Ginseng Immune Health Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Ginseng Immune Health against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Ginseng Immune Health is a dietary supplement by Puritan's Pride with 2 active ingredients. Its ingredients are commonly taken for body and breath odor control, wound and skin care, internal deodorant for ostomy or incontinence.Based on those ingredients, 1,291 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Asian Ginseng extract, Sodium Copper Chlorophyllin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Ginseng Immune Health by Puritan's Pride
Ask about any prescription or over-the-counter medication and we check it for interactions with Ginseng Immune Health by Puritan's Pride — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Ginseng Immune Health by Puritan's Pride
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Ginseng Immune Health contains 2 active ingredients: sodium copper chlorophyllin and Asian ginseng extract. The softgels also include inactive ingredients—soybean oil, gelatin, glycerin, yellow beeswax, palm oil, coconut oil, and a few other excipients.
Does it work?
Moderate evidence
The evidence is mixed and limited for both ingredients. Asian ginseng shows possibly effective ratings for erectile dysfunction, sexual arousal, cognitive function, multiple sclerosis-related fatigue, and a possible role in influenza; it's been studied short-term in healthy adults, but long-term safety evidence is sparse.
For sodium copper chlorophyllin, the data is much thinner—there's insufficient reliable evidence for acne, cancer, constipation, flatulence, and low white blood cell count, and it's actually rated possibly ineffective for urinary odor.
How safe is it?
Well-documented data
Both ingredients are generally well tolerated short-term, but long-term safety data are limited. Sodium copper chlorophyllin should be avoided during pregnancy and breastfeeding due to insufficient safety data.
Asian ginseng is rated possibly unsafe in pregnancy and safety while breastfeeding is unknown, so avoidance is the safer choice during both. The most common side effect of ginseng is insomnia; headache, dizziness, euphoria, and mania have also been reported.
In rare cases, anaphylaxis, arrhythmias, and Stevens-Johnson syndrome have occurred. Chlorophyllin can cause photosensitization and, in case reports, has been linked to pseudoporphyria (a blistering condition) with oral use.
Meds to double-check
Moderate interaction found
Before taking this product, check with your doctor or pharmacist if you take insulin (risk of low blood sugar), any sedatives like midazolam, drugs broken down by the liver enzyme CYP2D6, furosemide (a water pill), monoamine oxidase inhibitors (MAOIs—older antidepressants), selegiline (Parkinson's medication), raltegravir (HIV medication), warfarin (a blood thinner), or any medications that increase sun sensitivity. Altogether, these interactions span 1,292 individual medications—use the search tool on this page to verify your exact prescriptions.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product pairs two ingredients with limited long-term safety evidence and a significant interaction profile—especially if you take insulin, sedatives, blood thinners, water pills, certain antidepressants, or HIV or Parkinson's medications. The ginseng may help with sexual function or cognitive function in the short term, but chlorophyllin's effectiveness is largely unproven.
Talk with your doctor or pharmacist before starting, particularly if you're on any regular medications or are pregnant or breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Ginseng Immune Health, straight from the product label.
| Brand | Puritan's Pride |
|---|---|
| Barcode (UPC) | 021130785896 |
| Net contents | 60 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Mar 24, 2017 |
| DSLD ID | 71844 |
| Product type | Other Combinations |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Ginseng Immune Health by Puritan's Pride, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Sodium Copper Chlorophyllin | 122 mcg | -- |
| Asian Ginseng extract | 200 mg | -- |
Other ingredients: Soybean Oil, Gelatin, Glycerin, yellow Beeswax, Palm Oil, Coconut Oil, Contains <2% of:
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
Dietary Supplement
General Statements
www.puritan.com Item #30139
State-of-the-art manufacturing and packaging facilities ensure you the highest quality nutritional supplements money can buy. When it comes to your health...choose the best.
Suggested/Recommended/Usage/Directions
Suggested Use: Take two (2) softgels daily, preferably with a meal or as directed by a healthcare practitioner.
Formula
Contains soy ingredients.
Precautions
Contains soy ingredients.
Warning: Not intended for use by pregnant or nursing women. If you are taking any medications or have any medical condition, consult your doctor before use.
Discontinue use and consult your doctor if any adverse reactions occur.
Not intended for use by persons under the age of 18. Keep out of reach of children.
