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Dietary supplement

Dong Quai 530 mg Ingredients & Drug Interactions

by Herbal Secrets

Capsule Category: Botanical
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

Dong Quai 530 mg is a dietary supplement by Herbal Secrets with 1 active ingredient. Its ingredients are commonly taken for menopause symptoms, menstrual cramps and irregular periods, premenstrual syndrome (pms).Based on those ingredients, 163 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Dong Quai. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Dong Quai 530 mg by Herbal Secrets

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Dong Quai at 530 mg per capsule. Dong Quai is the root of Angelica sinensis, a traditional Chinese herb.

The capsule itself is made from gelatin, microcrystalline cellulose (a binder), magnesium stearate (a flow agent), and silicon dioxide — all inactive ingredients that help deliver the herb.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Dong Quai's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Support women's health and balance hormonal levels.
  • We looked for evidence on: Menopausal symptoms, Premenstrual syndrome (PMS), Dysmenorrhea, Hormonal balance, Menstrual cycle support.
  • The closest evidence on file: Dong Quai is rated "Insufficient Reliable Evidence To Rate" for Menopausal symptoms (Natural Medicines).
  • Also on file: Dong Quai is rated "Insufficient Reliable Evidence To Rate" for Premenstrual syndrome (PMS), Dysmenorrhea.

The evidence for dong quai isn't established in our data. The facts we hold show insufficient reliable evidence to rate it for iron deficiency anemia, osteoporosis, coronary heart disease, migraine headache, or atopic dermatitis (eczema).

That doesn't mean it doesn't work — it means the research so far hasn't been strong enough to be sure. If you're thinking about using it for one of these conditions, talk it over with your doctor or pharmacist about what the current evidence shows and whether it's right for you.

The evidence, ingredient by ingredient Dong Quai

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Dong quai is generally well tolerated when taken by mouth. The most common side effects are burping and flatulence.

Some people have experienced allergic reactions like asthma and rhinitis, especially with occupational exposure. The herb can make your skin more sensitive to sunlight, so use caution if you're out in the sun.

The safety data advises against dong quai during pregnancy — it's rated possibly unsafe because it may stimulate the uterus and affect bleeding. There isn't enough safety information to know whether it's safe while breastfeeding, so it's best avoided.

Additionally, dong quai contains compounds that are carcinogenic, though it's unknown whether the amounts in this product over long-term or high-dose use would be a real concern.

Side effects, ingredient by ingredient Dong Quai

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Dong Quai.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 163 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check with your own doctor or pharmacist if you're on warfarin (Coumadin) — that's a Major interaction. You should also confirm you're not on other blood thinners or antiplatelet drugs (anticoagulants or anticlotting medications), where the interaction is Moderate but still meaningful.

If you're on estrogen-based hormone replacement therapy, check on that too.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.

Dong quai is primarily a concern if you take blood thinners or estrogen-based hormone therapy — check with your own doctor or pharmacist before starting. It's generally well tolerated otherwise, though it can increase sun sensitivity and isn't safe in pregnancy.

The effectiveness evidence isn't established for the conditions it's traditionally used for, so talk it over with your healthcare provider about whether it's the right choice for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Dong Quai 530 mg, straight from the product label.

Brand Herbal Secrets
Barcode (UPC) 810180027175
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Jan 23, 2023
DSLD ID 282824
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Women (not pregnant or lactating), Adult Female (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Dong Quai 530 mg by Herbal Secrets, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
100
UPC/BARCODE
810180027175
IngredientAmount% DV
Dong Quai530 mg--

Other ingredients: Gelatin, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Dong Quai is nicknamed the "female ginseng" because of its benefits for women. Dong Quai supports women's health by helping to balance hormonal levels and relieving symptoms of menopause like hot flashes, cramps, mood swings etc. Cong Quai contains vitamin B12, folic acid, folinic acid, nicotinic acid, and biotin, which helps support blood toning and circulation. Dong Quai's ability to increase circulation and detoxify the blood may help to improve skin complexion, supporting youthful looking skin!

Supports Women's health

Precautions

Caution: Not intended for use by persons under the age of 18, and pregnant or nursing women.

