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Dietary supplement

Don Quai 530 mg Ingredients & Drug Interactions

by Wonder Laboratories

Don Quai 530 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Don Quai 530 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Don Quai 530 mg is a dietary supplement by Wonder Laboratories with 1 active ingredient. Its ingredients are commonly taken for menopause symptoms, menstrual cramps and irregular periods, premenstrual syndrome (pms).Based on those ingredients, 163 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Dong Quai extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Don Quai 530 mg by Wonder Laboratories

Ask about any prescription or over-the-counter medication and we check it for interactions with Don Quai 530 mg by Wonder Laboratories — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Don Quai 530 mg by Wonder Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: dong quai extract at 530 mg per capsule. Dong quai is a plant used traditionally in Chinese herbal medicine.

The capsule itself is made from gelatin and vegetable cellulose, with silica and vegetable magnesium stearate as inactive ingredients to help with manufacturing and stability.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Dong Quai product and its label doesn't state a use — see Dong Quai's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for dong quai's effectiveness isn't well-established in our data. The conditions it's been studied for — iron deficiency anemia, osteoporosis, coronary heart disease, migraine headache, and atopic dermatitis (eczema) — all have insufficient reliable evidence to rate whether it actually works.

If you're considering it for one of these, talk with your doctor about whether the research supports it for your situation.

The evidence, ingredient by ingredient Dong Quai

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Dong quai is generally well tolerated when taken by mouth, though a small number of people report burping and flatulence. It can increase your bleeding risk and cause sun sensitivity, so be careful with sun exposure.

During pregnancy, the safety data advises against use because dong quai may stimulate the uterus and affect bleeding. There isn't enough safety information to know either way while breastfeeding — talk with your doctor or pharmacist for personalized advice.

Rarely, occupational exposure has triggered allergic asthma and rhinitis. Dong quai contains compounds that are carcinogenic, though it's unknown whether the amounts in this product are high enough to matter with long-term or high-dose use.

Side effects, ingredient by ingredient Dong Quai

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Dong Quai.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 163 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Stop and check with your pharmacist or doctor before taking this if you use warfarin or any other blood thinner (anticoagulant) — the Major-severity bleeding risk is serious. Also double-check if you take antiplatelet drugs (like aspirin used for heart protection), hormone replacement therapy, or any estrogen-based birth control.

These Moderate-severity interactions can reduce hormone effectiveness or raise bleeding risk.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Don Quai is worth considering only if you've talked with your doctor about its unproven effectiveness for your specific condition. It's not suitable if you take blood thinners, antiplatelet drugs, or hormone therapy — the bleeding and hormone-interaction risks are real.

Even if you don't take those drugs, check your full medication list with your pharmacist before starting, and let them know if you're pregnant, breastfeeding, or planning to be.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 19, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Don Quai 530 mg, straight from the product label.

Brand Wonder Laboratories
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Nov 19, 2021
DSLD ID 260529
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Kosher, Adult Female (18 - 50 Years), Menopause, Seniors/Mature (>50 Years) - Women ONLY, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Don Quai 530 mg by Wonder Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
100
IngredientAmount% DV
Dong Quai extract530 mg--

Other ingredients: k-Gelatin, Vegetable Cellulose, Silica, Vegetable Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Tamper evident: Do not use this product if imprinted foil seal under cap is broken or missing.

Keep out of reach of children.

Caution: If you are pregnant or nursing, consult your physician before taking this product.

Formulation

Mfg. in an FDA Registered Facility, using Good Manufacturing Practices (GMPs)

Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.

Contains no artificial color, flavor, sweetener, preservatives, sugar, milk, lactose, soy, wheat, yeast and is sodium free.

Nutritional support during menopause

Gluten free

Made in USA

Storage

Keep tightly closed. Store at room temperature: 59 degrees - 86 degrees F (15 degrees to 30 degrees C).

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Formula 995

FDA Statement of Identity

Dietary Supplement

Formula

Ko Kosher Service

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 1 to 3 capsules three times daily with a large glass of water.

Seals/Symbols

Ko Kosher Service

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Don Quai 530 mg by Wonder Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Don Quai 530 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Don Quai 530 mg by Wonder Laboratories

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Dong Quai extract

Interacts with
163 drugs
530 mg per serving

Dong Quai is a traditional Chinese herb often called "female ginseng" and is mostly used for menstrual and menopausal complaints. High-quality scienti...

Dong Quai extract monograph & interactions

Other (inactive) ingredients: K-Gelatin, Vegetable Cellulose, Silica, Vegetable Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Don Quai 530 mg by Wonder Laboratories Drug Interactions

Want to check YOUR meds against Don Quai 530 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
163Drugs
2 Major 161 Moderate

Ingredients driving the most interactions

Dong Quai extract 163

Individual Drug Interactions

The ingredients in Don Quai 530 mg interact with 163 drugs. Click any drug to see the details.

1 of the 1 ingredient in Don Quai 530 mg interact with drugs. Each result below shows which ingredient is responsible. Dong Quai extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Don Quai 530 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Dong Quai extract3 drug types · 163 drugs

Warfarin (Coumadin)

Dong quai may increase the risk of bleeding when used with warfarin.
Case reports suggest that concomitant use of dong quai with warfarin can increase the anticoagulant effects of warfarin and increase the risk of bleeding. In one case, after 4 weeks of taking dong quai 565 mg once or twice daily, the international normalized ratio (INR) increased to 4.9. The INR normalized 4 weeks after discontinuation of dong quai.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Animal studies suggest that dong quai has antithrombin activity and inhibits platelet aggregation due to its coumarin components. Additionally, some case reports in humans suggest that dong quai can increase the anticoagulant effects of warfarin. However, clinical research in healthy adults shows that taking 1 gram of dong quai root daily for 3 weeks does not significantly inhibit platelet aggregation or cause bleeding. Until more is known, use dong quai with caution in patients taking antiplatelet/anticoagulant drugs.

Likelihood Possible Evidence D
Estrogens

Theoretically, dong quai may reduce the effects of estrogens.
Dong quai has estrogenic effects. Theoretically, concomitant use of large amounts of dong quai might interfere with hormone replacement therapy due to competition for estrogen receptors.

Likelihood Possible Evidence D
Dong Quai extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Don Quai 530 mg, from the product label.

Wonder Laboratories

See all Wonder Laboratories products
Name
Wonder Laboratories
Street Address
115 S.C.T. Ct.
City
White House
State
TN
ZipCode
37188
Pharmacist Counseling Corner

Don Quai 530 mg by Wonder Laboratories: Common Questions

Does Don Quai 530 mg by Wonder Laboratories interact with any medications?
Yes. Based on its ingredients, Don Quai 530 mg has a known interaction with 163 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Don Quai 530 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will Don Quai thin my blood?
Animal studies suggest dong quai can thin your blood by inhibiting platelet clumping and having anticoagulant activity. The bigger concern is taking it alongside blood thinners or antiplatelet drugs — it may push those effects too far and raise your bleeding risk. Don't use it if you take warfarin or similar medications without clearing it first with your pharmacist or doctor.
Can I take this if I'm on hormone replacement therapy?
Probably not without checking first. Dong quai has estrogen-like effects and might interfere with your hormone therapy by competing for the same receptors, potentially making your hormones less effective. Talk with your doctor or pharmacist before combining them.
Is it safe to take during pregnancy?
No. The safety data advises against use during pregnancy because dong quai may stimulate the uterus and affect bleeding. If you're pregnant or planning to be, avoid this product.
What are the common side effects?
When taken by mouth, dong quai is generally well tolerated. The most common side effects reported are burping and flatulence. It can also make your skin more sensitive to sunlight, so be careful with sun exposure.
Does it actually work for iron deficiency anemia or the other conditions listed?
The evidence isn't established in our data. Iron deficiency anemia, osteoporosis, heart disease, migraines, and eczema all show insufficient reliable evidence to rate whether dong quai actually helps. Talk with your doctor about whether research supports it for what you're dealing with.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Don Quai 530 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Don Quai 530 mg label
Go deeper

The Full Monographs Behind Don Quai 530 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Dong Quai

Interacts with 163 drugs

Dong Quai is a traditional Chinese herb often called "female ginseng" and is mostly used for menstrual and menopausal complaints. High-quality scientific evidence that it works for these use...

