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Dietary supplement

Dong Quai 550 mg Ingredients & Drug Interactions

by Thompson

Capsule Category: Botanical With Nutrients
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

Dong Quai 550 mg is a dietary supplement by Thompson with 1 active ingredient. Its ingredients are commonly taken for menopause symptoms, menstrual cramps and irregular periods, premenstrual syndrome (pms).Based on those ingredients, 163 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Dong Quai. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Dong Quai 550 mg by Thompson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Thompson's Dong Quai 550 mg is a single-ingredient supplement: each capsule holds 550 mg of dong quai root, a traditional plant used in Asian medicine. The capsule itself is made from gelatin.

Dong quai is sometimes called "female ginseng" because it's been used historically for women's health, though the clinical evidence for most of those uses is still being built.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Dong Quai product and its label doesn't state a use — see Dong Quai's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The data we hold shows insufficient evidence to rate dong quai for iron deficiency anemia, osteoporosis, heart disease, migraine headache, or eczema. That means research hasn't yet established whether it works for these purposes—not that it doesn't, just that the evidence isn't there yet.

If you're considering it for a specific condition, check with your doctor or pharmacist about what the current research actually supports for your situation.

The evidence, ingredient by ingredient Dong Quai

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Dong quai is generally well tolerated when taken by mouth. The most common side effects are burping and flatulence.

It can cause skin sensitivity to sunlight, so if you use it, be cautious about sun exposure. Dong quai is rated Possibly Unsafe in pregnancy because it may stimulate the uterus and affect bleeding.

There isn't enough safety data to know if it's okay while breastfeeding, so it's best avoided during lactation. Dong quai also contains some compounds that are known carcinogens, though it's unclear whether the amount in a supplement dose is high enough to be a real concern with long-term or high-dose use.

If you're pregnant, planning to become pregnant, or breastfeeding, talk with your doctor or pharmacist before using this product.

Side effects, ingredient by ingredient Dong Quai

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Dong Quai.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 163 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you're on warfarin (Coumadin) or any other blood thinner or antiplatelet drug like aspirin or clopidogrel—the risk of bleeding goes up. Also mention it if you take estrogen-based medications such as birth control pills or hormone replacement therapy, as dong quai may weaken their effect.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This supplement is mainly a concern if you take blood thinners (especially warfarin), other anticoagulants, or hormone-based medications like birth control or HRT—serious drug interactions are documented. Dong quai is rated Possibly Unsafe in pregnancy and best avoided while breastfeeding.

Before you start, check your medications with your doctor or pharmacist to make sure it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 26, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Dong Quai 550 mg, straight from the product label.

Brand Thompson
Barcode (UPC) 031315190926
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Aug 26, 2014
DSLD ID 36475
Product type Botanical With Nutrients
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Women (not pregnant or lactating), Adult Female (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Dong Quai 550 mg by Thompson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
031315190926
IngredientAmount% DV
Total Carbohydrates1 Gram(s)1%
Dong Quai1.1 Gram(s)--

Other ingredients: Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Keep out of reach of children.

Do not take if pregnant or lactating.

WARNING: Do not use if safety seal is broken or missing.

General Statements

Keep your licensed health care practitioner informed when using this product.

SINCE 1932

FEMALE SUPPORT

FRESH HEALTHY

ONCE DAILY

Suggested/Recommended/Usage/Directions

Directions: Use only as directed. Take two capsules one to two times daily with meal or glass of water.

Storage

Store in cool, dry place.

Brand IP Statement(s)

Our own laboratory analysis guarantees purity and freshness of all Thompson(R) products.

(C)2007

General

9120566 1007

FDA Statement of Identity

DIETARY SUPPLEMENT

See for yourself

Dong Quai 550 mg by Thompson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Dong Quai 550 mg by Thompson

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Dong Quai

Interacts with
163 drugs
1.1 Gram(s) per serving

Dong Quai is a traditional Chinese herb often called "female ginseng" and is mostly used for menstrual and menopausal complaints. High-quality scienti...

Dong Quai monograph & interactions

Other (inactive) ingredients: Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Dong Quai 550 mg by Thompson Drug Interactions

Want to check YOUR meds against Dong Quai 550 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
163Drugs
2 Major 161 Moderate

Ingredients driving the most interactions

Dong Quai 163

Each ingredient & the kinds of drugs it affects

For each ingredient in Dong Quai 550 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Dong Quai3 drug types · 163 drugs

Warfarin (Coumadin)

Dong quai may increase the risk of bleeding when used with warfarin.
Case reports suggest that concomitant use of dong quai with warfarin can increase the anticoagulant effects of warfarin and increase the risk of bleeding. In one case, after 4 weeks of taking dong quai 565 mg once or twice daily, the international normalized ratio (INR) increased to 4.9. The INR normalized 4 weeks after discontinuation of dong quai.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Animal studies suggest that dong quai has antithrombin activity and inhibits platelet aggregation due to its coumarin components. Additionally, some case reports in humans suggest that dong quai can increase the anticoagulant effects of warfarin. However, clinical research in healthy adults shows that taking 1 gram of dong quai root daily for 3 weeks does not significantly inhibit platelet aggregation or cause bleeding. Until more is known, use dong quai with caution in patients taking antiplatelet/anticoagulant drugs.

Likelihood Possible Evidence D
Estrogens

Theoretically, dong quai may reduce the effects of estrogens.
Dong quai has estrogenic effects. Theoretically, concomitant use of large amounts of dong quai might interfere with hormone replacement therapy due to competition for estrogen receptors.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Dong Quai 550 mg, from the product label.