Caution: Not intended for use by persons under the age of 18, and pregnant or nursing women. If you are taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

100% natural

Supports female reproductive health Supports healthy circulation Promotes positive mood & stress relief

Contains No: Artificial color, flavor or sweetener, preservatives, sugar, milk, lactose, soy, gluten, wheat, yeast, fish or sodium.

Seals/Symbols

Made in the USA

GMP Good Manufacturing Practice Quality Product

FDA Statement of Identity

Natural Dietary Supplement

See for yourself

Dong Quai 530 mg by Herbal Secrets label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Dong Quai 530 mg by Herbal Secrets

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Dong Quai

Interacts with
163 drugs
530 mg per serving

Dong Quai is a traditional Chinese herb often called "female ginseng" and is mostly used for menstrual and menopausal complaints. High-quality scienti...

Dong Quai monograph & interactions

Other (inactive) ingredients: Gelatin, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Dong Quai 530 mg by Herbal Secrets Drug Interactions

Want to check YOUR meds against Dong Quai 530 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
163Drugs
2 Major 161 Moderate

Ingredients driving the most interactions

Dong Quai 163

Each ingredient & the kinds of drugs it affects

For each ingredient in Dong Quai 530 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Dong Quai3 drug types · 163 drugs

Warfarin (Coumadin)

Dong quai may increase the risk of bleeding when used with warfarin.
Case reports suggest that concomitant use of dong quai with warfarin can increase the anticoagulant effects of warfarin and increase the risk of bleeding. In one case, after 4 weeks of taking dong quai 565 mg once or twice daily, the international normalized ratio (INR) increased to 4.9. The INR normalized 4 weeks after discontinuation of dong quai.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Animal studies suggest that dong quai has antithrombin activity and inhibits platelet aggregation due to its coumarin components. Additionally, some case reports in humans suggest that dong quai can increase the anticoagulant effects of warfarin. However, clinical research in healthy adults shows that taking 1 gram of dong quai root daily for 3 weeks does not significantly inhibit platelet aggregation or cause bleeding. Until more is known, use dong quai with caution in patients taking antiplatelet/anticoagulant drugs.

Likelihood Possible Evidence D
Estrogens

Theoretically, dong quai may reduce the effects of estrogens.
Dong quai has estrogenic effects. Theoretically, concomitant use of large amounts of dong quai might interfere with hormone replacement therapy due to competition for estrogen receptors.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Dong Quai 530 mg, from the product label.

Herbal Secrets

See all Herbal Secrets products
Name
Herbal Secrets
Street Address
629 Grove Street
City
Jersey City
State
NJ
ZipCode
07310
Web Address
amazingnutrition.com
Pharmacist Counseling Corner

Dong Quai 530 mg by Herbal Secrets: Common Questions

Does Dong Quai 530 mg by Herbal Secrets interact with any medications?
Yes. Based on its ingredients, Dong Quai 530 mg has a known interaction with 163 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Dong Quai 530 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take dong quai if I'm on warfarin or another blood thinner?
No — not without checking first with your doctor or pharmacist. Dong quai can increase the blood-thinning effects of these medications and raise your bleeding risk, especially warfarin. Case reports show that some people's blood-thinning levels climbed after a few weeks of dong quai. Your healthcare provider needs to know before you start.
What are the most common side effects?
Burping and flatulence are the most common. Dong quai can also make your skin more sensitive to sunlight, so use care if you're out in the sun. Allergic reactions like asthma and rhinitis have been reported in some people, particularly with occupational exposure.
Is dong quai safe during pregnancy?
No — the safety data rates it as possibly unsafe. Dong quai may stimulate the uterus and affect bleeding, so it's best avoided during pregnancy. Talk with your doctor or pharmacist if you're pregnant or planning to become pregnant.
Is it safe to breastfeed while taking dong quai?
There isn't enough safety information to know. It's best avoided while breastfeeding until more is known. Your doctor or pharmacist can discuss whether there are safer alternatives for you.
Will dong quai interfere with my hormone replacement therapy?
It might. Dong quai has estrogenic effects and could theoretically interfere with estrogen-based hormone replacement by competing for estrogen receptors. Check with your doctor or pharmacist before taking it alongside hormone therapy.
Does the science support using dong quai for anemia, osteoporosis, or migraines?
The evidence isn't established yet. We don't have reliable evidence to rate dong quai for iron deficiency anemia, osteoporosis, coronary heart disease, migraines, or eczema. Ask your doctor whether dong quai makes sense for your situation or what else might help.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Dong Quai 530 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Dong Quai 530 mg label
Sources

Sources & How We Checked

Dong Quai 530 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 19 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Dong Quai 19 references
  1. Hirata JD, Swiersz LM, Zell B, et al. Does dong quai have estrogenic effects in postmenopausal women? A double-blind, placebo-controlled trial. Fertil Steril 1997;68:981-6. PubMed
  2. Page RL II, Lawrence JD. Potentiation of warfarin by dong quai. Pharmacotherapy 1999;19:870-6. PubMed
  3. Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
  4. Eagon PK, Elm MS, Hunter DS, et al. Medicinal herbs: modulation of estrogen action. Era of Hope Mtg, Dept Defense; Breast Cancer Res Prog, Atlanta, GA 2000;Jun 8-11.
  5. Dr. Duke's Phytochemical and Ethnobotanical Databases. Available at: http://www.ars-grin.gov/duke/.
  6. Amato P, Christophe S, Mellon PL. Estrogenic activity of herbs commonly used as remedies for menopausal symptoms. Menopause 2002;9:145-50. PubMed
  7. Shi M, Chang L, He G. [Stimulating action of Carthamus tinctorius L., Angelica sinensis (Oliv.) Diels and Leonurus sibiricus L. on the uterus]. Zhongguo Zhong Yao Za Zhi 1995;20:173-5, 192.
  8. Hoult JR, Paya M. Pharmacological and biochemical actions of simple coumarins: natural products with therapeutic potential. Gen Pharmacol 1996;27:713-22.. PubMed
  9. Cheong JL, Bucknall R. Retinal vein thrombosis associated with a herbal phytoestrogen preparation in a susceptible patient. Postgrad Med J 2005;81:266-7.. PubMed
  10. Chang CJ, Chiu JH, Tseng LM, et al. Modulation of HER2 expression by ferulic acid on human breast cancer MCF7 cells. Eur J Clin Invest 2006;36:588-96. PubMed
  11. Chuang CH, Doyle P, Wang JD, et al. Herbal medicines used during the first trimester and major congenital malformations: an analysis of data from a pregnancy cohort study. Drug Saf 2006;29:537-48. PubMed
  12. Lau CBS, Ho TCY, Chan TWL, Kim SCF. Use of dong quai (Angelica sinensis) to treat peri- and postmenopausal symptoms in women with breast cancer: is it appropriate? Menopause 2005;12:734-40.
  13. Ellis GR, Stephens MR. Untitled (photograph and a brief case report). BMJ 1999;319:650.
  14. Nambiar, S., Schwartz, R. H., and Constantino, A. Hypertension in mother and baby linked to ingestion of Chinese herbal medicine. West J Med 1999;171(3):152.
  15. Lee, S. K., Cho, H. K., Cho, S. H., Kim, S. S., Nahm, D. H., and Park, H. S. Occupational asthma and rhinitis caused by multiple herbal agents in a pharmacist. Ann.Allergy Asthma Immunol. 2001;86(4):469-474. PubMed
  16. Xu, J. and Li, G. [Observation on short-term effects of Angelica injection on chronic obstructive pulmonary disease patients with pulmonary hypertension]. Zhongguo Zhong Xi Yi Jie He Za Zhi 2000;20(3):187-189.
  17. Scott, G. N. and Elmer, G. W. Update on natural product--drug interactions. Am J Health Syst.Pharm 2-15-2002;59(4):339-347. PubMed
  18. Circosta, C., Pasquale, R. D., Palumbo, D. R., Samperi, S., and Occhiuto, F. Estrogenic activity of standardized extract of Angelica sinensis. Phytother.Res. 2006;20(8):665-669.
  19. Fung FY, Wong WH, Ang SK, et al. A randomized, double-blind, placebo- controlled study on the anti-haemostatic effects of Curcuma longa, Angelica sinensis and Panax ginseng. Phytomedicine. 2017;32:88-96. PubMed

See these in context on the Dong Quai monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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