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Dietary supplement

He Huan Pi Ingredients & Drug Interactions

by Herbal Terra

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

He Huan Pi is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, low mood or mild depression, sleep trouble (insomnia).Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Albizzia julibrissin Bark Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of He Huan Pi by Herbal Terra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

He Huan Pi contains one active ingredient: Albizia julibrissin (silk tree) bark extract in a concentrated, dry form. The liquid itself is made up of alcohol, water, and glycerin as inactive ingredients—the extract is dissolved in that base so you can take it as a liquid.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Albizia Julibrissin product and its label doesn't state a use — see Albizia Julibrissin's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't have effectiveness ratings on file for Albizia julibrissin bark extract, so we can't tell you from our data whether it works for its intended purpose. If you're considering this product for a specific health goal, that's a good conversation to have with your pharmacist or doctor.

The evidence, ingredient by ingredient Albizia Julibrissin

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

This ingredient comes with caution flags. There's limited human safety data, so the advice is to use it carefully and under professional guidance.

The safety information also notes it was traditionally avoided during pregnancy and that there's no reliable safety data for breastfeeding—so if you're pregnant or nursing, talk with your doctor or pharmacist before taking it. No adverse effects (side effects from trial data) are on file, but that doesn't mean none occur; limited study of the ingredient is part of why the caution exists.

Side effects, ingredient by ingredient Albizia Julibrissin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Albizia Julibrissin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 248 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check any sleeping pills, sedatives, anti-anxiety medications, opioids, or other drugs that slow your brain and nervous system. The extract can enhance their effects (moderate severity).

Run your exact medications through the checker below to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

He Huan Pi may be worth considering if you're looking for what traditional herbalism offers and your doctor or pharmacist has cleared it with your other medications. If you take any sedatives, sleep aids, anti-anxiety drugs, or opioids, you'll need to check first—this product can amplify their effects.

If you're pregnant, breastfeeding, or taking CNS depressants, check with your pharmacist before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about He Huan Pi, straight from the product label.

Brand Herbal Terra
Barcode (UPC) 7238360243390
Net contents 2 Fluid Ounce(s); 60 mL
Market status On market
Date entered into DSLD Aug 22, 2025
DSLD ID 325087
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for He Huan Pi by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
60
UPC/BARCODE
7238360243390
IngredientAmount% DV
Albizzia julibrissin Bark Extract, Dry983 mg--

Other ingredients: Alcohol, Water, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz. of juice or water up to 4 times a day.

Precautions

We recommend to seek expert medical advice before taking. May have contraindications and cause adverse reaction.

Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications.

Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications. Keep out of the reach of children!

Do not use if you are allergic to any ingredients.

Storage

Store in a cool, dry, dark place.

FDA Disclaimer Statement

This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.

Formulation

cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.

Sugar free

Expertly extracted 100% natural Premium product

Organic alcohol

No artificial ingredients, color additives, fillers or binders.

Natural Gluten free

Formula

Albizzia julibrissin

Organic alcohol

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Made in USA

General Statements

Organic raw material.

See for yourself

He Huan Pi by Herbal Terra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in He Huan Pi by Herbal Terra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.

Albizzia julibrissin Bark Extract, Dry

Interacts with
248 drugs
983 mg per serving

Albizia julibrissin (Persian silk tree, He Huan) is a plant used in traditional Chinese medicine, mainly the flower and bark, for calming the mind, li...

Albizzia julibrissin Bark Extract, Dry monograph & interactions

Other (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

He Huan Pi by Herbal Terra Drug Interactions

Want to check YOUR meds against He Huan Pi?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
248Drugs
248 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in He Huan Pi with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Albizzia julibrissin Bark Extract, Dry1 drug type · 248 drugs

Cns Depressants

Animal research suggests that certain constituents from Albizia julibrissin flowers can potentiate pentobarbital-induced sleeping time in mice. Theoretically, Albizia julibrissin might enhance the therapeutic and adverse effects of CNS depressants.
Some CNS depressants include pentobarbital (Nembutal), phenobarbital (Luminal), secobarbital (Seconal), clonazepam (Klonopin), lorazepam (Ativan), zolpidem (Ambien), and others.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for He Huan Pi, from the product label.

Herbal Terra

See all Herbal Terra products
Name
Herbal Terra LLC
Phone Number
+18083857868
Web Address
herbalterra.com
Pharmacist Counseling Corner

He Huan Pi by Herbal Terra: Common Questions

Does He Huan Pi by Herbal Terra interact with any medications?
Yes. Based on its ingredients, He Huan Pi has a known interaction with 248 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
He Huan Pi contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is He Huan Pi safe to take while pregnant?
The safety data advises against using it in pregnancy. If you're pregnant or planning to become pregnant, talk with your doctor or pharmacist before taking this product.
Can I use He Huan Pi while breastfeeding?
There's no reliable safety data for breastfeeding, so the guidance is to avoid it while nursing. Talk with your pharmacist or doctor for personalized advice.
What does Albizia julibrissin bark do?
We don't have effectiveness information on file, so we can't tell you from our data what it's designed to do. Your pharmacist or a Traditional Chinese Medicine practitioner would be a good resource.
Are there any side effects listed for this product?
No adverse effects from trials are on file. That said, human safety data on this ingredient is limited, so if you notice anything unusual after taking it, let your pharmacist or doctor know.
What are the inactive ingredients?
The liquid base is made of alcohol, water, and glycerin. If any of those are a concern for you, mention it to your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

He Huan Pi label
Sources

Sources & How We Checked

He Huan Pi's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Albizia Julibrissin 1 reference
  1. Kang, T. H., Jeong, S. J., Kim, N. Y., Higuchi, R., and Kim, Y. C. Sedative activity of two flavonol glycosides isolated from the flowers of Albizzia julibrissin Durazz. J Ethnopharmacol 2000;71(1-2):321-323. PubMed

See these in context on the Albizia Julibrissin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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