Fenugreek 1,350 mg Ingredients & Drug Interactions
by Nutricost
What is this page for?
First and foremost: checking Fenugreek 1,350 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Fenugreek 1,350 mg is a dietary supplement by Nutricost with 1 active ingredient. Its ingredients are commonly taken for blood sugar control, boosting breast milk supply, high cholesterol.Based on those ingredients, 389 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Fenugreek, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Fenugreek 1,350 mg by Nutricost
Ask about any prescription or over-the-counter medication and we check it for interactions with Fenugreek 1,350 mg by Nutricost — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Fenugreek 1,350 mg by Nutricost
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: fenugreek seed powder at 1,350 mg per capsule. Fenugreek is an herb traditionally used to support sexual function, menstrual comfort, and blood sugar control in people with type 2 diabetes.
The capsule also contains inactive ingredients — gelatin, microcrystalline cellulose, magnesium stearate, olive oil, and silicon dioxide — which are fillers and binders that hold the capsule together.
Does it work?
Moderate evidence
The evidence we hold shows fenugreek is possibly effective for sexual dysfunction and sexual arousal, and possibly effective for dysmenorrhea (painful periods) and diabetes management. That means there's some clinical support, but the evidence isn't airtight — more research would help us be more confident.
If you're considering it for one of these reasons, talk with your pharmacist or doctor about whether it makes sense for you.
How safe is it?
Well-documented data
Fenugreek is generally well tolerated at food doses, but supplement amounts can cause side effects in some people. The most common are stomach trouble — abdominal pain, bloating, diarrhea, indigestion, gas, and nausea — and rarely, low blood sugar (hypoglycemia).
Serious allergic reactions, though rare, are possible and may include severe swelling, trouble breathing, or shock. During pregnancy, avoid medicinal amounts of fenugreek because it may affect the uterus.
If you take it while pregnant or right before delivery, your newborn may develop an unusual body odor that could be mistaken for maple syrup urine disease — this doesn't seem to cause lasting harm, but it's worth knowing. If you're breastfeeding and want to use fenugreek to boost milk supply, the evidence is limited, so talk with your provider first before starting.
Meds to double-check
Moderate interaction found
Before taking Nutricost Fenugreek, double-check with your pharmacist if you take blood thinners like warfarin, antiplatelet drugs like clopidogrel, diabetes medications, theophylline, phenytoin, metoprolol, or sildenafil. Fenugreek has documented Moderate interactions with all of these and may change how they work or increase side effects.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
Fenugreek may help with sexual function, period pain, or blood sugar control, but it's not right for everyone and interacts with several common medications. If you take blood thinners, diabetes drugs, seizure or asthma medications, or sildenafil, check with your pharmacist before starting.
Avoid it during pregnancy, and don't use it without talking to your doctor if you're breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Fenugreek 1,350 mg, straight from the product label.
| Brand | Nutricost |
|---|---|
| Barcode (UPC) | 702669931489 |
| Net contents | 240 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jul 25, 2024 |
| DSLD ID | 306217 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Fenugreek 1,350 mg by Nutricost, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Fenugreek, Powder | 1350 mg | -- |
Other ingredients: Gelatin, Microcrystalline Cellulose, Magnesium Stearate, Olive Oil, Pure, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use: as a dietary supplement, take 2 capsules daily with 8-12 oz of water or as directed by your healthcare professional.
Formulation
Third party tested
Non-GMO Gluten-free
Made and quality tested in the USA with globally sourced ingredients.
Non-GMO product
Precautions
Warning: for healthy individuals 18 years and older. Keep out of reach of children.
Consult a healthcare professional prior to use pregnant or nursing, taking medication, or have a medical condition.
Do not use if safety seal is broken or missing.
Storage
Notice: store in a cool, dry place.
Formula
Fenugreek 1,350mg per serving
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
Nutricost Quality Guaranteed Third party tested GMP Compliant Facility
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Fenugreek 1,350 mg by Nutricost label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Fenugreek 1,350 mg by Nutricost
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.
Fenugreek, Powder
Interacts with389 drugs
Fenugreek is a common kitchen spice that is also taken as a supplement, mainly for blood sugar, cholesterol, and to support breast milk production. So...
Fenugreek, Powder monograph & interactionsOther (inactive) ingredients: Gelatin, Microcrystalline Cellulose, Magnesium Stearate, Olive Oil, Pure, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Fenugreek 1,350 mg by Nutricost Drug Interactions
HelloPharmacist Interaction Report
Nutricost Fenugreek 1,350 mg has documented interactions with multiple medication types.
The most serious concern is with blood thinners (anticoagulants) and antiplatelet drugs — fenugreek may have additive effects, meaning it could increase bleeding risk when combined with these medications. This applies to both warfarin (Coumadin) and drugs like clopidogrel (Plavix).
Read the full breakdown — every affected drug type, severity by severity
Fenugreek also interacts with diabetes medications at a Moderate severity level. Because fenugreek can lower blood glucose (blood sugar), taking it alongside diabetes drugs may cause blood sugar to drop too far.
Additionally, it may reduce how well theophylline (used for asthma and COPD) and phenytoin (an anti-seizure medication) work in your body — animal studies show meaningful decreases in drug levels. It can also have additive blood pressure-lowering effects with metoprolol and may reduce the effectiveness of sildenafil (Viagra).
All documented interactions span 386 individual medications.
Run your exact medications through the checker on this page before you start fenugreek, especially if you take blood thinners, diabetes drugs, or seizure or asthma medications.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Fenugreek 1,350 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Fenugreek 1,350 mg interact with 389 drugs. Click any drug to see the details.
1 of the 1 ingredient in Fenugreek 1,350 mg interact with drugs. Each result below shows which ingredient is responsible. Fenugreek, Powder
AbciximabReoPro
How Abciximab interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek, Powder + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Acetaminophen, Ibuprofen interactionAcetohexamideDymelor
How Acetohexamide interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek, Powder + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek, Powder + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek, Powder + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek, Powder + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek, Powder + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Anisindione interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek, Powder + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Argatroban interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Aspirin interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionAspirin, ButalbitalAxotal
How Aspirin, Butalbital interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Aspirin, Butalbital interactionAspirin, Butalbital, CaffeineFiorinal
How Aspirin, Butalbital, Caffeine interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Aspirin, Butalbital, Caffeine interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Butalbital, Caffeine, PhenacetinMarnal
How Aspirin, Butalbital, Caffeine, Phenacetin interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Aspirin, Butalbital, Caffeine, Phenacetin interactionAspirin, CaffeineAnacin
How Aspirin, Caffeine interacts with Fenugreek 1,350 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Aspirin, Caffeine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Fenugreek 1,350 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Fenugreek, Powder
Anticoagulant/Antiplatelet Drugs
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Some of the constituents in fenugreek have antiplatelet effects in animal and in vitro research. However, common fenugreek products might not contain sufficient concentrations of these constituents for clinical effects. A clinical study in patients with coronary artery disease or diabetes shows that taking fenugreek seed powder 2.5 grams twice daily for 3 months does not affect platelet aggregation, fibrinolytic activity, or fibrinogen levels .
Antidiabetes Drugs
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Clinical research shows that fenugreek seed can reduce fasting blood glucose and 2-hour postprandial glucose levels in adults with type 2 diabetes.
Clopidogrel (Plavix)
Theoretically, fenugreek seed might alter the clinical effects of clopidogrel by inhibiting its conversion to the active form.
Animal research shows that fenugreek seed 200 mg/kg daily for 14 days increases the maximum serum concentration of clopidogrel by 21%. It is unclear how this affects the pharmacokinetics of the active metabolite of clopidogrel; however, this study found that concomitant use of fenugreek seed and clopidogrel prolonged bleeding time by an additional 11%.
Metoprolol (Toprol)
Theoretically, fenugreek seed might have additive hypotensive effects when used with metoprolol.
Animal research shows that fenugreek seed 300 mg/kg daily for 2 weeks decreases systolic and diastolic blood pressure by 9% and 11%, respectively, when administered alone, and by 15% and 22%, respectively, when given with metoprolol 10 mg/kg.
Phenytoin (Dilantin)
Theoretically, fenugreek might decrease plasma levels of phenytoin.
Animal research shows that taking fenugreek seeds for 1 week decreases maximum concentrations and the area under the curve of a single dose of phenytoin by 44% and 72%, respectively. This seems to be related to increased clearance. So far, this interaction has not been reported in humans.
