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Dietary supplement

Glycine Powder 3000 mg Ingredients & Drug Interactions

by BulkSupplements.com

Glycine Powder 3000 mg label
See full label image
Powder Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Glycine Powder 3000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Glycine Powder 3000 mg is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for sleep quality and insomnia, relaxation, cognitive function.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Glycine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Glycine Powder 3000 mg by BulkSupplements.com

Ask about any prescription or over-the-counter medication and we check it for interactions with Glycine Powder 3000 mg by BulkSupplements.com — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Glycine Powder 3000 mg by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: glycine, an amino acid your body makes naturally and also gets from protein-rich foods. The powder form delivers 3,000 mg per serving.

There are no inactive ingredients listed.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Glycine's overall clinical evidence instead.

Moderate

Some clinical evidence supports Glycine for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Schizophrenia — rated "Possibly Effective" (Natural Medicines).

Glycine is possibly effective for schizophrenia based on available evidence. However, the research also shows that adding it to clozapine therapy may actually worsen symptoms, so effectiveness in that specific setting is complicated.

For other conditions — including a rare enzyme deficiency called 3-phosphoglycerate dehydrogenase (3-PGDH) deficiency, ADHD, benign prostatic hyperplasia (enlarged prostate), and cystic fibrosis — there isn't enough reliable evidence yet to rate how well it works.

The evidence, ingredient by ingredient Glycine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Glycine is generally well tolerated at typical doses, though long-term safety data are limited. Rarely, people have reported mild sedation, irritability, insomnia, fatigue, memory problems, headache, sensory changes, soft stools, nausea, vomiting, stomach discomfort, and dry mouth — but these symptoms resolve quickly if you stop taking it.

Some of these side effects may not be directly caused by glycine. There isn't enough reliable safety data during pregnancy, so it's best avoided unless your doctor approves.

The same goes for breastfeeding — caution is advised because we don't have enough data.

Side effects, ingredient by ingredient Glycine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glycine.
  • The most serious interaction on file is rated Moderate.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take clozapine (Clozaril) for schizophrenia, check with your pharmacist or doctor first — glycine may worsen your symptoms with this medication. No other medication interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Glycine powder is generally well tolerated and possibly effective for schizophrenia, but adding it to clozapine therapy has shown to worsen symptoms. If you take clozapine or any other psychiatric medication, talk to your pharmacist or doctor before starting.

Otherwise, this ingredient has limited long-term safety data, so discuss with your healthcare provider whether it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 21, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Glycine Powder 3000 mg, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X000HIGIB1
Net contents 250 Gram(s); 8.8 Ounce(s)
Market status On market
Date entered into DSLD May 21, 2025
DSLD ID 330956
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Glycine Powder 3000 mg by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3000 Milligram(s)
Maximum serving Sizes:
3000 Milligram(s)
Servings per container
83
UPC/BARCODE
X000HIGIB1
IngredientAmount% DV
Glycine3000 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Glycine Powder 3000 mg per serving

Brand IP Statement(s)

Bulksupplements.com Clean & pure bulk supplements

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

Formulation

Free of: Added sugar, soy, dairy, yeast, gluten, additives

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 3000 mg (about 1 1/5 tsp) daily, or as directed by a physician.

General Statements

Use an accurate milligram scale. New

Storage

Contents are sold by weight, not volume. Settling may occur. Store in a dry, cool place

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Glycine Powder 3000 mg by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Glycine Powder 3000 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Glycine Powder 3000 mg by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3000 Milligram(s) Dosage formPowder Servings per container83 Amounts shown are per serving.

Glycine

Interacts with
1 drug
3000 mg per serving

Glycine is a non-essential amino acid your body makes on its own and that also appears in protein-rich foods. It is most studied for improving sleep q...

Glycine monograph & interactions
Interaction report

Glycine Powder 3000 mg by BulkSupplements.com Drug Interactions

Want to check YOUR meds against Glycine Powder 3000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

Glycine 1

Individual Drug Interactions

The ingredients in Glycine Powder 3000 mg interact with 1 drug. Click any drug to see the details.

1 of the 1 ingredient in Glycine Powder 3000 mg interact with drugs. Each result below shows which ingredient is responsible. Glycine

Each ingredient & the kinds of drugs it affects

For each ingredient in Glycine Powder 3000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Glycine1 drug type · 1 drug

Clozapine (Clozaril)

Theoretically, glycine might decrease the effectiveness of clozapine.
One small clinical study in patients with schizophrenia shows that adding glycine to clozapine therapy worsens symptoms of schizophrenia when compared with clozapine alone. The mechanism of this interaction is unclear.

Likelihood Probable Evidence B
Glycine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Glycine Powder 3000 mg, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

Glycine Powder 3000 mg by BulkSupplements.com: Common Questions

Does Glycine Powder 3000 mg by BulkSupplements.com interact with any medications?
Yes. Based on its ingredients, Glycine Powder 3000 mg has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Glycine Powder 3000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is glycine safe to use during pregnancy or while breastfeeding?
There isn't enough reliable safety data to know either way for pregnancy or breastfeeding. Talk with your doctor or pharmacist before using it if you're pregnant, planning to become pregnant, or breastfeeding — they can give you personalized advice based on your situation.
What are the side effects of glycine?
Most people tolerate it well, but rare side effects include mild sedation, irritability, insomnia, fatigue, memory problems, headache, nausea, vomiting, soft stools, and dry mouth. These symptoms resolve quickly if you stop taking it. Some reported effects may not be directly caused by glycine.
Does glycine work for schizophrenia?
It's possibly effective for schizophrenia based on available evidence. However, if you're already taking clozapine (a common schizophrenia medication), adding glycine may actually make your symptoms worse — so don't add this without talking to your doctor first.
Can I use glycine for ADHD, BPH, or cystic fibrosis?
There isn't enough reliable evidence yet to say whether glycine works for ADHD, benign prostatic hyperplasia (enlarged prostate), or cystic fibrosis. Your doctor can tell you if it might help in your specific case.
What's the long-term safety profile of glycine?
Glycine is generally well tolerated at typical doses, but long-term safety data are limited. If you plan to use it regularly for a long time, discuss that with your pharmacist or doctor.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Glycine Powder 3000 mg label
Go deeper

The Full Monographs Behind Glycine Powder 3000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glycine

Interacts with 1 drug

Glycine is a non-essential amino acid your body makes on its own and that also appears in protein-rich foods. It is most studied for improving sleep quality, where early research is promisin...

Read the full Glycine monograph →
Sources

Sources & How We Checked

Glycine Powder 3000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glycine 5 references
  1. Heresco-Levy U, Javitt DC, Ermilov M, et al. Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia. Arch Gen Psychiatry 1999;56:29-36.. PubMed
  2. Potkin SG, Jin Y, Bunney BG, Costa J, Gulasekaram B. Effect of clozapine and adjunctive high-dose glycine in treatment-resistant schizophrenia. Am J Psychiatry 1999;156:145-7.. PubMed
  3. Gusev EI, Skvortsova VI, Dambinova SA, et al. Neuroprotective effects of glycine for therapy of acute ischaemic stroke. Cerebrovasc Dis 2000;10:49-60. PubMed
  4. Inagawa K, Kawai N, Ono K, Sukegawa E, Tsubuku S, Takahashi M. Assessment of acute adverse effects of glycine ingestion at a high dose in human volunteers. Seikatsu Eisei. 2006; 50:27-32.
  5. Woods SW, Walsh BC, Hawkins KA, Miller TJ, Saksa JR, D'Souza DC, Pearlson GD, Javitt DC, McGlashan TH, Krystal JH. Glycine treatment of the risk syndrome for psychosis: report of two pilot studies. Eur Neuropsychopharmacol. 2013 Aug;23(8):931-40. PubMed

See these in context on the Glycine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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