China Tung Hsueh Pills Ingredients & Drug Interactions
by Plum Flower
What is this page for?
First and foremost: checking China Tung Hsueh Pills against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
China Tung Hsueh Pills is a dietary supplement by Plum Flower with 11 active ingredients. Its ingredients are commonly taken for menopause symptoms, menstrual cramps and irregular periods, premenstrual syndrome (pms).Based on those ingredients, 1,326 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Corydalis yanhusuo extract, Cinnamomum cassia extract, Rehmannia glutinosa extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against China Tung Hsueh Pills by Plum Flower
Ask about any prescription or over-the-counter medication and we check it for interactions with China Tung Hsueh Pills by Plum Flower — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of China Tung Hsueh Pills by Plum Flower
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
China Tung Hsueh Pills contains 11 ingredients, most of them traditional herbal extracts. The active ingredients include Dong Quai (Angelica sinensis), Frankincense (Boswellia carterii), Myrrh (Commiphora myrrha), Elecampane (Inula helenium), Cassia Cinnamon (Cinnamomum cassia), Rehmannia (Rehmannia glutinosa), Sangre de Grado (Daemonorops draco), and Corydalis yanhusuo.
The product also contains a proprietary extract blend—the exact amounts of each herb aren't listed. Three other ingredients—Salvia miltiorrhiza, Styrax tonkinensis, and Dipsacus asper—round out the formula.
Inactive ingredients include hydrated magnesium silicate, activated carbon, and China wax.
Does it work?
Moderate evidence
The evidence base for most of these ingredients is limited. Rehmannia is possibly effective for chronic kidney disease, and Sangre de Grado is possibly effective for HIV/AIDS-related diarrhea and traveler's diarrhea.
For the other conditions the formula may address—anemia, bone health, heart disease, migraines, eczema, acne, back pain, and others—the data we hold shows insufficient reliable evidence to rate whether these ingredients work. That doesn't mean they don't; it means rigorous clinical trials haven't yet established it.
How safe is it?
Well-documented data
Dong Quai is generally well tolerated but can cause burping and flatulence. Frankincense and Myrrh are generally well tolerated short-term.
Elecampane can trigger allergic skin reactions and stomach upset, especially in people sensitive to ragweed or related plants. Cassia Cinnamon is safe in food amounts but at supplement doses may stress the liver over time due to its coumarin content; rare cases of rash and allergy have been reported.
Corydalis yanhusuo has limited human safety data. Pregnancy and breastfeeding are concerns with several ingredients.
Dong Quai and Myrrh are possibly unsafe or likely unsafe in pregnancy; both may stimulate the uterus. Frankincense, Elecampane, Corydalis yanhusuo, Rehmannia, and Sangre de Grado lack enough safety information—avoid them in pregnancy and while breastfeeding unless your doctor advises otherwise.
Cassia Cinnamon is likely safe in food amounts but avoid medicinal doses in pregnancy. We hold no pregnancy or lactation data for Salvia miltiorrhiza, Styrax tonkinensis, or Dipsacus asper.
Meds to double-check
Major interaction found
Before taking this product, check with your pharmacist if you take blood thinners or antiplatelet drugs (including warfarin and aspirin)—Dong Quai and Corydalis yanhusuo raise bleeding risk. Also watch for blood sugar medications, blood pressure medications, CNS depressants (sleep aids and sedatives), estrogen-based birth control or hormone therapy, or any drug your liver metabolizes.
Myrrh may make warfarin less effective, and Cassia Cinnamon at high doses may stress the liver alongside other liver-stressing drugs.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Major medication interactions have been identified, and safety information is well characterized.
This is a traditional herbal formula with limited clinical evidence for most of its uses. It's not suitable during pregnancy or breastfeeding.
If you take blood thinners, blood pressure or blood sugar medications, sedatives, or any drug metabolized by the liver, you need to check your medications against the tool on this page before starting. Talk to your pharmacist about whether this product fits your health picture.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 8 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 27, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about China Tung Hsueh Pills, straight from the product label.
| Brand | Plum Flower |
|---|---|
| Barcode (UPC) | 739934860120 |
| Net contents | 100 Pill(s); 0.88 Ounce(s); 25 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Jul 27, 2021 |
| DSLD ID | 251967 |
| Product type | Botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for China Tung Hsueh Pills by Plum Flower, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Extract Blend | 1250 mg | -- |
| Salvia miltiorrhiza extract | 0 NP | -- |
| Angelica sinensis extract | 0 NP | -- |
| Styrax tonkinensis | 0 NP | -- |
| Boswellia carterii extract | 0 NP | -- |
| Commiphora myrrha extract | 0 NP | -- |
| Inula helenium extract | 0 NP | -- |
| Cinnamomum cassia extract | 0 NP | -- |
| Rehmannia glutinosa extract | 0 NP | -- |
| Dipsacus asper extract | 0 NP | -- |
| Daemonorops draco extract | 0 NP | -- |
| Corydalis yanhusuo extract | 0 NP | -- |
Other ingredients: hydrated Magnesium Silicate, activated Carbon, China Wax
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
GMP Quality
Made in China Plum Flower quality guaranteed
No pharmaceuticals or dyes Unsulfured, preservative-free herbs when available
Microbial and heavy metal tested Produced at a Good Manufacturing Practices (GMP) certified factory
FDA Statement of Identity
Herbal Supplement
Suggested/Recommended/Usage/Directions
Take 5 pills 3 times daily or as directed by your health care practitioner.
Precautions
Not for use during pregnancy.
Keep out of reach of children.
General Statements
US owned and operated since 1969.
Formula
Scientifically authenticated herbs
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
China Tung Hsueh Pills by Plum Flower label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in China Tung Hsueh Pills by Plum Flower
These are the 11 active ingredients this product is made of. Select any to open its full monograph.
Serving size5 Pill(s) Dosage formTablet Or Pill Servings per container20 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Extract Blend
- › Salvia miltiorrhiza extract
- › Angelica sinensis extract
- › Styrax tonkinensis
- › Boswellia carterii extract
- › Commiphora myrrha extract
- › Inula helenium extract
- › Cinnamomum cassia extract
- › Rehmannia glutinosa extract
- › Dipsacus asper extract
- › Daemonorops draco extract
- › Corydalis yanhusuo extract
Other (inactive) ingredients: Hydrated Magnesium Silicate, Activated Carbon, China Wax. These complete the product’s ingredient list but are not active constituents.
China Tung Hsueh Pills by Plum Flower Drug Interactions
HelloPharmacist Interaction Report
China Tung Hsueh Pills by Plum Flower contains several ingredients with documented interactions with medications.
The most serious concern is with blood thinners (anticoagulants): Dong Quai may significantly increase bleeding risk with warfarin, and Corydalis yanhusuo theoretically raises that risk with all anticoagulant and antiplatelet drugs. Both are Major or Moderate severity.
Read the full breakdown — every affected drug type, severity by severity
Other Moderate-severity interactions span several drug categories. Blood sugar medications (antidiabetes drugs) may have additive effects with Cassia Cinnamon, Rehmannia, and Corydalis yanhusuo, raising the risk of low blood sugar (hypoglycemia).
Blood pressure medications (antihypertensive drugs) may be enhanced by Rehmannia and Corydalis yanhusuo. Corydalis yanhusuo also inhibits three liver enzymes—CYP2D6, CYP2C9, and CYP3A4—that break down many common drugs, potentially raising their levels.
CNS depressants (sedatives, sleep aids, pain relievers) may have stronger effects with Elecampane and Corydalis yanhusuo. Dong Quai may theoretically interfere with estrogen-based medications.
Additionally, Myrrh theoretically lowers warfarin's effectiveness, and Cassia Cinnamon may stress the liver when taken at high doses, especially concerning with hepatotoxic drugs. We could not check Salvia miltiorrhiza, Styrax tonkinensis, or Dipsacus asper for interactions; no data are on file for them.
Altogether, these interactions span 1,327 individual medications. Before you start this product, run your exact medications through the checker on this page.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against China Tung Hsueh Pills?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in China Tung Hsueh Pills interact with 1,326 drugs. Click any drug to see the details.
6 of the 11 ingredients in China Tung Hsueh Pills interact with drugs. Each result below shows which ingredient is responsible. Corydalis yanhusuo extract Cinnamomum cassia extract Rehmannia glutinosa extract Inula helenium extract Angelica sinensis extract Commiphora myrrha extract
WarfarinWarfarin
How Warfarin interacts with China Tung Hsueh Pills — through 3 ingredients. Tap an ingredient for the detail:
Angelica Sinensis ExtractAnticoagulant/antiplatelet Drugs, Warfarin (coumadin) Major
Interaction Summary
Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Read the full Angelica Sinensis Extract + Warfarin interactionCorydalis Yanhusuo ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, Corydalis yanhusuo might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Corydalis Yanhusuo Extract + Warfarin interactionCommiphora Myrrha ExtractWarfarin (coumadin) Moderate
Interaction Summary
Theoretically, myrrh might decrease the effectiveness of warfarin.
Read the full Commiphora Myrrha Extract + Warfarin interactionWarfarin SodiumCoumadin, Panwarfin, Sofarin
How Warfarin Sodium interacts with China Tung Hsueh Pills — through 3 ingredients. Tap an ingredient for the detail:
Angelica Sinensis ExtractAnticoagulant/antiplatelet Drugs, Warfarin (coumadin) Major
Interaction Summary
Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Read the full Angelica Sinensis Extract + Warfarin Sodium interactionCorydalis Yanhusuo ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, Corydalis yanhusuo might increase serum levels of drugs metabolized by CYP3A4.
Read the full Corydalis Yanhusuo Extract + Warfarin Sodium interactionCommiphora Myrrha ExtractWarfarin (coumadin) Moderate
Interaction Summary
Theoretically, myrrh might decrease the effectiveness of warfarin.
Read the full Commiphora Myrrha Extract + Warfarin Sodium interaction6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with China Tung Hsueh Pills — through 1 ingredient. Tap an ingredient for the detail:
Cinnamomum Cassia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamomum Cassia Extract + 6-mercaptopurine interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with China Tung Hsueh Pills — through 1 ingredient. Tap an ingredient for the detail:
Corydalis Yanhusuo ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Corydalis yanhusuo might increase serum levels of drugs metabolized by CYP3A4.
Read the full Corydalis Yanhusuo Extract + Ado-trastuzumab Emtansine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with China Tung Hsueh Pills — through 1 ingredient. Tap an ingredient for the detail:
Cinnamomum Cassia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamomum Cassia Extract + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with China Tung Hsueh Pills — through 1 ingredient. Tap an ingredient for the detail:
Cinnamomum Cassia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamomum Cassia Extract + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with China Tung Hsueh Pills — through 2 ingredients. Tap an ingredient for the detail:
Angelica Sinensis ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Read the full Angelica Sinensis Extract + Abciximab interactionCorydalis Yanhusuo ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, Corydalis yanhusuo might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Corydalis Yanhusuo Extract + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with China Tung Hsueh Pills — through 1 ingredient. Tap an ingredient for the detail:
Corydalis Yanhusuo ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Corydalis yanhusuo might increase serum levels of drugs metabolized by CYP3A4.
Read the full Corydalis Yanhusuo Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with China Tung Hsueh Pills — through 2 ingredients. Tap an ingredient for the detail:
Corydalis Yanhusuo ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Corydalis yanhusuo might increase serum levels of drugs metabolized by CYP3A4.
Read the full Corydalis Yanhusuo Extract + Abiraterone interactionCinnamomum Cassia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamomum Cassia Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with China Tung Hsueh Pills — through 2 ingredients. Tap an ingredient for the detail:
Cinnamomum Cassia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamomum Cassia Extract + Abiraterone Acetate interactionCorydalis Yanhusuo ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Corydalis yanhusuo might increase serum levels of drugs metabolized by CYP3A4.
Read the full Corydalis Yanhusuo Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with China Tung Hsueh Pills — through 2 ingredients. Tap an ingredient for the detail:
Angelica Sinensis ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Read the full Angelica Sinensis Extract + Abrocitinib interactionCorydalis Yanhusuo ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, Corydalis yanhusuo might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Corydalis Yanhusuo Extract + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with China Tung Hsueh Pills — through 1 ingredient. Tap an ingredient for the detail:
Corydalis Yanhusuo ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Corydalis yanhusuo might increase serum levels of drugs metabolized by CYP3A4.
Read the full Corydalis Yanhusuo Extract + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with China Tung Hsueh Pills — through 4 ingredients. Tap an ingredient for the detail:
Commiphora Myrrha ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, myrrh might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Commiphora Myrrha Extract + Acarbose interactionCinnamomum Cassia ExtractAntidiabetes Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, cassia cinnamon may have additive effects with antidiabetes drugs.
Read the full Cinnamomum Cassia Extract + Acarbose interactionCorydalis Yanhusuo ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, Corydalis yanhusuo may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Corydalis Yanhusuo Extract + Acarbose interactionRehmannia Glutinosa ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, rehmannia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Rehmannia Glutinosa Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with China Tung Hsueh Pills — through 3 ingredients. Tap an ingredient for the detail:
Corydalis Yanhusuo ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, Corydalis yanhusuo might have additive effects with antihypertensive drugs.
Read the full Corydalis Yanhusuo Extract + Acebutolol interactionCinnamomum Cassia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamomum Cassia Extract + Acebutolol interactionRehmannia Glutinosa ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, rehmannia might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Rehmannia Glutinosa Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with China Tung Hsueh Pills — through 2 ingredients. Tap an ingredient for the detail:
Angelica Sinensis ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Read the full Angelica Sinensis Extract + Acenocoumarol interactionCorydalis Yanhusuo ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, Corydalis yanhusuo might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Corydalis Yanhusuo Extract + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with China Tung Hsueh Pills — through 2 ingredients. Tap an ingredient for the detail:
Inula Helenium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, elecampane may cause additive sedative effects when taken with CNS depressants.
Read the full Inula Helenium Extract + Acepromazine interactionCorydalis Yanhusuo ExtractCns Depressants Moderate
Interaction Summary
Theoretically, Corydalis yanhusuo might increase the sedative effects of CNS depressants.
Read the full Corydalis Yanhusuo Extract + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with China Tung Hsueh Pills — through 1 ingredient. Tap an ingredient for the detail:
Cinnamomum Cassia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamomum Cassia Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with China Tung Hsueh Pills — through 3 ingredients. Tap an ingredient for the detail:
Angelica Sinensis ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Read the full Angelica Sinensis Extract + Acetaminophen, Aspirin interactionCinnamomum Cassia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamomum Cassia Extract + Acetaminophen, Aspirin interactionCorydalis Yanhusuo ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, Corydalis yanhusuo might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Corydalis Yanhusuo Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with China Tung Hsueh Pills — through 3 ingredients. Tap an ingredient for the detail:
Corydalis Yanhusuo ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Corydalis yanhusuo might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Corydalis Yanhusuo Extract + Acetaminophen, Aspirin, Caffeine interactionAngelica Sinensis ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Read the full Angelica Sinensis Extract + Acetaminophen, Aspirin, Caffeine interactionCinnamomum Cassia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamomum Cassia Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with China Tung Hsueh Pills — through 1 ingredient. Tap an ingredient for the detail:
Cinnamomum Cassia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamomum Cassia Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with China Tung Hsueh Pills — through 1 ingredient. Tap an ingredient for the detail:
Cinnamomum Cassia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamomum Cassia Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with China Tung Hsueh Pills — through 2 ingredients. Tap an ingredient for the detail:
Cinnamomum Cassia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamomum Cassia Extract + Acetaminophen, Butalbital, Caffeine interactionCorydalis Yanhusuo ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Corydalis yanhusuo might increase serum levels of drugs metabolized by CYP3A4.
Read the full Corydalis Yanhusuo Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with China Tung Hsueh Pills — through 3 ingredients. Tap an ingredient for the detail:
Corydalis Yanhusuo ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, Corydalis yanhusuo might increase serum levels of drugs metabolized by CYP3A4.
Read the full Corydalis Yanhusuo Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionCinnamomum Cassia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamomum Cassia Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionInula Helenium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, elecampane may cause additive sedative effects when taken with CNS depressants.
Read the full Inula Helenium Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with China Tung Hsueh Pills — through 3 ingredients. Tap an ingredient for the detail:
Inula Helenium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, elecampane may cause additive sedative effects when taken with CNS depressants.
Read the full Inula Helenium Extract + Acetaminophen, Butalbital, Codeine interactionCinnamomum Cassia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamomum Cassia Extract + Acetaminophen, Butalbital, Codeine interactionCorydalis Yanhusuo ExtractCns Depressants, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Corydalis yanhusuo might increase the sedative effects of CNS depressants.
Read the full Corydalis Yanhusuo Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with China Tung Hsueh Pills — through 3 ingredients. Tap an ingredient for the detail:
Corydalis Yanhusuo ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, Corydalis yanhusuo might increase serum levels of drugs metabolized by CYP2D6.
Read the full Corydalis Yanhusuo Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionInula Helenium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, elecampane may cause additive sedative effects when taken with CNS depressants.
Read the full Inula Helenium Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionCinnamomum Cassia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamomum Cassia Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with China Tung Hsueh Pills — through 3 ingredients. Tap an ingredient for the detail:
Cinnamomum Cassia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamomum Cassia Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionCorydalis Yanhusuo ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, Corydalis yanhusuo might increase serum levels of drugs metabolized by CYP2D6.
Read the full Corydalis Yanhusuo Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionInula Helenium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, elecampane may cause additive sedative effects when taken with CNS depressants.
Read the full Inula Helenium Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with China Tung Hsueh Pills — through 3 ingredients. Tap an ingredient for the detail:
Inula Helenium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, elecampane may cause additive sedative effects when taken with CNS depressants.
Read the full Inula Helenium Extract + Acetaminophen, Caffeine, Codeine interactionCorydalis Yanhusuo ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cns Depressants +1 Moderate
Interaction Summary
Theoretically, Corydalis yanhusuo might increase serum levels of drugs metabolized by CYP2D6.
Read the full Corydalis Yanhusuo Extract + Acetaminophen, Caffeine, Codeine interactionCinnamomum Cassia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamomum Cassia Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with China Tung Hsueh Pills — through 3 ingredients. Tap an ingredient for the detail:
Corydalis Yanhusuo ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, Corydalis yanhusuo might increase serum levels of drugs metabolized by CYP3A4.
Read the full Corydalis Yanhusuo Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionInula Helenium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, elecampane may cause additive sedative effects when taken with CNS depressants.
Read the full Inula Helenium Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionCinnamomum Cassia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamomum Cassia Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with China Tung Hsueh Pills — through 3 ingredients. Tap an ingredient for the detail:
Cinnamomum Cassia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamomum Cassia Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionCorydalis Yanhusuo ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, Corydalis yanhusuo might increase serum levels of drugs metabolized by CYP2D6.
Read the full Corydalis Yanhusuo Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionInula Helenium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, elecampane may cause additive sedative effects when taken with CNS depressants.
Read the full Inula Helenium Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with China Tung Hsueh Pills — through 2 ingredients. Tap an ingredient for the detail:
Cinnamomum Cassia ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamomum Cassia Extract + Acetaminophen, Caffeine, Isometheptene interactionCorydalis Yanhusuo ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Corydalis yanhusuo might increase serum levels of drugs metabolized by CYP3A4.
Read the full Corydalis Yanhusuo Extract + Acetaminophen, Caffeine, Isometheptene interactionEach ingredient & the kinds of drugs it affects
For each ingredient in China Tung Hsueh Pills with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Corydalis yanhusuo extract
Anticoagulant/Antiplatelet Drugs
Theoretically, Corydalis yanhusuo might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Corydalis yanhusuo contains berberine. In vitro and in vivo research suggest that berberine can inhibit platelet aggregation. Theoretically, Corydalis yanhusuo might also inhibit platelet aggregation.
Antidiabetes Drugs
Theoretically, Corydalis yanhusuo may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Corydalis yanhusuo contains berberine. Clinical research shows that berberine may lower blood glucose levels. Theoretically, Corydalis yanhusuo might also lower blood glucose levels.
Antihypertensive Drugs
Theoretically, Corydalis yanhusuo might have additive effects with antihypertensive drugs.
Corydalis yanhusuo contains berberine. Animal research suggests that berberine can have hypotensive effects. Also, a clinical study suggests that taking berberine in combination with amlodipine can lower systolic and diastolic blood pressure when compared with amlodipine alone. Theoretically, Corydalis yanhusuo might also reduce blood pressure.
Cns Depressants
Theoretically, Corydalis yanhusuo might increase the sedative effects of CNS depressants.
Corydalis yanhusuo contains berberine. Animal research suggests that berberine may have sedative effects. Theoretically, Corydalis yanhusuo might also have CNS depressants effects.
Cyclosporine (Neoral, Sandimmune)
Theoretically, Corydalis yanhusuo might increase blood levels of cyclosporine.
Corydalis yanhusuo contains berberine. Preliminary clinical research shows that berberine can reduce metabolism of cyclosporine and increase serum levels, likely through inhibition of cytochrome P450 3A4 (CYP3A4), which metabolizes cyclosporine. Theoretically, Corydalis yanhusuo might also reduce the metabolism of cyclosporine.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, Corydalis yanhusuo might increase serum levels of drugs metabolized by CYP2C9.
Corydalis yanhusuo contains berberine. Preliminary clinical research shows that berberine can inhibit CYP2C9. Theoretically, Corydalis yanhusuo might also inhibit CYP2C9.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, Corydalis yanhusuo might increase serum levels of drugs metabolized by CYP2D6.
Corydalis yanhusuo contains berberine. In vitro research and preliminary clinical evidence show that berberine can inhibit CYP2D6. Theoretically, Corydalis yanhusuo might also inhibit CYP2D6.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, Corydalis yanhusuo might increase serum levels of drugs metabolized by CYP3A4.
Corydalis yanhusuo contains berberine. In vitro research and preliminary clinical research show that berberine moderately inhibits CYP3A4. Theoretically, Corydalis yanhusuo might also inhibit CYP3A4.
Dextromethorphan (Robitussin Dm, Others)
Theoretically, Corydalis yanhusuo may increase serum levels of dextromethorphan.
Corydalis yanhusuo contains berberine. Preliminary clinical research shows that berberine can inhibit cytochrome P450 2D6 (CYP2D6) activity and reduce the metabolism of dextromethorphan. Theoretically, Corydalis yanhusuo may also inhibit the metabolism of dextromethorphan.
Losartan (Cozaar)
Theoretically, Corydalis yanhusuo might reduce the therapeutic effects of losartan by decreasing its conversion to its active form.
Corydalis yanhusuo contains berberine. Preliminary clinical research suggests that berberine can inhibit cytochrome P450 2C9 (CYP2C9) activity and reduce metabolism of losartan. Theoretically, Corydalis yanhusuo might also inhibit the metabolism of losartan.
Metformin (Glucophage)
Theoretically, Corydalis yanhusuo might increase the therapeutic and adverse effects of metformin.
Corydalis yanhusuo contains berberine. In vitro and animal studies show that berberine can increase the systemic exposure and half-life of metformin, potentially increasing metformin's effects and side effects. This interaction seems to be most apparent when berberine is administered 2 hours prior to metformin. Taking berberine and metformin at the same time does not appear to increase systemic exposure to metformin. It is unclear if Corydalis yanhusuo might have this same effect.
Midazolam (Versed)
Theoretically, Corydalis yanhusuo might reduce metabolism of midazolam, which might increase the risk of severe adverse effects.
Corydalis yanhusuo contains berberine. Preliminary clinical research shows that berberine can inhibit cytochrome P450 3A4 (CYP3A4) activity and reduce metabolism of midazolam. Theoretically, Corydalis yanhusuo might also inhibit the metabolism of midazolam.
Pentobarbital (Nembutal)
Theoretically, Corydalis yanhusuo might increase the sedative effect of pentobarbital.
Corydalis yanhusuo contains berberine. Animal research shows that berberine can prolong pentobarbital-induced sleeping time. Theoretically, Corydalis yanhusuo might increase the sedative effects of pentobarbital.
Tacrolimus (Prograf)
Theoretically, Corydalis yanhusuo might increase blood levels of tacrolimus.
Corydalis yanhusuo contains berberine. In a 16-year-old patient with idiopathic nephrotic syndrome who was being treated with tacrolimus 6.5 mg twice daily, intake of berberine 200 mg three times daily increased the blood concentration of tacrolimus from 8 to 22 ng/mL. Following a reduction of the tacrolimus dose to 3 mg daily, blood levels of tacrolimus decreased to 12 ng/mL. It is unclear if Corydalis yanhusuo might have this same effect.
Cinnamomum cassia extract
Antidiabetes Drugs
Theoretically, cassia cinnamon may have additive effects with antidiabetes drugs.
Cassia cinnamon may lower blood glucose levels, and have additive effects in patients treated with antidiabetic agents. Dose adjustments to diabetes medications might be necessary.
Hepatotoxic Drugs
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
There is some concern that ingesting large amounts of cassia cinnamon for an extended duration might cause hepatotoxicity in some people. Cassia cinnamon contains coumarin, which can cause hepatotoxicity in animal models. In humans, very high doses of coumarin from 50-7000 mg/day can result in hepatotoxicity that resolves when coumarin use is discontinued. Lower amounts might also cause liver problems in sensitive people, such as those with liver disease or those taking potentially hepatotoxic agents.
Rehmannia glutinosa extract
Antidiabetes Drugs
Theoretically, rehmannia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research shows that rehmannia may have hypoglycemic effects.
Antihypertensive Drugs
Theoretically, rehmannia might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research shows that rehmannia may have hypotensive effects. Laboratory research shows that formulations of dried and processed rehmannia root inhibit angiotensin-converting enzyme (ACE).
Inula helenium extract
Cns Depressants
Theoretically, elecampane may cause additive sedative effects when taken with CNS depressants.
Elecampane might have sedative effects.
Angelica sinensis extract
Warfarin (Coumadin)
Dong quai may increase the risk of bleeding when used with warfarin.
Case reports suggest that concomitant use of dong quai with warfarin can increase the anticoagulant effects of warfarin and increase the risk of bleeding. In one case, after 4 weeks of taking dong quai 565 mg once or twice daily, the international normalized ratio (INR) increased to 4.9. The INR normalized 4 weeks after discontinuation of dong quai.
Anticoagulant/Antiplatelet Drugs
Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Animal studies suggest that dong quai has antithrombin activity and inhibits platelet aggregation due to its coumarin components. Additionally, some case reports in humans suggest that dong quai can increase the anticoagulant effects of warfarin. However, clinical research in healthy adults shows that taking 1 gram of dong quai root daily for 3 weeks does not significantly inhibit platelet aggregation or cause bleeding. Until more is known, use dong quai with caution in patients taking antiplatelet/anticoagulant drugs.
Estrogens
Theoretically, dong quai may reduce the effects of estrogens.
Dong quai has estrogenic effects. Theoretically, concomitant use of large amounts of dong quai might interfere with hormone replacement therapy due to competition for estrogen receptors.
Commiphora myrrha extract
Antidiabetes Drugs
Theoretically, myrrh might increase the risk of hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research suggests that myrrh has hypoglycemic effects.
Warfarin (Coumadin)
Theoretically, myrrh might decrease the effectiveness of warfarin.
In one case, a patient who was previously stable on warfarin had a significant decline in international normalized ratio (INR) following consumption of an aqueous extract of myrrh.
Brand information
Manufacturer and brand details for China Tung Hsueh Pills, from the product label.
Plum Flower
- Name
- Mayway Herbs
- City
- Oakland
- State
- CA
- Web Address
- www.plumflowerherbs.com
China Tung Hsueh Pills by Plum Flower: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind China Tung Hsueh Pills’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Dong Quai
Interacts with 163 drugsDong Quai is a traditional Chinese herb often called "female ginseng" and is mostly used for menstrual and menopausal complaints. High-quality scientific evidence that it works for these use...
Read the full Dong Quai monograph → Herb & supplement monographFrankincense
Frankincense is the aromatic resin of the Boswellia tree and is best known for its boswellic acids, which may help with inflammation and joint pain. Early research is promising for condition...
Read the full Frankincense monograph → Herb & supplement monographMyrrh
Interacts with 88 drugsMyrrh is a fragrant gum resin from Commiphora trees that has long been used in mouthwashes, throat remedies, and skin care. Modern evidence for most of its uses is limited and comes mostly f...
Read the full Myrrh monograph → Herb & supplement monographElecampane
Interacts with 248 drugsElecampane is a traditional herb used mainly for coughs and other respiratory complaints, and as a bitter for digestion. Modern human evidence is very limited, so it should be seen as a folk...
Read the full Elecampane monograph → Herb & supplement monographCassia Cinnamon
Interacts with 442 drugsCassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evidence for its health benefits is mixed a...
Read the full Cassia Cinnamon monograph → Herb & supplement monographRehmannia
Interacts with 258 drugsRehmannia is a root used for centuries in Traditional Chinese Medicine, often to 'tonify' the kidneys and support energy or blood health. Human evidence for most modern uses is limited, so i...
Read the full Rehmannia monograph → Herb & supplement monographSangre De Grado
Sangre de Grado is a red tree sap from the Amazon rainforest used traditionally for diarrhea, wounds, and skin problems. Some of its compounds have been studied scientifically, and one purif...
Read the full Sangre De Grado monograph → Herb & supplement monographCorydalis Yanhusuo
Interacts with 1,160 drugsCorydalis yanhusuo is a traditional Chinese herb used mainly for pain. Some early laboratory and animal research suggests its compounds may affect pain and the nervous system, but high-quali...
Read the full Corydalis Yanhusuo monograph →Sources & How We Checked
China Tung Hsueh Pills's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 87 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Dong Quai 19 references
- Hirata JD, Swiersz LM, Zell B, et al. Does dong quai have estrogenic effects in postmenopausal women? A double-blind, placebo-controlled trial. Fertil Steril 1997;68:981-6. PubMed
- Page RL II, Lawrence JD. Potentiation of warfarin by dong quai. Pharmacotherapy 1999;19:870-6. PubMed
- Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
- Eagon PK, Elm MS, Hunter DS, et al. Medicinal herbs: modulation of estrogen action. Era of Hope Mtg, Dept Defense; Breast Cancer Res Prog, Atlanta, GA 2000;Jun 8-11.
