Interactions on record — worth a quick check against your medications. Based on 2 of 4 ingredients. Check your meds →
Dietary supplement

Fortify Optima Daily Probiotic 100 Billion Ingredients & Drug Interactions

by Nature's Way

Fortify Optima Daily Probiotic 100 Billion label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Fortify Optima Daily Probiotic 100 Billion against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Fortify Optima Daily Probiotic 100 Billion is a dietary supplement by Nature's Way with 4 active ingredients. Its ingredients are commonly taken for constipation and digestive health, source of prebiotic fiber (inulin), coffee substitute.Based on those ingredients, 2,108 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Gum Acacia Fiber, Chicory Root Fiber. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Fortify Optima Daily Probiotic 100 Billion by Nature's Way

Ask about any prescription or over-the-counter medication and we check it for interactions with Fortify Optima Daily Probiotic 100 Billion by Nature's Way — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Fortify Optima Daily Probiotic 100 Billion by Nature's Way

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 17 active ingredients.
  • “Bifidobacteria Blend” is a proprietary blend — the label doesn't break down how much of each component you get.
  • “Lactobacilli Blend” is a proprietary blend — the label doesn't break down how much of each component you get.
  • “Proprietary Plant-Based Prebiotic Blend” is a proprietary blend — the label gives one combined amount (75 mg) without saying how much of each component you get.

This product contains 17 active ingredients — a mix of probiotic bacterial strains and prebiotic fibers designed to support gut health. The live bacteria include several Lactobacillus species (casei, paracasei, acidophilus, brevis, rhamnosus, plantarum, salivarius, and gasseri) and Bifidobacterium species (animalis lactis, longum, and a general blend), along with Chicory Root Fiber and Gum Acacia Fiber to feed beneficial bacteria.

The inactive ingredients are cellulose, hypromellose, gellan gum, magnesium stearate, and silica — standard capsule binders and flow agents.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: digestive and immune health support.
  • We looked for evidence on: Abdominal pain, Antibiotic-associated diarrhea, Constipation, Diarrhea, Dyspepsia, Helicobacter pylori — and 4 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Helicobacter pylori, Irritable bowel syndrome (IBS).
  • Also on file: Chicory is rated "Insufficient Reliable Evidence To Rate" for Constipation, Dyspepsia.

Evidence for most conditions in this product is incomplete or insufficient. Lactobacillus acidophilus, one of the checked strains, is possibly effective for irritable bowel syndrome, Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis — though it's rated possibly ineffective for atopic disease.

The other strains we could check — Lactobacillus gasseri and Bifidobacterium longum — show insufficient evidence to rate their effectiveness for the conditions listed (including hay fever, asthma, and common cold). For Chicory Root Fiber, evidence is also insufficient across all listed uses.

The evidence base for most of these probiotics and prebiotics remains limited.

The evidence, ingredient by ingredient Chicory Gum Arabic

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus acidophilus and Bifidobacterium longum are generally well tolerated in healthy adults and children, though data are limited — check with your doctor before use. The most common side effects from probiotics are gastrointestinal: abdominal pain, bloating, flatulence, diarrhea, and burping — but these are uncommon.

Chicory Root Fiber commonly causes abdominal pain, belching, bloating, and flatulence; it may also trigger allergies in people sensitive to the ragweed family (Asteraceae). There is theoretical concern that live probiotic organisms could, in rare cases, cause infection in severely ill or immune-compromised patients; most documented cases involve translocation of bacteria from other body sites.

Pregnancy and lactation safety data are not on file for most of the ingredients in this product. Chicory should be avoided in medicinal amounts during pregnancy due to traditional concerns about uterine stimulation, and medicinal amounts are best avoided while breastfeeding.

For the other ingredients, talk with your doctor or pharmacist about whether this product is right for you during pregnancy or while breastfeeding.

Side effects, ingredient by ingredient Chicory Gum Arabic

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 5 matched ingredients can interact with medications — Chicory, Gum Arabic, Lactobacillus Acidophilus, Bifidobacterium Longum, Lactobacillus Gasseri.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 2,109 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, double-check antibiotic drugs with your pharmacist — space this probiotic several hours away from antibiotics so the antibiotics don't kill off the live organisms. Also check any diabetes medications (Moderate severity); chicory may lower blood sugar.

We have no documented interactions for several of the probiotic strains in this formula, so the checker below should catch any other medications you're on.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Fortify Optima Daily Probiotic is a multi-strain formula possibly effective for certain digestive and vaginal health issues if you're taking Lactobacillus acidophilus. If you take antibiotics or diabetes medications, you need to check with your pharmacist first — spacing matters for antibiotics, and your blood sugar monitoring may need adjusting.

Most people tolerate it well, but bloating and gas are common at the start. Ask your pharmacist or doctor before you begin, especially if you're pregnant, breastfeeding, or seriously ill.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 17 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Fortify Optima Daily Probiotic 100 Billion, straight from the product label.

