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Dietary supplement

Elderberry Zinc Immune Support Syrup Ingredients & Drug Interactions

by MegaFood

Elderberry Zinc Immune Support Syrup label
See full label image
Liquid Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Elderberry Zinc Immune Support Syrup against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Elderberry Zinc Immune Support Syrup is a dietary supplement by MegaFood with 3 active ingredients. Its ingredients are commonly taken for zinc deficiency, immune support, cold symptoms.Based on those ingredients, 952 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Aronia Berry Fruit Juice Concentrate, Elderberry Fruit Extract, Zinc. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Elderberry Zinc Immune Support Syrup by MegaFood

Ask about any prescription or over-the-counter medication and we check it for interactions with Elderberry Zinc Immune Support Syrup by MegaFood — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Elderberry Zinc Immune Support Syrup by MegaFood

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This syrup contains 3 active ingredients: zinc, elderberry fruit extract, and aronia berry juice concentrate. Zinc supports immune function and is used for zinc deficiency and other conditions.

Elderberry and aronia berry are fruit extracts — both traditional immune-support ingredients, though the evidence for their specific benefits isn't well established in our data. The product also contains inactive ingredients (glycerin, water, natural flavors, and citrus extract) that give it form and taste.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: immune system support.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

Zinc is effective for zinc deficiency and likely effective for Wilson disease; it's possibly effective for acne, age-related macular degeneration (AMD), diabetes, and acrodermatitis enteropathica. Elderberry fruit extract has insufficient evidence to rate for allergic rhinitis, cardiovascular disease, chronic fatigue syndrome, COPD, cognitive function, and respiratory tract infections — meaning we don't have solid data showing whether it works for these uses.

Aronia berry shows possibly ineffective for cardiovascular disease in the data we hold; for other uses like age-related macular degeneration and cognitive decline, the evidence is insufficient to rate.

The evidence, ingredient by ingredient Zinc Elderberry Chokeberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Zinc is generally well tolerated in doses below 40 mg daily for adults. At doses below that limit, the most common side effects are abdominal cramps, diarrhea, metallic taste, nausea, and vomiting — all dose-related and usually mild.

High-dose zinc over the long term raises concern for copper deficiency, which can lead to anemia and low white blood cell counts. Elderberry extract from ripe, cooked fruit is generally well tolerated; raw or unripe berries and other plant parts contain toxins that cause nausea, vomiting, severe diarrhea, weakness, and dizziness (cooking eliminates this risk).

One case report linked long-term elderberry use to autoimmune hepatitis, though this is rare. Aronia berry is generally well tolerated as a food, though concentrated supplements are less studied; in small studies, around 14–53% of people drinking the juice reported constipation, diarrhea, nausea, stomach cramps, or vomiting.

Side effects, ingredient by ingredient Zinc Elderberry Chokeberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Elderberry, Zinc, Chokeberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 953 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your own doctor or pharmacist if you take quinolone or tetracycline antibiotics, cephalexin (Keflex), penicillamine (Cuprimine, Depen), blood thinners or antiplatelet drugs, diabetes medications, HIV drugs (ritonavir, integrase inhibitors, or Biktarvy), cisplatin or trabectedin (chemotherapy agents), or any drug metabolized by CYP3A4 enzymes. Zinc requires spacing — at least 2 hours before or 4–6 hours after these antibiotics — to prevent it from blocking their absorption and making them less effective.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This syrup is a multiingredient immune support product; zinc has the strongest evidence base. It carries Moderate interactions with antibiotics, blood thinners, diabetes drugs, HIV medications, and some chemotherapy agents — so if you take any prescription medication, check it with your own doctor or pharmacist before starting.

Zinc alone is generally well tolerated in recommended doses, and the fruit extracts are usually gentle, though some people experience mild digestive upset. Talk it over with your healthcare provider to make sure it fits your health picture.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Elderberry Zinc Immune Support Syrup, straight from the product label.

Brand MegaFood
Net contents 4 Fluid Ounce(s); 120 Milliliter(s)
Market status On market
Date entered into DSLD Jun 22, 2023
DSLD ID 287371
Product type Botanical With Nutrients
Supplement form Liquid
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Elderberry Zinc Immune Support Syrup by MegaFood, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
7.5 mL
Maximum serving Sizes:
7.5 mL
Servings per container
16
IngredientAmount% DV
Calories20 Calorie(s)--
Total Carbohydrate5 Gram(s)2%
Zinc11 mg100%
Elderberry Fruit Extract2272 mg--
Aronia Berry Fruit Juice Concentrate500 mg--

Other ingredients: Glycerin, Water, Natural Flavors, Citrus extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Supports a healthy immune system

Certified organic by QAI

Vegetarian

Tested Gluten free Dairy free soy free Tested 125+ Pesticides & Herbicides Glyphosate Residue Free detoxproject.org

Formula

Provides 100% daily value of zinc

MegaFood Elderberry Zinc Immune Support Syrup uniquely pairs elderberry and zinc to support a healthy immune system.

One serving includes 100% of your daily value for zinc, a nutrient that is essential for healthy immune function, while elderberry and Aronia berry are super fruits that provide additional phytonutrients.

This product can support the immune health of any person in the family, age 4 and up.

Seals/Symbols

USDA Organic Non GMO Project Verified nongmoproject.org

Glyphosate Residue free detoxproject.org Certified B Corporations Tested 125+ Pesticides & Herbicides

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Shake well before use. Adults and children 4 years and older, take one 7.5 mL cup serving per day (serving cup included).

Precautions

If pregnant, nursing, or you have a health condition, consult your healthcare practitioner before taking this product.

Keep out of reach of children.

Once open, consume within two months.

Storage

Store tightly sealed in a cool place and refrigerate after opening.

General Statements

We are a vitamin and supplement company working to help grow a healthier world. Since 1973, we've been dedicated to producing high-quality supplements. We pair key vitamins and minerals with real food ingredients to support your optimal wellness.

To learn about our seals, please visit megafood.com/standards.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Elderberry Zinc Immune Support Syrup by MegaFood label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Elderberry Zinc Immune Support Syrup label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Elderberry Zinc Immune Support Syrup by MegaFood

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size7.5 mL Dosage formLiquid Servings per container16 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Zinc

Interacts with
67 drugs
11 mg per serving Form: Zinc Citrate

Zinc is an essential mineral that your body needs for immune function, wound healing, taste, and smell. Most people get enough from food, but suppleme...

Zinc monograph & interactions

Elderberry Fruit Extract

Interacts with
121 drugs
2272 mg per serving Form: Sambucus nigra Fruit Extract

Elderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu sym...

Elderberry Fruit Extract monograph & interactions

Aronia Berry Fruit Juice Concentrate

Interacts with
811 drugs
500 mg per serving Form: Aronia melanocarpa Berry Fruit Juice Concentrate

Chokeberry (aronia) is a dark berry rich in antioxidants called polyphenols, and it's widely eaten as juice, jam, and supplements. Early research hint...

Aronia Berry Fruit Juice Concentrate monograph & interactions

Other (inactive) ingredients: Glycerin, Water, Natural Flavors, Citrus extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Elderberry Zinc Immune Support Syrup by MegaFood Drug Interactions

Want to check YOUR meds against Elderberry Zinc Immune Support Syrup?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
952Drugs
950 Moderate 2 Minor

Ingredients driving the most interactions

Aronia Berry Fruit Juice Concentrate 811
Elderberry Fruit Extract 121
Zinc 67

Individual Drug Interactions

The ingredients in Elderberry Zinc Immune Support Syrup interact with 952 drugs. Click any drug to see the details.

3 of the 3 ingredients in Elderberry Zinc Immune Support Syrup interact with drugs. Each result below shows which ingredient is responsible. Aronia Berry Fruit Juice Concentrate Elderberry Fruit Extract Zinc

Each ingredient & the kinds of drugs it affects

For each ingredient in Elderberry Zinc Immune Support Syrup with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Aronia Berry Fruit Juice Concentrate4 drug types · 811 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, chokeberry might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Clinical and in vitro research suggests that chokeberry extract can temporarily inhibit platelet aggregation and decrease clot formation.

Likelihood Possible Evidence B
Antidiabetes Drugs

Theoretically, chokeberry might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Some clinical research shows that chokeberry decreases levels of blood glucose in some patients with diabetes. However, other clinical research suggests that chokeberry has no significant effect on blood glucose levels.

Likelihood Possible Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
In vitro research shows that chokeberry inhibits CYP3A4. In humans, there is one case report of a drug interaction with trabectedin, a CYP3A4 substrate, which is hypothesized to have been caused by chokeberry inhibition of CYP3A4.

Likelihood Possible Evidence D
Trabectedin (Yondelis)

Theoretically, chokeberry might increase the effects and adverse effects of trabectedin.
In one case report, a patient drinking chokeberry juice developed rhabdomyolysis induced by trabectedin, a cytochrome P450 3A4 (CYP3A4) substrate. It is possible that inhibition of CYP3A4 by chokeberry juice might have inhibited the metabolism of trabectedin and increased trabectedin levels in this patient.

Likelihood Possible Evidence D
Aronia Berry Fruit Juice Concentrate full monograph & interactions

Elderberry Fruit Extract2 drug types · 121 drugs

Immunosuppressants

Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Elderberry has immunostimulant activity, increasing the production of cytokines, including interleukin and tumor necrosis factor.

Likelihood Possible Evidence B
Pazopanib (Votrient)

Theoretically, elderberry might interact with pazopanib, potentially increasing the risk of adverse effects.
In one case, a 65-year-old patient taking pazopanib for 4 weeks for soft-tissue sarcoma developed severe nausea, loose stools, and elevated alanine transaminase and aspartate transaminase levels and was diagnosed with grade 3 liver injury. The patient reported taking elderberry supplements for 2 years, dose unspecified, and was also taking a multivitamin and a calcium supplement. The patient's symptoms and liver enzyme levels improved upon discontinuation of pazopanib and all supplements. Pazopanib treatment was re-initiated, at a lower dose, with no further evidence of liver injury. It was unclear in this case report if the elderberry supplements were derived from the berry, the flower, or the combination.

Likelihood Possible Evidence D
Elderberry Fruit Extract full monograph & interactions

Zinc10 drug types · 67 drugs

Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Theoretically, zinc might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide should be taken at least 2 hours before or 6 hours after zinc containing products.

Likelihood Probable Evidence D
Cephalexin (Keflex)

Zinc might decrease cephalexin levels by chelating with cephalexin in the gut and preventing its absorption.
A pharmacokinetic study shows that zinc sulfate 250 mg taken concomitantly with cephalexin 500 mg decreases peak levels of cephalexin by 31% and reduces the exposure to cephalexin by 27%. Also, taking zinc sulfate 3 hours before cephalexin decreases peak levels of cephalexin by 11% and reduces the exposure to cephalexin by 18%. By decreasing cephalexin levels, zinc might increase the risk of treatment failure. This effect does not occur when zinc is taken 3 hours after the cephalexin dose. To avoid an interaction, advise patients take zinc sulfate 3 hours after taking cephalexin.

Likelihood Probable Evidence B
Cisplatin (Platinol-Aq)

Theoretically, zinc might interfere with the therapeutic effects of cisplatin.
Animal research suggests that zinc stimulates tumor cell production of the protein metallothionein, which binds and inactivates cisplatin. It is not known whether zinc supplements or high dietary zinc intake can cause clinically significant interference with cisplatin therapy. Cisplatin might also increase zinc excretion.

Likelihood Possible Evidence D
Integrase Inhibitors

Theoretically, taking zinc along with integrase inhibitors might decrease the levels and clinical effects of these drugs.
Zinc is a divalent cation. Pharmacokinetic studies have shown that other divalent cations such as calcium and iron can decrease blood levels of the integrase inhibitor dolutegravir through chelation.

Likelihood Possible Evidence D
Penicillamine (Cuprimine, Depen)

Zinc might reduce the levels and clinical effects of penicillamine.
By forming an insoluble complex with penicillamine, zinc interferes with penicillamine absorption and activity. Zinc supplements reduce the efficacy of low-dose penicillamine (0.5-1 gram/day), but do not seem to affect higher doses (1-2.75 gram/day), provided dosing times are separated. Advise patients to take zinc and penicillamine at least 2 hours apart.

Likelihood Probable Evidence B
Quinolone Antibiotics

Zinc can decrease the levels and clinical effects of quinolones antibiotics.
Quinolones form complexes with zinc in the gastrointestinal tract, reducing absorption of both the quinolone and zinc if taken at the same time. Advise patients to take these drugs at least 2 hours before, or 4-6 hours after, zinc supplements.

Likelihood Probable Evidence B
Ritonavir (Norvir)

Zinc modestly reduces levels of ritonavir.
Clinical research shows that zinc might reduce serum ritonavir levels by chelating with ritonavir in the gut and preventing its absorption. In patients with HIV, ritonavir is taken with atazanavir to prevent the metabolism and increase the effects of atazanavir. A pharmacokinetic study shows that, in patients being treated with atazanavir/ritonavir, co-administration of zinc sulfate (Solvazinc tablets) 125 mg as a single dose or as multiple daily doses for 2 weeks reduces plasma levels of ritonavir by about 16%. However, atazanavir levels still remains high enough to prevent HIV virus replication. Therefore, the decrease in ritonavir levels is not likely to be clinically significant.

