HepatoPro Ingredients & Drug Interactions
What is this page for?
First and foremost: checking HepatoPro against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
HepatoPro is a dietary supplement by Life Extension with 1 active ingredient. Its ingredients are commonly taken for liver health, memory and brain support, ulcerative colitis.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of HepatoPro by Life Extension
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
HepatoPro has one active ingredient: polyenylphosphatidylcholine, a compound that delivers choline and phospholipids — building blocks your cells use for structure and function. The rest is inactive ingredients (gelatin capsule, medium chain triglyceride, sorbitol, glycerin, ethanol, purified water, and silica) that help deliver and preserve the softgel.
Does it work?
Insufficient evidence
The evidence is mixed. Polyenylphosphatidylcholine is possibly effective for ulcerative colitis (a type of inflammatory bowel disease), but for nonalcoholic fatty liver disease, alcohol-related liver disease, Alzheimer disease, and anxiety, the evidence isn't strong enough to rate.
That doesn't mean it doesn't work — it means reliable studies are still lacking.
How safe is it?
Well-documented data
Polyenylphosphatidylcholine is generally well tolerated, but it can cause digestive side effects. The most common ones taken by mouth are altered taste, bloating, diarrhea, itching, nausea, sweating, and vomiting — especially if you take a large dose.
Very high doses (30 grams per day) are more likely to cause stomach upset and diarrhea. Choline is needed during pregnancy, but supplement safety beyond what's in food hasn't been well studied — talk with your doctor before taking this while pregnant or breastfeeding.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. Still, run your medications through the checker below — it only takes a minute and it's the best way to be sure.
The bottom line
Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
HepatoPro might be worth considering if you're dealing with ulcerative colitis or want to support liver health, though the evidence for liver disease is still thin. If you're pregnant, breastfeeding, or take any medications regularly, check with your pharmacist or doctor first.
If digestive upset happens, a lower dose or taking it with food may help.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about HepatoPro, straight from the product label.
| Brand | Life Extension |
|---|---|
| Barcode (UPC) | 737870139362 |
| Net contents | 60 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Apr 24, 2025 |
| DSLD ID | 328474 |
| Product type | Fat/fatty Acid |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for HepatoPro by Life Extension, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 10 Calorie(s) | -- |
| Total Fat | 1 Gram(s) | 1% |
| Polyenylphosphatidylcholine | 900 mg | -- |
Other ingredients: Gelatin, Medium Chain Triglyceride, Sorbitol, Glycerin, Ethanol, Water, Purified, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Scan for product info
Precautions
Read the entire label and follow the directions carefully prior to use.
Warnings: Keep out of reach of children.
Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Contains soybeans.
To report a serious adverse event or obtain product information, contact 1-866-280-2852.
Suggested/Recommended/Usage/Directions
Directions: Take one (1) softgel two to three times daily, or as recommended by a healthcare practitioner.
Storage
Protect from heat and light.
Store tightly closed in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formula
Polyunsaturated phosphatidylcholine 900 mg
Formulation
Gluten free Non GMO LE Certified
Supports a healthy liver
Seals/Symbols
Non GMO LE Certified
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
HepatoPro by Life Extension label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in HepatoPro by Life Extension
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.
Polyenylphosphatidylcholine
No knowninteractions
Phosphatidylcholine is a phospholipid that is part of every cell membrane and a source of choline. People take it for liver, brain, and gut health, bu...
Polyenylphosphatidylcholine monograph & interactionsOther (inactive) ingredients: Gelatin, Medium Chain Triglyceride, Sorbitol, Glycerin, Ethanol, Water, Purified, Silica. These complete the product’s ingredient list but are not active constituents.
HepatoPro by Life Extension Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in HepatoPro. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for HepatoPro, from the product label.
Life Extension
See all Life Extension products- Name
- Quality Supplements and Vitamins, Inc.
- City
- Ft. Lauderdale
- State
- FL
- ZipCode
- 33309
- Phone Number
- 1-866-280-2852
- Web Address
- LifeExtension.com
HepatoPro by Life Extension: Common Questions
Does HepatoPro by Life Extension interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What does polyenylphosphatidylcholine do?
Can I take this if I'm pregnant?
Can I take this while breastfeeding?
What side effects might I notice?
Is this safe to take long term?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if HepatoPro is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind HepatoPro’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
HepatoPro's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 15 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Phosphatidylcholine 15 references
- Domino EF, May WW, Demetriou S, et al. Lack of clinically significant improvement of patients with tardive dyskinesia following phosphatidylcholine therapy. Biol Psychiatry 1985;20:1189-96. PubMed
- Aronson PJ, Lorincz AL. Promotion of palmar sweating with oral phosphatidylcholine. Acta Derm Venereol 1985;65:19-24. DOI
- Hexsel DM, Serra M, de Oliveira Dal'Forno T, et al. Cosmetic uses of injectable phosphatidylcholine on the face. Otolaryngol Clin North Am 2005;38:1119-29. PubMed
- Kopera D, Binder B, Toplak H, et al. Histopathologic changes after intralesional application of phosphatidylcholine for lipoma reduction: report of a case. Am J Dermatopathol 2006;28:331-3. PubMed
- Rittes PG. The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads. Dermatol Surg 2001;27:391-2. PubMed
- Rotunda AM, Kolodney MS. Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 2006;32:465-80. PubMed
- Hexsel D, Serra M, Mazzuco R, et al. Phosphatidylcholine in the treatment of localized fat. J Drugs Dermatol 2003;2:511-8.
- Hasengschwandtner F. Phosphatidylcholine treatment to induce lipolysis. Cosmet Dermatol 2005;4:308-13. PubMed
- Rittes PG. The use of phosphatidylcholine for correction of localized fat deposits. Aesthetic Plast Surg 2003;27:315-8. PubMed
- Ablon G, Rotunda AM. Treatment of lower eyelid fat pads using phosphatidylcholine: clinical trial and review. Dermatol Surg 2004;30:422-7. PubMed
- Loguercio C, Andreone P, Brisc C, et al. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Free Radic Biol Med 2012;52(9):1658-65. PubMed
- Panos, J. M., Palson, R., Johnson, R., Portmann, B., and Williams, R. Polyunsaturated phosphatidylcholine for acute alcoholic hepatitis: a double blind randomized placebo controlled trial. Eur.J.Gastroenterol 1990;2:351-355.
- Stremmel W, Braun A, Hanemann A, Ehehalt R, Autschbach F, Karner M. Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study. J Clin Gastroenterol 2010;44(5):e101-7. PubMed
- Stremmel W, Ehehalt R, Autschbach F, Karner M. Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial. Ann Intern Med. 2007;147(9):603-10. PubMed
- Stremmel W, Vural H, Evliyaoglu O, Weiskirchen R. Delayed Release Phosphatidylcholine is Effective for Treatment of Ulcerative Colitis: A Meta-Analysis. Dig Dis 2021;39(5):508-515. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC