No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Dragon's Blood Ingredients & Drug Interactions

by Herb Pharm

Liquid Category: Botanical
No known interaction
The interaction bottom line No known interaction

Dragon's Blood is a dietary supplement by Herb Pharm with 1 active ingredient. Its ingredients are commonly taken for diarrhea, wound healing and skin sores, digestive and stomach complaints.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Dragon's Blood by Herb Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Dragon's Blood tree sap (Croton lechleri), a resin traditionally harvested from trees in South America. The liquid is preserved in certified organic cane alcohol, which is an inactive ingredient.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: gastrointestinal system restoration and health.
  • We looked for evidence on: HIV/AIDS-related diarrhea, Travelers' diarrhea, Irritable bowel syndrome (IBS), Insect bite, Digestive complaints, Wound healing — and 2 related terms.
  • The strongest evidence on file: Sangre De Grado is rated "Possibly Effective" for HIV/AIDS-related diarrhea (Natural Medicines).
  • Also on file: Sangre De Grado is rated "Possibly Effective" for Travelers' diarrhea.
  • Also on file: Sangre De Grado is rated "Possibly Ineffective" for Irritable bowel syndrome (IBS).

The evidence we hold suggests Dragon's Blood tree sap is possibly effective for HIV/AIDS-related diarrhea and travelers' diarrhea. That means there is some research backing its use for these conditions, but the data isn't yet strong enough to call it proven.

If you're considering it for either of these reasons, talk with your pharmacist or doctor about whether it fits your situation.

The evidence, ingredient by ingredient Sangre De Grado

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Dragon's Blood tree sap has a long history of traditional use, but safety data for it as a supplement is limited, so use it cautiously. In clinical studies of a purified form of the ingredient, mild gastrointestinal side effects, bronchitis, and headache have been reported in some participants — no serious adverse effects were seen, and it appears generally well tolerated overall.

During pregnancy, there isn't enough safety information, so the data advises against use. The same applies to breastfeeding — safety is unknown, so it's best to avoid it.

If you're pregnant, planning pregnancy, or breastfeeding, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Sangre De Grado

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for Dragon's Blood tree sap. That doesn't mean none exist, so it's still smart to check your exact medications with the tool on this page.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Dragon's Blood tree sap is worth considering if you're dealing with traveler's diarrhea or diarrhea related to HIV/AIDS and want a traditional botanical option. Skip it if you're pregnant or breastfeeding.

Since safety data is limited overall, talk with your pharmacist before starting, especially if you have ongoing health concerns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Dragon's Blood, straight from the product label.

Brand Herb Pharm
Barcode (UPC) 090700004347
Net contents 4 fl. Oz.; 120 mL
Market status On market
Date entered into DSLD Dec 22, 2019
DSLD ID 209816
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Dragon's Blood by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
0.7 mL
Servings per container
168
UPC/BARCODE
090700004347
IngredientAmount% DV
Dragon's Blood tree sap (Croton lechleri) succus708 mg--

Other ingredients: certified organic Cane Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use Shake well before using Add 1 full squeeze of the dropper bulb to 2 oz. of water or juice, 1 to 3 times per day. Best taken between meals.

Precautions

Caution: Seek expert medical advice before taking during pregnancy or nursing.

Keep out of the reach of children

Storage

Store away from heat & light

Formula

Croton lechleri

Dragon's Blood Succus (Sangre de Drago)

We prepare our Dragon's Blood Succus from responsibly wildcrafted fresh liquid tree sap of Croton lechleri trees from the Amazon rainforest of Peru.

Formulation

System restoration Gastrointestinal

Gluten-free

FDA Statement of Identity

Herbal Supplement

FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Dragon's Blood by Herb Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Dragon's Blood by Herb Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container168 Amounts shown are per serving.

708 mg per serving

Sangre de Grado is a red tree sap from the Amazon rainforest used traditionally for diarrhea, wounds, and skin problems. Some of its compounds have be...

Dragon's Blood tree sap (Croton lechleri) succus monograph & interactions

Other (inactive) ingredients: Certified organic Cane Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Dragon's Blood by Herb Pharm Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Dragon's Blood. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Dragon's Blood, from the product label.

Herb Pharm

See all Herb Pharm products
Name
Herb Pharm
City
Williams
State
OR
ZipCode
97544
Phone Number
800-348-4372
Web Address
www.herb-pharm.com
Pharmacist Counseling Corner

Dragon's Blood by Herb Pharm: Common Questions

Does Dragon's Blood by Herb Pharm interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Dragon's Blood. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Dragon's Blood contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is Dragon's Blood tree sap used for?
The evidence we have suggests it may help with traveler's diarrhea and diarrhea related to HIV/AIDS. It's a traditional remedy from South American trees, but research on it is still limited.
Can I take this while pregnant?
No — there isn't enough safety information during pregnancy, so the safety data advises against it. Talk with your doctor before considering this product if you're pregnant or planning to become pregnant.
Is it safe to breastfeed while taking Dragon's Blood?
Safety while breastfeeding is unknown, so it's best to avoid it. If you're breastfeeding and interested in this product, check with your doctor or pharmacist first.
What side effects have been reported?
In clinical studies of a purified form, mild gastrointestinal side effects, bronchitis, and headache were reported in some people — no serious adverse effects were seen. It appears generally well tolerated overall.
Why is there only one ingredient?
This is a single-herb product designed to deliver Dragon's Blood tree sap in liquid form, preserved with organic cane alcohol.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Dragon's Blood is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Dragon's Blood label
Go deeper

The Full Monographs Behind Dragon's Blood’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Dragon's Blood's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 9 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sangre De Grado 9 references
  1. Holodniy M, Koch J, Mistal M, et al. A double blind, randomized, placebo-controlled phase II study to assess the safety and efficacy of orally administered SP-303 for the symptomatic treatment of diarrhea in patients with AIDS. Am J Gastroenterol 1999;9 PubMed
  2. Safrin S, McKinley G, McKeough M, et al. Treatment of acyclovir-unresponsive cutaneous herpes simplex virus infection with topically applied SP-303. Antiviral Res 1994;25:185-92. PubMed
  3. Orozco-Topete R, Sierra-Madero J, Cano-Dominguez C, et al. Safety and efficacy of Virend for topical treatment of genital and anal herpes simplex lesions in patients with AIDS. Antiviral Res 1997;35:91-103. PubMed
  4. Dicesare D, Dupont HL, Mathewson JJ, et al. A double-blind randomized, placebo-controlled study of SP-303 (Provir) in the symptomatic treatment of acute diarrhea among travelers to Mexico and Jamaica. Infectious Diseases Society of America Annual Meetin
  5. Miller, M. J., Vergnolle, N., McKnight, W., Musah, R. A., Davison, C. A., Trentacosti, A. M., Thompson, J. H., Sandoval, M., and Wallace, J. L. Inhibition of neurogenic inflammation by the Amazonian herbal medicine sangre de grado. J.Invest Dermatol. 200 PubMed
  6. DiCesare, D., DuPont, H. L., Mathewson, J. J., Ashley, D., Martinez-Sandoval, F., Pennington, J. E., and Porter, S. B. A double blind, randomized, placebo-controlled study of SP-303 (Provir) in the symptomatic treatment of acute diarrhea among travelers
  7. MacArthur RD, Hawkins T, Brown SJ, et al. Efficacy and safety of crofelemer for noninfectious diarrhea in HIV-seropositive individuals (ADVENT trial): a randomized, double-blind, placebo-controlled, two-stage study. HIV Clin Trials 2013;14(6):261-73. PubMed
  8. Mangel AW, Chaturvedi P. Evaluation of crofelemer in the treatment of diarrhea-predominant irritable bowel syndrome patients. Digestion 2008;78(4):180-6. PubMed
  9. Nee J, Salley K, Ludwig AG, et al. Randomized clinical trial: crofelemer treatment in women with diarrhea-predominant irritable bowel syndrome. Clin Transl Gastroenterol. 2019;10(12):e00110. PubMed

See these in context on the Sangre De Grado monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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