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Dietary supplement

Hair - Skin - Nails Ingredients & Drug Interactions

by BioSil

Capsule Category: Single Vitamin And Mineral
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Hair - Skin - Nails is a dietary supplement by BioSil with 2 active ingredients. Its ingredients are commonly taken for liver health and fatty liver, brain and memory support, prenatal nutrition and fetal development.Based on those ingredients, 16 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Choline. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Hair - Skin - Nails by BioSil

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

BioSil Hair - Skin - Nails has 2 active ingredients. Choline is a nutrient your body uses for various functions, including nerve and brain health.

Silicon is a mineral found naturally in foods and water that your body uses to support bone and connective tissue health. The capsules also contain microcrystalline cellulose (a binder), purified water, and a capsule shell — the standard inactive ingredients that hold everything together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Hair, skin, and nail health.
  • We looked for evidence on: Aging skin, Androgenic alopecia, Nail brittleness, Skin elasticity.
  • The closest evidence on file: Silicon is rated "Insufficient Reliable Evidence To Rate" for Aging skin (Natural Medicines).
  • Also on file: Silicon is rated "Insufficient Reliable Evidence To Rate" for Androgenic alopecia.

The evidence we hold is mixed and incomplete. Silicon is possibly effective for osteoporosis — the one condition where we have some supporting data.

For the other claims — hair loss, bone health, and nail strength — the evidence either isn't established in our records or is too limited to say whether the ingredients work. If you're hoping this will address a specific health concern, talk it over with your doctor or pharmacist about what the science actually supports.

The evidence, ingredient by ingredient Choline Silicon

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both choline and silicon are generally well tolerated in normal doses. Choline can cause a fishy body odor at any dose; at high doses (9 grams or more daily) it may also cause nausea, vomiting, diarrhea, and sweating.

Silicon from food and supplements is safe in typical amounts, though long-term safety at high doses hasn't been thoroughly studied. For pregnancy and breastfeeding: choline is rated Likely Safe — it's actually important during both periods — but use only prenatal doses or supplement amounts advised by your doctor.

Silicon, however, has insufficient safety data in pregnancy and lactation; the facts advise against supplemental use during these times. If you're pregnant or breastfeeding, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Choline Silicon

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Choline.
  • The most serious interaction on file is rated Minor.
  • For scale: 16 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take atropine or other anticholinergic medications, check with your doctor or pharmacist before starting this product — choline may reduce how well these drugs work. No other medication interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Only minor medication interactions are documented, and safety information is well characterized.

BioSil Hair - Skin - Nails is generally well tolerated and contains ingredients with some research behind them — especially silicon for bone health. If you take atropine or any anticholinergic medication (used for eye conditions or urinary issues), check your medications with us first.

Anyone pregnant or breastfeeding should talk with their doctor or pharmacist before starting, since silicon supplementation isn't recommended during those times.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Hair - Skin - Nails, straight from the product label.

Brand BioSil
Barcode (UPC) 5425010391828
Net contents 30 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Aug 22, 2017
DSLD ID 77061
Product type Single Vitamin And Mineral
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Hair - Skin - Nails by BioSil, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
5425010391828
IngredientAmount% DV
Choline100 mg18%
Silicon5 mg--

Other ingredients: Microcrystalline Cellulose, purified Water, Capsule Shell

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Consult your healthcare professional prior to use if you have or suspect a medical condition, are taking prescription drugs, or are pregnant or lactating.

Keep out of the reach of children.

Formulation

This product does not contain soy, dairy, egg, corn, wheat, gluten, fish/shellfish, nuts/tree nuts.

V Vegan Vegetarian

Storage

Store at 59-86(0)F (15-30(0)C). Protect from light and moisture.

Seals/Symbols

V Vegan Vegetarian

isura Non-GMO - Mass spec Documentation - Lab tested

Brand IP Statement(s)

ch-OSA, BioSil, the ch-OSA logo, the vegetarian logo and Advanced Collagen Generator are registered trademarks of Bio Minerals NV.

