Gas Stop Enzyme Formula Ingredients & Drug Interactions
by Renew Life
What is this page for?
First and foremost: checking Gas Stop Enzyme Formula against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Gas Stop Enzyme Formula is a dietary supplement by Renew Life with 8 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.Based on those ingredients, 740 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Fennel. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Gas Stop Enzyme Formula by Renew Life
Ask about any prescription or over-the-counter medication and we check it for interactions with Gas Stop Enzyme Formula by Renew Life — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Gas Stop Enzyme Formula by Renew Life
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Gas Stop Enzyme Formula contains 8 ingredients: the digestive enzymes amylase, protease, lipase, cellulase, and alpha-galactosidase, plus invertase, fennel, and phytase. These enzymes are designed to break down different types of food — carbohydrates, proteins, fats, and fiber — to help reduce gas and bloating.
Fennel is an herb traditionally used to support digestion. The capsule itself is an inactive ingredient.
Does it work?
Not established
The digestive enzymes in this product (protease, lipase, and phytase) have not been rated for effectiveness in our data. Fennel is considered possibly effective for period pain (dysmenorrhea), but evidence for its use in digestive complaints or gas is not established in the data we hold.
For most of the enzyme ingredients, the evidence to support their role in gas relief specifically is insufficient.
How safe is it?
Well-documented data
Protease, lipase, and phytase are generally well tolerated, though they may cause digestive upset in some people and rarely allergic reactions. Fennel is well tolerated as a food, but concentrated supplements carry more caution.
Both protease and phytase have rare reports of allergic reactions in people exposed to airborne powder occupationally. For pregnancy, the safety data advises against medicinal or concentrated fennel due to limited data and its hormone-like effects.
Protease safety has not been established in pregnancy, so it is best avoided unless prescribed. Lipase and phytase have insufficient safety data in pregnancy — talk with your doctor before use.
Breastfeeding safety is similarly uncertain for all these ingredients; check with your healthcare provider first.
Meds to double-check
Moderate interaction found
Before taking Gas Stop Enzyme Formula, double-check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (moderate risk of increased bleeding), birth control pills or estrogen replacement therapy (moderate risk of reduced effectiveness), the antibiotic ciprofloxacin/Cipro (moderate risk of reduced antibiotic effect), medications metabolized by CYP3A4 enzymes in the liver (moderate risk of raised drug levels), or tamoxifen for breast cancer (moderate risk of reduced cancer-drug effect). All of these concerns come from the fennel ingredient.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
This product is designed to ease gas and bloating through digestive enzymes. If you take blood thinners, birth control, estrogen therapy, ciprofloxacin, tamoxifen, or any regular medication, check your exact drugs with your pharmacist or doctor before starting — fennel interactions are a real concern.
If you're pregnant or breastfeeding, the safety data are too limited; talk it over with your doctor or pharmacist first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 27, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Gas Stop Enzyme Formula, straight from the product label.
| Brand | Renew Life |
|---|---|
| Net contents | 60 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jul 27, 2021 |
| DSLD ID | 250889 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Gas Stop Enzyme Formula by Renew Life, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Amylase | 0 NP | -- |
| Protease | 0 NP | -- |
| Lipase | 0 NP | -- |
| Cellulase | 0 NP | -- |
| Invertase | 0 NP | -- |
| Fennel | 0 NP | -- |
| SmartZyme Blend | 680 mg | -- |
| Alpha-Galactosidase | 0 NP | -- |
| Phytase | 0 NP | -- |
Other ingredients: Capsule
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
- Helps prevent ocassional gas and bloating - Helps digest beans and gas-forming foods
Dairy free
Quality, purity, and potency guaranteed through expiration.
Manufactured in USA of global ingredients
Listen to your gut...you'll be glad you did. At Renew Life, we're gut wellness pioneers with double decades of experience and innovation on our side to help keep your gut healthy and help you comfortably enjoy the foods you love.
Renew Life plant-based enzymes work in harmony with your digestive system to reduce occasional digestive discomforts and unlock the nutrient goodness found in your food. Helping you feel lighter, brighter and more energized to take on the day.
FDA Statement of Identity
Enzyme Supplement
Suggested/Recommended/Usage/Directions
Directions: Take two (2) capsules before a meal containing problem food(s).
Precautions
Contains: Wheat and soy traces from fermentation media.
Keep out of reach of children.
Consult your physician prior to using this or any product if you are pregnant, nursing, taking any medication, or have a medical condition.
Warning: This product can expose you to chemicals including lead, which is known to the State of California to cause birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov.
Storage
Store at 77 degrees F (25 degrees C) or below.
Brand IP Statement(s)
Copyright 2018 Patents: www.renewlife.com/patents
General Statements
Visit RenewLife.com for help finding the right product for you. Did you know taking an enzyme before each meal can improve your digestion? Many processed and cooked foods often lack the digestive enzymes found in raw foods, so your body may have to work harder to break down and absorb nutrients. This can cause occasional gas, bloating and indigestion.
Formula
Plant-based enzymes for relief of occasional gas Contains soothing fennel seed to help relax the digestive tract
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Gas Stop Enzyme Formula by Renew Life label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Gas Stop Enzyme Formula by Renew Life
These are the 8 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Other (inactive) ingredients: Capsule. These complete the product’s ingredient list but are not active constituents.
Gas Stop Enzyme Formula by Renew Life Drug Interactions
HelloPharmacist Interaction Report
Gas Stop Enzyme Formula by Renew Life has interactions documented for one of its ingredients: fennel.
The most serious concern is a moderate-severity interaction with blood thinners (anticoagulant and antiplatelet drugs), where fennel may theoretically increase bleeding risk.
Read the full breakdown — every affected drug type, severity by severity
Fennel also carries moderate-severity interactions with birth control pills and estrogen replacement therapy — its estrogenic compounds may reduce their effectiveness — and with the antibiotic ciprofloxacin (Cipro), which fennel may weaken. Additionally, fennel could theoretically raise levels of certain medications metabolized by the liver (CYP3A4 substrates) and interfere with tamoxifen, a breast-cancer drug.
We could not check three other ingredients in this formula: amylase, cellulase, and alpha-galactosidase. Protease, lipase, and phytase have been checked and show no interactions documented in our data — though that is not a guarantee none exist elsewhere.
Altogether, these interactions span 741 individual medications.
Before you start, run your exact medications through the search tool on this page, especially if you take blood thinners, birth control, ciprofloxacin, tamoxifen, or any regular prescription drug.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Gas Stop Enzyme Formula?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Gas Stop Enzyme Formula interact with 740 drugs. Click any drug to see the details.
1 of the 8 ingredients in Gas Stop Enzyme Formula interact with drugs. Each result below shows which ingredient is responsible. Fennel
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fennel + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fennel + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acalabrutinib interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fennel + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fennel + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fennel + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with Gas Stop Enzyme Formula — through 1 ingredient. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Gas Stop Enzyme Formula with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Fennel
Anticoagulant/Antiplatelet Drugs
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Animal research suggests that fennel oil has antithrombotic and antiplatelet effects.
Ciprofloxacin (Cipro)
Theoretically, fennel might decrease the levels and clinical effects of ciprofloxacin.
Animal research shows that fennel reduces ciprofloxacin bioavailability by nearly 50%, possibly due to the metal cations such as calcium, iron, and magnesium contained in fennel. This study also found that fennel increased tissue distribution and slowed elimination of ciprofloxacin.
Contraceptive Drugs
Theoretically, taking large amounts of fennel might decrease the effects of contraceptive drugs due to competition for estrogen receptors.
Some constituents of fennel have estrogenic activity.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
In vitro research suggests that fennel inhibits CYP3A4 enzyme activity. This effect has not been reported in humans.
Estrogens
Theoretically, taking large amounts of fennel might interfere with hormone replacement therapy due to competition for estrogen receptors.
Some constituents of fennel have estrogenic activity.
Tamoxifen (Nolvadex)
Theoretically, taking large amounts of fennel might decrease the antiestrogenic effect of tamoxifen.
Some constituents of fennel have estrogenic activity, which may interfere with the antiestrogenic activity of tamoxifen.
Brand information
Manufacturer and brand details for Gas Stop Enzyme Formula, from the product label.
Renew Life
- Name
- Renew Life Formulas, Inc.
- City
- Palm Harbor
- State
- FL
- ZipCode
- 34683
- Phone Number
- 1-800-830-1800
- Web Address
- www.renewlife.com
Gas Stop Enzyme Formula by Renew Life: Common Questions
Does Gas Stop Enzyme Formula by Renew Life interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What are the digestive enzymes in this formula supposed to do?
Is fennel safe to use while I'm pregnant or breastfeeding?
Can I take this if I'm on birth control?
Is there any evidence this actually works for gas?
What are the most common side effects?
I take a blood thinner — is this product okay?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Gas Stop Enzyme Formula is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Gas Stop Enzyme Formula’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Proteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monographLipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph → Herb & supplement monographFennel
Interacts with 740 drugsFennel is a Mediterranean herb widely used as a food and spice, and traditionally taken for digestive complaints, colic, and menstrual cramps. Some small studies suggest possible benefit for...
Read the full Fennel monograph → Herb & supplement monographPhytase
Phytase is an enzyme that breaks down phytic acid (phytate) found in grains, beans, nuts, and seeds, which can free up minerals like iron, zinc, and calcium for absorption. It is widely used...
Read the full Phytase monograph →Sources & How We Checked
Gas Stop Enzyme Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 28 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Fennel 17 references
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