Brand Nature's Way
Barcode (UPC) 033674157848
Net contents 30 Delayed-Release Capsules
Market status On market
Date entered into DSLD Oct 24, 2023
DSLD ID 293283
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Fortify Optima Daily Probiotic 100 Billion by Nature's Way, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
033674157848
IngredientAmount% DV
Lactobacillus casei LC-110 NP--
Lactobacillus paracasei LPC-370 NP--
Lactobacillus acidophilus LA-140 NP--
Lactobacillus brevis LBR-350 NP--
Lactobacillus rhamnosus GG0 NP--
Chicory Root Fiber0 NP--
Bifidobacterium animalis lactis BL-040 NP--
Gum Acacia Fiber0 NP--
Lactobacillus plantarum LP-1150 NP--
Bifidobacteria Blend0 NP--
Lactobacillus salivarius LS-330 NP--
HOWARU Lactobacillus rhamnosus HN0010 NP--
HOWARU Lactobacillus acidophilus NCFM0 NP--
Bifidobacterium0 NP--
Bifidobacterium animalis lactis Bi-070 NP--
HOWARU Bifidobacterium animalis lactis HN0190 NP--
Lactobacilli Blend0 NP--
Proprietary Plant-Based Prebiotic Blend75 mg--
Lactobacillus gasseri LG-360 NP--
Bifidobacterium longum infantis BI-260 NP--
Fortify Optima Daily 100 Billion CFU Proprietary Probiotic Blend575 mg--

Other ingredients: Cellulose, Hypromellose, Gellan Gum, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

POWERFUL PROBIOTICS FOR DAILY DIGESTIVE & IMMUNE HEALTH Specially formulated with a proprietary blend of probiotics, Fortify Optima is a higher potency probiotic with HN019, HN001, BL-04, and Bi-07, researched probiotic strains to support daily digestive and immune health. Lactobacilli cultures to support your small intestine Bifidobacteria cultures to support your colon FORMULATED WITH 15 PROBIOTIC STRAINS + PREBIOTICS Fortify Optima 100 Billion CFU formula contains 15 probiotic strains designed to support gut diversity + plant-based prebiotics. This unique prebiotic blend contains gum acacia and chicory root fiber as a food source for good bacteria.

DNA authenticated probiotic strains Researched probiotic strains

100 billion active cultures, guaranteed! Innovative bottle technology helps ensure this product will deliver 100 billion live probiotic cultures until the date of expiration to help balance your intestinal tract and support immune health.

Contains the doctor preferred probiotic for regularity Based on an IQVIA ProVoice survey of primary care physicians, HOWARU B. lactis HN019 is the doctor preferred probiotic strain for regularity as compared to other strains in leading probiotic brands, 52-week sales MULO, ending 10/3/2021; November 2021. Daily probiotic + prebiotics 100 billion live cultures per capsule 15 probiotic strains Plant-based prebiotic blend

The probiotic strains contained in this product are manufactured by IFF. Howaru Probiotic quality you can feel

Seals/Symbols

Certified Authentic Tru-ID

GFCO.org Gluten-Free Certification Organization Non GMO Project Verified nongmoproject.org

Formulation

No artificial colors Gluten-free

Potency of live cultures measured in Colony Forming Units (CFU).

Targeted delivery Each capsule is resistant to the harmful effects of stomach acid and distributes live cultures to the proper area of the small intestine and colon, right where they're needed most! One capsule, multiple benefits Taking fortify Optima advanced care every day helps support: A healthy gut microbiome Digestive health during occasional episodes of digestive irregularity A healthy immune response Guaranteed potency

Advanced care Digestive balance Immune health Guaranteed potency

Gluten free. No soy, dairy, or artificial colors. Non GMO Project Verified nongmoproject.org

FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

Copyright 2022 Nature's Way Brands, LLC

HOWARU is a registered trademark of IFF and is under license. HN019 and HN001 are trademarks of the Fonterra Group of companies used under license.

General Statements

Questions? 1-800-9NATURE / fortifyprobiotics.com

LGBN15784.D01 BLK9244D

FDA Statement of Identity

Probiotic Supplement

Suggested/Recommended/Usage/Directions

Recommendation: Adults take 1 capsule daily. May be taken at any time, with or without food.

Precautions

If you are pregnant, nursing, or taking any medications, consult a healthcare professional before use.

Keep out of reach of children.

Safety sealed with inner seal. Do not use if seal is broken or missing.

Storage

Keep tightly closed. Keep refrigerated to maintain maximum potency.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Fortify Optima Daily Probiotic 100 Billion by Nature's Way label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Fortify Optima Daily Probiotic 100 Billion label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Fortify Optima Daily Probiotic 100 Billion by Nature's Way

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Plant-Based Prebiotic Blend

75 mg per serving

Fortify Optima Daily 100 Billion CFU Proprietary Probiotic Blend

575 mg per serving
  • › Bifidobacteria Blend
  • › Lactobacilli Blend

Other (inactive) ingredients: Cellulose, Hypromellose, Gellan Gum, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Fortify Optima Daily Probiotic 100 Billion by Nature's Way Drug Interactions

Want to check YOUR meds against Fortify Optima Daily Probiotic 100 Billion?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,108Drugs
2,108 Moderate

Ingredients driving the most interactions

Gum Acacia Fiber 2,022
Chicory Root Fiber 86

Individual Drug Interactions

The ingredients in Fortify Optima Daily Probiotic 100 Billion interact with 2,108 drugs. Click any drug to see the details.

2 of the 4 ingredients in Fortify Optima Daily Probiotic 100 Billion interact with drugs. Each result below shows which ingredient is responsible. Gum Acacia Fiber Chicory Root Fiber

Each ingredient & the kinds of drugs it affects

For each ingredient in Fortify Optima Daily Probiotic 100 Billion with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Gum Acacia Fiber2 drug types · 2,022 drugs

Amoxicillin (Amoxil, Trimox)

Gum arabic can reduce the absorption of amoxicillin.
A small study in healthy volunteers shows that taking amoxicillin and gum arabic concurrently significantly reduces the absorption of amoxicillin. Separate doses of amoxicillin from gum arabic by at least 2 hours.

Likelihood Probable Evidence B
Oral Drugs

Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Gum arabic has been used as a suspending osmotic agent in drug formulations. It might improve bioavailability of water-insoluble drugs like naproxen, but reduce absorption of polar drugs like amoxicillin. To avoid changes in absorption, take gum arabic 30-60 minutes after oral medications.

Likelihood Possible Evidence B
Gum Acacia Fiber full monograph & interactions

Chicory Root Fiber1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, chicory might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research shows that chicory extracts have antidiabetic effects.

Likelihood Possible Evidence D
Chicory Root Fiber full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Fortify Optima Daily Probiotic 100 Billion, from the product label.

Nature's Way

See all Nature's Way products
Name
Nature's Way Brands, LLC
City
Green Bay
State
WI
ZipCode
54311
Phone Number
1-800-962-8873
Web Address
fortifyprobiotics.com
Pharmacist Counseling Corner

Fortify Optima Daily Probiotic 100 Billion by Nature's Way: Common Questions

Does Fortify Optima Daily Probiotic 100 Billion by Nature's Way interact with any medications?
Yes. Based on its ingredients, Fortify Optima Daily Probiotic 100 Billion has a known interaction with 2,108 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Fortify Optima Daily Probiotic 100 Billion contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this at the same time as my antibiotic?
No — antibiotics can kill the live bacteria in this probiotic, making it less effective. Separate them by a few hours if you can. Your pharmacist can help you figure out the best timing.
Will this help my IBS?
Lactobacillus acidophilus, which is in this product, is possibly effective for IBS. That means there's some evidence it may help, but it's not a guarantee. Talk with your doctor about what to expect.
Is it normal to feel bloated when I start this?
Yes, bloating, gas, and abdominal discomfort are the most common side effects when taking probiotics, though they're uncommon overall. They often settle down as your gut adjusts. If they don't ease up after a week or two, let your pharmacist know.
Can I take this if I'm on diabetes medication?
The Chicory Root Fiber in this product may lower blood sugar. Tell your doctor or pharmacist before you start, and they'll want to monitor your blood sugar more carefully.
Is this safe during pregnancy?
We don't have reliable safety data for most of the probiotics in this formula during pregnancy. Chicory should be avoided in medicinal amounts when you're pregnant. Talk with your obstetrician or pharmacist before starting.
What are the inactive ingredients?
The capsule contains cellulose, hypromellose, gellan gum, magnesium stearate, and silica — common binders and flow agents. None are active ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Fortify Optima Daily Probiotic 100 Billion is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Fortify Optima Daily Probiotic 100 Billion label
Go deeper

The Full Monographs Behind Fortify Optima Daily Probiotic 100 Billion’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Chicory

Interacts with 86 drugs

Chicory is best known as a caffeine-free coffee substitute and as a source of inulin, a soluble prebiotic fiber that may support digestion and regularity. Strong human evidence for most othe...

Read the full Chicory monograph → Herb & supplement monograph

Gum Arabic

Interacts with 2,022 drugs

Gum arabic is a soluble dietary fiber from the acacia tree that is widely used as a safe food additive and is sometimes taken as a supplement for digestive health and as a prebiotic. Early s...