Do not use if seal under cap is broken or missing.
Formulation
No artificial flavor, no preservatives, no sugar, no starch, no milk, no lactose, no gluten, no wheat, no yeast, no fish.
Brand IP Statement(s)
Puritan's Pride supplements are produced from the finest raw materials under stringent quality control standards.
2016 Puritan’s Pride, Inc.
Storage
Store at room temperature.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General
Item #30139 B34101 00A
Seals/Symbols
QA Quality Assured
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Ginseng Immune Health by Puritan's Pride label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Ginseng Immune Health by Puritan's Pride
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Sodium Copper Chlorophyllin
Interacts with335 drugs
Chlorophyllin is a water-soluble, semi-synthetic form of chlorophyll most often used to help control body and fecal odor and to support wound healing....
Sodium Copper Chlorophyllin monograph & interactionsAsian Ginseng extract
Interacts with1,130 drugs
Panax ginseng is a popular traditional herb used to boost energy, ease stress, and support overall wellness, though scientific evidence is mixed and m...
Asian Ginseng extract monograph & interactionsOther (inactive) ingredients: Soybean Oil, Gelatin, Glycerin, Yellow Beeswax, Palm Oil, Coconut Oil, Contains <2% of:. These complete the product’s ingredient list but are not active constituents.
Ginseng Immune Health by Puritan's Pride Drug Interactions
HelloPharmacist Interaction Report
Ginseng Immune Health by Puritan's Pride contains two active ingredients—sodium copper chlorophyllin and Asian ginseng extract—that together interact with a substantial number of medications.
The most serious concern is with Asian ginseng and insulin: taking ginseng with insulin may increase the risk of low blood sugar (hypoglycemia), and your insulin dose might need adjustment.
Read the full breakdown — every affected drug type, severity by severity
African ginseng also has moderate interactions with several other drug types. It may speed up how your body clears midazolam (a sedative), reducing its effectiveness.
It can interfere with drugs broken down by the liver enzyme CYP2D6—a large class that includes many common medications—and may reduce the effect of furosemide (a water pill). Additionally, ginseng shouldn't be combined with monoamine oxidase inhibitors (MAOIs, older antidepressants), as it can trigger insomnia, headache, tremors, and mood changes.
It may also affect selegiline (an older Parkinson's drug) and increase levels of raltegravir (an HIV medication), raising the risk of liver damage. There's a single case report of ginseng reducing warfarin's (a blood thinner) effectiveness, though this interaction is considered unlikely.
Sodium copper chlorophyllin carries a moderate interaction with photosensitizing drugs—medications that make your skin more sensitive to sunlight—because chlorophyllin itself can cause photosensitization and may have additive effects.
Altogether, these interactions span 1,292 individual medications. Use the medication checker on this page to look up your specific prescriptions before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Ginseng Immune Health?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Ginseng Immune Health interact with 1,291 drugs. Click any drug to see the details.
2 of the 2 ingredients in Ginseng Immune Health interact with drugs. Each result below shows which ingredient is responsible. Asian Ginseng extract Sodium Copper Chlorophyllin
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Ginseng Immune Health — through 1 ingredient. Tap an ingredient for the detail:
Asian Ginseng ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, Panax ginseng use might interfere with immunosuppressive therapy.
Read the full Asian Ginseng Extract + 6-mercaptopurine interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Ginseng Immune Health — through 1 ingredient. Tap an ingredient for the detail:
Asian Ginseng ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Panax ginseng might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Asian Ginseng Extract + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Ginseng Immune Health — through 1 ingredient. Tap an ingredient for the detail:
Asian Ginseng ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Although Panax ginseng has shown antiplatelet effects in the laboratory, it is unlikely to increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Asian Ginseng Extract + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Ginseng Immune Health — through 1 ingredient. Tap an ingredient for the detail:
Asian Ginseng ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Panax ginseng might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Asian Ginseng Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Ginseng Immune Health — through 1 ingredient. Tap an ingredient for the detail:
Asian Ginseng ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Panax ginseng might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Asian Ginseng Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Ginseng Immune Health — through 1 ingredient. Tap an ingredient for the detail:
Asian Ginseng ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Panax ginseng might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Asian Ginseng Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Ginseng Immune Health — through 1 ingredient. Tap an ingredient for the detail:
Asian Ginseng ExtractImmunosuppressants, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, Panax ginseng use might interfere with immunosuppressive therapy.
