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Dietary supplement

Pomegranate Extract 40% Ellagic Acid Ingredients & Drug Interactions

by BulkSupplements.com

Powder Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Pomegranate Extract 40% Ellagic Acid is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, general anti-aging or 'cleanse' products, cancer prevention interest.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Ellagic Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Pomegranate Extract 40% Ellagic Acid by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: ellagic acid, a compound from pomegranate. The powder is delivered as a concentrated extract standardized to 40% ellagic acid by weight.

No inactive ingredients are present.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Ellagic Acid product and its label doesn't state a use — see Ellagic Acid's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for ellagic acid is not yet established in the data we hold. It's been studied for bladder cancer, prostate cancer, brain function, type 2 diabetes, melasma (a skin discoloration condition), and polycystic ovary syndrome — but all those uses are rated insufficient reliable evidence.

That means the research so far doesn't support a clear claim that it works for any of them.

The evidence, ingredient by ingredient Ellagic Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Ellagic acid is generally considered safe when you get it from food, but concentrated supplements haven't been well studied in humans. The safety notes advise caution with supplement doses — food amounts are fine, but concentrated supplements are best avoided until we know more.

In one clinical trial, a combination product containing ellagic acid and graviola was linked to nausea and diarrhea in a small number of participants, though it's unclear whether ellagic acid alone was responsible.

Side effects, ingredient by ingredient Ellagic Acid

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Ellagic Acid.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs like metformin or other medications to control blood sugar, check with your doctor or pharmacist before starting this product — ellagic acid may increase the risk of low blood sugar (hypoglycemia), which is a Moderate concern.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is one to run by your doctor or pharmacist before you take it, especially if you're on antidiabetes medication — ellagic acid may lower blood sugar. The concentrated form hasn't been well studied in humans, so talk it over with your own healthcare provider about whether it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 24, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pomegranate Extract 40% Ellagic Acid, straight from the product label.

Brand BulkSupplements.com
Net contents 100 Gram(s); 3.53 Ounce(s)
Market status On market
Date entered into DSLD Sep 24, 2021
DSLD ID 254236
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pomegranate Extract 40% Ellagic Acid by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
750 mg
Maximum serving Sizes:
750 mg
Servings per container
133
IngredientAmount% DV
Ellagic Acid300 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Clean & Pure Bulk Supplements

US Standard Measuring Spoons Spoon size (level) milligrams 1/8 teaspoon 391 1/4 teaspoon 782 1/2 teaspoon 1564

Precautions

Warning: This product is not intended for use by those with a serious medical condition or pregnant or lactating women. Consult your physician before use.

Keep out of reach of children!

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Free of: Sugar, soy, dairy, yeast, gluten, or additives

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 750 mg (scant 1/4 tsp) twice daily, or as directed by a physician.

Storage

Storage: keep dry, cool & dark

See for yourself

Pomegranate Extract 40% Ellagic Acid by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pomegranate Extract 40% Ellagic Acid by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size750 mg Dosage formPowder Servings per container133 Amounts shown are per serving.

Ellagic Acid

Interacts with
86 drugs
300 mg per serving

Ellagic acid is a natural plant compound (a polyphenol) found in foods like pomegranates, raspberries, strawberries, and walnuts. It is studied mostly...

Ellagic Acid monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pomegranate Extract 40% Ellagic Acid by BulkSupplements.com Drug Interactions

Want to check YOUR meds against Pomegranate Extract 40% Ellagic Acid?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Pomegranate Extract 40% Ellagic Acid with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Ellagic Acid1 drug type · 86 drugs

Antidiabetes Drugs

Some clinical research shows that ellagic acid reduces fasting and postprandial glucose levels in patients with type 2 diabetes who are on stable doses of hypoglycemic agents such as metformin. Theoretically, taking ellagic acid with antidiabetes drugs might increase the risk of hypoglycemia.

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for Pomegranate Extract 40% Ellagic Acid, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Road
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

Pomegranate Extract 40% Ellagic Acid by BulkSupplements.com: Common Questions

Does Pomegranate Extract 40% Ellagic Acid by BulkSupplements.com interact with any medications?
Yes. Based on its ingredients, Pomegranate Extract 40% Ellagic Acid has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pomegranate Extract 40% Ellagic Acid contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this work for blood sugar or diabetes?
The evidence isn't established yet. Ellagic acid has been studied for type 2 diabetes, but the research so far is rated insufficient — we can't say it works based on what we know.
Can I take this if I'm on diabetes medication?
That's a conversation for your doctor or pharmacist. Research suggests ellagic acid may lower blood sugar, which raises the risk of low blood sugar if you're already on diabetes drugs — you may need monitoring or a dose adjustment.
What are the side effects?
In one trial, a product combining ellagic acid with another herb caused nausea and diarrhea in a small number of people, though it's not clear whether ellagic acid alone was the cause. Concentrated ellagic acid supplements aren't well studied in humans overall.
Is this safe to take long-term?
Ellagic acid from food is considered safe, but concentrated supplement doses haven't been well studied in humans — so we don't have the data to say one way or the other. Talk with your doctor or pharmacist if you're thinking about taking it regularly.
Is it safe during pregnancy or breastfeeding?
There isn't enough safety information on file for ellagic acid during pregnancy or lactation — we can't say either way. Discuss this with your doctor or pharmacist for personalized advice.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pomegranate Extract 40% Ellagic Acid is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pomegranate Extract 40% Ellagic Acid label
Go deeper

The Full Monographs Behind Pomegranate Extract 40% Ellagic Acid’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Pomegranate Extract 40% Ellagic Acid's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 9 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ellagic Acid 9 references
  1. Ertam I, Mutlu B, Unal I, Alper S, Kivçak B, Ozer O. Efficiency of ellagic acid and arbutin in melasma: a randomized, prospective, open-label study. J Dermatol. 2008;35(9):570-4. PubMed
  2. Dahl A, Yatskayer M, Raab S, Oresajo C. Tolerance and efficacy of a product containing ellagic and salicylic acids in reducing hyperpigmentation and dark spots in comparison with 4% hydroquinone. J Drugs Dermatol. 2013;12(1):52-8.
  3. Falsaperla M, Morgia G, Tartarone A, Ardito R, Romano G. Support ellagic acid therapy in patients with hormone refractory prostate cancer (HRPC) on standard chemotherapy using vinorelbine and estramustine phosphate. Eur Urol. 2005;47(4):449-54 PubMed
  4. Le Donne M, Lentini M, Alibrandi A, et al. Antiviral activity of Ellagic acid and Annona Muricata in cervical HPV related pre-neoplastic lesions: A randomized trial. J Funct Food 2017;35:549-54. DOI
  5. Liu Y, Yu S, Wang F, et al. Chronic administration of ellagic acid improved the cognition in middle-aged overweight men. Appl Physiol Nutr Metab. 2018;43(3):266-73. PubMed
  6. Serretta V, Berardinis E, Simonato A, et al. A prospective observational study on oral administration of Ellagic Acid and Annona Muricata in patients affected by non-muscle invasive bladder cancer not undergoing maintenance after 6-week intravesical proph
  7. Ghadimi M, Foroughi F, Hashemipour S, et al. Randomized double-blind clinical trial examining the Ellagic acid effects on glycemic status, insulin resistance, antioxidant, and inflammatory factors in patients with type 2 diabetes. Phytother Res 2021;35(2) PubMed
  8. Kazemi M, Lalooha F, Nooshabadi MR, Dashti F, Kavianpour M, Haghighian HK. Randomized double blind clinical trial evaluating the Ellagic acid effects on insulin resistance, oxidative stress and sex hormones levels in women with polycystic ovarian syndrome PubMed
  9. Ghadimi M, Foroughi F, Hashemipour S, et al. Decreased insulin resistance in diabetic patients by influencing Sirtuin1 and Fetuin-A following supplementation with ellagic acid: a randomized controlled trial. Diabetol Metab Syndr 2021;13(1):16. PubMed

See these in context on the Ellagic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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