Read the full Gum Arabic monograph →
Sources

Sources & How We Checked

Fortify Optima Daily Probiotic 100 Billion's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 69 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Chicory 13 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Stone-Dorshow T, Levitt MD. Gaseous response to ingestion of a poorly absorbed fructo-oligosaccharide sweetener. Am J Clin Nutr 1987;46:61-5. PubMed
  3. Briet F, et al. Symptomatic response to varying levels of fructo-oligosaccharides consumed occasionally or regularly. Eur J Clin Nutr 1995;49:501-7.
  4. Bouhnik Y, Vahedi K, Achour L, et al. Short-chain fructo-oligosaccharide administration dose-dependently increases fecal bifidobacteria in healthy humans. J Nutr 1999;129:113-6. PubMed
  5. Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-420S. PubMed
  6. Cadot, P., Kochuyt, A. M., van Ree, R., and Ceuppens, J. L. Oral allergy syndrome to chicory associated with birch pollen allergy. Int.Arch.Allergy Immunol. 2003;131(1):19-24. PubMed
  7. Friis, B., Hjorth, N., Vail, J. T., Jr., and Mitchell, J. C. Occupational contact dermatitis from Cichorium (chicory, endive) and Lactuca (lettuce). Contact Dermatitis 1975;1(5):311-313.
  8. Nemery, B. and Demedts, M. Occupational asthma in a chicory grower. Lancet 3-25-1989;1(8639):672-673. PubMed
  9. Pirson F, Detry B, Pilette C. Occupational rhinoconjunctivitis and asthma caused by chicory and oral allergy syndrome associated with bet v 1-related protein. J Investig Allergol Clin Immunol 2009;19(4):306-10.
  10. Willi R, Pfab F, Huss-Marp J, et al. Contact anaphylaxis and protein contact dermatitis in a cook handling chicory leaves. Contact Dermatitis 2009;60(4):226-7. PubMed
  11. Street RA, Sidana J, Prinsloo G. Cichorium intybus: traditional uses, phytochemistry, pharmacology, and toxicology. Evid Based Complement Alternat Med 2013;2013:579319.
  12. Bonnema AL, Kolberg LW, Thomas W, Slavin JL. Gastrointestinal tolerance of chicory inulin products. J Am Diet Assoc 2010;110(6):865-8. PubMed
  13. Devi Kt R, Sivalingam N. Cichorium intybus attenuates Streptozotocin-induced pancreatic ß-cell damage by inhibiting NF-?B activation and oxidative stress. J Appl Biomed 2020;18(2-3):70-9. PubMed

See these in context on the Chicory monograph →

Gum Arabic 8 references
  1. Jensen CD, Spiller GA, Gates JE, et al. The effect of acacia gum and a water-soluble dietary fiber mixture on blood lipids in humans. J Am Coll Nutr 1993;12:147-54. PubMed
  2. Eltayeb IB, Awad AI, Elderbi MA, Shadad SA. Effect of gum arabic on the absorption of a single oral dose of amoxicillin in healthy Sudanese volunteers. J Antimicrob Chemother 2004;54:577-8. PubMed
  3. Babiker R, Merghani TH, Elmusharaf K, et al. Effects of gum Arabic ingestion on body mass index and body fat percentage in healthy adult females: two-arm randomized, placebo controlled, double-blind trial. Nutr J 2012;11:111. PubMed
  4. Babiker R, Elmusharaf K, Keogh MB, Banaga AS, Saeed AM. Metabolic effect of gum Arabic (Acacia senegal) in patients with type 2 diabetes mellitus (T2DM): randomized, placebo controlled double blind trial. Functional Foods in Health and Disease. 2017;7(3): DOI
  5. Beneke CE, Viljoen AM, Hamman JH. Polymeric plant-derived excipients in drug delivery. Molecules. 2009;14(7):2602-20. PubMed
  6. Ali NE, Kaddam LA, Alkarib SY, et al. Gum Arabic (Acacia Senegal) Augmented Total Antioxidant Capacity and Reduced C-Reactive Protein among Haemodialysis Patients in Phase II Trial. Int J Nephrol. 2020;2020:7214673.
  7. Mortensen A, Aguilar F, Crebelli R, et al. Re-evaluation of acacia gum (E 414) as a food additive. EFSA J. 2017;15(4):e04741. PubMed
  8. Larson R, Nelson C, Korczak R, et al. Acacia Gum Is Well Tolerated While Increasing Satiety and Lowering Peak Blood Glucose Response in Healthy Human Subjects. Nutrients 2021;13(2):618. PubMed

See these in context on the Gum Arabic monograph →

Lactobacillus Gasseri 12 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Ramachandran L, Dontaraju VS, Patel K. Lactobacillus-associated spontaneous bacterial peritonitis in a liver cirrhosis patient on probiotics. Cureus. 2020;12(12):e11896. PubMed
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See these in context on the Lactobacillus Gasseri monograph →

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See these in context on the Bifidobacterium Longum monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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