U.S. Patent #'s: 7,968,528 and 8,771,757

2017 Bio Minerals NV

Natural Factors

But it took BioSil's landmark discovery of ch-OSA to make it a reality. Its capacity to generate collagen with your own DNA fingerprint makes ch-OSA the genuine breakthrough in collagen.

ch-OSA, BioSil, the ch-OSA logo, the vegetarian logo and Advanced Collagen Generator are registered trademarks of Bio Minerals NV. The Clinical Facts box is a trademark of Bio Minerals NV.

Clinical facts Choline-stabilized orthosilicic acid (ch-OSA) Clinically proven dosage Clinically proven for skin 1 capsule, 2 times daily Clinically proven for hair 1 capsule, 2 times daily Clinically proven for nails 1 capsule, 2 times daily ch-OSA has been tested in rigorous double-blind placebo controlled clinical trials for both efficacy and safety. The results are published in peer reviewed medical journal (see insert for details).

BioSil Hair Skin Nails, with clinically proven ch-OSA, is specifically formulated to help nourish our body's 3 beauty proteins and restore them to more youthful levels.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

ch-OSA Advanced collagen generator

ch-OSA Original Formula

General Statements

Reduces fine lines and wrinkles Thickens and strengthens hair Strengthens nails Promotes healthy bones and joints

Clinically proven

Made in Belgium

The breakthrough in collagen! Collagen is essential for beautiful skin, hair and nails as well as healthy bones and joints. But starting at age 21, collagen diminishes 1% per year. By age 30, the signs become visible. For years, scientists searched for a method to give the human body the ability to regenerate its own collagen.

Nourish your body's 3 "beauty proteins" - naturally! The condition of your skin, hair, and nails depends on three proteins: Collagen "plumps out" skin, removing wrinkles and preventing them form forming. In addition, collagen is essential for strong, healthy bones and joints. Keratin is the protein that's packed into your hair shaft. It gives your hair thickness, body, strength, and elasticity. Plus, keratin gives your nails strength. Elastin gives your skin its ability to stretch and "bounce back" preventing fine lines and wrinkles. With age, collagen, keratin and elastin decline.

Strengthens hair First 36 weeks Break load (N) .58 .60 .65 .70 .73 Placebo 0.61 ch-OSA (2 caps/day) 0.69 13.1% stronger hair with ch-OSA

Reduces depth of wrinkles First 20 weeks Change in wrinkle depth -20% -15% -10% -5% 0 +5% +10% +15% +20% Placebo -11% ch-OSA (2 caps/day) 30% net improvement in wrinkle depth with ch-OSA

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Take one capsule, two times per day.

See for yourself

Hair - Skin - Nails by BioSil label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Hair - Skin - Nails by BioSil

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Choline

Interacts with
16 drugs
100 mg per serving Form: ch-OSA

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like egg...

Choline monograph & interactions

Silicon

No known
interactions
5 mg per serving Form: Choline-stabilized Orthosilicic Acid

Silicon is a trace mineral found in the body and in foods like oats, barley, and certain fruits and vegetables, and it is popular in supplements for h...

Silicon monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Purified Water, Capsule Shell. These complete the product’s ingredient list but are not active constituents.

Interaction report

Hair - Skin - Nails by BioSil Drug Interactions

Want to check YOUR meds against Hair - Skin - Nails?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
16Drugs
16 Minor

Ingredients driving the most interactions

Choline 16

Each ingredient & the kinds of drugs it affects

For each ingredient in Hair - Skin - Nails with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Choline1 drug type · 16 drugs

Atropine

Theoretically, choline might decrease the effects of atropine in the brain.
Animal research shows that administering choline one hour before administering atropine can attenuate atropine-induced decreases in brain levels of acetylcholine. Theoretically, concomitant use of choline and atropine may decrease the effects of atropine.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Hair - Skin - Nails, from the product label.

