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Dietary supplement

Glandular System Formula Ingredients & Drug Interactions

by Christopher's Original Formulas

Glandular System Formula label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Glandular System Formula against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Glandular System Formula is a dietary supplement by Christopher's Original Formulas with 2 active ingredients. Its ingredients are commonly taken for cough and chest congestion, sore throat, bronchitis and respiratory irritation.Based on those ingredients, 123 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Mullein, Lobelia. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Glandular System Formula by Christopher's Original Formulas

Ask about any prescription or over-the-counter medication and we check it for interactions with Glandular System Formula by Christopher's Original Formulas — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Glandular System Formula by Christopher's Original Formulas

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (750 mg) without saying how much of each component you get.

This formula contains 2 active ingredients: mullein and lobelia, delivered in a plant-derived capsule. Mullein is a traditional respiratory herb, and lobelia has been historically used for smoking cessation, though we hold limited evidence data for both.

The two active ingredients are blended together in this product.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The label doesn't state a purpose we can grade — see each ingredient's own graded uses on its monograph instead.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence on mullein for bronchitis, asthma, cough, migraine, and diarrhea is insufficient to rate — we don't have enough reliable data to say whether it works for these uses. Lobelia is rated possibly ineffective for smoking cessation based on the data we hold.

In short, the evidence we have on this formula's active ingredients doesn't establish their effectiveness for their traditional purposes.

The evidence, ingredient by ingredient Mullein Lobelia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Mullein is generally well tolerated for short-term use, but human safety data are limited. It can occasionally cause dermatitis with skin contact or inhalation of plant dust.

Lobelia, on the other hand, carries real toxicity risk: it can cause nausea, vomiting, diarrhea, dizziness, tremors, and throat irritation at doses as low as 50 mg, and at 600 mg or higher, it can trigger serious effects including rapid heartbeat, low blood pressure, convulsions, and potentially fatal outcomes. For this reason, caution is strongly advised with lobelia.

The safety data advises against mullein during pregnancy and while breastfeeding — there isn't enough information to know it's safe. Lobelia is rated likely unsafe in pregnancy and while breastfeeding due to toxicity concerns and lack of safety data.

Talk with your doctor or pharmacist before using this product if you're pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient Mullein Lobelia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Lobelia, Mullein.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; lithium.
  • For scale: 123 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start this formula, check your current medications against the following: if you take lithium (a mood stabilizer), lobelia may raise its levels and you may need a dose adjustment — this is a Moderate concern. If you take blood thinners or antiplatelet drugs like warfarin or aspirin, mullein's mild blood-thinning effects could add to theirs, though the risk is Minor.

Run your full medication list through the search tool on this page to confirm.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you take lithium or blood thinners, check with your doctor or pharmacist before starting this product — the interactions may require dose adjustments. Lobelia's toxicity risk at higher doses and limited safety data in pregnancy and breastfeeding also warrant a conversation with your healthcare provider before use.

The evidence on effectiveness for the traditional uses of these herbs is not established in our data.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 24, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Glandular System Formula, straight from the product label.

Brand Christopher's Original Formulas
Barcode (UPC) 084783891123
Net contents 100 Vegetarian Cap(s)
Market status On market
Date entered into DSLD Sep 24, 2019
DSLD ID 200288
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Glandular System Formula by Christopher's Original Formulas, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
50
UPC/BARCODE
084783891123
IngredientAmount% DV
Proprietary Blend750 mg--
Mullein0 NP--
Lobelia0 NP--

Other ingredients: plant-derived Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 2 capsules twice daily, or as directed by your health care professional.

Storage

Store in a cool, dry place.

Precautions

Warning: Do not use during pregnancy, or while nursing, except as directed by our health care professional.

Brand IP Statement(s)

2010 Wholistic Botanicals L.L.C. All Rights Reserved

John R. Christopher

FDA Statement of Identity

Dietary Supplement

General Statements

375 mg each

Formulation

No added fillers or chemicals

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Glandular System Formula by Christopher's Original Formulas label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Glandular System Formula label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Glandular System Formula by Christopher's Original Formulas

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container50 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

750 mg per serving

Other (inactive) ingredients: Plant-derived Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Glandular System Formula by Christopher's Original Formulas Drug Interactions

Want to check YOUR meds against Glandular System Formula?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
123Drugs
1 Moderate 122 Minor

Ingredients driving the most interactions

Mullein 122
Lobelia 1

Individual Drug Interactions

The ingredients in Glandular System Formula interact with 123 drugs. Click any drug to see the details.

2 of the 2 ingredients in Glandular System Formula interact with drugs. Each result below shows which ingredient is responsible. Mullein Lobelia

Each ingredient & the kinds of drugs it affects

For each ingredient in Glandular System Formula with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Mullein1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Lab tests on extracts from different parts of common and dense-flowered mullein plants show that they do have some blood-thinning effects, as they increase the time it takes for blood to clot. This is likely due to at least one of the known constituents of muellein, triterpenoid saponins. However, the effects appear to be mild and results have been inconsistent. Extracts from different plant parts have been show to have varying anticoagulant strengths, with water-based ones being more potent than alcohol-based extracts.

Likelihood Unlikely Evidence A
Mullein full monograph & interactions

Lobelia1 drug type · 1 drug

Lithium

Lobelia is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, lobelia might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Lobelia full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Glandular System Formula, from the product label.

Christopher's Original Formulas

See all Christopher's Original Formulas products
Name
Wholistic Botanicals L.L.C.
City
Spanish Fork
State
UT
ZipCode
84660
Phone Number
1-800-453-1406
Web Address
www.drchristopher.com
Pharmacist Counseling Corner

Glandular System Formula by Christopher's Original Formulas: Common Questions

Does Glandular System Formula by Christopher's Original Formulas interact with any medications?
Yes. Based on its ingredients, Glandular System Formula has a known interaction with 123 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Glandular System Formula contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety data advises against both mullein and lobelia during pregnancy and breastfeeding. There isn't enough information to know mullein is safe, and lobelia is rated likely unsafe due to toxicity concerns. Talk with your doctor or pharmacist before using this product if you're pregnant, planning pregnancy, or nursing.
What is mullein used for in this formula?
Mullein is a traditional respiratory herb used for bronchitis, asthma, cough, and other conditions. However, we don't have enough reliable evidence to say whether it actually works for these purposes.
What is lobelia used for in this formula?
Lobelia has been used historically for smoking cessation. The evidence we hold rates it as possibly ineffective for that use, so it's not proven to help people quit smoking.
Can lobelia cause side effects?
Yes — lobelia can cause nausea, vomiting, diarrhea, dizziness, tremors, and throat irritation at doses as low as 50 mg. At doses of 600 mg or higher, it can trigger toxicity with serious symptoms including rapid heartbeat, low blood pressure, convulsions, and potentially death. Caution is strongly advised.
Is this formula safe to use long-term?
Mullein is generally well tolerated for short-term use, but human safety data are limited — we don't have enough information about long-term safety. Lobelia carries toxicity risk, and caution is strongly advised. Talk with your doctor or pharmacist about how long it's appropriate for you to take this product.
What's in the capsule itself?
The capsule is plant-derived. There are no other inactive fillers or binders listed in the product facts.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Glandular System Formula label
Go deeper

The Full Monographs Behind Glandular System Formula’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Mullein

Interacts with 122 drugs

Mullein is a traditional herbal remedy most often used as a tea or syrup to soothe coughs, sore throats, and respiratory irritation. High-quality human studies are lacking, so its benefits a...

Read the full Mullein monograph → Herb & supplement monograph

Lobelia

Interacts with 1 drug

Lobelia is a traditional herb once used for breathing problems and to help people quit smoking, but reliable evidence supporting these uses is lacking. It can be toxic in higher amounts, cau...

Read the full Lobelia monograph →
Sources

Sources & How We Checked

Glandular System Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Mullein 2 references
  1. Castro AI, Carmona JB, Gonzales FG, Nestar OB. Occupational airborne dermatitis from gordolobo (Verbascum densiflorum). Contact Dermatitis 2006;55(5):301.
  2. Flores Echaiz C, Al Ali A, Cao AQ, Sasseville D. Simultaneous contact dermatitis caused by Asteraceae and Verbascum thapsus. Contact Dermatitis 2017;76(5):316-8.

See these in context on the Mullein monograph →

Lobelia 6 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. McChargue DE, Collins FL Jr, Cohen LM. Effect of non-nicotinic moist snuff replacement and lobeline on withdrawal symptoms during 48-h smokeless tobacco deprivation. Nicotine Tob Res 2002;4:195-200. PubMed
  5. Stead LF, Hughes JR. Lobeline for smoking cessation. Cochrane Database Syst Rev 2000;2:CD000124. PubMed
  6. Plakun, A. L., Ambrus, J., Bross, I., Graham, S., Levin, M. L., and Ross, C. A. Clinical factors in smoking withdrawal: preliminary report. Am J Public Health Nations.Health 1966;56(3):434-441. PubMed

See these in context on the Lobelia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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