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Dietary supplement

Glycine 3000 mg Capsules Ingredients & Drug Interactions

by BulkSupplements.com

Capsule Category: Amino Acid/protein
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Glycine 3000 mg Capsules is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for sleep quality and insomnia, relaxation, cognitive function.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Glycine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Glycine 3000 mg Capsules by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: glycine, an amino acid your body makes naturally and uses in protein synthesis and nervous system function. Each capsule delivers 3,000 mg.

The capsule itself is made from bovine gelatin, an inactive ingredient that holds the glycine together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Glycine's overall clinical evidence instead.

Moderate

Some clinical evidence supports Glycine for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Schizophrenia — rated "Possibly Effective" (Natural Medicines).

Glycine is possibly effective for schizophrenia based on the evidence we have on file. For other uses listed—including 3-phosphoglycerate dehydrogenase (3-PGDH) deficiency, attention deficit-hyperactivity disorder (ADHD), benign prostatic hyperplasia (enlarged prostate, or BPH), and cystic fibrosis—there isn't enough reliable evidence yet to say whether it works.

The evidence, ingredient by ingredient Glycine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Glycine is generally well tolerated at typical doses, though long-term safety data are limited. Mild sedation has occurred rarely and resolves quickly if you stop taking it.

A small number of users have reported irritability, insomnia, fatigue, memory issues, headache, and sensory changes, though it's unclear whether glycine caused them. Rarely, some people experience soft stools, nausea, vomiting, stomach discomfort, or dry mouth—these also resolve quickly with discontinuation.

There isn't enough reliable safety data to know whether glycine is safe during pregnancy or while breastfeeding. Talk with your doctor or pharmacist before use if you're pregnant, planning to become pregnant, or nursing.

Side effects, ingredient by ingredient Glycine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glycine.
  • The most serious interaction on file is rated Moderate.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist or doctor before taking this if you're on clozapine (Clozaril). Glycine may decrease how well this antipsychotic works and could worsen schizophrenia symptoms.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Glycine may help with schizophrenia if your doctor approves it. If you take clozapine, don't start this product without checking first—the two together may work against each other.

For other uses, the evidence isn't established yet. Chat with your pharmacist before you begin, especially if you're pregnant, breastfeeding, or on any medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 23, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Glycine 3000 mg Capsules, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X003K52UTH
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD May 23, 2024
DSLD ID 312898
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Glycine 3000 mg Capsules by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
33
UPC/BARCODE
X003K52UTH
IngredientAmount% DV
Glycine3000 mg--

Other ingredients: Bovine Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Glycine 3000 mg per serving

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 3 capsules once daily, or as directed by a physician.

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

Storage

Store in a dry, cool place

General Statements

New

Scan me

Formulation

Free of: Added sugar, dairy, yeast, soy, gluten, additives

See for yourself

Glycine 3000 mg Capsules by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Glycine 3000 mg Capsules by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container33 Amounts shown are per serving.

Glycine

Interacts with
1 drug
3000 mg per serving

Glycine is a non-essential amino acid your body makes on its own and that also appears in protein-rich foods. It is most studied for improving sleep q...

Glycine monograph & interactions

Other (inactive) ingredients: Bovine Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Glycine 3000 mg Capsules by BulkSupplements.com Drug Interactions

Want to check YOUR meds against Glycine 3000 mg Capsules?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Glycine 3000 mg Capsules with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Glycine1 drug type · 1 drug

Clozapine (Clozaril)

Theoretically, glycine might decrease the effectiveness of clozapine.
One small clinical study in patients with schizophrenia shows that adding glycine to clozapine therapy worsens symptoms of schizophrenia when compared with clozapine alone. The mechanism of this interaction is unclear.

Likelihood Probable Evidence B
The maker

Brand information

Manufacturer and brand details for Glycine 3000 mg Capsules, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

Glycine 3000 mg Capsules by BulkSupplements.com: Common Questions

Does Glycine 3000 mg Capsules by BulkSupplements.com interact with any medications?
Yes. Based on its ingredients, Glycine 3000 mg Capsules has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Glycine 3000 mg Capsules contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is glycine, and what does it do in my body?
Glycine is an amino acid your body naturally produces and uses to build proteins and support your nervous system. This supplement provides extra glycine in case your diet or your body's own production falls short.
Can I take this if I'm pregnant or breastfeeding?
The safety data for glycine during pregnancy and breastfeeding aren't complete enough to know either way. Talk with your doctor or pharmacist before you start—they can give you personalized advice based on your situation.
Is glycine safe to take long-term?
Glycine is generally well tolerated at typical doses, but we don't have enough long-term safety data to say for certain how safe it is over years of use. If you're planning to take it regularly, it's worth checking in with your pharmacist.
What side effects might I notice?
Most people don't experience problems, but mild sedation, stomach upset (soft stools, nausea, vomiting), or dry mouth have occurred rarely and resolve quickly if you stop. Some people have reported irritability, insomnia, or headache, though it's unclear if glycine caused them.
Does this product have any fillers or inactive ingredients?
The capsule is made from bovine gelatin. If you have a beef allergy or follow a vegetarian diet, let your pharmacist know so we can help you find an alternative.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Glycine 3000 mg Capsules is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Glycine 3000 mg Capsules label
Go deeper

The Full Monographs Behind Glycine 3000 mg Capsules’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Glycine 3000 mg Capsules's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glycine 5 references
  1. Heresco-Levy U, Javitt DC, Ermilov M, et al. Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia. Arch Gen Psychiatry 1999;56:29-36.. PubMed
  2. Potkin SG, Jin Y, Bunney BG, Costa J, Gulasekaram B. Effect of clozapine and adjunctive high-dose glycine in treatment-resistant schizophrenia. Am J Psychiatry 1999;156:145-7.. PubMed
  3. Gusev EI, Skvortsova VI, Dambinova SA, et al. Neuroprotective effects of glycine for therapy of acute ischaemic stroke. Cerebrovasc Dis 2000;10:49-60. PubMed
  4. Inagawa K, Kawai N, Ono K, Sukegawa E, Tsubuku S, Takahashi M. Assessment of acute adverse effects of glycine ingestion at a high dose in human volunteers. Seikatsu Eisei. 2006; 50:27-32.
  5. Woods SW, Walsh BC, Hawkins KA, Miller TJ, Saksa JR, D'Souza DC, Pearlson GD, Javitt DC, McGlashan TH, Krystal JH. Glycine treatment of the risk syndrome for psychosis: report of two pilot studies. Eur Neuropsychopharmacol. 2013 Aug;23(8):931-40. PubMed

See these in context on the Glycine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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