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Dietary supplement

Double Strength Prosta-Guard Lycopene 10 mg Ingredients & Drug Interactions

by Vitamin World

Double Strength Prosta-Guard Lycopene 10 mg label
See full label image
Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Double Strength Prosta-Guard Lycopene 10 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Double Strength Prosta-Guard Lycopene 10 mg is a dietary supplement by Vitamin World with 1 active ingredient. Its ingredients are commonly taken for heart health, prostate health, antioxidant support.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lycopene. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Double Strength Prosta-Guard Lycopene 10 mg by Vitamin World

Ask about any prescription or over-the-counter medication and we check it for interactions with Double Strength Prosta-Guard Lycopene 10 mg by Vitamin World — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Double Strength Prosta-Guard Lycopene 10 mg by Vitamin World

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: 10 mg of lycopene per softgel capsule. Lycopene is a red pigment found naturally in tomatoes and other red plants; it's also included here as a tomato extract among the inactive ingredients.

The softgel itself is made from gelatin, soybean oil, corn oil, vegetable glycerin, and yellow beeswax.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Prostate health support.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS), Prostate cancer.
  • The strongest evidence on file: Lycopene is rated "Possibly Effective" for Prostate cancer (Natural Medicines).
  • Also on file: Lycopene is rated "Insufficient Reliable Evidence To Rate" for Benign prostatic hyperplasia (BPH), Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS).

Lycopene has been studied most for prostate cancer, where it's rated possibly effective — meaning there's some evidence it may help, but more research is needed to be sure. For bladder cancer, diabetes, and high cholesterol, the evidence is either insufficient to say or points away from benefit.

Data on its use for exercise-induced asthma and ALS is too limited for us to rate.

The evidence, ingredient by ingredient Lycopene

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lycopene from food is considered safe, and supplement doses are generally well tolerated. The most common side effects from the supplement are gastrointestinal — diarrhea, gas, bloating, nausea, vomiting, heartburn, and loss of appetite.

One case of chest pain was reported in a pregnant woman taking a different lycopene product, though whether lycopene caused it is unclear. For pregnancy and breastfeeding, food amounts of lycopene are fine, but supplement safety data is too limited.

Talk with your doctor or pharmacist before taking a lycopene supplement if you're pregnant or nursing.

Side effects, ingredient by ingredient Lycopene

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lycopene.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you're on any blood thinners or antiplatelet drugs — including warfarin, apixaban, dabigatran, rivaroxaban, aspirin, clopidogrel, ticagrelor, or similar medications. Lycopene may increase your bleeding risk when combined with these.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you're interested in lycopene for prostate health and you don't take blood thinners, this is generally well tolerated. If you're on any anticoagulant or antiplatelet drug — whether prescription or over-the-counter — check with your doctor or pharmacist first.

And if you have a sensitive stomach, start low and watch for gas or loose stools.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Double Strength Prosta-Guard Lycopene 10 mg, straight from the product label.

Brand Vitamin World
Barcode (UPC) 074312721113
Net contents 100 Easy to Swallow Rapid Release Softgel(s)
Market status On market
Date entered into DSLD May 24, 2013
DSLD ID 21036
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult Male (18-50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Double Strength Prosta-Guard Lycopene 10 mg by Vitamin World, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
UPC/BARCODE
074312721113
IngredientAmount% DV
Lycopene10 mg--

Other ingredients: Soybean Oil, Gelatin, Corn Oil, Vegetable Glycerin, yellow Beeswax, Tomato Extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

(C)2012 Vitamin World, Inc.

Prosta-Guard(R)

General

PROD. #2111 B2111 07C

General Statements

Get healthy.

This product has been developed, manufactured and packaged by Vitamin World. Our world-class facilities allow us to control exactly what goes into each product. It is your assurance that you are getting the highest quality and freshest products. You have our guarantee!

Lycopene promotes prostate health and supports the cardiovascular system.* Lycopene also promotes heart health.*

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

DIETARY SUPPLEMENT

Formulation

No Artificial Color, Flavor or Sweetener, No Preservatives, No Sugar, No Starch, No Milk, No Lactose, No Gluten, No Wheat, No Yeast, No Fish. Sodium Free.

Precautions

WARNING: If you are pregnant, nursing or taking any medications, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Do not use if seal under cap is broken or missing.

Suggested/Recommended/Usage/Directions

DIRECTIONS: For adults, take one (1) softgel up to four times daily, preferably with meals.

Seals/Symbols

QA QUALITY ASSURED

Storage

Store at room temperature.

Formula

Prostate & Heart Health*

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Double Strength Prosta-Guard Lycopene 10 mg by Vitamin World label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Double Strength Prosta-Guard Lycopene 10 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Double Strength Prosta-Guard Lycopene 10 mg by Vitamin World

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Lycopene

Interacts with
122 drugs
10 mg per serving

Lycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible hear...

Lycopene monograph & interactions

Other (inactive) ingredients: Soybean Oil, Gelatin, Corn Oil, Vegetable Glycerin, Yellow Beeswax, Tomato Extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Double Strength Prosta-Guard Lycopene 10 mg by Vitamin World Drug Interactions

Want to check YOUR meds against Double Strength Prosta-Guard Lycopene 10 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

Lycopene 122

Individual Drug Interactions

The ingredients in Double Strength Prosta-Guard Lycopene 10 mg interact with 122 drugs. Click any drug to see the details.

1 of the 1 ingredient in Double Strength Prosta-Guard Lycopene 10 mg interact with drugs. Each result below shows which ingredient is responsible. Lycopene

Each ingredient & the kinds of drugs it affects

For each ingredient in Double Strength Prosta-Guard Lycopene 10 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lycopene1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
In vitro research shows that lycopene has antiplatelet effects.

Likelihood Possible Evidence D
Lycopene full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Double Strength Prosta-Guard Lycopene 10 mg, from the product label.

Vitamin World

See all Vitamin World products
Name
Vitamin World, Inc.
City
Ronkonkoma
State
NY
ZipCode
11779
Pharmacist Counseling Corner

Double Strength Prosta-Guard Lycopene 10 mg by Vitamin World: Common Questions

Does Double Strength Prosta-Guard Lycopene 10 mg by Vitamin World interact with any medications?
Yes. Based on its ingredients, Double Strength Prosta-Guard Lycopene 10 mg has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Double Strength Prosta-Guard Lycopene 10 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is lycopene and why is it in a prostate supplement?
Lycopene is a red pigment from tomatoes and other red plants. Research suggests it may help with prostate cancer, which is why it's included in prostate-support formulas. You're getting 10 mg per capsule — a dose that's studied in supplements, though food amounts are safe too.
Can I take this if I'm on aspirin?
Not without checking first. Aspirin thins your blood, and lycopene may do the same thing in the lab. Together, they could increase your bleeding risk. Talk to your doctor or pharmacist before combining them.
What side effects might I get?
The most common ones are digestive — diarrhea, gas, bloating, nausea, or heartburn. They tend to be mild, but if they bother you, let your pharmacist know.
Is it safe to take while pregnant or breastfeeding?
Food amounts of lycopene are fine during pregnancy and nursing, but supplement safety data is too limited to say either way. Talk with your doctor or pharmacist for personalized advice if you're pregnant or nursing and considering this product.
Does this actually work for prostate health?
Lycopene is rated possibly effective for prostate cancer based on available research, meaning there's some evidence but we need more studies to be confident. For other prostate concerns, the evidence is weaker or unknown.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Double Strength Prosta-Guard Lycopene 10 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Double Strength Prosta-Guard Lycopene 10 mg label
Go deeper

The Full Monographs Behind Double Strength Prosta-Guard Lycopene 10 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lycopene

Interacts with 122 drugs

Lycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible heart and prostate benefits, but evidence fr...

Read the full Lycopene monograph →
Sources

Sources & How We Checked

Double Strength Prosta-Guard Lycopene 10 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lycopene 10 references
  1. Sharma, J. B., Kumar, A., Kumar, A., Malhotra, M., Arora, R., Prasad, S., and Batra, S. Effect of lycopene on pre-eclampsia and intra-uterine growth retardation in primigravidas. Int J Gynaecol.Obstet. 2003;81(3):257-262. PubMed
  2. Hsiao, G., Wang, Y., Tzu, N. H., Fong, T. H., Shen, M. Y., Lin, K. H., Chou, D. S., and Sheu, J. R. Inhibitory effects of lycopene on in vitro platelet activation and in vivo prevention of thrombus formation. J Lab Clin Med 2005;146(4):216-226. PubMed
  3. Clark, P. E., Hall, M. C., Borden, L. S., Jr., Miller, A. A., Hu, J. J., Lee, W. R., Stindt, D., D'Agostino, R., Jr., Lovato, J., Harmon, M., and Torti, F. M. Phase I-II prospective dose-escalating trial of lycopene in patients with biochemical relapse o
  4. O'Kennedy, N., Crosbie, L., Whelan, S., Luther, V., Horgan, G., Broom, J. I., Webb, D. J., and Duttaroy, A. K. Effects of tomato extract on platelet function: a double-blinded crossover study in healthy humans. Am.J.Clin.Nutr. 2006;84(3):561-569. PubMed
  5. Jatoi, A., Burch, P., Hillman, D., Vanyo, J. M., Dakhil, S., Nikcevich, D., Rowland, K., Morton, R., Flynn, P. J., Young, C., and Tan, W. A tomato-based, lycopene-containing intervention for androgen-independent prostate cancer: results of a Phase II stu
  6. Schwenke, C., Ubrig, B., Thurmann, P., Eggersmann, C., and Roth, S. Lycopene for advanced hormone refractory prostate cancer: a prospective, open phase II pilot study. J.Urol. 2009;181(3):1098-1103. PubMed
  7. Banerjee, S., Jeyaseelan, S., and Guleria, R. Trial of lycopene to prevent pre-eclampsia in healthy primigravidas: results show some adverse effects. J.Obstet.Gynaecol.Res. 2009;35(3):477-482. PubMed
  8. Haseen, F., Cantwell, M. M., O'Sullivan, J. M., and Murray, L. J. Is there a benefit from lycopene supplementation in men with prostate cancer? A systematic review. Prostate Cancer Prostatic.Dis. 2009;12(4):325-332. PubMed
  9. Ilic, D., Forbes, K. M., and Hassed, C. Lycopene for the prevention of prostate cancer. Cochrane.Database.Syst.Rev. 2011;(11):CD008007. PubMed
  10. Sawardekar SB, Patel TC, Uchil D. Comparative evaluation of antiplatelet effect of lycopene with aspirin and the effect of their combination on platelet aggregation: an in vitro study. Indian J Pharmacol 2016;48:26-31. PubMed

See these in context on the Lycopene monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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