No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Formula 5 Lipase Ingredients & Drug Interactions

by NESS Nutritional Enzyme Support System

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Formula 5 Lipase is a dietary supplement by NESS Nutritional Enzyme Support System with 1 active ingredient. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Formula 5 Lipase by NESS Nutritional Enzyme Support System

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Formula 5 Lipase is a single-ingredient product: lipase, a digestive enzyme that breaks down fats in food. The capsule also contains plant fiber and water as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Lipase's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: optimize digestion of fat and systemic balance.
  • We looked for evidence on: Dyspepsia, Fat malabsorption, Pancreatic insufficiency, Steatorrhea.
  • The closest evidence on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia (Natural Medicines).

The evidence we hold on lipase for inflammatory bowel disease (IBD) and indigestion (dyspepsia) is insufficient — we can't say whether it works for these uses based on current data. For prematurity, the same is true.

If you're considering this for a specific condition, talk it over with your doctor or pharmacist to see whether it's a good fit for you.

The evidence, ingredient by ingredient Lipase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lipase is generally well tolerated in supplement form in adults, though a full safety evaluation hasn't been completed. If you have a serious digestive condition, use it only under medical guidance.

For pregnancy, there's little safety data on supplemental lipase — use it only if your doctor advises it. Breastfeeding safety hasn't been well studied either, so check with your healthcare provider first.

In premature infants given a recombinant form of lipase added to formula or breast milk, rare serious gastrointestinal problems have been reported, including abdominal distension, flatulence, constipation, colic, abdominal pain, gastroenteritis, vomiting, regurgitation, rectal bleeding, and a slightly higher rate of necrotizing enterocolitis (a serious bowel condition). This product is not intended for premature infants.

Side effects, ingredient by ingredient Lipase

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That said, it's always smart to run your exact medications through the tool on this page before you start any new supplement.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

Formula 5 Lipase is a straightforward digestive enzyme with no documented medication interactions. It's generally well tolerated, though the evidence for how well it works for indigestion or inflammatory bowel disease isn't established.

If you have a serious digestive condition or are pregnant or breastfeeding, talk with your doctor or pharmacist before starting it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Formula 5 Lipase, straight from the product label.

Brand NESS Nutritional Enzyme Support System
Barcode (UPC) 707636031513
Net contents 90 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jun 24, 2020
DSLD ID 221227
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Formula 5 Lipase by NESS Nutritional Enzyme Support System, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Vegetarian Capsule(s)
Maximum serving Sizes:
3 Vegetarian Capsule(s)
Servings per container
30
UPC/BARCODE
707636031513
IngredientAmount% DV
Lipase7.5 mg--

Other ingredients: Plant Fiber, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Formulated exclusively for healthcare professionals NESS Lipase helps optimize the digestion of fat, minimizing fat intolerance when taken with a meal or helps promote systemic balance when taken between meals.

Non-GMO

Vegetarian

GMP compliant

Contains No: aspartame, sugar, salt, gluten, artificial colors or flavors, dairy products, wheat, soy, yeast or corn proteins.

Precautions

Caution: If you are pregnant, nursing, have a serious medical condition, or take any medications, consult your physician before use.

Use only if tamper evident seal is unbroken

Keep out of reach of children.

Storage

Store tightly closed in a cool, dry place.

FDA Disclaimer Statement

These statement have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, mitigate, cure or prevent any disease.

General Statements

Nutritional enzyme support system

FDA Statement of Identity

Enzyme Supplement

Suggested/Recommended/Usage/Directions

Recommended Use: Take three (3) capsule at the beginning of each meal for digestive support or twice daily on an empty stomach for systemic support, or as directed by your healthcare professional.

See for yourself

Formula 5 Lipase by NESS Nutritional Enzyme Support System label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Formula 5 Lipase by NESS Nutritional Enzyme Support System

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Vegetarian Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Lipase

No known
interactions
7.5 mg per serving

Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy fo...

Lipase monograph & interactions

Other (inactive) ingredients: Plant Fiber, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Formula 5 Lipase by NESS Nutritional Enzyme Support System Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Formula 5 Lipase. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Formula 5 Lipase, from the product label.

NESS Nutritional Enzyme Support System

See all NESS Nutritional Enzyme Support System products
Name
Enzymes Inc.
City
Kansas City
State
MO
ZipCode
64153
Phone Number
1-800-637-7893
Web Address
www.nessenzymes.com
Pharmacist Counseling Corner

Formula 5 Lipase by NESS Nutritional Enzyme Support System: Common Questions

Does Formula 5 Lipase by NESS Nutritional Enzyme Support System interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Formula 5 Lipase. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Formula 5 Lipase contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is lipase safe to use while I'm pregnant?
There's little safety data on supplemental lipase in pregnancy. Talk with your doctor before taking it — they can help you decide whether it's right for you based on your situation.
Can I take this while breastfeeding?
Safety while breastfeeding hasn't been well studied. Check with your healthcare provider first to see whether it's okay for you and your baby.
What does lipase do?
Lipase is a digestive enzyme that breaks down fats in the food you eat. It's meant to support fat digestion.
Does this product work for indigestion?
The evidence we hold on lipase for indigestion (dyspepsia) is insufficient — we can't say whether it works for this use based on current data. Talk with your doctor about whether it's worth trying for your situation.
Are there any side effects?
No adverse effects have been reported in adults, though a thorough safety evaluation hasn't been done. If you develop any unusual symptoms after taking it, talk with your doctor or pharmacist.
What are the inactive ingredients?
The capsule contains plant fiber and water as inactive ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Formula 5 Lipase is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Formula 5 Lipase label
Go deeper

The Full Monographs Behind Formula 5 Lipase’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Formula 5 Lipase's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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