Thompson

See all Thompson products
Name
Nutraceutical Corp.
Web Address
www.nutraceutical.com
Pharmacist Counseling Corner

Dong Quai 550 mg by Thompson: Common Questions

Does Dong Quai 550 mg by Thompson interact with any medications?
Yes. Based on its ingredients, Dong Quai 550 mg has a known interaction with 163 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Dong Quai 550 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is dong quai safe to use with warfarin or other blood thinners?
No—it's a major interaction. Dong quai can boost how much your blood thinner works, raising your bleeding risk. Case reports show it can happen within a few weeks. If you take warfarin or any anticoagulant, you must talk with your doctor or pharmacist before starting dong quai.
Can I take this if I'm on birth control or hormone replacement therapy?
Possibly not without checking first. Dong quai has estrogenic effects and may interfere with how well these medications work by competing for estrogen receptors. Ask your doctor or pharmacist before combining them.
Is it safe during pregnancy or breastfeeding?
During pregnancy, it's rated Possibly Unsafe because it may stimulate the uterus and affect bleeding—avoid it. While breastfeeding, there's not enough safety data, so it's best to skip it too. Talk with your doctor or pharmacist for personalized advice.
What are the common side effects?
Burping and flatulence are the most common. Dong quai can also make your skin more sensitive to sunlight, so be careful about sun exposure if you use it.
Does dong quai actually work for what it's marketed for?
The data we hold shows insufficient evidence to rate it for iron deficiency, osteoporosis, heart disease, migraine, or eczema. That means research hasn't yet proven it works for these—ask your doctor what the science really supports for your situation.
What exactly is dong quai?
It's a plant root used in traditional Asian medicine, sometimes called "female ginseng" because of its history in women's health. Each capsule here contains 550 mg of the root powder.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Dong Quai 550 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Dong Quai 550 mg label
Sources

Sources & How We Checked

Dong Quai 550 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 19 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Dong Quai 19 references
  1. Hirata JD, Swiersz LM, Zell B, et al. Does dong quai have estrogenic effects in postmenopausal women? A double-blind, placebo-controlled trial. Fertil Steril 1997;68:981-6. PubMed
  2. Page RL II, Lawrence JD. Potentiation of warfarin by dong quai. Pharmacotherapy 1999;19:870-6. PubMed
  3. Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
  4. Eagon PK, Elm MS, Hunter DS, et al. Medicinal herbs: modulation of estrogen action. Era of Hope Mtg, Dept Defense; Breast Cancer Res Prog, Atlanta, GA 2000;Jun 8-11.
  5. Dr. Duke's Phytochemical and Ethnobotanical Databases. Available at: http://www.ars-grin.gov/duke/.
  6. Amato P, Christophe S, Mellon PL. Estrogenic activity of herbs commonly used as remedies for menopausal symptoms. Menopause 2002;9:145-50. PubMed
  7. Shi M, Chang L, He G. [Stimulating action of Carthamus tinctorius L., Angelica sinensis (Oliv.) Diels and Leonurus sibiricus L. on the uterus]. Zhongguo Zhong Yao Za Zhi 1995;20:173-5, 192.
  8. Hoult JR, Paya M. Pharmacological and biochemical actions of simple coumarins: natural products with therapeutic potential. Gen Pharmacol 1996;27:713-22.. PubMed
  9. Cheong JL, Bucknall R. Retinal vein thrombosis associated with a herbal phytoestrogen preparation in a susceptible patient. Postgrad Med J 2005;81:266-7.. PubMed
  10. Chang CJ, Chiu JH, Tseng LM, et al. Modulation of HER2 expression by ferulic acid on human breast cancer MCF7 cells. Eur J Clin Invest 2006;36:588-96. PubMed
  11. Chuang CH, Doyle P, Wang JD, et al. Herbal medicines used during the first trimester and major congenital malformations: an analysis of data from a pregnancy cohort study. Drug Saf 2006;29:537-48. PubMed
  12. Lau CBS, Ho TCY, Chan TWL, Kim SCF. Use of dong quai (Angelica sinensis) to treat peri- and postmenopausal symptoms in women with breast cancer: is it appropriate? Menopause 2005;12:734-40.
  13. Ellis GR, Stephens MR. Untitled (photograph and a brief case report). BMJ 1999;319:650.
  14. Nambiar, S., Schwartz, R. H., and Constantino, A. Hypertension in mother and baby linked to ingestion of Chinese herbal medicine. West J Med 1999;171(3):152.
  15. Lee, S. K., Cho, H. K., Cho, S. H., Kim, S. S., Nahm, D. H., and Park, H. S. Occupational asthma and rhinitis caused by multiple herbal agents in a pharmacist. Ann.Allergy Asthma Immunol. 2001;86(4):469-474. PubMed
  16. Xu, J. and Li, G. [Observation on short-term effects of Angelica injection on chronic obstructive pulmonary disease patients with pulmonary hypertension]. Zhongguo Zhong Xi Yi Jie He Za Zhi 2000;20(3):187-189.
  17. Scott, G. N. and Elmer, G. W. Update on natural product--drug interactions. Am J Health Syst.Pharm 2-15-2002;59(4):339-347. PubMed
  18. Circosta, C., Pasquale, R. D., Palumbo, D. R., Samperi, S., and Occhiuto, F. Estrogenic activity of standardized extract of Angelica sinensis. Phytother.Res. 2006;20(8):665-669.
  19. Fung FY, Wong WH, Ang SK, et al. A randomized, double-blind, placebo- controlled study on the anti-haemostatic effects of Curcuma longa, Angelica sinensis and Panax ginseng. Phytomedicine. 2017;32:88-96. PubMed

See these in context on the Dong Quai monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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