Likelihood Probable Evidence B
Tetracycline Antibiotics

Zinc might reduce levels of tetracycline antibiotics.
Tetracyclines form complexes with zinc in the gastrointestinal tract, which can reduce absorption of both the tetracycline and zinc when taken at the same time. Taking zinc sulfate 200 mg with tetracycline reduces absorption of the antibiotic by 30% to 40%. Demeclocycline and minocycline cause a similar interaction. However, doxycycline does not seem to interact significantly with zinc. Advise patients to take tetracyclines at least 2 hours before, or 4-6 hours after, zinc supplements to avoid any interactions.

Likelihood Probable Evidence B
Amiloride (Midamor)

Amiloride can modestly reduce zinc excretion and increase zinc levels.
Clinical research shows that amiloride can reduce urinary zinc excretion, especially at doses of 10 mg per day or more. This zinc-sparing effect can help to counteract zinc losses caused by thiazide diuretics, but it is unlikely to cause zinc toxicity at usual amiloride doses. The other potassium-sparing diuretics, spironolactone (Aldactone) and triamterene (Dyrenium), do not seem to have a zinc-sparing effect.

Likelihood Probable Evidence B
Atazanavir (Reyataz)

Zinc modestly reduces levels of atazanavir, although this effect does not seem to be clinically significant.
Clinical research shows that zinc might decrease serum atazanavir levels by chelating with atazanavir in the gut and preventing its absorption. Although a single dose of zinc sulfate (Solvazinc tablets) 125 mg orally does not affect atazanavir concentrations in patients being treated with atazanavir/ritonavir, co-administration of zinc sulfate 125 mg daily for 2 weeks reduces plasma levels of atazanavir by about 22% in these patients. However, despite this decrease, atazanavir levels still remain at high enough concentrations for the prevention of HIV virus replication.

Likelihood Probable Evidence B
Zinc full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Elderberry Zinc Immune Support Syrup, from the product label.

MegaFood

See all MegaFood products
Name
MegaFood
Street Address
PO Box 5244
City
Manchester
State
NH
ZipCode
03108
Phone Number
800.848.2542
Web Address
megafood.com
Pharmacist Counseling Corner

Elderberry Zinc Immune Support Syrup by MegaFood: Common Questions

Does Elderberry Zinc Immune Support Syrup by MegaFood interact with any medications?
Yes. Based on its ingredients, Elderberry Zinc Immune Support Syrup has a known interaction with 952 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Elderberry Zinc Immune Support Syrup contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this syrup if I'm pregnant or breastfeeding?
Zinc is rated likely safe during pregnancy and lactation, but elderberry safety data is not reliable enough — the facts advise avoiding elderberry supplements during both. Aronia berry data is not on file. Talk with your doctor or pharmacist for personalized advice on whether this product is right for you.
What's the difference between zinc, elderberry, and aronia berry in this syrup?
Zinc is a mineral with solid evidence for zinc deficiency and likely effectiveness for Wilson disease. Elderberry and aronia berry are fruit extracts used traditionally for immune support, but the evidence showing they work for specific conditions isn't well established. All three are included here to create a multiingredient immune-support formula.
What side effects might I experience from the zinc in this product?
At recommended doses below 40 mg daily, zinc is generally well tolerated. The most common side effects are abdominal cramps, diarrhea, metallic taste, nausea, and vomiting — all dose-related and usually mild. Taking it with food may help reduce stomach upset.
Does this syrup really work for colds and the flu?
Elderberry is used traditionally for respiratory infections, but our data shows insufficient evidence to rate whether it actually works for these conditions — meaning we don't have solid proof it helps. Zinc is effective for zinc deficiency but is only possibly effective for other uses. Talk with your doctor about what's proven for your specific health concern.
Is this safe to take long-term?
Zinc is generally safe in recommended amounts below 40 mg daily, but long-term high-dose zinc raises concern for copper deficiency. Elderberry made from ripe, cooked fruit is well tolerated; aronia berry is generally well tolerated as a food, though concentrated supplements are less studied. For long-term use, check with your doctor or pharmacist.
Can I take this if I'm on blood thinners?
Aronia berry in this product theoretically increases the risk of bleeding when taken with anticoagulant or antiplatelet drugs. Before you start this syrup, check with your own doctor or pharmacist if you take blood thinners — they may need to monitor you more closely or adjust your care.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Elderberry Zinc Immune Support Syrup label
Go deeper

The Full Monographs Behind Elderberry Zinc Immune Support Syrup’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Zinc

Interacts with 67 drugs

Zinc is an essential mineral that your body needs for immune function, wound healing, taste, and smell. Most people get enough from food, but supplements can help correct or prevent a defici...

