Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Forskolin Lean & Tone Ingredients & Drug Interactions

by BioGenetic Laboratories

Forskolin Lean & Tone label
See full label image
Capsule Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Forskolin Lean & Tone against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Forskolin Lean & Tone is a dietary supplement by BioGenetic Laboratories with 1 active ingredient. Its ingredients are commonly taken for weight management, asthma and breathing, high blood pressure.Based on those ingredients, 915 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are ForsLean Coleus forskohlii extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Forskolin Lean & Tone by BioGenetic Laboratories

Ask about any prescription or over-the-counter medication and we check it for interactions with Forskolin Lean & Tone by BioGenetic Laboratories — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.
Computed from our clinical databases

HelloPharmacist Scorecard of Forskolin Lean & Tone by BioGenetic Laboratories

Four independent checks of what is known — a summary of the available information, not a grade of the product itself.

Evidence for Intended Use
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The stated purpose hasn't been mapped to our evidence data yet.

Why this rating?
  • We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Ingredient Transparency
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.
Known Interaction Concern
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Coleus.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 916 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Safety Information
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Forskolin Lean & Tone, straight from the product label.

Brand BioGenetic Laboratories
Barcode (UPC) 083488005152
Net contents 60 Veggie Capsule(s)
Market status Off market
Date entered into DSLD Apr 23, 2020
DSLD ID 216841
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Forskolin Lean & Tone by BioGenetic Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
1 Vegetarian Capsule(s)
Servings per container
60
UPC/BARCODE
083488005152
IngredientAmount% DV
ForsLean Coleus forskohlii extract250 mg--

Other ingredients: Hypromellose, Vegetable Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Patented weight-loss potency!

It increases cAMP (Cyclic Adenosine Monophosphate) to help increase lean body tissue and break down fat tissue. ForsLean has been extensively tested for purity and potency. Forskolin Lean & Tone with ForsLean extract offers the only patented 10 and 20% extract with published studies showing a decrease in body fat and body weight and an increase in lean tissue.

The conclusion? ForsLean has been shown to increase important metabolism-boosting lean tissue as it reduces body fat, helping our bodies become more efficient fat-fighting machines. If your goal is to look leaner and more toned, Forskolin Lean & Tone with patented ForsLean may help you tip the scales in your favor so you can reach your goals faster.

12-Week clinical studies showed support for: Improved fat-burning metabolism Enhanced lean, toned muscle Decreased body fat Improved BMI

Stimulant free

Vegetarian

General Statements

Do you want a lean and toned body? This new breakthrough can be the key to both!

In one study, ForsLean subjects lost 4.02% of their total body weight while the placebo group actually gained weight (0.29%). In a subsequent 12-week, randomized, double-blind, placebo controlled study, ForsLean subjects lost 9.9 lbs of fat mass and gained 8.1 lbs of lean body mass (vs. fat loss of 1.1 lbs and gain of 3.45 lbs lean body mass for the placebo group).

Quality and results!

"ForsLean shifts the proportion between lean body mass and adipose, or fatty, tissue in favor of lean body mass, which improves overall health," explains N. Kalyanam, Ph.D, Sabinsa Corporation's president of Research and Development. "The effect can be measured by decreases in the waist/hip ratio and the body mass index."

Look for real ForsLean, listed by name, rather than a generic form of forskohlii to ensure quality and results.

Scientific references: Badmaev V, Majeed M, Conte A, Parker JE. (2002). Diterpene forskolin (Coleus forskohlii, Benth): A possible new compound for reduction of body weight by increasing lean body mass. NutraCos. March/April, 6-7 Asano Tsuguyoshi. (2001). Clinical report on root extract of perilla plant (Coleus forskohlii) ForsLean in reducing body fat. Asano Institute. Tokyo, Japan. Bhagwat, A.M. et al. (2004). A Randomized Double-Blind Clinical Trial to investigate the Efficacy and Safety of ForsLean in increasing Lean Body Mass Shri C.B. Patel Research Center for Chemistry and Biological Sciences, Mumbai, India Godard, M. P. et al. (2004). Body composition and hormonal adaptations associated with Forskolin consumption in overweight and obese Men. Obesity Res. 13: 1335-1343 Kamath, M.S. et al. (2004). Efficacy and safety of ForsLean in increasing Lean Body Mass. Department of Ayurvedic Medicine, Kasturba Medical College, Manipal, India

Facebook Come join the thousands of others who are enjoying their new, thinner, lighter, and more energetic bodies, and see them sharing their successful weight-loss stories: Facebook.com/BioGeneticLabs

New look

30 Day supply

Free diet plan inside

(Stock Symbol: FTLF)

Formula

Coleus forskohlii is an herb originating from India. Yet not all Coleus forskohliis are the same. Recent breakthroughs credit a special extract as the key to looking leaner. Here's the skinny on how it works and why this patented extract may help you sculpt a leaner, sleeker body: ForsLean is the proprietary extract of Coleus forskohlli's active ingredient, Forskolin.

With patented ForsLean including 20% Forskolin

ForsLean With patented 10 and 20 % Forskolin 250 mg per serving

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

ForsLean is a proprietary ingredient, patented for use and composition in promoting lean body mass, reduction of adipose tissue (fat) and weight loss (US Patent # 5,804,596).

ForsLean is a registered trademark of Sabinsa Corporation. US Patent #5,804,596

2017 FitLife Brands, Inc.

Precautions

Individual results may and will differ. Always consult a physician prior to any diet or exercise program.

Notice: Keep out of reach of children.

For adult use only. Do not exceed recommended dose.

Consult a physician prior to using this product if you are pregnant, nursing, taking medication of have a medical condition.

Discontinue use two weeks prior to surgery. Seek the advice of a health care professional before beginning any supplement or exercise program.

If you or your doctor has any questions about this product, please call 1-888-752-6615. Improper use of this product will not improve results and is not advised. Only follow a reduced calorie diet under the supervision of a doctor.

Consult with your primary physician prior to use if you have any pre-existing medical conditions including high blood pressure, thyroid problems, nervous disorders, or if you are using MAO inhibitors or taking any prescription drugs.

Do not use if packaging has been tampered with.

California residents Warning: Cancer and reproductive harm - www.P65Warnings.ca.gov/food

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions for use: As a dietary supplement, take one serving (1 veggie capsule) twice daily with a full glass of water, preferably on an empty stomach, about 30 minutes prior to meals. Take one serving upon waking (before breakfast), and take a second serving between lunch and dinner. Please read the entire label carefully before use, and follow the diet plan (included free).

Storage

Store in a cool, dry place. Avoid excessive heat.

Seals/Symbols

Made in the USA Made in the USA from International and domestic ingredients.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Forskolin Lean & Tone by BioGenetic Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Forskolin Lean & Tone label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Forskolin Lean & Tone by BioGenetic Laboratories

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

ForsLean Coleus forskohlii extract

Interacts with
915 drugs
250 mg per serving Form: Forskolin, Forskolin

Coleus is a plant from the mint family whose root contains a compound called forskolin, often marketed for weight loss, asthma, and heart health. Whil...

ForsLean Coleus forskohlii extract monograph & interactions

Other (inactive) ingredients: Hypromellose, Vegetable Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Forskolin Lean & Tone by BioGenetic Laboratories Drug Interactions

Forskolin Lean & Tone contains a single active ingredient, and it has known interactions with 915 medications. Here’s the picture, then you can look up your own drug.

Want to check YOUR meds against Forskolin Lean & Tone?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
915Drugs
29 Major 886 Moderate

Ingredients driving the most interactions

ForsLean Coleus forskohlii extract 915

Individual Drug Interactions

The ingredients in Forskolin Lean & Tone interact with 915 drugs. Click any drug to see the details.

1 of the 1 ingredient in Forskolin Lean & Tone interact with drugs. Each result below shows which ingredient is responsible. ForsLean Coleus forskohlii extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Forskolin Lean & Tone with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

ForsLean Coleus forskohlii extract7 drug types · 915 drugs

Calcium Channel Blockers

Theoretically, combining coleus with calcium channel blockers might increase the coronary vasodilatory effects.
Forskolin, a constituent of coleus, and calcium channel blockers both cause coronary vasodilatory effects.

Likelihood Probable Evidence B
Nitrates

Theoretically, combining coleus with nitrates might increase the coronary vasodilatory effects.
Forskolin, a constituent of coleus, and nitrates both cause coronary vasodilatory effects.

Likelihood Probable Evidence B
Anticoagulant/Antiplatelet Drugs

Theoretically, concomitant use of coleus and anticoagulant or antiplatelet drugs might increase the risk of bruising and bleeding.
In vitro and animal research shows that forskolin, a constituent of coleus, can inhibit platelet aggregation and adhesion.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, combining coleus with antihypertensive drugs might cause additive blood pressure lowering effects and increase the risk of hypotension.
Animal research shows that forskolin, a constituent of coleus, may lower blood pressure.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, taking coleus may affect drugs metabolized by CYP2C9 and increase the risk of adverse effects or reduce the effectiveness.
Research on the effect of coleus on CYP2C9 is conflicting. Some animal research shows that coleus extract can induce CYP2C9, while in vitro research shows that coleus can inhibit CYP2C9. Until more is known, advise patients that taking coleus might increase or decrease levels of drugs metabolized by CYP2C9.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, taking coleus might decrease serum levels of drugs metabolized by CYP3A4.
In vitro research shows that coleus can activate the nuclear receptor, pregnane X receptor (PXR), which results in increased expression of CYP3A4. Although the clinical significance of this is not known, use caution when considering concomitant use of coleus and other drugs affected by these enzymes.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, taking coleus may affect the metabolism of warfarin and increase the risk of adverse effects or reduce the effectiveness.
Some animal research shows that coleus extract can induce cytochrome P450 2C9 (CYP2C9), an enzyme that metabolizes warfarin. However, other in vitro research shows that coleus can inhibit CYP2C9. Theoretically, taking coleus with drugs metabolized by CYP2C9 might affect drug levels and the risk of adverse effects. Until more is known, advise patients that taking coleus might increase or decrease levels of warfarin.