Sildenafil (Viagra)
Theoretically, concurrent use of sildenafil and fenugreek might reduce levels and therapeutic effects of sildenafil.
Animal research shows that taking fenugreek seeds for 1 week reduces maximum concentrations and the area under the curve of a single dose of sildenafil by 27% and 48%, respectively. So far, this interaction has not been reported in humans.
Theophylline
Theoretically, fenugreek may reduce the levels and clinical effects of theophylline.
Animal research shows that fenugreek 50 grams daily for 7 days reduces the maximum serum concentration (Cmax) of theophylline by 28% and the area under the plasma drug concentration-time curve (AUC) by 22%.
Warfarin (Coumadin)
Theoretically, fenugreek might have additive effects with warfarin and increase the international normalized ratio (INR).
Some fenugreek constituents have antiplatelet effects, although these might not be present in concentrations that are clinically significant. In one case report, a patient taking warfarin experienced an increased INR when starting to take fenugreek in combination with boldo.
Antihypertensive Drugs
Fenugreek may also have an additive effect on blood pressure-lowering medications. Studies on animals have shown that fenugreek seed can decrease both systolic and diastolic blood pressure by up to 22% when combined with metoprolol. Therefore, it is essential to monitor your blood pressure regularly if you are taking fenugreek and metoprolol together or any other antihypertensive drugs.
Brand information
Manufacturer and brand details for Fenugreek 1,350 mg, from the product label.
Nutricost
See all Nutricost products- Name
- Nutricost
- Street Address
- 351 E 1750 N
- City
- Vineyard
- State
- UT
- ZipCode
- 84059
- Phone Number
- (866) 438-3694
- Web Address
- www.nutricost.com
Fenugreek 1,350 mg by Nutricost: Common Questions
Does Fenugreek 1,350 mg by Nutricost interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will fenugreek help me if I have diabetes?
What side effects might I get from this?
Is it safe to take fenugreek while I'm pregnant?
Can I use fenugreek to boost my milk supply if I'm breastfeeding?
Does fenugreek work for sexual function?
Will fenugreek interfere with my blood thinner?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Fenugreek 1,350 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Fenugreek 1,350 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Fenugreek 1,350 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 30 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Fenugreek 30 references
- Madar Z, Thorne R. Dietary fiber. Prog Food Nutr Sci 1987;11:153-74.
- Sharma RD, Raghuram TC, Rao NS. Effect of fenugreek seeds on blood glucose and serum lipids in type I diabetes. Eur J Clin Nutr 1990;44:301-6.
- Patil SP, Niphadkar PV, Bapat MM. Allergy to fenugreek (Trigonella foenum graecum). Ann Allergy Asthma Immunol 1997;78:297-300. PubMed
- Lambert J, Cormier J. Potential interaction between warfarin and boldo-fenugreek. Pharmacotherapy 2001;21:509-12. PubMed
- Bordia A, Verma SK, Srivastava KC. Effect of ginger (Zingiber officinale Rosc.) and fenugreek (Trigonella foenumgraecum L.) on blood lipids, blood sugar and platelet aggregation in patients with coronary artery disease. Prostaglandins Leukot Essent Fatty PubMed
- Yalcin SS, Tekinalp G, Ozalp I. Peculiar odor of traditional food and maple syrup urine disease. Pediatr Int 1999;41:108-9. PubMed
- Sewell AC, Mosandl A, Bohles H. False diagnosis of maple syrup urine disease owing to ingestion of herbal tea. N Engl J Med 1999;341:769.. PubMed
- Abdo MS, al-Kafawi AA. Experimental studies on the effect of Trigonella foenum-graecum (abstract). Planta Med 1969;17:14-8.
- Gupta A, Gupta R, Lal B. Effect of Trigonella foenum-graecum (fenugreek) seeds on glycaemic control and insulin resistance in type 2 diabetes mellitus: a double blind placebo controlled study. J Assoc Physicians India 2001;49:1057-61.
- Gabay MP. Galactogogues: medications that induce lactation. J Hum Lact 2002;18:274-9. PubMed
- Chevassus H, Gaillard JB, Farret A, et al. A fenugreek seed extract selectively reduces spontaneous fat intake in overweight subjects. Eur J Clin Pharmacol 2010;66(5):449-55. PubMed
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