Read the full Zinc monograph → Herb & supplement monograph

Elderberry

Interacts with 121 drugs

Elderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu symptoms, but the evidence is limited and n...

Read the full Elderberry monograph → Herb & supplement monograph

Chokeberry

Interacts with 811 drugs

Chokeberry (aronia) is a dark berry rich in antioxidants called polyphenols, and it's widely eaten as juice, jam, and supplements. Early research hints it may support heart health, blood pre...

Read the full Chokeberry monograph →
Sources

Sources & How We Checked

Elderberry Zinc Immune Support Syrup's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 102 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Zinc 88 references
  1. Barceloux DG. Zinc. J Toxicol Clin Toxicol 1999;37:279-92.
  2. Eby GA, Davis DR, Halcomb WW. Reduction in duration of common colds by zinc gluconate lozenges in a double-blind study. Antimicrob Agents Chemother 1984;25:20-4. DOI
  3. Smith DS, Helzner EC, Nuttall CE Jr, et al. Failure of zinc gluconate in treatment of acute upper respiratory tract infections. Antimicrob Agents Chemother 1989;33:646-8. PubMed
  4. Blondeau JM. Expanded activity and utility of the new fluoroquinolones: a review. Clin Ther 1999;21:3-40. PubMed
  5. Reyes AJ, Olhaberry JV, Leary WP, et al. Urinary zinc excretion, diuretics, zinc deficiency and some side-effects of diuretics. S Afr Med J 1983;64:936-41.
  6. Kugelmas M. Preliminary observation: oral zinc sulfate replacement is effective in treating muscle cramps in cirrhotic patients. J Am Coll Nutr 2000;19:13-5. PubMed
  7. Hebel SK, ed. Drug Facts and Comparisons. 52nd ed. St. Louis: Facts and Comparisons, 1998.
  8. Chan S, Gerson B, Subramaniam S. The role of copper, molybdenum, selenium, and zinc in nutrition and health. Clin Lab Med 1998;18:673-85. DOI
  9. Brewer GJ, Yuzbasiyan-Gurkan V, Johnson V, et al. Treatment of Wilson's disease with zinc: XI. Interaction with other anticopper agents. J Am Coll Nutr 1993;12:26-30. PubMed
  10. Fosmire GJ. Zinc toxicity. Am J Clin Nutr 1990;51:225-7.
  11. Lomaestro BM, Bailie GR. Absorption interactions with fluoroquinolones. 1995 update. Drug Saf 1995;12:314-33. PubMed
  12. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  13. Seelig MS. Auto-immune complications of D-penicillamine - A possible result of zinc and magnesium depletion and of pyridoxine inactivation. J Am Coll Nutr 1982;1:207-14. PubMed
  14. Neuvonen PJ. Interactions with the absorption of tetracyclines. Drugs 1976;11:45-54.. PubMed
  15. Hirt M, Nobel S, Barron E. Zinc nasal gel for the treatment of common cold symptoms: A double-blind, placebo-controlled trial. Ear Nose Throat J 2000;79:778-82.. DOI
  16. Simkin PA. Oral zinc sulphate in rheumatoid arthritis. Lancet 1976;2:539-42. PubMed
  17. Wray D. A double-blind trial of systemic zinc sulfate in recurrent aphthous stomatitis. Oral Surg Oral Med Oral Pathol 1982;53:469-72. PubMed
  18. Douglas RM, Miles HB, Moore BW, et al. Failure of effervescent zinc acetate lozenges to alter the course of upper respiratory tract infections in Australian adults. Antimicrob Agents Chemother 1987;31:1263-5. PubMed
  19. Lagiou P, Wuu J, Trichopoulou A, et al. Diet and benign prostatic hyperplasia: a study in Greece. Urology 1999;54:284-90. PubMed
  20. Ewing CI, Gibbs AC, Ashcroft C, David TJ. Failure of oral zinc supplementation in atopic eczema. Eur J Clin Nutr 1991;45:507-10.
  21. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  22. Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss. AREDS report no. 8. Arch Oph
  23. Greenberg JE, Lynn M, Kirsner RS, et al. Mucocutaneous pigmented macule as a result of zinc deposition. J Cutan Pathol 2002;29:613-5. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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