

Diuretic Drugs

Theoretically, birch might interfere with diuretic therapy.

Likelihood Possible Evidence D

Prickly Ash Tree Glycerite Liquid Extract3 drug types · 36 drugs

Antacids

Theoretically, northern prickly ash might decrease the effectiveness of antacids.
There are reports that northern prickly ash increases stomach acid.

Likelihood Possible Evidence D
H2-Blockers

Theoretically, northern prickly ash might decrease the effectiveness of H2-blockers.
There are reports that northern prickly ash increases stomach acid.

Likelihood Possible Evidence D
Proton Pump Inhibitors (Ppis)

Theoretically, northern prickly ash might decrease the effectiveness of PPIs.
There are reports that northern prickly ash increases stomach acid.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Digestive Stimulation Complex Chocolate Flavor, from the product label.

TerraVita

See all TerraVita products
Name
ZooScape LLC
Phone Number
844-449-0444
Web Address
www.ZooScape.com
Pharmacist Counseling Corner

Digestive Stimulation Complex Chocolate Flavor by TerraVita: Common Questions

Does Digestive Stimulation Complex Chocolate Flavor by TerraVita interact with any medications?
Yes. Based on its ingredients, Digestive Stimulation Complex Chocolate Flavor has a known interaction with 578 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Digestive Stimulation Complex Chocolate Flavor contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or nursing?
No — none of these ingredients have enough safety data for pregnancy or breastfeeding, and boldo is considered unsafe because it may stimulate the uterus. Talk with your doctor or pharmacist about safe options during pregnancy and lactation.
What are the side effects I should watch for?
Boldo can cause abdominal pain, nausea, and vomiting at medicinal doses. Birch may trigger allergic reactions if you're sensitive to birch pollen. Rare but serious: boldo has been linked to liver damage (hepatotoxicity) in case reports, so watch for yellowing of the skin or eyes, dark urine, or unusual fatigue.
Does this actually help with digestion?
The evidence we hold doesn't establish that birch, boldo, or prickly ash work for digestive complaints. All three carry insufficient reliable evidence ratings. If you're having digestive trouble, ask your doctor or pharmacist what's actually proven to help.
Is boldo safe to take long-term?
The safety data suggests boldo should be used short-term and in low doses only, because ascaridole — a liver toxin in the leaf — can cause hepatotoxicity with prolonged use. Cases of elevated liver enzymes and jaundice have been reported.
What is prickly ash supposed to do?
Prickly ash is included in this product for digestive support. However, we have no effectiveness ratings for it in our data, and its safety profile is limited — it's best used short-term only.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Digestive Stimulation Complex Chocolate Flavor is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Digestive Stimulation Complex Chocolate Flavor label
Sources

Sources & How We Checked

Digestive Stimulation Complex Chocolate Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Birch 4 references
  1. Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
  2. Lahti, A. and Hannuksela, M. Immediate contact allergy to birch leaves and sap. Contact Dermatitis 1980;6(7):464-465. PubMed
  3. Allam JP, Wuestenberg E, Wolf H, et al. Immunologic response and safety in birch pollen sublingual versus oral vestibule immunotherapy: a pilot study. J Allergy Clin Immunol. 2014;133(6):1757-9.e3. PubMed
  4. Meyer-Hoffert U, Brasch J. Allergic contact dermatitis caused by betulin-containing triterpene extract from the outer bark of birch (Betula alba). Contact Dermatitis. 2013;68(6):382-3.

See these in context on the Birch monograph →

Boldo 10 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Lambert J, Cormier J. Potential interaction between warfarin and boldo-fenugreek. Pharmacotherapy 2001;21:509-12. PubMed
  3. Piscaglia F, Leoni S, Venturi A, et al. Caution in the use of boldo in herbal laxatives: a case of hepatotoxicity. Scand J Gastroenterol 2005;40:236-9. PubMed
  4. Agarwal SC, Crook JR, Pepper CB. Herbal remedies -- how safe are they? A case report of polymorphic ventricular tachycardia/ventricular fibrillation induced by herbal medication used for obesity. Int J Cardiol 2006;106:260-1. PubMed
  5. Teng, C. M., Hsueh, C. M., Chang, Y. L., Ko, F. N., Lee, S. S., and Liu, K. C. Antiplatelet effects of some aporphine and phenanthrene alkaloids in rabbits and man. J Pharm Pharmacol 1997;49(7):706-711. PubMed
  6. Carbajal R, Yisfalem A, Pradhan N, et al. Case report: Boldo (Peumus boldus) and tacrolimus interaction in a renal transplant patient. Transplant Proc 2014;46(7):2400-2. PubMed
  7. Almeida ER, Melo AM, Xavier H. Toxicological evaluation of the hydro-alcohol extract of the dry leaves of Peumus boldus and boldine in rats. Phytother Res 2000;14(2):99-102. DOI
  8. Ribeiro RJ, Silvestre C, Duarte C. Hidden risks of alternative medicines: a case of boldo-induced hepatotoxicity. J Diet Suppl 2017;14(2):186-90. PubMed
  9. Oliveira Sá A, Pimentel T, Oliveira N. Boldo-Induced Hepatotoxicity: A Case of Unexplained Jaundice. Eur J Case Rep Intern Med 2020;7(12):002116. PubMed
  10. Valdes R, Feuereisen A, Bellinghausen M. Allergic Contact Dermatitis to Boldo. Dermatitis 2021;32(2):e31-e32. PubMed

See these in context on the Boldo monograph →

Northern Prickly Ash 2 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

See these in context on the Northern Prickly Ash monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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