No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Gluten/Dairy Digest Ingredients & Drug Interactions

by Pure Encapsulations

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Gluten/Dairy Digest is a dietary supplement by Pure Encapsulations with 3 active ingredients. Its ingredients are commonly taken for lactose intolerance, gas and bloating after dairy, diarrhea from dairy foods.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Gluten/Dairy Digest by Pure Encapsulations

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “BioCore Dairy” is listed as a grouped ingredient — the label gives one combined amount (105 mg) without saying how much of each component you get.

This product has three active ingredients designed to help break down lactose and dairy proteins. Lactase is an enzyme that splits lactose (milk sugar) so your body can absorb it more easily.

Protease is a protein-digesting enzyme. The product also includes Tolerase G, a proprietary blend we can't fully detail here, plus two inactive ingredients: cellulose and water.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: supports gluten and dairy digestion.
  • We looked for evidence on: Lactose intolerance, Dairy sensitivity, Gluten sensitivity, Digestive discomfort.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).

Lactase is effective for lactose intolerance — that's solid evidence. The data on lactase for prematurity and colic doesn't yet support a clear rating.

Protease's effectiveness isn't established in the data we hold. If you're adding this to handle dairy digestion, lactase is the ingredient with the strongest track record.

The evidence, ingredient by ingredient Lactase Proteolytic Enzymes (proteases)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactase is generally well tolerated when used as directed. A rare case of allergic contact dermatitis and allergic rhinoconjunctivitis from occupational exposure to powdered lactase has been reported, though that's a workplace inhalation scenario, not typical oral use.

Protease is generally well tolerated for most adults but may cause digestive upset or allergic reactions in some people. Because protease safety hasn't been fully established in pregnancy, it's best avoided during pregnancy unless your doctor says otherwise.

During breastfeeding, there's little safety data, so talk with your doctor or pharmacist before use. Lactase is rated likely safe in pregnancy and lactation.

We don't have pregnancy or breastfeeding safety data on file for Tolerase G.

Side effects, ingredient by ingredient Lactase Proteolytic Enzymes (proteases)

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 2 matched ingredients has a documented medication interaction on file.

No interactions are documented for the ingredients we could check. That said, always confirm with your own doctor or pharmacist that this product won't interfere with anything you're taking — we hold no data on Tolerase G's components.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This product is a reasonable choice if you struggle with dairy digestion and want to try a digestive enzyme blend. If you're pregnant, breastfeeding, or take any regular medications, talk it over with your doctor or pharmacist first — especially to confirm protease is okay for your situation.

Run your specific medications through the checker on this page before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Gluten/Dairy Digest, straight from the product label.

Brand Pure Encapsulations
Barcode (UPC) 766298024158
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Nov 22, 2023
DSLD ID 299053
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Gluten/Dairy Digest by Pure Encapsulations, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
766298024158
IngredientAmount% DV
Lactase0 NP--
Tolerase G0 NP--
Protease0 NP--
BioCore Dairy105 mg--

Other ingredients: Cellulose, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage

Store in a cool, dry place.

Suggested/Recommended/Usage/Directions

Recommendations: As a dietary supplement, take 1 capsule as needed, with a meal, or as directed by a health care professional.

Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

Precautions

Keep out of the reach of children.

Use only if safety seal is intact.

General Statements

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our hypoallergenic supplements

Seals/Symbols

GFCO.org (Gluten-Free Certification Organization) Certified Gluten-Free by the Gluten-Free Certified Organization, www.gluten.org

Formulation

GFCO.org (Gluten-Free Certification Organization) Certified Gluten-Free by the Gluten-Free Certified Organization, www.gluten.org

Supports gluten and dairy digestion Gluten-free, Non-GMO & Hypoallergenic

Gluten-free, Non-GMO & Hypoallergenic

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

BioCore is a trademark of National Enzyme Company. Tolerase G is a trademark of DSM. Tolerase G is not intended to replace a gluten-free diet. Tolerase G is not intended to treat or prevent celiac disease.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Gluten/Dairy Digest by Pure Encapsulations label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Gluten/Dairy Digest by Pure Encapsulations

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Tolerase G

0 NP per serving Form: Prolyl Endopeptidase

BioCore Dairy

105 mg per serving

Other (inactive) ingredients: Cellulose, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Gluten/Dairy Digest by Pure Encapsulations Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Gluten/Dairy Digest. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Gluten/Dairy Digest, from the product label.

Pure Encapsulations

See all Pure Encapsulations products
Name
Pure Encapsulations
Street Address
490 Boston Post Road
City
Sudbury
State
MA
Phone Number
1-800-753-2277
Web Address
www.PureEncapsulations.com
Pharmacist Counseling Corner

Gluten/Dairy Digest by Pure Encapsulations: Common Questions

Does Gluten/Dairy Digest by Pure Encapsulations interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Gluten/Dairy Digest. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Gluten/Dairy Digest contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is lactase safe if I'm pregnant?
Lactase is rated likely safe in pregnancy. That said, the data suggests you check with your doctor before regular use, just to be sure it's the right choice for you personally.
Can I use this if I'm breastfeeding?
Lactase is rated likely safe during breastfeeding. Protease, however, has limited breastfeeding safety data, so ask your doctor or pharmacist first before using this product while nursing.
What does lactase actually do?
Lactase is an enzyme that breaks down lactose — the sugar in milk and dairy products — so your body can digest and absorb it. If you're lactose intolerant, lactase helps prevent bloating, gas, and stomach upset after eating dairy.
Is protease safe to use regularly?
Protease is generally well tolerated for most adults, but it may cause digestive upset or allergic reactions in some people. If you plan to use this regularly, talk with your doctor or pharmacist to make sure it's safe for you.
Could I be allergic to this product?
Yes. Rare allergic reactions to lactase and protease have been reported, typically from occupational exposure to the powdered forms, but allergic reactions are possible. If you notice any allergic symptoms like rash, swelling, or trouble breathing, stop and seek medical help right away.
What's Tolerase G?
Tolerase G is a proprietary blend ingredient in this product — we don't hold detailed data on its exact components, so we can't fully assess it. If you have questions about what's in it, reach out to Pure Encapsulations directly.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Gluten/Dairy Digest is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Gluten/Dairy Digest label
Sources

Sources & How We Checked

Gluten/Dairy Digest's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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