Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

NDF Natural Detox Formula Ingredients & Drug Interactions

by Bioray

NDF Natural Detox Formula label
See full label image
Liquid Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking NDF Natural Detox Formula against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

NDF Natural Detox Formula is a dietary supplement by Bioray with 3 active ingredients. Its ingredients are commonly taken for digestive upset and gas, appetite stimulation, mild antimicrobial (topical).Based on those ingredients, 862 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Cilantro, micronized Yaeyama Chlorella. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against NDF Natural Detox Formula by Bioray

Ask about any prescription or over-the-counter medication and we check it for interactions with NDF Natural Detox Formula by Bioray — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of NDF Natural Detox Formula by Bioray

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 14 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (96 mg) without saying how much of each component you get.
  • “PolyFlor” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

This liquid formula contains 14 ingredients, with multiple probiotic strains as the active components: several Lactobacillus species (L. acidophilus, L. rhamnosus, L. reuteri, L. acidophilus DDS-1, L. bulgaricus, L. plantarum, L. casei, L. salivarius), Bifidobacterium species (B. longum, B. bifidum, B. infantis), and Streptococcus thermophilus. It also includes organic cilantro and micronized Yaeyama chlorella.

The remaining ingredients are inactive: deionized water and gluten-free alcohol, which serve as the liquid base.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: heavy metal detox and general detoxification.
  • We looked for evidence on: Diarrhea, Antibiotic-associated diarrhea, Constipation, Flatulence, Dyspepsia, Abdominal pain — and 4 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Coriander is rated "Insufficient Reliable Evidence To Rate" for Constipation, Diarrhea, Dyspepsia, Flatulence.
  • Also on file: Lactobacillus Acidophilus is rated "Insufficient Reliable Evidence To Rate" for Constipation, Rotaviral diarrhea.

The evidence for what this product actually does is mixed and mostly limited. L. acidophilus is possibly effective for irritable bowel syndrome, H. pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis.

B. bifidum is possibly effective for irritable bowel syndrome and respiratory tract infections. For most of the other probiotic strains, the evidence we hold rates them as insufficient to determine whether they work.

The cilantro and chlorella also lack strong evidence in our data for the conditions they're used for—the ratings are mostly insufficient to determine effectiveness, though chlorella is possibly effective for pregnancy-related iron deficiency.

The evidence, ingredient by ingredient Coriander Chlorella

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 7 of the 7 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 7 of 7.
  • General safety write-ups exist for 7 of 7.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The probiotic ingredients are generally well tolerated in healthy people, though mild gastrointestinal side effects like bloating, flatulence, abdominal discomfort, and diarrhea can occur, especially early on—these are uncommon. There's a rare but serious concern: live probiotic organisms can in uncommon cases cause infection (bacteremia or sepsis) in people with severely weakened immune systems, very critical illness, or indwelling catheters; these cases are thought to involve bacteria moving from where they naturally live in the body to the bloodstream.

Cilantro at food amounts is generally safe, though concentrated medicinal doses lack safety data. Anaphylaxis is rare but documented for both cilantro and chlorella in sensitive individuals.

Chlorella is generally well tolerated short-term but can cause allergic reactions, abdominal cramping, constipation, diarrhea, fatigue, nausea, and photosensitivity; product quality and purity vary widely. Pregnancy and lactation safety data are not on file for most ingredients; B. longum is rated possibly safe, but for others there isn't enough data to know either way—talk with your doctor before using this formula if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Coriander Chlorella

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 6 of the 7 matched ingredients can interact with medications — Coriander, Lactobacillus Acidophilus, Chlorella, Bifidobacterium Bifidum, Bifidobacterium Longum, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 862 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications if you take warfarin or other blood thinners (the chlorella may reduce their effectiveness). Space out any antibiotic doses several hours from this product.

If you're on blood pressure or diabetes medications, sedating drugs (like benzodiazepines or opioids), or photosensitizing drugs (like doxycycline or certain psoriasis medications), those interactions are documented and need a look-through before you start.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a multi-ingredient probiotic and detox formula. If you take warfarin, antibiotics, blood pressure or diabetes medications, sedating drugs, or drugs that make you sun-sensitive, you'll want to check your specific medications with our tool before starting.

If you have a weakened immune system or serious illness, talk with your doctor first. For healthy people with intact immune systems, it's generally well tolerated, though mild digestive side effects can happen early on.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 7 of 14 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about NDF Natural Detox Formula, straight from the product label.

Brand Bioray
Barcode (UPC) 705105323411
Net contents 4 fl. Oz.; 118 mL
Market status On market
Date entered into DSLD Oct 22, 2015
DSLD ID 53011
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for NDF Natural Detox Formula by Bioray, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Drop(s)
Maximum serving Sizes:
52 Drop(s)
Servings per container
74
UPC/BARCODE
705105323411
IngredientAmount% DV
L. acidophilus0 NP--
L. rhamnosus0 NP--
Proprietary Blend96 mg--
B. longum0 NP--
B. bifidum0 NP--
L. reuteri0 NP--
L. acidophilus DDS-10 NP--
L. bulgaricus0 NP--
L. plantarum0 NP--
L. casei0 NP--
B. infantis0 NP--
organic Cilantro0 NP--
L. salivarius0 NP--
micronized Yaeyama Chlorella0 NP--
PolyFlor0 NP--
L. thermophilus0 NP--

Other ingredients: deionized Water, gluten free Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Optimal Dose by Weight: Under 40 lbs: 13 drops, 2x per day. 41-75 lbs: 1 dropper (26 drops), 2x per day. Over 75 lbs: 2 droppers (52 drops), 2x per day.

Intake Instructions: Shake Well. Begin with 3-6 drops in water or juice twice (2x) a day. Increase intake by 3 drops per day, or as tolerated, to optimal dose. Drink water with fresh lemon juice and ensure bowels are moving daily. Sensitive individuals: Begin with 1 drop in water or juice twice (2x) a day. Increase intake by 1 drop every 3-4 days, or as tolerated, to optimal dose.

Precautions

If pregnant or nursing consult a health care professional.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to treat, diagnose, cure, or prevent any disease.

General Statements

Natural Detox Formula Heavy Metal Detox Tonic

Detox Replenish

FDA Statement of Identity

Daily Dietary Supplement

Formulation

Made with organic ingredients.

Seals/Symbols

generation rescue approved

Oriental Medicine Doctor formulated

Brand IP Statement(s)

NDF is a natural detoxifier that safely removes toxic heavy metals, chemicals, and pesticides while balancing essential minerals.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

NDF Natural Detox Formula by Bioray label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

NDF Natural Detox Formula label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in NDF Natural Detox Formula by Bioray

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Drop(s) Dosage formLiquid Servings per container74 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

96 mg per serving

Other (inactive) ingredients: Deionized Water, Gluten free Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

NDF Natural Detox Formula by Bioray Drug Interactions

Want to check YOUR meds against NDF Natural Detox Formula?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
862Drugs
862 Moderate

Ingredients driving the most interactions

organic Cilantro 717
micronized Yaeyama Chlorella 337

Individual Drug Interactions

The ingredients in NDF Natural Detox Formula interact with 862 drugs. Click any drug to see the details.

2 of the 3 ingredients in NDF Natural Detox Formula interact with drugs. Each result below shows which ingredient is responsible. organic Cilantro micronized Yaeyama Chlorella

Each ingredient & the kinds of drugs it affects

For each ingredient in NDF Natural Detox Formula with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Cilantro4 drug types · 717 drugs

Antidiabetes Drugs

Theoretically, coriander might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Evidence from animal research suggests that coriander fruit and coriander extract can reduce blood glucose levels. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, coriander might increase the risk of hypotension when taken with antihypertensive drugs.
Evidence from animal research suggests that coriander fruit can lower blood pressure.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, coriander might cause additive sedative effects when taken with CNS depressants.
Evidence from animal research suggests that coriander fruit extract has sedative effects.

Likelihood Possible Evidence D
Photosensitizing Drugs

Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Evidence from in vitro research suggests that coriandrin, a constituent of coriander, has photosensitizing effects.

Likelihood Possible Evidence D
organic Cilantro full monograph & interactions

micronized Yaeyama Chlorella2 drug types · 337 drugs

Photosensitizing Drugs

Theoretically, chlorella might have additive effects with photosensitizing drugs.
Chlorella has been reported to cause photosensitization. In five case reports, patients who had ingested chlorella exhibited swelling followed by erythematopurpuric lesions on sun-exposed areas of the body. Theoretically, concomitant use with photosensitizing drugs may exacerbate effects.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, chlorella might reduce the clinical effects of warfarin.
Chlorella contains significant amounts of vitamin K. There is at least one case report of warfarin therapy becoming sub-therapeutic after initiation of chlorella supplements.

Likelihood Possible Evidence D
micronized Yaeyama Chlorella full monograph & interactions
The maker

Brand information

Manufacturer and brand details for NDF Natural Detox Formula, from the product label.

Bioray

See all Bioray products
Name
Bioray Inc.
City
Laguna Hills
State
CA
Phone Number
(888) 635-9582
Web Address
bioray.com
Pharmacist Counseling Corner

NDF Natural Detox Formula by Bioray: Common Questions

Does NDF Natural Detox Formula by Bioray interact with any medications?
Yes. Based on its ingredients, NDF Natural Detox Formula has a known interaction with 862 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
NDF Natural Detox Formula contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is it safe to take this if I'm on antibiotics?
The probiotic strains here interact with antibiotics: the antibiotics may kill the live organisms in the formula and reduce its effectiveness. The safety notes also recommend spacing them out. Talk with your pharmacist about timing—typically you'd take them a few hours apart, and you might want to wait until you've finished your antibiotic course before restarting.
Can I take this while pregnant?
Safety data aren't well established for most of the ingredients in this formula during pregnancy. One ingredient, B. longum, is rated possibly safe. For the others, there just isn't enough information to know either way. You should talk with your doctor or pharmacist before using this formula if you're pregnant or planning to become pregnant.
What are the probiotics in this formula supposed to do?
Probiotics are live beneficial bacteria. L. acidophilus and B. bifidum in here are possibly effective for irritable bowel syndrome, and L. acidophilus may help with antibiotic-associated diarrhea, H. pylori, and bacterial vaginosis. For several of the other strains, we don't have strong evidence yet on whether they work.
Are there any common side effects I should expect?
Most people tolerate this formula well, but some experience mild digestive side effects early on—bloating, flatulence, stomach discomfort, or loose stools. These are uncommon and often pass. If you have severe or persistent symptoms, stop and talk with your pharmacist.
I take warfarin. Can I use this product?
The chlorella in this formula contains vitamin K, which can interfere with how warfarin works and make it less effective. This is a significant interaction. Do not start this product without talking to your doctor or pharmacist first; you may need closer monitoring of your blood clotting if you do use it.
What is the cilantro in here for?
Cilantro is sometimes used in herbal detox formulas, but we don't have strong evidence that it actually works for any specific condition. The good news is that cilantro at food amounts is generally safe, though medicinal doses lack solid safety data.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if NDF Natural Detox Formula is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

NDF Natural Detox Formula label
Go deeper

The Full Monographs Behind NDF Natural Detox Formula’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Coriander

Interacts with 717 drugs

Coriander (also called cilantro) is a common cooking herb and spice that has long been used in traditional medicine for digestive complaints. As a food it is generally safe for most people,...

Read the full Coriander monograph → Herb & supplement monograph

Chlorella

Interacts with 337 drugs

Chlorella is a nutrient-rich freshwater green algae taken as a supplement for general wellness, immune support, and 'detox.' Some small studies suggest possible benefits for cholesterol, blo...

Read the full Chlorella monograph →
Sources

Sources & How We Checked

NDF Natural Detox Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 98 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Bifidobacterium Longum 21 references
  1. Ha GY, Yang CH, Kim H, Chong Y. Case of sepsis caused by Bifidobacterium longum. J Clin Microbiol 1999;37:1227-8.
  2. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  3. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  4. Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130(6):1355-60. PubMed
  5. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  6. Pellonperä O, Vahlberg T, Mokkala K, et al. Weight gain and body composition during pregnancy: a randomised pilot trial with probiotics and/or fish oil. Br J Nutr. 2020 Nov 4:1-11. PubMed
  7. Pellonperä O, Mokkala K, Houttu N, et al. Efficacy of fish oil and/or probiotic intervention on the incidence of gestational diabetes mellitus in an at-risk group of overweight and obese women: A randomized, placebo-controlled, double-blind clinical trial PubMed
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
  10. Enomoto T, Sowa M, Nishimori K, et al. Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergol Int 2014;63(4):575-85. PubMed
  11. US Food and Drug Administration (FDA). Dear Healthcare Provider Letter: Warning Regarding Use of Probiotics in Preterm Infants. September 2023. Available at: https://www.fda.gov/media/172606/download?attachment. Accessed November 1, 2023.
  12. Pillai A, Tan J, Paquette V, Panczuk J. Does probiotic bacteremia in premature infants impact clinically relevant outcomes? A case report and updated review of literature. Clin Nutr ESPEN. 2020;39:255-259. PubMed
  13. Sabaté JM, Iglicki F. Effect of Bifidobacterium longum 35624 on disease severity and quality of life in patients with irritable bowel syndrome. World J Gastroenterol 2022;28(7):732-744.
  14. Malaguarnera M, Greco F, Barone G, Gargante MP, Malaguarnera M, Toscano MA. Bifidobacterium longum with fructo-oligosaccharide (FOS) treatment in minimal hepatic encephalopathy: a randomized, double-blind, placebo-controlled study. Dig Dis Sci 2007;52(11) PubMed
  15. Zbinden A, Zbinden R, Berger C, Arlettaz R. Case series of Bifidobacterium longum bacteremia in three preterm infants on probiotic therapy. Neonatology 2015;107(1):56-9.
  16. Tamaki H, Nakase H, Inoue S, et al. Efficacy of probiotic treatment with Bifidobacterium longum 536 for induction of remission in active ulcerative colitis: A randomized, double-blinded, placebo-controlled multicenter trial. Dig Endosc 2016;28(1):67-74.
  17. Bertelli C, Pillonel T, Torregrossa A, et al. Bifidobacterium longum bacteremia in preterm infants receiving probiotics. Clin Infect Dis 2015;60(6):924-7. PubMed
  18. Esaiassen E, Cavanagh P, Hjerde E, Simonsen GS, Støen R, Klingenberg C. Bifidobacterium longum subspecies infantis bacteremia in 3 extremely preterm infants receiving probiotics. Emerg Infect Dis 2016;22(9):1664-6.
  19. Tena D, Losa C, Medina MJ, Sáez-Nieto JA. Peritonitis caused by Bifidobacterium longum: case report and literature review. Anaerobe 2014;27:27-30. PubMed
  20. Sangkanjanavanich S, Pradubpongsa P, Mitthamsiri W, Sangasapaviliya A, Boonpiyathad T. Bifidobacterium infantis 35624 efficacy in patients with uncontrolled asthma: A randomized placebo-controlled trial. Ann Allergy Asthma Immunol 2022;129(6):790-792. PubMed
  21. Wilson HL, Ong CW. Bifidobacterium longum vertebrodiscitis in a patient with cirrhosis and prostate cancer. Anaerobe 2017;47:47-50. PubMed

See these in context on the Bifidobacterium Longum monograph →

Bifidobacterium Bifidum 7 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  3. Rerksuppaphol S, Rerksuppaphol L. Randomized controlled trial of probiotics to reduce common cold in schoolchildren. Pediatr Int. 2012;54(5):682-7. PubMed
  4. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  5. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  6. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  7. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed

See these in context on the Bifidobacterium Bifidum monograph →

Lactobacillus Delbrueckii 9 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
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Coriander 12 references
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Chlorella 13 references
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Streptococcus Thermophilus 21 references
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See these in context on the Streptococcus Thermophilus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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