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Dietary supplement

Full Spectrum Cinnamon 375 mg Ingredients & Drug Interactions

by Swanson

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Full Spectrum Cinnamon 375 mg is a dietary supplement by Swanson with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, digestive upset, antioxidant support.Based on those ingredients, 442 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cinnamon. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Full Spectrum Cinnamon 375 mg by Swanson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: cinnamon (cassia variety), at 375 mg per capsule. Cassia cinnamon is the dried bark of the cinnamon tree, commonly used as a spice and in herbal supplements.

The capsule also holds inactive ingredients — gelatin, rice flour, and silica — which help form and stabilize the supplement.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Cassia Cinnamon's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports cardiovascular health and blood sugar metabolism.
  • We looked for evidence on: Diabetes, Dyslipidemia, Hypertension, Impaired glucose tolerance (prediabetes), Stroke, Metabolic syndrome — and 1 related terms.
  • The closest evidence on file: Cassia Cinnamon is rated "Insufficient Reliable Evidence To Rate" for Diabetes (Natural Medicines).
  • Also on file: Cassia Cinnamon is rated "Insufficient Reliable Evidence To Rate" for Dyslipidemia, Hypertension, Stroke, Impaired glucose tolerance (prediabetes).

The evidence isn't established for cinnamon in any of the conditions we hold data on — amenorrhea, angina, common cold, diabetes, diarrhea, and high cholesterol all carry a rating of insufficient reliable evidence. That doesn't mean cinnamon doesn't work for these purposes; it means the studies we have don't yet prove it does.

If you're considering it for a specific health goal, talk with your pharmacist about what the current research actually shows.

The evidence, ingredient by ingredient Cassia Cinnamon

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cinnamon in food amounts is generally well tolerated, and this supplement is likely safe at its 375 mg dose. However, the facts do note a concern: cassia cinnamon's coumarin content can harm the liver if you take very large doses for a long time.

In clinical trials at doses up to 12 grams daily for 3 months, liver enzyme levels didn't rise significantly, but animal studies and rare human case reports of extremely high coumarin intake (50–7,000 mg daily) have shown liver damage that reversed once the coumarin stopped. In a small trial, one person on 1 gram daily developed a rash, and there are isolated reports of contact dermatitis in people allergic to cinnamic alcohol.

One person also experienced low blood sugar seizure, though it's unclear if cinnamon caused it.

Side effects, ingredient by ingredient Cassia Cinnamon

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cassia Cinnamon.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 443 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, check any drugs that are hard on the liver and any diabetes medications (blood-sugar-lowering drugs). Both categories carry a moderate risk of added effects with cinnamon.

Use the medication search tool on this page to run your exact prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Cinnamon at this dose is generally well tolerated and has a long history as a food spice. If you're on diabetes medications or drugs that stress your liver, check your medications with our tool first and talk with your pharmacist — you may need dose adjustments.

For pregnancy and breastfeeding, food amounts are fine, but avoid concentrated supplement doses due to limited safety data.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Full Spectrum Cinnamon 375 mg, straight from the product label.

Brand Swanson
Barcode (UPC) 087614110257
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Aug 22, 2025
DSLD ID 337848
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Full Spectrum Cinnamon 375 mg by Swanson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
90
UPC/BARCODE
087614110257
IngredientAmount% DV
Cinnamon750 mg--

Other ingredients: Gelatin, Rice Flour, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Supports cardiovascular health and blood sugar metabolism Provides metabolic support Manges blood sugar levels

Blood sugar support

General Statements

Science-backed quality since 1969

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take two capsules three times per day with food and water.

Precautions

Warning: For adults only. Keep out of reach of children.

Do not take this product if you are pregnant or nursing. Consult your healthcare provider before using this or any product if you are taking medication or have a medical condition.

Warning: Cancer and Reproductive Harm- www.P65Warnings.ca.gov Do not use if seal is broken.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

Cinnamon 375 mg per capsule

FDA Statement of Identity

Herbal Supplement

See for yourself

Full Spectrum Cinnamon 375 mg by Swanson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Full Spectrum Cinnamon 375 mg by Swanson

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Cinnamon

Interacts with
442 drugs
750 mg per serving

Cassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evi...

Cinnamon monograph & interactions

Other (inactive) ingredients: Gelatin, Rice Flour, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Full Spectrum Cinnamon 375 mg by Swanson Drug Interactions

Want to check YOUR meds against Full Spectrum Cinnamon 375 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
442Drugs
442 Moderate

Ingredients driving the most interactions

Cinnamon 442

Each ingredient & the kinds of drugs it affects

For each ingredient in Full Spectrum Cinnamon 375 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Cinnamon2 drug types · 442 drugs

Antidiabetes Drugs

Theoretically, cassia cinnamon may have additive effects with antidiabetes drugs.
Cassia cinnamon may lower blood glucose levels, and have additive effects in patients treated with antidiabetic agents. Dose adjustments to diabetes medications might be necessary.

Likelihood Possible Evidence B
Hepatotoxic Drugs

Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
There is some concern that ingesting large amounts of cassia cinnamon for an extended duration might cause hepatotoxicity in some people. Cassia cinnamon contains coumarin, which can cause hepatotoxicity in animal models. In humans, very high doses of coumarin from 50-7000 mg/day can result in hepatotoxicity that resolves when coumarin use is discontinued. Lower amounts might also cause liver problems in sensitive people, such as those with liver disease or those taking potentially hepatotoxic agents.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Full Spectrum Cinnamon 375 mg, from the product label.

Swanson

See all Swanson products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
swanson.com
Pharmacist Counseling Corner

Full Spectrum Cinnamon 375 mg by Swanson: Common Questions

Does Full Spectrum Cinnamon 375 mg by Swanson interact with any medications?
Yes. Based on its ingredients, Full Spectrum Cinnamon 375 mg has a known interaction with 442 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Full Spectrum Cinnamon 375 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take if I'm pregnant or breastfeeding?
Cinnamon in food amounts is likely safe during pregnancy and breastfeeding. However, the safety data for concentrated supplement doses like this one is limited. Talk with your doctor or pharmacist for personalized advice before taking it during pregnancy or while nursing.
Can cinnamon actually help with blood sugar or cholesterol?
The evidence we have doesn't establish that cinnamon works for diabetes, high cholesterol, or the other conditions listed on this supplement. That means the studies don't yet prove it does — but it's not proven it doesn't either. If you're interested in cinnamon for a specific health goal, ask your pharmacist what current research shows.
What are the side effects?
In clinical trials, a small number of people reported a rash. There are also isolated case reports of skin reactions in people with a documented allergy to cinnamic alcohol. One person experienced a low blood sugar seizure, though it's unclear if cinnamon caused it. At this dose, serious side effects are uncommon.
Is there any concern about liver damage from cinnamon?
Cassia cinnamon contains coumarin, a compound that can harm the liver at very high doses over extended time. At this product's 375 mg dose, clinical trials up to 12 grams daily for 3 months did not show concerning changes to liver enzymes. However, the safety data advises against high-dose, long-term use if you're concerned about liver health — especially if you already take medications that stress the liver.
What does 'full spectrum' mean on this product?
The facts we hold don't explain what 'full spectrum' means for this particular cinnamon supplement. That's a marketing term — ask the manufacturer or your pharmacist if you'd like details about how this formulation differs from other cinnamon products.
How much of this should I take?
The facts show this is a 375 mg capsule of cinnamon, but they don't specify a recommended dose or duration. Check the label on the bottle or talk with your pharmacist to find the dosage that's right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Full Spectrum Cinnamon 375 mg label
Go deeper

The Full Monographs Behind Full Spectrum Cinnamon 375 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Full Spectrum Cinnamon 375 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 20 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cassia Cinnamon 20 references
  1. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  2. Khan A, Safdar M, Ali Khan M, et al. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 2003;26:3215-8. PubMed
  3. De Benito V, Alzaga R. Occupational allergic contact dermatitis from cassia (Chinese cinnamon) as a flavouring agent in coffee. Contact Dermatitis 1999;40:165. PubMed
  4. Drake TE, Maibach HI. Allergic contact dermatitis and stomatitis caused by a cinnamic aldehyde-flavored toothpaste. Arch Dermatol 1976;112:202-3.
  5. Press release. Cinnamon capsules to reduce blood sugar are medicinal products! Efficacy has not been scientifically proven - some products contain high levels of coumarin. Federal Institute of Risk Assessment (BfM), Germany, November 11, 2006. Available a
  6. Felter SP, Vassallo JD, Carlton BD, Daston GP. A safety assessment of coumarin taking into account species-specificity of toxicokinetics. Food Chem Toxicol 2006;44:462-75. PubMed
  7. Crawford P. Effectiveness of cinnamon for lowering hemoglobin A1C in patients with type 2 diabetes: a randomized, controlled trial. J Am Board Fam Med 2009;22:507-12. PubMed
  8. Akilen, R., Tsiami, A., Devendra, D., and Robinson, N. Glycated haemoglobin and blood pressure-lowering effect of cinnamon in multi-ethnic Type 2 diabetic patients in the UK: a randomized, placebo-controlled, double-blind clinical trial. Diabet.Med. 2010; PubMed
  9. Lu T, Sheng H Wu J Cheng Y Zhu J Chen Y. Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes. Nutr Res. 2012;32(6):408-412. PubMed
  10. Choi, J., Lee, K. T., Ka, H., Jung, W. T., Jung, H. J., and Park, H. J. Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties. Arch Pharm Res 2001;24(5):418-423.
  11. Altschuler JA, Casella SJ, MacKenzie TA, Curtis KM. The effect of cinnamon on A1C among adolescents with type 1 diabetes. Diabetes Care 2007;30(4):813-6. PubMed
  12. Stoecker BR, Zhan Z, Luo R, et al. Cinnamon extract lowers blood glucose in hyperglycemic subjects. FASEB J. 2010;22:722.1 (Abstract only). DOI
  13. Admani S, Hill H, Jacob SE. Cinnamon Sugar Scrub Dermatitis: "Natural" Is Not Always Best. Pediatr Dermatol. 2017;34(1):e42-e43. PubMed
  14. Isaac-Renton M, Li MK, Parsons LM. Cinnamon spice and everything not nice: many features of intraoral allergy to cinnamic aldehyde. Dermatitis. 2015;26(3):116-21. PubMed
  15. Vandersall A, Katta R. Eyelid dermatitis as a manifestation of systemic contact dermatitis to cinnamon. Dermatitis. 2015 Jul-Aug;26(4):189. PubMed
  16. Wickenberg J, Lindstedt S, Nilsson J, Hlebowicz J. Cassia cinnamon does not change the insulin sensitivity or the liver enzymes in subjects with impaired glucose tolerance. Nutr J 2014 Sep 24;13:96. PubMed
  17. Brancheau D, Patel B, Zughaib M. Do cinnamon supplements cause acute hepatitis? Am J Case Rep 2015;16:250-4. PubMed
  18. Shekarchizadeh-Esfahani P, Heydarpour F, Izadi F, Jalili C. The effect of cinnamon supplementation on liver enzymes in adults: A systematic review and meta-analysis of randomized controlled trials. Complement Ther Med 2021;58:102699. PubMed
  19. Bernaola J, Valverde-Monge M, Otal-Buesa M, Cullen D, Heras-Mendaza F. Cinnamon allergic contact cheilitis. Contact Dermatitis 2023;88(5):418-419. PubMed
  20. Patel K, Howard M, Tate B. Cheilitis caused by allergic contact dermatitis to cinnamon in chai tea: A case report. Contact Dermatitis 2023;88(3):239-240. PubMed

See these in context on the Cassia Cinnamon monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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