Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Organic Fermented Broccoli Sprouts Ingredients & Drug Interactions

by Dr. Mercola

Organic Fermented Broccoli Sprouts label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Organic Fermented Broccoli Sprouts against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Organic Fermented Broccoli Sprouts is a dietary supplement by Dr. Mercola with 2 active ingredients. Its ingredients are commonly taken for general nutrition and antioxidant support, heart and digestive health, detoxification support.Based on those ingredients, 187 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Broccoli, Fermented. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Organic Fermented Broccoli Sprouts by Dr. Mercola

Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Fermented Broccoli Sprouts by Dr. Mercola — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Organic Fermented Broccoli Sprouts by Dr. Mercola

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • “Broccoli” is listed as a grouped ingredient — the label gives one combined amount (100 mg) without saying how much of each component you get.

This product has three active ingredients: glucoraphanin and myrosinase, plus fermented broccoli. The fermented broccoli is the source of glucosinolates, compounds that give broccoli its potential health effects.

You'll also find two inactive ingredients — rice hull and pullulan (a thickener used in capsules).

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Broccoli's overall clinical evidence instead.

Moderate

Some clinical evidence supports Broccoli for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Colorectal cancer — rated "Possibly Effective" (Natural Medicines).

The data shows fermented broccoli is possibly effective for colorectal cancer prevention. For bladder cancer, breast cancer, fibromyalgia, and gastric cancer, the evidence is too thin right now to say whether it works — that doesn't mean it doesn't; we just don't have reliable studies to draw on yet.

The evidence, ingredient by ingredient Broccoli

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Broccoli as a regular food is safe for most people, but concentrated supplements like this one are less studied, so caution is warranted unless your doctor gives the okay. The main side effects reported with broccoli sprout extracts are loose stools, diarrhea, belly pain, and cramping — especially at higher doses.

Skin contact has occasionally caused allergic reactions (contact dermatitis) in sensitive people. The product is rated likely safe in pregnancy and lactation, though concentrated extracts are still less well understood than whole broccoli as food.

Side effects, ingredient by ingredient Broccoli

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Broccoli.
  • The most serious interaction on file is rated Moderate.
  • For scale: 187 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, check whether you take any drugs metabolized by CYP2A6 (which broccoli may reduce by a large margin) or CYP1A2 (which it may reduce more modestly). These are Moderate-severity interactions.

Your pharmacist can help identify your medications in these categories — don't start without confirming it's safe for your regimen.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

If you're interested in broccoli sprouts for colorectal cancer support and don't take medications processed through CYP1A2 or CYP2A6 enzymes, this is worth a conversation with your pharmacist. Anyone on medications metabolized by those liver pathways should check their specific drugs before starting.

Talk to us or your doctor if you have a history of stomach upset or if you're pregnant — the data supports safety, but concentrated supplements warrant personalized guidance.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Fermented Broccoli Sprouts, straight from the product label.

Brand Dr. Mercola
Barcode (UPC) 813006017763
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Jan 23, 2025
DSLD ID 327114
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Organic
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Fermented Broccoli Sprouts by Dr. Mercola, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
813006017763
IngredientAmount% DV
Glucoraphanin350 mcg--
Myrosinase105 mcg--
Broccoli, Fermented400 mg--
Broccoli100 mg--

Other ingredients: Rice hull, Pullulan

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Adults, as a dietary supplement, take one (1) capsule daily.

Precautions

Keep out of reach of children.

Do not use if safety seal is broken.

If you are nursing, pregnant, taking medication or have a medical condition, consult your physician before taking this product.

Seals/Symbols

USDA Organic

FDA Statement of Identity

Dietary Supplement

Formulation

Certified Organic by: Quality Assurance International

General Statements

Providing quality products since 2001.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Organic Fermented Broccoli Sprouts by Dr. Mercola label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Organic Fermented Broccoli Sprouts label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Organic Fermented Broccoli Sprouts by Dr. Mercola

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Broccoli, Fermented

Interacts with
187 drugs
400 mg per serving Form: Brassica oleracea, Fermented

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for...

Broccoli, Fermented monograph & interactions

Broccoli

Interacts with
187 drugs
100 mg per serving Form: Brassica oleracea, Brassica oleracea

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for...

Broccoli monograph & interactions
  • › Glucoraphanin
  • › Myrosinase

Other (inactive) ingredients: Rice hull, Pullulan. These complete the product’s ingredient list but are not active constituents.

Interaction report

Organic Fermented Broccoli Sprouts by Dr. Mercola Drug Interactions

Want to check YOUR meds against Organic Fermented Broccoli Sprouts?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
187Drugs
187 Moderate

Ingredients driving the most interactions

Broccoli, Fermented 187

Individual Drug Interactions

The ingredients in Organic Fermented Broccoli Sprouts interact with 187 drugs. Click any drug to see the details.