- Dr. Duke's Phytochemical and Ethnobotanical Databases. Available at: http://www.ars-grin.gov/duke/.
- Amato P, Christophe S, Mellon PL. Estrogenic activity of herbs commonly used as remedies for menopausal symptoms. Menopause 2002;9:145-50. PubMed
- Shi M, Chang L, He G. [Stimulating action of Carthamus tinctorius L., Angelica sinensis (Oliv.) Diels and Leonurus sibiricus L. on the uterus]. Zhongguo Zhong Yao Za Zhi 1995;20:173-5, 192.
- Hoult JR, Paya M. Pharmacological and biochemical actions of simple coumarins: natural products with therapeutic potential. Gen Pharmacol 1996;27:713-22.. PubMed
- Cheong JL, Bucknall R. Retinal vein thrombosis associated with a herbal phytoestrogen preparation in a susceptible patient. Postgrad Med J 2005;81:266-7.. PubMed
- Chang CJ, Chiu JH, Tseng LM, et al. Modulation of HER2 expression by ferulic acid on human breast cancer MCF7 cells. Eur J Clin Invest 2006;36:588-96. PubMed
- Chuang CH, Doyle P, Wang JD, et al. Herbal medicines used during the first trimester and major congenital malformations: an analysis of data from a pregnancy cohort study. Drug Saf 2006;29:537-48. PubMed
- Lau CBS, Ho TCY, Chan TWL, Kim SCF. Use of dong quai (Angelica sinensis) to treat peri- and postmenopausal symptoms in women with breast cancer: is it appropriate? Menopause 2005;12:734-40.
- Ellis GR, Stephens MR. Untitled (photograph and a brief case report). BMJ 1999;319:650.
- Nambiar, S., Schwartz, R. H., and Constantino, A. Hypertension in mother and baby linked to ingestion of Chinese herbal medicine. West J Med 1999;171(3):152.
- Lee, S. K., Cho, H. K., Cho, S. H., Kim, S. S., Nahm, D. H., and Park, H. S. Occupational asthma and rhinitis caused by multiple herbal agents in a pharmacist. Ann.Allergy Asthma Immunol. 2001;86(4):469-474. PubMed
- Xu, J. and Li, G. [Observation on short-term effects of Angelica injection on chronic obstructive pulmonary disease patients with pulmonary hypertension]. Zhongguo Zhong Xi Yi Jie He Za Zhi 2000;20(3):187-189.
- Scott, G. N. and Elmer, G. W. Update on natural product--drug interactions. Am J Health Syst.Pharm 2-15-2002;59(4):339-347. PubMed
- Circosta, C., Pasquale, R. D., Palumbo, D. R., Samperi, S., and Occhiuto, F. Estrogenic activity of standardized extract of Angelica sinensis. Phytother.Res. 2006;20(8):665-669.
- Fung FY, Wong WH, Ang SK, et al. A randomized, double-blind, placebo- controlled study on the anti-haemostatic effects of Curcuma longa, Angelica sinensis and Panax ginseng. Phytomedicine. 2017;32:88-96. PubMed
Frankincense 2 references
- Acebo, E., Raton, J. A., Sautua, S., Eizaguirre, X., Trebol, I., and Perez, J. L. Allergic contact dermatitis from Boswellia serrata extract in a naturopathic cream. Contact Dermatitis 2004;51(2):91-92.
- Buonomo M, Hylwa S. Allergic contact dermatitis from Boswellia carterii (frankincense) oil. Contact Dermatitis 2021;85(4):465-467.
Myrrh 8 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Al Faraj S. Antagonism of the anticoagulant effect of warfarin caused by the use of Commiphora molmol as a herbal medication: a case report. Ann Trop Med Parasitol 2005;99:219-20.
- Al-Jaroudi D, Kaddour O, Al-Amin N. Risks of myrrh use in pregnancy. JBRA Assist Reprod 2016;20(4):257-8.
- Xu YY, Li L, Xuan L, Guan K. Patch test diagnosis of non-immediate cutaneous reaction to myrrh following oral intake of a traditional Chinese medicine decoction. Contact Dermatitis. 2019;80(2):135-136. PubMed
- Al-Romaiyan A, Huang GC, Jones P, Persaud S. Commiphora myrrha stimulates insulin secretion from mouse and human islets of Langerhans. J Ethnopharmacol. 2021 Jan 10;264:113075. PubMed
Elecampane 5 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Lamminpaa A, Estlander T, Jolanki R, Kanerva L. Occupational allergic contact dermatitis caused by decorative plants. Contact Dermatitis 1996;34:330-5. PubMed
- Pazzaglia, M., Venturo, N., Borda, G., and Tosti, A. Contact dermatitis due to a massage liniment containing Inula helenium extract. Contact Dermatitis 1995;33(4):267.
- Aalto-Korte, K., Alanko, K., Kuuliala, O., and Jolanki, R. Late reactions in patch tests: a 4-year review from a clinic of occupational dermatology. Contact Dermatitis 2007;56(2):81-86. PubMed
Cassia Cinnamon 20 references
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Khan A, Safdar M, Ali Khan M, et al. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 2003;26:3215-8. PubMed
- De Benito V, Alzaga R. Occupational allergic contact dermatitis from cassia (Chinese cinnamon) as a flavouring agent in coffee. Contact Dermatitis 1999;40:165. PubMed
- Drake TE, Maibach HI. Allergic contact dermatitis and stomatitis caused by a cinnamic aldehyde-flavored toothpaste. Arch Dermatol 1976;112:202-3.
- Press release. Cinnamon capsules to reduce blood sugar are medicinal products! Efficacy has not been scientifically proven - some products contain high levels of coumarin. Federal Institute of Risk Assessment (BfM), Germany, November 11, 2006. Available a
- Felter SP, Vassallo JD, Carlton BD, Daston GP. A safety assessment of coumarin taking into account species-specificity of toxicokinetics. Food Chem Toxicol 2006;44:462-75. PubMed
- Crawford P. Effectiveness of cinnamon for lowering hemoglobin A1C in patients with type 2 diabetes: a randomized, controlled trial. J Am Board Fam Med 2009;22:507-12. PubMed
- Akilen, R., Tsiami, A., Devendra, D., and Robinson, N. Glycated haemoglobin and blood pressure-lowering effect of cinnamon in multi-ethnic Type 2 diabetic patients in the UK: a randomized, placebo-controlled, double-blind clinical trial. Diabet.Med. 2010; PubMed
- Lu T, Sheng H Wu J Cheng Y Zhu J Chen Y. Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes. Nutr Res. 2012;32(6):408-412. PubMed
- Choi, J., Lee, K. T., Ka, H., Jung, W. T., Jung, H. J., and Park, H. J. Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties. Arch Pharm Res 2001;24(5):418-423.
- Altschuler JA, Casella SJ, MacKenzie TA, Curtis KM. The effect of cinnamon on A1C among adolescents with type 1 diabetes. Diabetes Care 2007;30(4):813-6. PubMed
- Stoecker BR, Zhan Z, Luo R, et al. Cinnamon extract lowers blood glucose in hyperglycemic subjects. FASEB J. 2010;22:722.1 (Abstract only). DOI
- Admani S, Hill H, Jacob SE. Cinnamon Sugar Scrub Dermatitis: "Natural" Is Not Always Best. Pediatr Dermatol. 2017;34(1):e42-e43. PubMed
- Isaac-Renton M, Li MK, Parsons LM. Cinnamon spice and everything not nice: many features of intraoral allergy to cinnamic aldehyde. Dermatitis. 2015;26(3):116-21. PubMed
- Vandersall A, Katta R. Eyelid dermatitis as a manifestation of systemic contact dermatitis to cinnamon. Dermatitis. 2015 Jul-Aug;26(4):189. PubMed
- Wickenberg J, Lindstedt S, Nilsson J, Hlebowicz J. Cassia cinnamon does not change the insulin sensitivity or the liver enzymes in subjects with impaired glucose tolerance. Nutr J 2014 Sep 24;13:96. PubMed
- Brancheau D, Patel B, Zughaib M. Do cinnamon supplements cause acute hepatitis? Am J Case Rep 2015;16:250-4. PubMed
- Shekarchizadeh-Esfahani P, Heydarpour F, Izadi F, Jalili C. The effect of cinnamon supplementation on liver enzymes in adults: A systematic review and meta-analysis of randomized controlled trials. Complement Ther Med 2021;58:102699. PubMed
- Bernaola J, Valverde-Monge M, Otal-Buesa M, Cullen D, Heras-Mendaza F. Cinnamon allergic contact cheilitis. Contact Dermatitis 2023;88(5):418-419. PubMed
- Patel K, Howard M, Tate B. Cheilitis caused by allergic contact dermatitis to cinnamon in chai tea: A case report. Contact Dermatitis 2023;88(3):239-240. PubMed
Rehmannia 3 references
- Zhang R, Zhou J, Jia Z, et al. Hypoglycemic effect of Rehmannia glutinosa oligosaccharide in hyperglycemic and alloxan-induced diabetic rats and its mechanism. J Ethnopharmacol 2004;90:39-43. PubMed
- Zhang RX, Li MX, Jia ZP. Rehmannia glutinosa: review of botany, chemistry and pharmacology. J Ethnopharmacol 2008;117(2):199-214. PubMed
- Chao CH, Hsu JL, Chen MF, et al. Anti-hypertensive effects of Radix Rehmanniae and its active ingredients. Nat Prod Res. 2020;34(11):1547-1552.
Sangre De Grado 9 references
- Holodniy M, Koch J, Mistal M, et al. A double blind, randomized, placebo-controlled phase II study to assess the safety and efficacy of orally administered SP-303 for the symptomatic treatment of diarrhea in patients with AIDS. Am J Gastroenterol 1999;9 PubMed
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