Read the full Dong Quai monograph →
Sources

Sources & How We Checked

Don Quai 530 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 19 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Dong Quai 19 references
  1. Hirata JD, Swiersz LM, Zell B, et al. Does dong quai have estrogenic effects in postmenopausal women? A double-blind, placebo-controlled trial. Fertil Steril 1997;68:981-6. PubMed
  2. Page RL II, Lawrence JD. Potentiation of warfarin by dong quai. Pharmacotherapy 1999;19:870-6. PubMed
  3. Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
  4. Eagon PK, Elm MS, Hunter DS, et al. Medicinal herbs: modulation of estrogen action. Era of Hope Mtg, Dept Defense; Breast Cancer Res Prog, Atlanta, GA 2000;Jun 8-11.
  5. Dr. Duke's Phytochemical and Ethnobotanical Databases. Available at: http://www.ars-grin.gov/duke/.
  6. Amato P, Christophe S, Mellon PL. Estrogenic activity of herbs commonly used as remedies for menopausal symptoms. Menopause 2002;9:145-50. PubMed
  7. Shi M, Chang L, He G. [Stimulating action of Carthamus tinctorius L., Angelica sinensis (Oliv.) Diels and Leonurus sibiricus L. on the uterus]. Zhongguo Zhong Yao Za Zhi 1995;20:173-5, 192.
  8. Hoult JR, Paya M. Pharmacological and biochemical actions of simple coumarins: natural products with therapeutic potential. Gen Pharmacol 1996;27:713-22.. PubMed
  9. Cheong JL, Bucknall R. Retinal vein thrombosis associated with a herbal phytoestrogen preparation in a susceptible patient. Postgrad Med J 2005;81:266-7.. PubMed
  10. Chang CJ, Chiu JH, Tseng LM, et al. Modulation of HER2 expression by ferulic acid on human breast cancer MCF7 cells. Eur J Clin Invest 2006;36:588-96. PubMed
  11. Chuang CH, Doyle P, Wang JD, et al. Herbal medicines used during the first trimester and major congenital malformations: an analysis of data from a pregnancy cohort study. Drug Saf 2006;29:537-48. PubMed
  12. Lau CBS, Ho TCY, Chan TWL, Kim SCF. Use of dong quai (Angelica sinensis) to treat peri- and postmenopausal symptoms in women with breast cancer: is it appropriate? Menopause 2005;12:734-40.
  13. Ellis GR, Stephens MR. Untitled (photograph and a brief case report). BMJ 1999;319:650.
  14. Nambiar, S., Schwartz, R. H., and Constantino, A. Hypertension in mother and baby linked to ingestion of Chinese herbal medicine. West J Med 1999;171(3):152.
  15. Lee, S. K., Cho, H. K., Cho, S. H., Kim, S. S., Nahm, D. H., and Park, H. S. Occupational asthma and rhinitis caused by multiple herbal agents in a pharmacist. Ann.Allergy Asthma Immunol. 2001;86(4):469-474. PubMed
  16. Xu, J. and Li, G. [Observation on short-term effects of Angelica injection on chronic obstructive pulmonary disease patients with pulmonary hypertension]. Zhongguo Zhong Xi Yi Jie He Za Zhi 2000;20(3):187-189.
  17. Scott, G. N. and Elmer, G. W. Update on natural product--drug interactions. Am J Health Syst.Pharm 2-15-2002;59(4):339-347. PubMed
  18. Circosta, C., Pasquale, R. D., Palumbo, D. R., Samperi, S., and Occhiuto, F. Estrogenic activity of standardized extract of Angelica sinensis. Phytother.Res. 2006;20(8):665-669.
  19. Fung FY, Wong WH, Ang SK, et al. A randomized, double-blind, placebo- controlled study on the anti-haemostatic effects of Curcuma longa, Angelica sinensis and Panax ginseng. Phytomedicine. 2017;32:88-96. PubMed

See these in context on the Dong Quai monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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