1 of the 2 ingredients in Organic Fermented Broccoli Sprouts interact with drugs. Each result below shows which ingredient is responsible. Broccoli, Fermented

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Fermented Broccoli Sprouts with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Broccoli, Fermented2 drug types · 187 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Pharmacokinetic research in humans shows that eating 500 grams of fresh broccoli daily for 6-12 days can increase CYP1A2 activity by 10% to 200%. Induction of CYP1A2 activity by broccoli is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP2A6.
Pharmacokinetic research in humans shows that eating 500 grams of broccoli daily for 6 days increases CYP2A6 activity by 135% to 550%. Induction of CYP2A6 activity is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
Broccoli, Fermented full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Organic Fermented Broccoli Sprouts, from the product label.

Dr. Mercola

See all Dr. Mercola products
Name
NHP
Street Address
125 SW 3rd Place
City
Cape Coral
State
FL
ZipCode
33991
Phone Number
(877) 985-2696
Pharmacist Counseling Corner

Organic Fermented Broccoli Sprouts by Dr. Mercola: Common Questions

Does Organic Fermented Broccoli Sprouts by Dr. Mercola interact with any medications?
Yes. Based on its ingredients, Organic Fermented Broccoli Sprouts has a known interaction with 187 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Fermented Broccoli Sprouts contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is glucoraphanin, and why is it in this supplement?
Glucoraphanin is a compound found naturally in broccoli. It's one of the three active ingredients in this product, though we don't have specific interaction data on file for it alone. It's included because broccoli — including its fermented form — contains glucosinolates, which are the compounds responsible for how broccoli affects your liver enzymes and may support health.
Can I take this if I have a sensitive stomach?
Broccoli sprout extracts have been reported to cause loose stools, diarrhea, belly pain, and cramping, especially at higher doses. If you already have a sensitive stomach or digestive issues, mention this to your pharmacist or doctor before starting — they can help you decide whether it's right for you or suggest a dose that works better.
Is this safe during pregnancy or while breastfeeding?
The product is rated likely safe during pregnancy and lactation. That said, concentrated broccoli supplements are less well studied than eating broccoli as a regular food. Talk with your doctor or pharmacist about whether this specific supplement makes sense for your situation.
What does 'fermented' mean here, and does it change how the supplement works?
Fermentation is a process that breaks down the broccoli using beneficial bacteria or fungi. The facts we have don't specify how fermentation changes the product's effects compared to plain broccoli extract, so that's a good question to ask your pharmacist if you're curious about the differences.
Will this help me prevent cancer?
Fermented broccoli is possibly effective for colorectal cancer based on the evidence we have. For bladder, breast, and gastric cancers, as well as fibromyalgia, the evidence is too limited to say either way right now. It's not a substitute for screening or treatment — talk with your doctor about how it might fit into your overall health plan.
What are the inactive ingredients, and will they bother me?
This capsule contains rice hull and pullulan. Pullulan is a common thickener and binder that's generally well tolerated. If you have sensitivities to these, let us know and we can help you find an alternative.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic Fermented Broccoli Sprouts is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Fermented Broccoli Sprouts label
Go deeper

The Full Monographs Behind Organic Fermented Broccoli Sprouts’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Broccoli

Interacts with 187 drugs

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for health benefits. Eating broccoli as food...

Read the full Broccoli monograph →
Sources

Sources & How We Checked

Organic Fermented Broccoli Sprouts's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Broccoli 5 references
  1. Kristal AR, Lampe JW. Brassica vegetables and prostate cancer risk: a review of the epidemiological evidence. Nutr Cancer 2002;42:1-9. PubMed
  2. Chakrabarti A, Prais L, Foulds IS. Allergic contact dermatitis to broccoli. Br J Dermatol 2003;148:172-3. PubMed
  3. Hakooz, N. and Hamdan, I. Effects of dietary broccoli on human in vivo caffeine metabolism: a pilot study on a group of Jordanian volunteers. Curr Drug Metab 2007;8(1):9-15. PubMed
  4. Kall MA, Vang O, Clausen J. Effects of dietary broccoli on human drug metabolising activity. Cancer Lett. 1997;114(1-2):169-70. PubMed
  5. Bauman JE, Hsu CH, Centuori S, et al. Randomized Crossover Trial Evaluating Detoxification of Tobacco Carcinogens by Broccoli Seed and Sprout Extract in Current Smokers. Cancers (Basel). 2022;14(9):2129. Published 2022 Apr 24. PubMed

See these in context on the Broccoli monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team