BioSil

See all BioSil products
Name
Bio Minerals NV
State
Destelbergen
Pharmacist Counseling Corner

Hair - Skin - Nails by BioSil: Common Questions

Does Hair - Skin - Nails by BioSil interact with any medications?
Yes. Based on its ingredients, Hair - Skin - Nails has a known interaction with 16 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Hair - Skin - Nails contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product really help with hair, skin, and nails?
Silicon is possibly effective for osteoporosis according to our data, but for hair growth, skin health, and nail strength, the evidence we hold is either too limited or not established. Talk with your doctor about whether this product is right for your specific goals.
Can I take this if I'm pregnant or breastfeeding?
Choline is rated Likely Safe and is actually important during both pregnancy and breastfeeding, but use only the doses your doctor recommends. Silicon, however, has insufficient safety data — the facts advise against supplements during pregnancy and breastfeeding. Check with your doctor or pharmacist before taking this product.
What are the side effects?
Choline is well tolerated in normal amounts, but it can cause a fishy body odor at any dose. At very high doses (9 grams or more daily), it may cause nausea, vomiting, diarrhea, and sweating. Silicon from supplements is generally safe, though long-term high-dose safety hasn't been well studied.
What is choline and why is it in this product?
Choline is a nutrient your body uses for nerve and brain function. It's included in this product because it supports overall health, though the evidence for hair, skin, and nail benefits specifically isn't well established in our data.
Are there any fillers or additives I should know about?
The inactive ingredients are microcrystalline cellulose (a binder), purified water, and the capsule shell — standard materials that hold the formula together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Hair - Skin - Nails is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Hair - Skin - Nails label
Sources

Sources & How We Checked

Hair - Skin - Nails's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 33 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Choline 14 references
  1. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  2. Cho E, Willett WC, Colditz GA, et al. Dietary choline and betaine and the risk of distal colorectal adenoma in women. J Natl Cancer Inst 2007;99:1224-31. PubMed
  3. Schmidt, C., Abicht, A., Krampfl, K., Voss, W., Stucka, R., Mildner, G., Petrova, S., Schara, U., Mortier, W., Bufler, J., Huebner, A., and Lochmuller, H. Congenital myasthenic syndrome due to a novel missense mutation in the gene encoding choline acetyl
  4. Tamminga, C., Smith, R. C., Chang, S., Haraszti, J. S., and Davis, J. M. Depression associated with oral choline. Lancet 10-23-1976;2(7991):905. PubMed
  5. Wood, J. L. and Allison, R. G. Effects of consumption of choline and lecithin on neurological and cardiovascular systems. Fed.Proc. 1982;41(14):3015-3021.
  6. Growdon, J. H. and Gelenberg, A. J. Choline and lecithin administration to patients with tardive dyskinesia. Trans.Am.Neurol.Assoc. 1978;103:95-99.
  7. Smith, C. M., Swash, M., Exton-Smith, A. N., Phillips, M. J., Overstall, P. W., Piper, M. E., and Bailey, M. R. Choline therapy in Alzheimer's disease. Lancet 8-5-1978;2(8084):318. PubMed
  8. Morrison, L. M. and W. F. Gonzales. Choline in coronary atherosclerosis. Amer.Heart J. 1950;39:729.
  9. Christie, J. G. Blackburn 1. M. Glen A. I. M. Zeisel S. Shering A. & Yates C. M. Effects of choline and lecithin on CSF choline levels and on cognitive functioning in patients with presenile dementia of the Alzheimer type. Nutrition and the brain 1979;5
  10. Sidhu N, Davies S, Nadarajah A, et al. Oral choline supplementation for postoperative pain. Br J Anaesth 2013;111(2):249-55. PubMed
  11. Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol spectrum disorders has high feasibility and tolerability. Nutr Res. 2013;33(11):897-904. PubMed
  12. Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol disorders: a randomized, double-blind, placebo-controlled trial. Am J Clin Nutr. 2015;102(5): 1113-25.
  13. Ross RG, Hunter SK, McCarthy L, et al. Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk. Am J Psychiatry. 2013;170(3):290-8. PubMed
  14. Food and Nutrition Board, Institute of Medicine. Choline. Dietary Reference Intakes: Thiamin, Riboflavin, Niacin, Vitamin B-6, Vitamin B-12, Pantothenic Acid, Biotin, and Choline. Washington D.C.: National Academy Press; 1998:390-422.