Read the full Asian Ginseng Extract + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Ginseng Immune Health — through 1 ingredient. Tap an ingredient for the detail:
Asian Ginseng ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Panax ginseng might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Asian Ginseng Extract + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Ginseng Immune Health — through 1 ingredient. Tap an ingredient for the detail:
Asian Ginseng ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking Panax ginseng with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Asian Ginseng Extract + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Ginseng Immune Health — through 1 ingredient. Tap an ingredient for the detail:
Asian Ginseng ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Although Panax ginseng has shown antiplatelet effects in the laboratory, it is unlikely to increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Asian Ginseng Extract + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Ginseng Immune Health — through 1 ingredient. Tap an ingredient for the detail:
Sodium Copper ChlorophyllinPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyllin with photosensitizing drugs may have additive effects.
Read the full Sodium Copper Chlorophyllin + Acepromazine interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Ginseng Immune Health — through 1 ingredient. Tap an ingredient for the detail:
Asian Ginseng ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Although Panax ginseng has shown antiplatelet effects in the laboratory, it is unlikely to increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Asian Ginseng Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Ginseng Immune Health — through 1 ingredient. Tap an ingredient for the detail:
Asian Ginseng ExtractAnticoagulant/antiplatelet Drugs, Stimulant Drugs +2 Moderate
Interaction Summary
Although Panax ginseng has shown antiplatelet effects in the laboratory, it is unlikely to increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Asian Ginseng Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Ginseng Immune Health — through 2 ingredients. Tap an ingredient for the detail:
Asian Ginseng ExtractStimulant Drugs Moderate
Interaction Summary
Theoretically, taking Panax ginseng with stimulant drugs might increase the risk of adverse stimulant effects.
Read the full Asian Ginseng Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionSodium Copper ChlorophyllinPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyllin with photosensitizing drugs may have additive effects.
Read the full Sodium Copper Chlorophyllin + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Ginseng Immune Health — through 1 ingredient. Tap an ingredient for the detail:
Asian Ginseng ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Caffeine +1 Moderate
Interaction Summary
Theoretically, Panax ginseng might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Asian Ginseng Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Ginseng Immune Health — through 1 ingredient. Tap an ingredient for the detail:
Asian Ginseng ExtractStimulant Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Theoretically, taking Panax ginseng with stimulant drugs might increase the risk of adverse stimulant effects.
Read the full Asian Ginseng Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Ginseng Immune Health — through 1 ingredient. Tap an ingredient for the detail:
Asian Ginseng ExtractCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Panax ginseng might increase levels of drugs metabolized by CYP2D6.
Read the full Asian Ginseng Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Ginseng Immune Health — through 1 ingredient. Tap an ingredient for the detail:
Asian Ginseng ExtractCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Panax ginseng might increase levels of drugs metabolized by CYP2D6.
Read the full Asian Ginseng Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Ginseng Immune Health — through 2 ingredients. Tap an ingredient for the detail:
Asian Ginseng ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Theoretically, Panax ginseng might increase levels of drugs metabolized by CYP2D6.
Read the full Asian Ginseng Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionSodium Copper ChlorophyllinPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyllin with photosensitizing drugs may have additive effects.
Read the full Sodium Copper Chlorophyllin + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Ginseng Immune Health — through 1 ingredient. Tap an ingredient for the detail:
Asian Ginseng ExtractCaffeine, Stimulant Drugs +2 Moderate
Interaction Summary
Theoretically, taking Panax ginseng with caffeine might increase the risk of adverse stimulant effects.
Read the full Asian Ginseng Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Ginseng Immune Health — through 1 ingredient. Tap an ingredient for the detail:
Asian Ginseng ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Theoretically, Panax ginseng might increase levels of drugs metabolized by CYP2D6.
Read the full Asian Ginseng Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Ginseng Immune Health — through 1 ingredient. Tap an ingredient for the detail:
Asian Ginseng ExtractCaffeine, Stimulant Drugs +2 Moderate
Interaction Summary
Theoretically, taking Panax ginseng with caffeine might increase the risk of adverse stimulant effects.
Read the full Asian Ginseng Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Ginseng Immune Health — through 1 ingredient. Tap an ingredient for the detail:
Asian Ginseng ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Stimulant Drugs +1 Moderate
Interaction Summary
Theoretically, Panax ginseng might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Asian Ginseng Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Ginseng Immune Health — through 1 ingredient. Tap an ingredient for the detail:
Asian Ginseng ExtractCaffeine, Stimulant Drugs +1 Moderate
Interaction Summary
Theoretically, taking Panax ginseng with caffeine might increase the risk of adverse stimulant effects.
Read the full Asian Ginseng Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Ginseng Immune Health — through 2 ingredients. Tap an ingredient for the detail:
Sodium Copper ChlorophyllinPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyllin with photosensitizing drugs may have additive effects.
Read the full Sodium Copper Chlorophyllin + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAsian Ginseng ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Panax ginseng might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Asian Ginseng Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Ginseng Immune Health — through 2 ingredients. Tap an ingredient for the detail:
Asian Ginseng ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Stimulant Drugs +1 Moderate
Interaction Summary
Theoretically, Panax ginseng might increase levels of drugs metabolized by CYP2D6.
Read the full Asian Ginseng Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionSodium Copper ChlorophyllinPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyllin with photosensitizing drugs may have additive effects.
Read the full Sodium Copper Chlorophyllin + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Ginseng Immune Health — through 2 ingredients. Tap an ingredient for the detail:
Asian Ginseng ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Panax ginseng might increase levels of drugs metabolized by CYP2D6.
Read the full Asian Ginseng Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionSodium Copper ChlorophyllinPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyllin with photosensitizing drugs may have additive effects.
Read the full Sodium Copper Chlorophyllin + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Ginseng Immune Health — through 2 ingredients. Tap an ingredient for the detail:
Asian Ginseng ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Panax ginseng might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Asian Ginseng Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionSodium Copper ChlorophyllinPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyllin with photosensitizing drugs may have additive effects.
Read the full Sodium Copper Chlorophyllin + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Ginseng Immune Health — through 2 ingredients. Tap an ingredient for the detail:
Asian Ginseng ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Stimulant Drugs +1 Moderate
Interaction Summary
Theoretically, Panax ginseng might increase levels of drugs metabolized by CYP2D6.
Read the full Asian Ginseng Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionSodium Copper ChlorophyllinPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyllin with photosensitizing drugs may have additive effects.
Read the full Sodium Copper Chlorophyllin + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Ginseng Immune Health — through 2 ingredients. Tap an ingredient for the detail:
Asian Ginseng ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Stimulant Drugs +1 Moderate
Interaction Summary
Theoretically, Panax ginseng might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Asian Ginseng Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionSodium Copper ChlorophyllinPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyllin with photosensitizing drugs may have additive effects.
Read the full Sodium Copper Chlorophyllin + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Ginseng Immune Health with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Asian Ginseng extract
Anticoagulant/Antiplatelet Drugs
Although Panax ginseng has shown antiplatelet effects in the laboratory, it is unlikely to increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro evidence suggests that ginsenoside constituents in Panax ginseng might decrease platelet aggregation. However, research in humans suggests that ginseng does not affect platelet aggregation. Animal research indicates low oral bioavailability of Rb1 and rapid elimination of Rg1, which might explain the discrepancy between in vitro and human research. Until more is known, use with caution in patients concurrently taking anticoagulant or antiplatelet drugs.
Antidiabetes Drugs
Theoretically, taking Panax ginseng with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research suggests that Panax ginseng might decrease blood glucose levels. Monitor blood glucose levels closely.
Caffeine
Theoretically, taking Panax ginseng with caffeine might increase the risk of adverse stimulant effects.
Panax ginseng has been shown to have stimulant effects. Theoretically, caffeine might have an additive effect on the stimulant effects of Panax ginseng.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, Panax ginseng might increase levels of drugs metabolized by CYP2D6. However, research is conflicting.
There is some evidence that Panax ginseng can inhibit the CYP2D6 enzyme by approximately 6%. In addition, in animal research, Panax ginseng inhibits the metabolism of dextromethorphan, a drug metabolized by CYP2D6, by a small amount. However, contradictory research suggests Panax ginseng might not inhibit CYP2D6. Until more is known, use Panax ginseng cautiously in patients taking drugs metabolized by these enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, Panax ginseng might increase or decrease levels of drugs metabolized by CYP3A4.
Panax ginseng may affect the clearance of drugs metabolized by CYP3A4. One such drug is imatinib. Inhibition of CYP3A4 was believed to be responsible for a case of imatinib-induced hepatotoxicity. In contrast, Panax ginseng has been shown to increase the clearance of midazolam, another drug metabolized by CYP3A4. Clinical research shows that Panax ginseng can reduce midazolam area under the curve by 44%, maximum plasma concentration by 26%, and time to reach maximum plasma concentration by 29%. Midazolam metabolism was also increased in animals given Panax ginseng. Until more is known, use Panax ginseng cautiously in combination with CYP3A4 substrates.
Estrogens
Theoretically, concomitant use of large amounts of Panax ginseng might interfere with hormone replacement therapy.
Laboratory research and some case reports suggest that Panax ginseng can have estrogenic effects due to competition for estrogen receptors. The estrogenic activity is attributed to the ginsenoside constituents of Panax ginseng.
Furosemide (Lasix)
Theoretically, Panax ginseng might reduce the effects of furosemide.
There is some concern that Panax ginseng might contribute to furosemide resistance. There is one case of resistance to furosemide diuresis in a patient taking a germanium-containing ginseng product.
Imatinib (Gleevec)
Theoretically, Panax ginseng might increase the effects and adverse effects of imatinib.
A case of imatinib-induced hepatotoxicity has been reported for a 26-year-old male with chronic myelogenous leukemia stabilized on imatinib for 7 years. The patient took imatinib 400 mg along with a Panax ginseng-containing energy drink daily for 3 months. Since imatinib-associated hepatotoxicity typically occurs within 2 years of initiating therapy, it is believed that Panax ginseng affected imatinib toxicity though inhibition of cytochrome P450 3A4. CYP3A4 is the primary enzyme involved in imatinib metabolism.
Immunosuppressants
Theoretically, Panax ginseng use might interfere with immunosuppressive therapy.
Panax ginseng might have immune system stimulating properties.
Insulin
Theoretically, taking Panax ginseng with insulin might increase the risk of hypoglycemia.
Clinical research suggests that Panax ginseng might decrease blood glucose levels. Insulin dose adjustments might be necessary in patients taking Panax ginseng; use with caution.
Midazolam (Versed)
Theoretically, Panax ginseng may increase the clearance of midazolam.
Midazolam is metabolized by cytochrome P450 3A4 (CYP3A4). Clinical research suggests that Panax ginseng can reduce midazolam area under the curve by 44%, maximum plasma concentration by 26%, and time to reach maximum plasma concentration by 29%. Midazolam metabolism was also increased in animals given Panax ginseng.
Monoamine Oxidase Inhibitors (Maois)
Theoretically, Panax ginseng can interfere with MAOI therapy.
Concomitant use of Panax ginseng with phenelzine (Nardil) is associated with insomnia, headache, tremors, and hypomania.
Nifedipine (Procardia)
Theoretically, taking Panax ginseng with nifedipine might increase serum levels of nifedipine and the risk of hypotension.
Preliminary clinical research shows that concomitant use can increase serum levels of nifedipine in healthy volunteers. This might cause the blood pressure lowering effects of nifedipine to be increased when taken concomitantly with Panax ginseng.
Qt Interval-Prolonging Drugs
Theoretically, Panax ginseng has an additive effect with drugs that prolong the QT interval and potentially increase the risk of ventricular arrhythmias. However, research is conflicting.
Clinical research shows that short-term use of Panax ginseng can increase the QT interval. However, no changes in QT interval have been identified with prolonged use.
Raltegravir (Isentress)
Theoretically, taking Panax ginseng with raltegravir might increase the risk of liver toxicity.
A case report suggests that concomitant use of Panax ginseng with raltegravir can increase serum levels of raltegravir, resulting in elevated liver enzymes levels.
Selegiline (Eldepryl)
Theoretically, Panax ginseng might increase or decrease levels of selegiline, possibly altering the effects and side effects of selegiline.
Animal research shows that taking selegiline with a low dose of Panax ginseng extract (1 gram/kg) reduces selegiline bioavailability, while taking a high dose of Panax ginseng extract (3 grams/kg) increases selegiline bioavailability. More research is needed to confirm these effects.
Stimulant Drugs
Theoretically, taking Panax ginseng with stimulant drugs might increase the risk of adverse stimulant effects.
Panax ginseng has been shown to have stimulant effects.
Warfarin (Coumadin)
Panax ginseng might affect the clearance of warfarin. However, this interaction appears to be unlikely.
There has been a single case report of decreased effectiveness of warfarin in a patient who also took Panax ginseng. However, it is questionable whether Panax ginseng was the cause of this decrease in warfarin effectiveness. Some research in humans and animals suggests that Panax ginseng does not affect the pharmacokinetics of warfarin. However, other research in humans suggests that Panax ginseng might modestly increase the clearance of the S-warfarin isomer. More evidence is needed to determine whether Panax ginseng causes a significant interaction with warfarin.
Fexofenadine (Allegra)
Theoretically, Panax ginseng might decrease blood levels of oral or intravenous fexofenadine.
Animal research suggests that taking Panax ginseng in combination with oral or intravenous fexofenadine may reduce the bioavailability of fexofenadine. Some scientists have attributed this effect to the ability of Panax ginseng to increase the expression of P-glycoprotein.
Lopinavir/Ritonavir (Kaletra)
Although Panax ginseng has demonstrated variable effects on cytochrome P450 3A4 (CYP3A4), which metabolizes lopinavir, Panax ginseng is unlikely to alter levels of lopinavir/ritonavir.
Lopinavir is metabolized by CYP3A4 and is administered with the CYP3A4 inhibitor ritonavir to increase its plasma concentrations. Panax ginseng has shown variable effects on CYP3A4 activity in humans. However, taking Panax ginseng (Vitamer Laboratories) 500 mg twice daily for 14 days did not alter the pharmacokinetics of lopinavir/ritonavir in 12 healthy volunteers.
Sodium Copper Chlorophyllin
Photosensitizing Drugs
Theoretically, concomitant use of chlorophyllin with photosensitizing drugs may have additive effects.
Chlorophyllin is a semi-synthetic derivative of chlorophyll. Chlorophyll has been reported to cause photosensitization. Orally, chlorophyll has also been associated with the development of pseudoporphyria in multiple case reports.
Brand information
Manufacturer and brand details for Ginseng Immune Health, from the product label.
Puritan's Pride
See all Puritan's Pride products- Name
- Puritan's Pride, Inc.
- City
- Ronkonkoma
- State
- NY
- ZipCode
- 11779
- Phone Number
- 1-800-645-1030
- Web Address
- www.puritan.com
Ginseng Immune Health by Puritan's Pride: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Ginseng Immune Health’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Chlorophyllin
Interacts with 335 drugsChlorophyllin is a water-soluble, semi-synthetic form of chlorophyll most often used to help control body and fecal odor and to support wound healing. The best evidence is for its use as a d...
Read the full Chlorophyllin monograph → Herb & supplement monographPanax Ginseng
Interacts with 1,130 drugsPanax ginseng is a popular traditional herb used to boost energy, ease stress, and support overall wellness, though scientific evidence is mixed and mostly preliminary. It is generally well...
Read the full Panax Ginseng monograph →Sources & How We Checked
Ginseng Immune Health's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 72 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Chlorophyllin 6 references
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- Mathews-Roth MM. Carotenoids in erythropoietic protoporphyria and other photosensitivity diseases. Ann N Y Acad Sci, 1993; 691:127-38. PubMed
- Belen'kii, G. B. and Krikun, B. L. [Treatment of herpes simplex and herpes zoster by chlorophyll preparations]. Sov.Med. 1971;34(1):151-152.
- Rossi E, Borchard K, Cole JM. Pseudoporphyria following self-medication with chlorophyll. Australas J Dermatol. 2015 Feb;56(1):47-8. PubMed
- Zhao CY, Frew JW, Muhaidat J, et al. Chlorophyll-induced pseudoporphyria with ongoing photosensitivity after cessation - a case series of four patients. J Eur Acad Dermatol Venereol 2016;30(7):1239-42. PubMed
- Tomankova K, Kejlova K, Binder S, et al. In vitro cytotoxicity and phototoxicity study of cosmetics colorants. Toxicol In Vitro. 2011 Sep;25(6):1242-50. PubMed
Panax Ginseng 66 references
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC