Graviola Fruit 450 mg Ingredients & Drug Interactions
by TerraVita Premium Collection
What is this page for?
First and foremost: checking Graviola Fruit 450 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Graviola Fruit 450 mg is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for cancer support (unproven), infections, inflammation.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Graviola. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Graviola Fruit 450 mg by TerraVita Premium Collection
Ask about any prescription or over-the-counter medication and we check it for interactions with Graviola Fruit 450 mg by TerraVita Premium Collection — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Graviola Fruit 450 mg by TerraVita Premium Collection
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: graviola fruit at 450 mg per capsule. Graviola is a tropical fruit traditionally used in herbal medicine.
The capsule itself is made from gelatin and water as inactive ingredients.
Does it work?
Couldn't assess
The evidence we hold on graviola fruit doesn't establish that it works for the conditions it's marketed for. We have insufficient reliable evidence to rate its effectiveness for HPV-related concerns, headache, use as an insect repellent, or male infertility.
If you're considering it for a specific reason, talk with your doctor about whether the evidence supports its use for your situation.
How safe is it?
Well-documented data
Regular use of graviola fruit raises some safety concerns. The most common side effects reported in studies are stomach pain and nausea, especially with daily use.
Rare but serious concerns include movement disorders and nerve damage (myeloneuropathy) that can resemble Parkinson disease symptoms. One observational study found that even small amounts of graviola over time were linked to worsening movement and thinking problems in people with Parkinson disease.
During pregnancy, there isn't enough safety data—the facts recommend avoiding it. The same applies to breastfeeding.
If you're pregnant or nursing and interested in graviola, discuss it with your doctor or midwife first. Long-term use also carries theoretical concerns about nerve toxicity based on lab studies.
Meds to double-check
Moderate interaction found
If you take carbamazepine (Tegretol) for seizures, check with your doctor or pharmacist before using this product—graviola may lower the medication's effectiveness by reducing its blood levels. No other medication interactions are documented for this product in the data we hold.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Graviola fruit is generally well tolerated at short-term doses, but regular use carries real risks of stomach upset and rare but serious nerve and movement problems. If you take carbamazepine (Tegretol) for seizures, you must check with your doctor or pharmacist before starting this product.
It's not recommended during pregnancy or breastfeeding. Talk with your healthcare provider about whether graviola makes sense for you and your health situation.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Graviola Fruit 450 mg, straight from the product label.
| Brand | TerraVita Premium Collection |
|---|---|
| Barcode (UPC) | 064435204723 |
| Net contents | 100 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Mar 22, 2023 |
| DSLD ID | 289038 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Graviola Fruit 450 mg by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
A Dietary Supplement
Brand IP Statement(s)
Copyright 2017 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.
Suggested/Recommended/Usage/Directions
Directions Take 1 capsule, 3 times daily, with meals.
General Statements
TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.
Please recycle!
FDA Disclaimer Statement
Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Graviola Fruit 450 mg by TerraVita Premium Collection label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Graviola Fruit 450 mg by TerraVita Premium Collection
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.
Graviola
Interacts with1 drug
Graviola (soursop) is a tropical fruit tree whose leaves, fruit, and bark are used in traditional medicine, especially in parts of South America, Afri...
Graviola monograph & interactionsOther (inactive) ingredients: Gelatin, Water. These complete the product’s ingredient list but are not active constituents.
Graviola Fruit 450 mg by TerraVita Premium Collection Drug Interactions
HelloPharmacist Interaction Report
TerraVita Premium Collection Graviola Fruit 450 mg has one documented interaction: with carbamazepine (Tegretol), an anti-seizure medication.
The concern is Moderate in severity. Graviola may lower carbamazepine levels in your blood—in rat studies, it reduced the drug's peak concentration by 35% and overall exposure by 46%, which could make the medication less effective at controlling seizures.
Read the full breakdown — every affected drug type, severity by severity
If you take carbamazepine, do not start graviola without talking to your doctor or pharmacist first. They'll need to monitor your seizure control and may need to adjust your carbamazepine dose.
You can use the medication checker on this page to confirm there are no other interactions with your specific medications, though this is the only drug interaction we have data for with this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Graviola Fruit 450 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Graviola Fruit 450 mg interact with 1 drug. Click any drug to see the details.
1 of the 1 ingredient in Graviola Fruit 450 mg interact with drugs. Each result below shows which ingredient is responsible. Graviola
CarbamazepineCarbatrol, Carnexiv, Equetro, Tegretol, Tegretol XR
How Carbamazepine interacts with Graviola Fruit 450 mg — through 1 ingredient. Tap an ingredient for the detail:
GraviolaCarbamazepine (tegretol) Moderate
Interaction Summary
Theoretically, graviola might decrease concentrations of carbamazepine when used concomitantly.
Read the full Graviola + Carbamazepine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Graviola Fruit 450 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Graviola
Carbamazepine (Tegretol)
Theoretically, graviola might decrease concentrations of carbamazepine when used concomitantly.
A study in rats shows that graviola extract reduces the area under the curve of carbamazepine by 46% and maximum concentration by 35% when compared with carbamazepine alone.
Brand information
Manufacturer and brand details for Graviola Fruit 450 mg, from the product label.
TerraVita Premium Collection
See all TerraVita Premium Collection products- Name
- TerraVita Fine Whole Herbs
- City
- Brampton
- State
- Ontario
Graviola Fruit 450 mg by TerraVita Premium Collection: Common Questions
Does Graviola Fruit 450 mg by TerraVita Premium Collection interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is graviola, and what is it used for?
What are the side effects of graviola?
Can I take graviola while pregnant or breastfeeding?
Does graviola interact with seizure medications?
How much graviola is in each capsule?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Graviola Fruit 450 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Graviola Fruit 450 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Graviola Fruit 450 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Graviola 4 references
- Caparros-Lefebvre D, Elbaz A. Possible relation of atypical parkinsonism in the French West Indies with consumption of tropical plants: a case-control study. Caribbean Parkinsonism Study Group. Lancet 1999;354:281-6. PubMed
- Gavamukulya Y, Wamunyokoli F, El-Shemy HA. Annona muricata: Is the natural therapy to most disease conditions including cancer growing in our backyard? A systematic review of its research history and future prospects. Asian Pac J Trop Med. 2017;10(9):835- PubMed
- Abu Soukhon AA, Abu-Qatouseh L, Mansoor K, et al. Cytotoxicity Activity of Graviola Fruit Extract with Carbamazepine and Valproic Acid Show Antagonistic and Indifferent Effects. Asian Pac J Cancer Prev 2023;24(6):1869-1875. PubMed
- Cleret de Langavant L, Roze E, Petit A, et al. Annonaceae Consumption Worsens Disease Severity and Cognitive Deficits in Degenerative Parkinsonism. Mov Disord 2022;37(12):2355-2366. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC