Guanabana Graviola Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Guanabana Graviola against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Guanabana Graviola is a dietary supplement by Sunshine Naturals with 1 active ingredient. Its ingredients are commonly taken for cancer support (unproven), infections, inflammation.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Graviola. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Guanabana Graviola by Sunshine Naturals
Ask about any prescription or over-the-counter medication and we check it for interactions with Guanabana Graviola by Sunshine Naturals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Guanabana Graviola by Sunshine Naturals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: graviola, a fruit extract from a tropical tree. The capsule also contains magnesium stearate as an inactive ingredient (a binder).
Does it work?
Couldn't assess
The evidence we hold for graviola doesn't establish that it works for any condition. Studies would be needed to rate its effectiveness for human papillomavirus (HPV), headache, insect repellent use, or male infertility — all of which currently have insufficient reliable evidence.
How safe is it?
Well-documented data
Regular use of graviola raises safety concerns. The most common side effects from oral use are stomach pain and nausea, reported in clinical trials at doses of 300 mg daily.
Rare but serious risks include movement disorders and nerve damage (myeloneuropathy) that can resemble Parkinson disease symptoms. Long-term use carries theoretical concerns about nerve toxicity based on lab studies.
Graviola should not be used during pregnancy or while breastfeeding — safety data are too limited, and traditional use has avoided it in both situations.
Meds to double-check
Moderate interaction found
If you take carbamazepine (Tegretol) or any other seizure medication, check with your pharmacist before starting—graviola may reduce how well it works. For any other prescription drugs, use the interaction search tool on this page to be sure.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Graviola's effectiveness for any health condition isn't established in our data, and regular use carries documented safety concerns including stomach upset and rare neurological risks. If you're taking carbamazepine or any other seizure medication, don't start this product without checking with your pharmacist.
Talk with us before adding it to your routine.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Guanabana Graviola, straight from the product label.
| Brand | Sunshine Naturals |
|---|---|
| Barcode (UPC) | 789939101520 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Aug 23, 2022 |
| DSLD ID | 271249 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Guanabana Graviola by Sunshine Naturals, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: Adults take 2 capsules a day with or before meals.
Formula
Guanabana: Is also known as Graviola or Soursop. The fruit is said to be a natural remedy and also considered a supreme antioxidant.
(Annona Muricata) (Soursop)
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Precautions
Keep out of the reach of children.
Do not use if safety seal is broken or missing.
Storage
Store in a cool dry place.
Formulation
Supreme antioxidant
Proudly Made in the USA.
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
Proudly Made in the USA.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Guanabana Graviola by Sunshine Naturals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Guanabana Graviola by Sunshine Naturals
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Graviola
Interacts with1 drug
Graviola (soursop) is a tropical fruit tree whose leaves, fruit, and bark are used in traditional medicine, especially in parts of South America, Afri...
Graviola monograph & interactionsOther (inactive) ingredients: Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
Guanabana Graviola by Sunshine Naturals Drug Interactions
HelloPharmacist Interaction Report
Guanabana Graviola by Sunshine Naturals interacts with at least one medication we have data for.
Graviola may lower blood levels of carbamazepine (Tegretol), a seizure medication. A rat study found that graviola extract reduced carbamazepine concentrations by roughly one-third to nearly half, which could make the seizure drug less effective at preventing breakthrough seizures.
Read the full breakdown — every affected drug type, severity by severity
Although we've only documented interaction data for carbamazepine, if you take any prescription medications—especially anticonvulsants or any drug your liver metabolizes—it's worth checking them against the interaction search tool below before you start this supplement.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Guanabana Graviola?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Guanabana Graviola interact with 1 drug. Click any drug to see the details.
1 of the 1 ingredient in Guanabana Graviola interact with drugs. Each result below shows which ingredient is responsible. Graviola
CarbamazepineCarbatrol, Carnexiv, Equetro, Tegretol, Tegretol XR
How Carbamazepine interacts with Guanabana Graviola — through 1 ingredient. Tap an ingredient for the detail:
GraviolaCarbamazepine (tegretol) Moderate
Interaction Summary
Theoretically, graviola might decrease concentrations of carbamazepine when used concomitantly.
Read the full Graviola + Carbamazepine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Guanabana Graviola with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Graviola
Carbamazepine (Tegretol)
Theoretically, graviola might decrease concentrations of carbamazepine when used concomitantly.
A study in rats shows that graviola extract reduces the area under the curve of carbamazepine by 46% and maximum concentration by 35% when compared with carbamazepine alone.
Brand information
Manufacturer and brand details for Guanabana Graviola, from the product label.
Sunshine Naturals
See all Sunshine Naturals products- Name
- American Naturavit Inc.
- City
- Miami
- State
- FL
- ZipCode
- 33166
- Phone Number
- 305-593-5417
- Web Address
- www.sunshinenaturals.com
Guanabana Graviola by Sunshine Naturals: Common Questions
Does Guanabana Graviola by Sunshine Naturals interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this during pregnancy?
Is it safe to breastfeed while taking graviola?
What side effects might I experience?
Does graviola actually work for HPV, headaches, or other conditions?
Why does it say graviola might reduce seizure medication levels?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Guanabana Graviola is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Guanabana Graviola’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Guanabana Graviola's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Graviola 4 references
- Caparros-Lefebvre D, Elbaz A. Possible relation of atypical parkinsonism in the French West Indies with consumption of tropical plants: a case-control study. Caribbean Parkinsonism Study Group. Lancet 1999;354:281-6. PubMed
- Gavamukulya Y, Wamunyokoli F, El-Shemy HA. Annona muricata: Is the natural therapy to most disease conditions including cancer growing in our backyard? A systematic review of its research history and future prospects. Asian Pac J Trop Med. 2017;10(9):835- PubMed
- Abu Soukhon AA, Abu-Qatouseh L, Mansoor K, et al. Cytotoxicity Activity of Graviola Fruit Extract with Carbamazepine and Valproic Acid Show Antagonistic and Indifferent Effects. Asian Pac J Cancer Prev 2023;24(6):1869-1875. PubMed
- Cleret de Langavant L, Roze E, Petit A, et al. Annonaceae Consumption Worsens Disease Severity and Cognitive Deficits in Degenerative Parkinsonism. Mov Disord 2022;37(12):2355-2366. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC