No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Glutathione-SR Ingredients & Drug Interactions

by Thorne

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Glutathione-SR is a dietary supplement by Thorne with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, skin lightening or brightening, detoxification support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Glutathione-SR by Thorne

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: glutathione, a compound your body makes naturally and uses to help protect cells from damage. Glutathione-SR is formulated as a sustained-release capsule, designed to release the ingredient gradually.

The inactive ingredients are hydroxypropyl methylcellulose, magnesium citrate, calcium laurate, hypromellose, leucine, and silicon dioxide — standard capsule materials and binders.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Glutathione's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: liver and detoxification support.
  • We looked for evidence on: Cirrhosis, Nonalcoholic fatty liver disease (NAFLD), hepatic function, liver protection.
  • The closest evidence on file: Glutathione is rated "Insufficient Reliable Evidence To Rate" for Cirrhosis (Natural Medicines).
  • Also on file: Glutathione is rated "Insufficient Reliable Evidence To Rate" for Nonalcoholic fatty liver disease (NAFLD).

The evidence for glutathione is mixed. It's possibly effective for reducing nerve damage (neurotoxicity) caused by the chemotherapy drug cisplatin.

For nonalcoholic fatty liver disease, Alzheimer disease, athletic performance, and cataracts, the evidence we have isn't strong enough to say whether it works. More research is needed in those areas.

The evidence, ingredient by ingredient Glutathione

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oral glutathione appears generally well tolerated over the short term, but long-term safety data are limited. If you have asthma, be aware that inhaled (nebulized) glutathione can narrow airways and cause shortness of breath or cough — this product is oral, not inhaled, but it's worth knowing if you've had that reaction before.

During pregnancy, the safety data aren't reliable enough to know either way, so the safety notes advise caution and avoidance unless your doctor advises otherwise. The same applies to breastfeeding — there isn't enough information to know if it's safe, so caution and avoidance are advised.

Side effects, ingredient by ingredient Glutathione

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for glutathione. That said, be sure to run this product through the checker on this page with your complete medication list before you start.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

Glutathione-SR may be worth considering if you're undergoing cisplatin chemotherapy and looking to reduce nerve damage, though talk it over with your oncologist first. If you're pregnant or breastfeeding, the data aren't clear enough to say it's safe — check with your doctor or pharmacist before using it.

And because long-term safety isn't well studied, it's worth a conversation with your own healthcare provider about how long you plan to take it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 21, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Glutathione-SR, straight from the product label.

Brand Thorne
Barcode (UPC) 693749540038
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Feb 21, 2023
DSLD ID 284225
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Glutathione-SR by Thorne, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
693749540038
IngredientAmount% DV
Glutathione175 mg--

Other ingredients: Hydroxypropyl Methylcellulose, Magnesium Citrate, Calcium Laurate, Hypromellose, Leucine, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Liver/Detox Foundational

Sustained release

Gluten free

Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 capsule two to three times daily or as recommended by your health-care practitioner.

Precautions

Tamper evident: Use only if bottle is sealed.

If pregnant, consult your health-care practitioner before using this product.

Storage

Store tightly sealed in a cool, dry place.

Seals/Symbols

NSF Certified sport

FDA Statement of Identity

Dietary Supplement

Formula

Glutathione complexed with Time-Sorb, a time-release matrix.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Glutathione-SR by Thorne label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Glutathione-SR by Thorne

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Glutathione

No known
interactions
175 mg per serving

Glutathione is a powerful antioxidant your body makes naturally, and many people take it as a supplement hoping for skin, detox, or anti-aging benefit...

Glutathione monograph & interactions

Other (inactive) ingredients: Hydroxypropyl Methylcellulose, Magnesium Citrate, Calcium Laurate, Hypromellose, Leucine, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Glutathione-SR by Thorne Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Glutathione-SR. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Glutathione-SR, from the product label.

Thorne

See all Thorne products
Name
Thorne Research, Inc.
Phone Number
1-800-228-1966
Pharmacist Counseling Corner

Glutathione-SR by Thorne: Common Questions

Does Glutathione-SR by Thorne interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Glutathione-SR. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Glutathione-SR contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety data for glutathione during pregnancy and breastfeeding aren't reliable enough to know either way. The safety notes advise caution and avoidance unless your doctor advises otherwise. Talk with your doctor or pharmacist before taking it.
Does this actually work?
Glutathione is possibly effective at reducing nerve damage from cisplatin chemotherapy. For other uses listed — like fatty liver disease, Alzheimer disease, athletic performance, and cataracts — we don't have strong evidence yet that it works.
I have asthma. Is this safe for me?
This is an oral capsule, so it shouldn't cause the airway narrowing that inhaled glutathione can trigger. But if you've had breathing problems with nebulized glutathione before, mention this product to your doctor to be safe.
How long can I take this safely?
Oral glutathione appears well tolerated over the short term, but long-term safety data are limited. It's worth discussing with your doctor or pharmacist how long you plan to take it and whether they think that's appropriate for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Glutathione-SR is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Glutathione-SR label
Go deeper

The Full Monographs Behind Glutathione-SR’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Glutathione-SR's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutathione 1 reference
  1. Marrades RM, Roca J, Barbera JA, et al. Nebulized glutathione induces bronchoconstriction in patients with mild asthma. Am J Respir Crit Care Med 1997;156(2 Pt 1):425-30. PubMed

See these in context on the Glutathione monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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