No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Fundamental Sulfur II Ingredients & Drug Interactions

by Douglas Laboratories

Tablet Or Pill Category: Other Combinations
No known interaction
The interaction bottom line No known interaction

Fundamental Sulfur II is a dietary supplement by Douglas Laboratories with 2 active ingredients. Its ingredients are commonly taken for correcting molybdenum deficiency, supporting enzyme function, general nutritional supplementation.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Fundamental Sulfur II by Douglas Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Fundamental Sulfur II contains two active ingredients: molybdenum and methylsulfonylmethane. Molybdenum is a mineral that plays a role in various enzyme functions in your body.

The product also contains several inactive ingredients—cellulose, stearic acid, magnesium stearate, silica, and pharmaceutical glaze—which are binders and fillers that hold the tablet together.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Molybdenum's overall clinical evidence instead.

Strong

Strong clinical evidence supports Molybdenum for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Molybdenum deficiency — rated "Likely Effective" (Natural Medicines).

Molybdenum is likely effective for molybdenum deficiency, though deficiency is rare in people eating a normal diet. For acne, iron deficiency anemia, asthma, osteoporosis, and esophageal cancer, there isn't enough reliable evidence to say whether molybdenum works.

We don't have effectiveness data on file for methylsulfonylmethane.

The evidence, ingredient by ingredient Molybdenum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Molybdenum is generally well tolerated when taken in amounts that don't exceed 2 mg per day. High-dose supplements are rarely necessary and may cause problems.

One case report linked very high supplemental doses (300–800 micrograms daily over 18 days) to serious neurological effects including psychosis, seizures, and brain damage—though this is an extreme outlier. If you have a stainless steel angioplasty stent, talk with your cardiologist before taking molybdenum supplements, as contact allergy to the mineral may increase the risk of stent restenosis.

For pregnancy, molybdenum from food and prenatal vitamins is generally fine, but avoid high-dose supplements unless your doctor advises it. The safety data for methylsulfonylmethane in pregnancy and breastfeeding is not on file.

Side effects, ingredient by ingredient Molybdenum

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. We could not check methylsulfonylmethane for drug interactions.

If you take any medications, use the search tool on this page to verify your specific drugs.

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

Fundamental Sulfur II may be worth considering if you have molybdenum deficiency, though this is uncommon. If you have a stainless steel heart stent or are pregnant or breastfeeding, talk with your own doctor or pharmacist before starting—they can give you personalized advice based on your health history.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Fundamental Sulfur II, straight from the product label.

Brand Douglas Laboratories
Barcode (UPC) 745287030363
Net contents 100 Tablet(s)
Market status On market
Date entered into DSLD Jul 25, 2012
DSLD ID 10945
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Fundamental Sulfur II by Douglas Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
100
UPC/BARCODE
745287030363
IngredientAmount% DV
Molybdenum25 mcg33%
Methylsulfonylmethane500 mg--

Other ingredients: Cellulose, Stearic Acid, Magnesium Stearate, Silica, Pharmaceutical Glaze

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General

MSM2

FDA Statement of Identity

A Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Usage: As a dietary supplement, adults take 1 tablet three times daily or as directed by physician.

Precautions

KEEP OUT OF REACH OF CHILDREN.

Tamper resistant package, do not use if outer seal is missing.

Storage

For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)

See for yourself

Fundamental Sulfur II by Douglas Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Fundamental Sulfur II by Douglas Laboratories

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container100 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Molybdenum

No known
interactions
25 mcg per serving Form: Molybdenum Amino Acid Chelate

Molybdenum is an essential trace mineral your body needs in tiny amounts to help certain enzymes work. Most people get enough from a normal diet, so s...

Molybdenum monograph & interactions

Methylsulfonylmethane

500 mg per serving

Other (inactive) ingredients: Cellulose, Stearic Acid, Magnesium Stearate, Silica, Pharmaceutical Glaze. These complete the product’s ingredient list but are not active constituents.

Interaction report

Fundamental Sulfur II by Douglas Laboratories Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Fundamental Sulfur II. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Fundamental Sulfur II, from the product label.

Douglas Laboratories

See all Douglas Laboratories products
Name
Douglas Laboratories
Street Address
600 Boyce Road
City
Pittsburgh
State
PA
ZipCode
15205
Phone Number
1.800.245.4440
Web Address
www.douglaslabs.com
Pharmacist Counseling Corner

Fundamental Sulfur II by Douglas Laboratories: Common Questions

Does Fundamental Sulfur II by Douglas Laboratories interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Fundamental Sulfur II. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Fundamental Sulfur II contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is molybdenum safe to take every day?
Molybdenum is generally well tolerated at doses that don't exceed 2 mg per day. High-dose supplements are rarely necessary and can cause problems, so stick to the amounts in your supplement and don't exceed the daily limit without medical advice.
Can I take this if I'm pregnant?
Molybdenum from food and prenatal vitamins is generally fine, but avoid high-dose supplements unless your doctor tells you to. The safety data for methylsulfonylmethane in pregnancy isn't on file, so talk with your doctor or pharmacist to see if this product is right for you.
What is molybdenum used for in the body?
Molybdenum is a mineral that works with enzymes to support normal body functions. It's present in many everyday foods, and deficiency is rare with a normal diet.
Will this help my acne?
There isn't enough reliable evidence to say whether molybdenum helps acne. This product is likely effective only for molybdenum deficiency.
I have a heart stent—is it safe to take this?
If you have a stainless steel angioplasty stent, check with your cardiologist before starting molybdenum supplements. Some people have developed an allergy to molybdenum from stents, and this may increase the risk of problems with the stent.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Fundamental Sulfur II is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Fundamental Sulfur II label
Go deeper

The Full Monographs Behind Fundamental Sulfur II’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Fundamental Sulfur II's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Molybdenum 8 references
  1. Chan S, Gerson B, Subramaniam S. The role of copper, molybdenum, selenium, and zinc in nutrition and health. Clin Lab Med 1998;18:673-85. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Rajagopalan KV. Molybdenum: an essential trace element in human nutrition. Annu Rev Nutr 1988;8:401-27. PubMed
  4. Selden AI, Berg NP, Soderbergh A, Bergstrom BE. Occupational molybdenum exposure and a gouty electrician. Occup Med (Lond) 2005;55:145-8. PubMed
  5. Al-Saleh E, Nandakumaran M, Al-Shammari M, Al-Harouny A. Maternal-fetal status of copper, iron, molybdenum, selenium and zinc in patients with gestational diabetes. J Matern Fetal Neonatal Med 2004;16:15-21. PubMed
  6. Koster R, Vieluf D, Kiehn M, et al. Nickel and molybdenum contact allergies in patients with coronary in-stent restenosis. Lancet 2000;356:1895-7. PubMed
  7. Vyskocil A, Viau C. Assessment of molybdenum toxicity in humans. J Appl Toxicol 1999;19:185-92. DOI
  8. Momcilovic, B. A case report of acute human molybdenum toxicity from a dietary molybdenum supplement--a new member of the "Lucor metallicum" family. Arh.Hig.Rada Toksikol. 1999;50(3):289-297. DOI

See these in context on the Molybdenum monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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