Likelihood Possible Evidence D
ForsLean Coleus forskohlii extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Forskolin Lean & Tone, from the product label.

BioGenetic Laboratories

See all BioGenetic Laboratories products
Name
BioGenetic Laboratories A Division of FitLife Brands
Street Address
5214 South 136th Street
City
Omaha
State
NE
ZipCode
68137
Phone Number
1-888-752-6615
Web Address
BioGeneticLabs.com
Pharmacist Counseling Corner

Forskolin Lean & Tone by BioGenetic Laboratories: Common Questions

Does Forskolin Lean & Tone by BioGenetic Laboratories interact with any medications?
Yes. Based on its ingredients, Forskolin Lean & Tone has a known interaction with 915 medications, including 29 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Forskolin Lean & Tone contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Forskolin Lean & Tone is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Forskolin Lean & Tone label
Go deeper

The Full Monographs Behind Forskolin Lean & Tone’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Coleus

Interacts with 915 drugs

Coleus is a plant from the mint family whose root contains a compound called forskolin, often marketed for weight loss, asthma, and heart health. While early lab and small human studies are...

Read the full Coleus monograph →
Sources

Sources & How We Checked

Forskolin Lean & Tone's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Coleus 16 references
  1. Baumann G, Felix S, Sattelberger U, Klein G. Cardiovascular effects of forskolin (HL-362) in patients with idiopathic congestiv cardiomyopathy. A comparative study with dobutamine and sodium nitroprusside. J Cardiovasc Pharmacol 1990;16:93-100.
  2. Kramer W, Thormann J, Kindler M, Schlepper M. Effects of forskolin on left ventricular function in dilated cardiomyopathy. Arzneimittelforschung 1987;37:364-7.
  3. Bauer K, Dietersdorfer F, Kaspar S, et al. Pharmacodynamic effects of inhaled dry powder formulations of fenoterol and colforsin in asthma. Clin Pharmacol Ther 1993;53:76-83. PubMed
  4. Christenson JT, Thulesius O, Nazzal MM. The effect of forskolin on blood flow, platelet metabolism, aggregation and ATP release. Vasa 1995;24:56-61.
  5. Agarwal KC, Zielinski BA, Maitra RS. Significance of plasma adenosine in the antiplatelet activity of forskolin: potentiation by dipyridamole and dilazep. Thromb Haemost 1989;61:106-10. DOI
  6. Agarwal KC, Parks RE. Forskolin: a potential antimetastatic agent. Int J Cancer 1983;32:801-4. PubMed
  7. Almeida, F. C. and Lemonica, I. P. The toxic effects of Coleus barbatus B. on the different periods of pregnancy in rats. J Ethnopharmacol 2000;73(1-2):53-60. PubMed
  8. Ding, X. and Staudinger, J. L. Induction of drug metabolism by forskolin: the role of the pregnane X receptor and the protein kinase a signal transduction pathway. J Pharmacol Exp Ther 2005;312(2):849-856. PubMed
  9. Staudinger, J. L., Ding, X., and Lichti, K. Pregnane X receptor and natural products: beyond drug-drug interactions. Expert.Opin Drug Metab Toxicol 2006;2(6):847-857. PubMed
  10. van Hecke, E., Hindryckx, P., Geuns, J. M., and Devriese, E. Airborne contact dermatitis from coleus in a housewife. Contact Dermatitis 1991;25(2):128-129. PubMed
  11. Schlepper, M., Thormann, J., and Mitrovic, V. Cardiovascular effects of forskolin and phosphodiesterase-III inhibitors. Basic Res Cardiol 1989;84 Suppl 1:197-212. PubMed
  12. Dooms-Goossens, A., Borghijs, A., Degreef, H., Devriese, E. G., and Geuns, J. M. Airborne contact dermatitis to Coleus. Contact Dermatitis 1987;17(2):109-110. PubMed
  13. Lindner, E., Dohadwalla, A. N., and Bhattacharya, B. K. Positive inotropic and blood pressure lowering activity of a diterpene derivative isolated from Coleus forskohli: Forskolin. Arzneimittelforschung 1978;28(2):284-289.
  14. Loftus HL, Astell KJ, Mathai ML, et al. Coleus forskohlii Extract Supplementation in Conjunction with a Hypocaloric Diet Reduces the Risk Factors of Metabolic Syndrome in Overweight and Obese Subjects: A Randomized Controlled Trial. Nutrients. 2015;7(11): PubMed
  15. Yokotani K, Chiba T, Sato Y, et al. Hepatic cytochrome P450 mediates interaction between warfarin and Coleus forskohlii extract in vivo and in vitro. J Pharm Pharmacol. 2012;64(12):1793-801.
  16. Nishijima C, Chiba T, Sato Y, Umegaki K. Nationwide Online Survey Enables the Reevaluation of the Safety of Coleus forskohlii Extract Intake Based on the Adverse Event Frequencies. Nutrients. 2019;11(4). pii: E866. PubMed

See these in context on the Coleus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team