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Dietary supplement

Durian Ingredients & Drug Interactions

by Herbal Terra

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Durian is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for general nutrition and energy, traditional tonic or aphrodisiac, digestive support.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Durian Fruit Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Durian by Herbal Terra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Durian Fruit Extract in dry form. Durian is a tropical fruit sometimes called the "king of fruits." The extract is delivered in a liquid form and includes alcohol, water, and glycerin as inactive ingredients to keep it stable and palatable.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Durian product and its label doesn't state a use — see Durian's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't hold effectiveness ratings for Durian Fruit Extract in our data, so the evidence for what this supplement actually does isn't established here. If you're considering it for a specific reason, ask us what the intended use is and we can point you toward what's known.

The evidence, ingredient by ingredient Durian

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Durian is generally well tolerated as a food in moderation, but it's high in sugar and calories—so if you're watching either, keep portions small. The data on supplement forms like this one is limited, so use it as an occasional food rather than a daily dose, and check with your doctor or pharmacist first.

Rare adverse effects reported in case studies include abdominal discomfort, flatulence, diarrhea, vomiting, and allergic reactions (hives, nasal congestion, runny nose, and hoarseness). These are uncommon, but if you've had any reaction to durian fruit before, be cautious with the extract.

Side effects, ingredient by ingredient Durian

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Durian.
  • The most serious interaction on file is rated Moderate.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications if you drink alcohol regularly or take any drug that interacts with it—the interaction here is Moderate in severity. Since this liquid product contains alcohol as an inactive ingredient, the risk is especially relevant.

Use the tool on this page to scan your exact medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you enjoy durian as a food and want to try this extract, it's likely fine—but don't mix it with alcohol on the same day, and ask your pharmacist first if you drink regularly or take medications that interact with alcohol. The data on supplement use is thinner than for eating the fruit itself, so start conservatively and watch how you feel.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Durian, straight from the product label.

Brand Herbal Terra
Barcode (UPC) 7386005055942
Net contents 2 Fluid Ounce(s); 60 mL
Market status On market
Date entered into DSLD Jan 23, 2025
DSLD ID 325000
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Durian by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
60
UPC/BARCODE
7386005055942
IngredientAmount% DV
Durian Fruit Extract, Dry983 mg--

Other ingredients: Alcohol, Water, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz. of juice or water up to 4 times a day.

Precautions

We recommend to seek expert medical advice before taking. May have contraindications and cause adverse reaction.

Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications.

Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications. Keep out of the reach of children!

Do not use if you are allergic to any ingredients.

Storage

Store in a cool, dry, dark place.

FDA Disclaimer Statement

This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.

Formulation

cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.

Sugar free

Expertly extracted 100% natural Premium product

Organic alcohol

No artificial ingredients, color additives, fillers or binders.

Natural Gluten free

Formula

Durio zibethinus

Organic alcohol

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Made in USA

General Statements

Organic raw material.

See for yourself

Durian by Herbal Terra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Durian by Herbal Terra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.

Durian Fruit Extract, Dry

Interacts with
1 drug
983 mg per serving Form: Durio zibethinus Fruit Extract, Dry

Durian is a popular tropical fruit valued mainly as a nutritious food rich in carbohydrates, fiber, vitamins, and antioxidants. While it has many trad...

Durian Fruit Extract, Dry monograph & interactions

Other (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Durian by Herbal Terra Drug Interactions

Want to check YOUR meds against Durian?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Durian with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Durian Fruit Extract, Dry1 drug type · 1 drug

Alcohol (Ethanol)

There is a traditional belief that ingestion of alcohol with durian can be fatal. A case report from 1941 describes an adult in India who developed acute hemorrhagic pancreatitis and died after drinking alcohol with durian, but there have been no other published reports since. A study in mice given homogenized durian fruit flesh in 10% ethanol did not demonstrate any toxicity. However, evidence from in vitro research shows that durian extract can inhibit alcohol dehydrogenase. This activity is similar to the effects of disulfiram. In theory, concomitant use might cause effects similar to disulfiram-ethanol reactions. Until more is known, avoid concomitant use of durian and alcohol.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Durian, from the product label.

Herbal Terra

See all Herbal Terra products
Name
Herbal Terra LLC
Phone Number
+18083857868
Web Address
herbalterra.com
Pharmacist Counseling Corner

Durian by Herbal Terra: Common Questions

Does Durian by Herbal Terra interact with any medications?
Yes. Based on its ingredients, Durian has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Durian contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I drink alcohol?
Not on the same day, ideally. There's a historical case of severe illness after combining durian with alcohol, though it's rare. Also, this liquid product itself contains alcohol, so drinking it plus alcoholic beverages stacks the alcohol exposure. If you drink regularly, talk with your pharmacist before starting.
What is durian, and what's it supposed to do?
Durian is a tropical fruit known for its pungent smell. We don't have effectiveness data on file for this extract, so I can't tell you what benefit it's meant to provide—let me know what you're hoping it'll help with, and we can look into it together.
Is it safe to use every day?
The data on daily supplement use is lacking. Durian is safe as an occasional food but high in sugar and calories. If you're thinking of using this regularly, check with your doctor or pharmacist first to make sure it fits your health needs.
Can I take this while pregnant or breastfeeding?
We don't have safety data for durian supplements during pregnancy or lactation on file. This is something to talk through with your OB or midwife—they'll know your full history and can give you personalized advice.
What side effects should I watch for?
Most people tolerate durian well, but case reports mention abdominal discomfort, bloating, diarrhea, and vomiting. Allergic reactions (hives, nasal congestion, hoarseness) are rare but possible. If you've reacted to durian fruit before, skip the extract.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Durian is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Durian label
Sources

Sources & How We Checked

Durian's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Durian 5 references
  1. Singh, P. Journal of the Malaya Branch British Medical Association 1941;5(1):62-63.
  2. Olivieri, J., Quiliquini-Chambard, A. M., and Hauser, C. Allergy to durian. Allergy 2002;57(3):263.
  3. Ogle, C. W. and Teh, Y. F. Durian and alcohol. A preliminary report. Singapore Med J 1969;10(4):288-290.
  4. Maninang JS, Lizada, MCC, Gemma, H. Inhibition of aldehyde dehydrogenase enzyme by Durian (Durio zibethinus Murray) fruit extract. Food Chem 2009;117(2):352-355. DOI
  5. Husin NA, Rahman S, Karunakaran R, Bhore SJ. A review on the nutritional, medicinal, molecular and genome attributes of Durian (Durio zibethinus L.) the king of fruits in Malaysia. Bioinformation 2018;14(6):265-70. PubMed

See these in context on the Durian monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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