See these in context on the Choline monograph →

Silicon 19 references
  1. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  2. Jugdaohsingh R, Anderson SH, Tucker KL, et al. Dietary silicon intake and absorption. Am J Clin Nutr 2002;75:887-93. PubMed
  3. Ichiyanagi O, Sasagawa I, Adachi Y, et al. Silica urolithiasis without magnesium trisilicate intake. Urol Int 1998;61:39-42. PubMed
  4. Levison DA, Crocker PR, Banim S, Wallace DM. Silica stones in the urinary bladder. Lancet 1982;1:704-5. PubMed
  5. Lee MH, Lee YH, Hsu TH, et al. Silica stone--development due to long time oral trisilicate intake. Scand J Urol Nephrol 1993;27:267-9. PubMed
  6. Cruz Guerra, N. A., Gomez Garcia, M. A., Lovaco, Castellano F., Saez Garrido, J. C., Garcia, Cuerpo E., and Escudero, Barrilero A. [Silica urolithiasis: report of a new case]. Actas Urol.Esp 2000;24(2):202-204.
  7. Merget, R., Bauer, T., Kupper, H. U., Philippou, S., Bauer, H. D., Breitstadt, R., and Bruening, T. Health hazards due to the inhalation of amorphous silica. Arch Toxicol. 2002;75(11-12):625-634. PubMed
  8. Khuder, S. A., Peshimam, A. Z., and Agraharam, S. Environmental risk factors for rheumatoid arthritis. Rev Environ Health 2002;17(4):307-315. PubMed
  9. McLaughlin, J. K., Chow, W. H., and Levy, L. S. Amorphous silica: a review of health effects from inhalation exposure with particular reference to cancer. J Toxicol.Environ Health 4-25-1997;50(6):553-566. DOI
  10. Pelucchi, C., Pira, E., Piolatto, G., Coggiola, M., Carta, P., and La, Vecchia C. Occupational silica exposure and lung cancer risk: a review of epidemiological studies 1996-2005. Ann.Oncol. 2006;17(7):1039-1050. PubMed
  11. Gillissen, A., Gessner, C., Hammerschmidt, S., Hoheisel, G., and Wirtz, H. [Health significance of inhaled particles]. Dtsch.Med Wochenschr. 3-24-2006;131(12):639-644.
  12. Hu, J. F., Qu, H., and Wang, J. Z. [Meta analysis for relationship between exposure of free silicon dioxide and lung tumor]. Zhonghua Lao.Dong.Wei Sheng Zhi.Ye.Bing.Za Zhi. 2006;24(7):415-417.
  13. Jugdaohsingh, R. Silicon and bone health. J Nutr Health Aging 2007;11(2):99-110.
  14. Lacasse, Y., Martin, S., Gagne, D., and Lakhal, L. Dose-response meta-analysis of silica and lung cancer. Cancer Causes Control 2009;20(6):925-933. PubMed
  15. McCormic, Z. D., Khuder, S. S., Aryal, B. K., Ames, A. L., and Khuder, S. A. Occupational silica exposure as a risk factor for scleroderma: a meta-analysis. Int Arch Occup.Environ Health 2010;83(7):763-769. PubMed
  16. Haddad, F. S. and Kouyoumdjian, A. Silica stones in humans. Urol.Int 1986;41(1):70-76. PubMed
  17. Tervaert, J. W., Stegeman, C. A., and Kallenberg, C. G. Silicon exposure and vasculitis. Curr Opin.Rheumatol 1998;10(1):12-17. PubMed
  18. Steenland, K. and Stayner, L. Silica, asbestos, man-made mineral fibers, and cancer. Cancer Causes Control 1997;8(3):491-503. PubMed
  19. Boqué N, Valls RM, Pedret A, Puiggrós F, Arola L, Solà R. Relative absorption of silicon from different formulations of dietary supplements: a pilot randomized, double-blind, crossover post-prandial study. Sci Rep 2021;11(1):16479. PubMed

See these in context on the Silicon monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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