Ge Gen Alcohol Free Ingredients & Drug Interactions
by Hawaii Pharm
What is this page for?
First and foremost: checking Ge Gen Alcohol Free against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Ge Gen Alcohol Free is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for alcohol cravings and reduction, menopausal symptoms, heart and blood vessel health.Based on those ingredients, 584 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Pueraria lobata Root Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Ge Gen Alcohol Free by Hawaii Pharm
Ask about any prescription or over-the-counter medication and we check it for interactions with Ge Gen Alcohol Free by Hawaii Pharm — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Ge Gen Alcohol Free by Hawaii Pharm
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: Pueraria lobata (kudzu) root extract in a dry form. Kudzu has a long history in traditional medicine and is used here as an alcohol-free liquid—the inactive ingredients are glycerin and water.
Does it work?
Moderate evidence
The evidence supports kudzu as possibly effective for alcohol use disorder. For other uses listed—hay fever (allergic rhinitis), angina, and back pain—the evidence we hold is insufficient to rate whether it works.
If you're considering this product for one of those conditions, the science isn't settled yet.
How safe is it?
Well-documented data
Kudzu is generally well tolerated in short-term studies, but we don't have solid data on long-term safety. In clinical trials, some people reported nausea, indigestion, bloating, dizziness, and skin reactions (hives or rash), though these didn't occur more often than placebo.
There's one case report of a more widespread allergic rash after taking a combination product containing kudzu. The safety data advises against use during pregnancy because of insufficient data and possible hormone-like effects.
There's also too little safety information to recommend it while breastfeeding. If you're pregnant, planning to become pregnant, or nursing, talk with your doctor or pharmacist before taking this product.
Meds to double-check
Moderate interaction found
Before taking this product, check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (warfarin, clopidogrel, aspirin at high doses), drugs that affect the liver, estrogen or birth control, tamoxifen, methotrexate, diabetes medications, or caffeine supplements. These carry Moderate to Minor interaction risks with kudzu.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
Kudzu may help with alcohol use disorder, but it interacts with blood thinners, diabetes drugs, estrogen therapy, methotrexate, caffeine, and drugs that stress the liver—a broad list. It's generally well tolerated short-term, but long-term safety isn't established.
If you take any regular medications, check them against the interaction tool here, then discuss this product with your own doctor or pharmacist before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 24, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Ge Gen Alcohol Free, straight from the product label.
| Brand | Hawaii Pharm |
|---|---|
| Barcode (UPC) | 840253623683 |
| Net contents | 4 Fluid Ounce(s); 120 mL |
| Market status | On market |
| Date entered into DSLD | Aug 24, 2023 |
| DSLD ID | 300714 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Ge Gen Alcohol Free by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Pueraria lobata Root Extract, Dry | 1156 mg | -- |
Other ingredients: Glycerin, Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
Hawaii Pharm Herbal Extract Highest quality since 2008
Suggested/Recommended/Usage/Directions
Suggested use: Shake well before using. For adults add about 20-30 drops (0.7-1 mL, one full squeeze of the dropper bulb) to some juice or water, up to 4 times a day.
Precautions
Warning: We recommend to seek expert medical advice before taking.
Do not use if you are allergic to any ingredients.
Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.
Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.
May affect the ability to drive and operate machinery. May have contraindications, can cause side effects and adverse reactions. Do not use if seal is broken or missing.
Keep out of the reach of children!
Storage
Store in a cool dry place.
Seals/Symbols
cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.
C2H5OH Alcohol free USA Made in United States of America
FDA Disclaimer Statement
This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.
General Statements
Scan this QR-code to get 15% discount on your next purchase. Limited time deal.
Formula
Pueraria lobata
Formulation
Only natural ingredients Purity is laboratory tested and verified
All the raw materials are gluten-free by their nature No artificial colors, flavors, or preservatives
Not tested on animals
C2H5OH Alcohol free
Made in USA, Hawaii
FDA Statement of Identity
Herbal Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Ge Gen Alcohol Free by Hawaii Pharm label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Ge Gen Alcohol Free by Hawaii Pharm
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.
Pueraria lobata Root Extract, Dry
Interacts with584 drugs
Kudzu is a fast-growing vine whose root has long been used in traditional Chinese medicine and is now studied mostly for reducing alcohol intake. Earl...
Pueraria lobata Root Extract, Dry monograph & interactionsOther (inactive) ingredients: Glycerin, Water. These complete the product’s ingredient list but are not active constituents.
Ge Gen Alcohol Free by Hawaii Pharm Drug Interactions
HelloPharmacist Interaction Report
Ge Gen Alcohol Free by Hawaii Pharm contains kudzu root extract, which interacts with a notable range of medications.
The most serious concern is with blood thinners and antiplatelet drugs (anticoagulants/antiplatelet drugs)—kudzu's isoflavones may increase bleeding risk, a Moderate severity interaction.
Read the full breakdown — every affected drug type, severity by severity
Additionally, kudzu may affect how your liver processes several drug types. It could add to the liver stress of hepatotoxic drugs, interfere with methotrexate elimination and raise its toxicity risk, and slow caffeine clearance—all Moderate severity.
Estrogen-based medications (including birth control and hormone therapy) and tamoxifen for breast cancer may also be affected, since kudzu appears to have estrogenic properties. Finally, diabetes medications carry a Minor interaction risk; kudzu might lower blood sugar further, raising hypoglycemia risk.
Altogether, these interactions span 585 individual medications. Use the medication checker on this page to look up your exact prescriptions before starting this product.
If you take any of these drug types, talk with your doctor or pharmacist first.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Ge Gen Alcohol Free?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Ge Gen Alcohol Free interact with 584 drugs. Click any drug to see the details.
1 of the 1 ingredient in Ge Gen Alcohol Free interact with drugs. Each result below shows which ingredient is responsible. Pueraria lobata Root Extract, Dry
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract, Dry + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract, Dry + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract, Dry + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.
Read the full Pueraria Lobata Root Extract, Dry + Abciximab interactionAbiraterone
How Abiraterone interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract, Dry + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract, Dry + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.
Read the full Pueraria Lobata Root Extract, Dry + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryAntidiabetes Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking kudzu with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Pueraria Lobata Root Extract, Dry + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract, Dry + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.
Read the full Pueraria Lobata Root Extract, Dry + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract, Dry + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryHepatotoxic Drugs, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract, Dry + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryAnticoagulant/antiplatelet Drugs, Hepatotoxic Drugs +1 Moderate
Interaction Summary
Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.
Read the full Pueraria Lobata Root Extract, Dry + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract, Dry + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract, Dry + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryHepatotoxic Drugs, Caffeine Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract, Dry + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryCaffeine, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking kudzu with caffeine might increase levels of caffeine.
Read the full Pueraria Lobata Root Extract, Dry + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract, Dry + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract, Dry + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryHepatotoxic Drugs, Caffeine Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract, Dry + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryCaffeine, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking kudzu with caffeine might increase levels of caffeine.
Read the full Pueraria Lobata Root Extract, Dry + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryHepatotoxic Drugs, Caffeine Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract, Dry + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryCaffeine, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking kudzu with caffeine might increase levels of caffeine.
Read the full Pueraria Lobata Root Extract, Dry + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryHepatotoxic Drugs, Caffeine Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract, Dry + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryCaffeine, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking kudzu with caffeine might increase levels of caffeine.
Read the full Pueraria Lobata Root Extract, Dry + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract, Dry + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract, Dry + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract, Dry + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract, Dry + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Ge Gen Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root Extract, DryHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract, Dry + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Ge Gen Alcohol Free with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Pueraria lobata Root Extract, Dry
Anticoagulant/Antiplatelet Drugs
Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.
Kudzu isoflavones are reported to have antiplatelet activity.
Caffeine
Theoretically, taking kudzu with caffeine might increase levels of caffeine.
In healthy males injected with the kudzu constituent puerarin, caffeine clearance and metabolism is inhibited. This effect has been attributed to inhibition of cytochrome P450 1A2 (CYP1A2) enzyme, which is involved in caffeine metabolism. It is unclear if taking kudzu orally would have this same effect.
Estrogens
Theoretically, kudzu might alter the effects of estrogen therapy.
Some research suggests that kudzu has estrogenic effects. This may enhance or inhibit the effects of estrogen therapy.
Hepatotoxic Drugs
Theoretically, concomitant use might have additive hepatotoxic effects.
There is some concern that kudzu can adversely affect the liver.
Methotrexate (Trexall, Others)
Theoretically, taking kudzu with methotrexate might increase the risk of methotrexate toxicity.
Preclinical research suggests that kudzu extract greatly reduces the elimination and increases the toxicity of methotrexate. Kudzu might inhibit organic anion transporters (OATs) that are responsible for hepatobiliary and renal excretion of anions, similar to the interaction between methotrexate and non-steroidal anti-inflammatory drugs (NSAIDs).
Tamoxifen (Nolvadex)
Theoretically, kudzu might interfere with tamoxifen activity.
Some research suggests that kudzu may have estrogenic effects.
Antidiabetes Drugs
Theoretically, taking kudzu with antidiabetes drugs might increase the risk of hypoglycemia.
Kudzu might lower blood glucose levels and have additive effects in patients treated with antidiabetic agents. The dose of diabetes medications might need to be adjusted.
Brand information
Manufacturer and brand details for Ge Gen Alcohol Free, from the product label.
Hawaii Pharm
See all Hawaii Pharm products- Name
- Hawaii Pharm LLC
- Street Address
- 510 Sumner St. Ste. 613
- City
- Honolulu
- State
- HI
- ZipCode
- 96817
- Phone Number
- 888-854-2924
- Web Address
- www.hawaiipharm.com
Ge Gen Alcohol Free by Hawaii Pharm: Common Questions
Does Ge Gen Alcohol Free by Hawaii Pharm interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm on birth control or hormone therapy?
What side effects might I experience?
Is this safe to use long-term?
Can I take this while pregnant or breastfeeding?
Does kudzu actually help with drinking problems?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Ge Gen Alcohol Free is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Ge Gen Alcohol Free’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Ge Gen Alcohol Free's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 21 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Kudzu 21 references
- Woo J, Lau E, Ho SC, et al. Comparison of Pueraria lobata with hormone replacement therapy in treating the adverse health consequences of menopause. Menopause 2003;10:352-61. PubMed
- Akita H, Sowa J, Makiura M, et al. Maculopapular drug eruption due to the Japanese herbal medicine Kakkonto (kudzu or arrowroot decoction). Contact Dermatitis 2003;48:348-9. PubMed
- Luo ZR, Zheng B. [Effect of Puerarin on platelet activating factors CD63 and CD62P, plasminogen activator inhibitor and C-reactive protein in patients with unstable angia pectoris]. Zhongguo Zhong Xi Yi Jie He Za Zhi 2001;21:31-3 .
- Lee KT, Sohn IC, Kim DH, et al. Hypoglycemic and hypolipidemic effects of tectorigenin and kaikasaponin III in the streptozotocin-lnduced diabetic rat and their antioxidant activity in vitro. Arch Pharm Res 2000;23:461-6.
- Yu Z, Zhang G, Zhao H. [Effects of Puerariae isoflavone on blood viscosity, thrombosis and platelet function]. Zhong Yao Cai 1997;20:468-9.
- Hsu FL, Liu IM, Kuo DH, et al. Antihyperglycemic effect of puerarin in streptozotocin-induced diabetic rats. J Nat Prod 2003;66:788-92. PubMed
- Chiang HM, Fang SH, Wen KC, et al. Life-threatening interaction between the root extract of Pueraria lobata and methotrexate in rats. Toxicol Appl Pharmacol 2005;209:263-8.
- Zheng, J., Chen, B., Jiang, B., Zeng, L., Tang, Z. R., Fan, L., and Zhou, H. H. The effects of puerarin on CYP2D6 and CYP1A2 activities in vivo. Arch Pharm Res 2010;33(2):243-246. PubMed
- Hsu, H. H., Chang, C. K., Su, H. C., Liu, I. M., and Cheng, J. T. Stimulatory effect of puerarin on alpha1A-adrenoceptor to increase glucose uptake into cultured C2C12 cells of mice. Planta Med 2002;68(11):999-1003.
- Zheng, G., Zhang, X., Zheng, J., Meng, Q., and Zheng, D. [Estrogen-like effects of puerarin and total isoflavones from Pueraria lobata]. Zhong.Yao Cai. 2002;25(8):566-568.
- Qi, B. L. and Qi, B. M. [Effect of the purariae-isofiavones on estrogen level in normal and ovariectomized rats]. Zhongguo Zhong.Yao Za Zhi. 2002;27(11):850-852.
- Akita, H., Sowa, J., Makiura, M., Akamatsu, H., and Matsunaga, K. Maculopapular drug eruption due to the Japanese herbal medicine Kakkonto (kudzu or arrowroot decoction). Contact Dermatitis 2003;48(6):348-349. PubMed
- Manonai, J., Chittacharoen, A., Theppisai, U., and Theppisai, H. Effect of Pueraria mirifica on vaginal health. Menopause. 2007;14(5):919-924. PubMed
- Chandeying, V. and Sangthawan, M. Efficacy comparison of Pueraria mirifica (PM) against conjugated equine estrogen (CEE) with/without medroxyprogesterone acetate (MPA) in the treatment of climacteric symptoms in perimenopausal women: phase III study. J M
- Virojchaiwong, P., Suvithayasiri, V., and Itharat, A. Comparison of Pueraria mirifica 25 and 50 mg for menopausal symptoms. Arch.Gynecol.Obstet. 2011;284(2):411-419. PubMed
- Hou, Q., Ao, X., Li, G., and Zhang, Y. [Puerarin combined with avandia for diabetic nephropathy]. Zhong.Nan.Da.Xue Xue Bao Yi Xue Ban. 2012;37(1):73-77.
- Kim HJ, Kim H, Ahn JH, Suk JH. Liver injury induced by herbal extracts containing mistletoe and kudzu. J Altern Complement Med 2015;21(3):180-5. PubMed
- Santosh N, Mohan K, Royana S, Yamini TB. Hepatotoxicity of tubers of Indian Kudzu (Pueraria tuberosa) in rats. Food Chem Toxicol. 2010 Apr;48(4):1066-71. PubMed
- Teschke R, Zhang L, Long H, Schwarzenboeck A, Schmidt-Taenzer W, Genthner A, Wolff A, Frenzel C, Schulze J, Eickhoff A. Traditional Chinese Medicine and herbal hepatotoxicity: a tabular compilation of reported cases. Ann Hepatol. 2015 Jan-Feb;14(1):7-19. DOI
- Wang D, Qiu L, Wu X, Wei H, Xu F. Evaluation of kudzu root extract-induced hepatotoxicity. J Ethnopharmacol. 2015 Dec 24;176:321-6. PubMed
- Warinsiriruk P, Tantitham C, Cherdshewasart W, Shobeiri SA, Manonai J. Effects of Pueraria mirifica on vaginal artery vascularization in postmenopausal women with genitourinary syndrome of menopause. Maturitas 2022;160:4-10. PubMed
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