No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 3 of 12 ingredients. Check your meds →
Dietary supplement

Flo Ingredients & Drug Interactions

by OneBode

Capsule Category: Other Combinations
No known interaction
The interaction bottom line No known interaction

Flo is a dietary supplement by OneBode with 12 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Flo by OneBode

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 12 of its 12 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Flo contains 12 active ingredients, all digestive enzymes and supporting blends. The main ones we have safety data for are Lipase, Lactase, and proteolytic enzymes (Protease I and II) — each breaks down different nutrients so your body can absorb them.

Lactase specifically helps digest milk sugar; the others support general digestion. The product also includes several ingredients we don't have full data on: Amylase, Cellulase, Peptidase, Invertase, Maltase, HemiSEB™, a Digestive Support Food Blend, and an Immune and Digestive Support Probiotic Blend.

The inactive ingredients are purified beet fiber, plant-derived magnesium stearate, and a vegetable capsule.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • The label markets general wellness (“complete digestive support”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Lactose intolerance — rated "Effective" (Lactase) (Natural Medicines).

The only ingredient here with established effectiveness is Lactase, which is effective for lactose intolerance — the difficulty digesting milk sugar. For the other enzymes — Lipase and the proteases — evidence for digestive conditions like inflammatory bowel disease (IBD) and dyspepsia (indigestion) is insufficient; we simply don't have enough reliable studies to rate them.

We have no effectiveness data on file for the remaining ingredients in the blend.

The evidence, ingredient by ingredient Lipase Lactase Proteolytic Enzymes (proteases)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lipase, Lactase, and the proteases are generally well tolerated in adults. However, a thorough safety evaluation of supplemental lipase hasn't been done, and digestive upset or allergic reactions can occasionally occur with the proteases — occupational exposure to airborne proteases has rarely caused allergic rhinitis or asthma.

If you're pregnant, the data is sparse. Lactase is likely safe; Lipase has little pregnancy safety data, so use only if your doctor advises it.

The proteases should be avoided during pregnancy unless prescribed. During breastfeeding, Lactase is probably okay, but safety data for Lipase and the proteases is limited — check with your doctor or pharmacist first.

If you have serious digestive conditions, use Lipase only under medical guidance.

Side effects, ingredient by ingredient Lipase Lactase Proteolytic Enzymes (proteases)

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 3 matched ingredients has a documented medication interaction on file.

No interactions are documented for the ingredients we could check in Flo. Since we couldn't evaluate several of the ingredients, run your exact medications through the tool below just to be thorough.

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

Flo is a digestive enzyme blend most useful if you have lactose intolerance — Lactase is proven for that. If you're hoping to ease general digestion or other stomach issues, the evidence for the other enzymes isn't solid yet.

It's generally well tolerated, but if you're pregnant, breastfeeding, or have a serious digestive disorder, talk to your pharmacist or doctor before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 12 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 24, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Flo, straight from the product label.

Brand OneBode
Barcode (UPC) 014834001355
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Aug 24, 2012
DSLD ID 12769
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Flo by OneBode, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
30
UPC/BARCODE
014834001355
IngredientAmount% DV
Amylase12000 DU--
Lipase75 LU--
Lactase1200 LACU--
Cellulase300 CU--
Peptidase750 SEC--
Invertase162 INVU--
Maltase225 (0)DP--
Protease I47250 HUT--
Protease II9000 PU--
HemiSEB(TM)1650 HCO--
Digestive Support Food Blend69 mg--
Immune and Digestive Support Probiotic Blend1050000000 CFU--

Other ingredients: Purified beet fiber, plant derived magnesium stearate, Vegetable Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General

PRODUCT NO. T00135 LBL. 1131136

Brand IP Statement(s)

OneBode(TM) Flo combines the benefits of enzymes (100% non-animal) and stabilized probiotics for complete digestive support. A special blend of ten different types of active enzymes and five probiotic strains enhance the breakdown of fats, carbohydrates, and proteins into smaller absorbable nutrients that your body can absorb and use for overall health.

Suggested/Recommended/Usage/Directions

Recommended Use: As a dietary supplement, take 1 to 2 capsules with partially cooked meals and 3 capsules with fully cooked meals or as directed by a health professional.

Storage

STORE TIGHTLY CLOSED IN A COOL, DRY PLACE.

Formulation

Does not contain glandulars or pancreatic enzymes, genetically modified organisms, gluten, soy, or yeast.

Vegetarian Friendly

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Manufactured in a GMP facility.

whole-food nutrition for every day

daily.

probiotic enzyme digestive

FDA Statement of Identity

dietary supplement

See for yourself

Flo by OneBode label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Flo by OneBode

These are the 12 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Amylase

12000 DU per serving

Lipase

No known
interactions
75 LU per serving

Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy fo...

Lipase monograph & interactions

Lactase

No known
interactions
1200 LACU per serving

Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can red...

Lactase monograph & interactions

Cellulase

300 CU per serving

Peptidase

750 SEC per serving

Invertase

162 INVU per serving

Maltase

225 (0)DP per serving

Protease I

No known
interactions
47250 HUT per serving

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...

Protease I monograph & interactions

Protease II

No known
interactions
9000 PU per serving

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...

Protease II monograph & interactions

HemiSEB(TM)

1650 HCO per serving

Digestive Support Food Blend

69 mg per serving Form: Blackstrap Molasses, Ginger, Licorice Root DGL, Pine Nut

Immune and Digestive Support Probiotic Blend

1050000000 CFU per serving Form: DDS-1(TM) Lactobacillus acidophilus, Enterococcus faecium, Lactobacillus bulgaricus, Lactobacillus plantarum OM, Streptococcus thermophilus

Other (inactive) ingredients: Purified beet fiber, Plant derived magnesium stearate, Vegetable Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Flo by OneBode Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Flo. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Flo, from the product label.

OneBode

See all OneBode products
Name
OneBode
City
Chandler
State
AZ
ZipCode
85226
Phone Number
1 (888) 574-3341
Pharmacist Counseling Corner

Flo by OneBode: Common Questions

Does Flo by OneBode interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Flo. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Flo contains 12 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will Flo help if I'm lactose intolerant?
Yes — Lactase, one of the main ingredients, is proven effective for lactose intolerance. It breaks down milk sugar so you can digest dairy better.
What about using this for general indigestion or bloating?
The other enzymes in here — Lipase and the proteases — might help with digestion, but there isn't enough reliable evidence yet to say they work for indigestion or other digestive complaints. Lactase is the only one we have solid evidence for.
Is it safe if I'm pregnant?
There isn't enough data to know for sure. Lactase is probably okay, but Lipase has little pregnancy data — use only if your doctor says so. The proteases should be avoided during pregnancy unless prescribed. Talk to your doctor or pharmacist before you start.
Can I take this while breastfeeding?
Lactase is probably safe, but data on Lipase and the proteases while breastfeeding is limited. Check with your doctor or pharmacist first to be sure it's right for you.
Has Flo been tested for side effects?
No serious adverse effects have been reported in adults, though a full safety evaluation hasn't been done. Digestive upset or allergic reactions are rare but possible with the proteases. One case of allergic reaction to Lactase has been reported in a worker exposed to powdered form.
Does this interact with medications I'm taking?
No interactions are documented in our data for the ingredients we could check. Since we couldn't evaluate all of them, run your exact medications through the tool on this page to be safe.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Flo is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Flo label
Sources

Sources & How We Checked

Flo's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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