No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Gamma-O Ingredients & Drug Interactions

by Gamma Labs

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Gamma-O is a dietary supplement by Gamma Labs with 2 active ingredients. Its ingredients are commonly taken for high cholesterol, menopausal symptoms, athletic performance and muscle building.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Gamma-O by Gamma Labs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Gamma-O contains two active ingredients: gamma oryzanol and conjugated linoleic acid. Gamma oryzanol is a compound from rice bran oil that may help with cholesterol levels.

Conjugated linoleic acid is a fatty acid sometimes used in health supplements. The product also contains several inactive ingredients — gelatin, D-limonene, polysorbate 80, mixed tocopherols, titanium dioxide, and food colorings (yellow 5 and 6, blue 1, red 40) — which serve as the capsule shell and stabilizers.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Gamma-oryzanol's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: builds muscle and increases testosterone levels.
  • We looked for evidence on: Athletic performance, Muscle strength, testosterone enhancement, endocrine function.
  • The closest evidence on file: Gamma-oryzanol is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: Gamma-oryzanol is rated "Insufficient Reliable Evidence To Rate" for Muscle strength.

Gamma oryzanol is possibly effective for dyslipidemia (high cholesterol and related blood lipid problems) based on the evidence we have. For athletic performance and atopic dermatitis (eczema), there isn't enough reliable evidence to say whether it works.

We don't have effectiveness data on file for conjugated linoleic acid in this product.

The evidence, ingredient by ingredient Gamma-oryzanol

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Gamma oryzanol is generally well tolerated in studies, though long-term safety hasn't been thoroughly studied. The safety data advises against using it during pregnancy — there isn't enough information to know it's safe.

The same goes for breastfeeding: there's no reliable safety data, so it's best avoided. We don't have pregnancy or breastfeeding safety information on file for conjugated linoleic acid.

Side effects, ingredient by ingredient Gamma-oryzanol

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That said, we don't hold interaction data for conjugated linoleic acid, so if you take any medications, ask your pharmacist to confirm it won't affect them.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and some safety-information gaps remain.

Gamma-O may be worth considering if you're looking to support cholesterol levels, since gamma oryzanol shows promise for dyslipidemia. If you're pregnant, breastfeeding, or take any medications, talk with your doctor or pharmacist before starting it — they can weigh whether it's right for your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 26, 2011.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Gamma-O, straight from the product label.

Brand Gamma Labs
Barcode (UPC) 689076880053
Net contents 150 Microlozenge(s)
Market status On market
Date entered into DSLD Oct 26, 2011
DSLD ID 774
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Gamma-O by Gamma Labs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Liquid Cap(s)
Maximum serving Sizes:
2 Liquid Cap(s)
UPC/BARCODE
689076880053
IngredientAmount% DV
Calories11 {Calories}--
Calories from Fat11 {Calories}--
Total Fat1 g2%
Gamma Oryzanol1000 mg--
Conjugated Linoleic Acid1000 mg--

Other ingredients: Gelatin, D-Limonene, Polysorbate 80, Mixed Tocopherols, Titanium Dioxide, FD&C Yellow 6, FD&C Yellow 5, FD&C Blue 1, FD&C Red 40

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

A Dietary Supplement

Formula

FOR PROFESSIONAL ATHLETES

Formulation

NO BANNED SUBSTANCES 100% APPROVED

General Statements

25%MORE-FREE! 25%MORE-FREE! 25%MORE-FREE!

BUILDS MUSCLE WITH GAMMA ORYZANOL

BURNS FAT WITH CLA

Gamma-O has been demonstrated to naturally increase testosterone levels and enhance the release of endorphins that lower stress. Used as part of a sound training program, the increase in testosterone and endorphins aids in the development of lean muscle tissue while burning off excess fat without the harmful side effects of steroids or andro products. Additionally, Gamma-O acts to interfere with the absorption of cholesterol into the body, helping to naturally maintain cholesterol levels already within the normal range. Gamma-O also possesses strong antioxidant properties which can protect heart vessels from free-radical damage. Gamma Oryzanol is a rice bran extract, made from plant sterols and ferulic acid. Our proprietary process of turning the powder extract into a liquid emulsion enhances absorption. This is the most powerful form of Gamma Oryzanol that can be absorbed by the human body. Professional atheletes on Gamma-O experienced increased strength, reduced excess body fat, enhanced energy during workouts and reduced post-workout soreness.

Licaps(R) Visible · Liquid · Capsule(TM)

TESTOSTERONE BOOSTER

Suggested/Recommended/Usage/Directions

Directions: Take 2 liquid caps twice daily with food. A daily dosage of 4 capsules per day ensures a 1 moth supply in every bottle.

See for yourself

Gamma-O by Gamma Labs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Gamma-O by Gamma Labs

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Liquid Cap(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Gamma Oryzanol

No known
interactions
1000 mg per serving

Gamma-oryzanol is a mix of plant compounds taken from rice bran oil, used mainly for cholesterol, menopause symptoms, and as a sports supplement. The...

Gamma Oryzanol monograph & interactions

Conjugated Linoleic Acid

1000 mg per serving

Other (inactive) ingredients: Gelatin, D-Limonene, Polysorbate 80, Mixed Tocopherols, Titanium Dioxide, FD&C Yellow 6, FD&C Yellow 5, FD&C Blue 1, FD&C Red 40. These complete the product’s ingredient list but are not active constituents.

Interaction report

Gamma-O by Gamma Labs Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Gamma-O. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Gamma-O, from the product label.

Pharmacist Counseling Corner

Gamma-O by Gamma Labs: Common Questions

Does Gamma-O by Gamma Labs interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Gamma-O. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Gamma-O contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Gamma-O if I'm pregnant?
The safety data advises against it during pregnancy — there isn't enough information to know it's safe. Talk with your doctor before taking it if you're pregnant or planning to become pregnant.
Can I breastfeed while taking Gamma-O?
There's no reliable safety data for breastfeeding, so it's best avoided. Check with your doctor or pharmacist for personalized advice.
Does gamma oryzanol really help with cholesterol?
It's possibly effective for dyslipidemia (high cholesterol and related blood lipid problems) based on the evidence we have, though more research may be helpful.
What are the inactive ingredients in this capsule?
The capsule contains gelatin, D-limonene, polysorbate 80, mixed tocopherols, titanium dioxide, and food colorings (FD&C yellow 5 and 6, blue 1, and red 40).
Are there any reported side effects from gamma oryzanol?
In studies, gamma oryzanol is generally well tolerated — no specific adverse effects are documented in our data. Long-term safety hasn't been established, so watch how you feel.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Gamma-O is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Gamma-O label
Sources

Sources & How We Checked

Gamma-O's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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