No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

High Plains Collagen Hydrolysate Powder Ingredients & Drug Interactions

by Swanson

Powder Category: Amino Acid/protein
No known interaction
The interaction bottom line No known interaction

High Plains Collagen Hydrolysate Powder is a dietary supplement by Swanson with 2 active ingredients. Its ingredients are commonly taken for skin health and wrinkles, joint pain and osteoarthritis, bone health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of High Plains Collagen Hydrolysate Powder by Swanson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This powder contains one active ingredient: collagen hydrolysate, a processed form of collagen that your body can absorb and use as a source of protein and amino acids. Collagen is the most abundant protein in your skin, joints, and connective tissue, so hydrolyzed (broken-down) collagen is meant to support those structures from the inside.

The product has no inactive fillers or other ingredients listed — it's just the collagen peptides themselves.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Collagen Peptides's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: maintain cartilage, joints, tendons, ligaments.
  • We looked for evidence on: Joint pain, Knee pain, Osteoarthritis, Tendinopathy, Sprains, Joint flexibility — and 2 related terms.
  • The closest evidence on file: Collagen Peptides is rated "Insufficient Reliable Evidence To Rate" for Osteoarthritis (Natural Medicines).
  • Also on file: Collagen Peptides is rated "Insufficient Reliable Evidence To Rate" for Knee pain, Joint pain, Sprains, Tendinopathy.

The evidence is mixed. Collagen peptides are possibly effective for aging skin and dry skin — meaning there's some research support, but it's not yet conclusive.

For muscle strength, the data suggests it's probably ineffective. For acne and athletic performance, we don't have enough reliable evidence to rate it one way or the other.

If you're thinking about this powder mainly for joint or bone health, the data we hold doesn't address those uses.

The evidence, ingredient by ingredient Collagen Peptides

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Collagen hydrolysate is generally well tolerated as a dietary protein. Side effects — when they occur — are rare and mild, and include nausea, indigestion (dyspepsia), diarrhea, and bloating (flatulence).

If you're pregnant, this product hasn't been well studied, so talk with your doctor first. If you're breastfeeding, safety data is sparse; caution is advised, and checking with your doctor or pharmacist is a good idea.

Side effects, ingredient by ingredient Collagen Peptides

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for collagen hydrolysate. You don't need to check your medications against this ingredient before starting.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

If you're interested in a collagen supplement for aging or dry skin and have no pregnancy or breastfeeding concerns, this product carries no documented drug interactions and is generally well tolerated. Expect mild digestive side effects to be uncommon.

Talk to your pharmacist if you're pregnant, breastfeeding, or have any questions about whether it fits your goals.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about High Plains Collagen Hydrolysate Powder, straight from the product label.

Brand Swanson
Barcode (UPC) 087614116570
Net contents 16 Ounce(s); 1 Pound(s); 454 Gram(s)
Market status On market
Date entered into DSLD Jun 16, 2022
DSLD ID 265636
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for High Plains Collagen Hydrolysate Powder by Swanson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4.2 Gram(s)
Maximum serving Sizes:
4.2 Gram(s)
Servings per container
108
UPC/BARCODE
087614116570
IngredientAmount% DV
Protein4 Gram(s)--
Calories15 Calorie(s)--
Collagen Hydrolysate4.2 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

swanson.com or call 1-800-437-4148

Science-Backed quality since 1969

Typical Amino Acid Profile: Glycine 882 mg Proline 538 mg Hydroxyproline 512 mg Glutamic Acid 433 mg Alanine 374 mg Arginine 307 mg Aspartic Acid 252 mg Lysine 147 mg Serine 130 mg Leucine 113 mg Valine 101 mg Phenylalanine 88 mg Threonine 80 mg Isoleucine 63 mg Hydroxylysine 63 mg Histidine 46 mg Tyrosine 42 mg Methionine 38 mg

Formulation

Helps maintain cartilage, tendons and ligaments Supports joint integrity, movement and flexibility

Note: Product contains a desiccant packet to maintain freshness.

Joint Health and Mobility

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, mix one scoop (4.2 g) in an 8 ounce glass of water or juice twice per day. Scoop included.

Precautions

Do not eat the desiccant packet.

Warning: For adults only.

Consult your healthcare provider before using this or any product if you are pregnant or nursing, taking medication or have a medical condition.

Keep out of reach of children.

Do not use if seal is broken.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

Collagens Type I & III

FDA Statement of Identity

Dietary Supplement

See for yourself

High Plains Collagen Hydrolysate Powder by Swanson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in High Plains Collagen Hydrolysate Powder by Swanson

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size4.2 Gram(s) Dosage formPowder Servings per container108 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Protein

4 Gram(s) per serving

Collagen Hydrolysate

No known
interactions
4.2 Gram(s) per serving Form: Bovine

Collagen peptides are a well-absorbed form of protein that may modestly improve skin elasticity and joint comfort for some people, though evidence is...

Collagen Hydrolysate monograph & interactions
Interaction report

High Plains Collagen Hydrolysate Powder by Swanson Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in High Plains Collagen Hydrolysate Powder. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for High Plains Collagen Hydrolysate Powder, from the product label.

Swanson

See all Swanson products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
swanson.com
Pharmacist Counseling Corner

High Plains Collagen Hydrolysate Powder by Swanson: Common Questions

Does High Plains Collagen Hydrolysate Powder by Swanson interact with any medications?
We do not currently list a known interaction for the mapped ingredients in High Plains Collagen Hydrolysate Powder. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
High Plains Collagen Hydrolysate Powder contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this collagen powder work for joint or bone health?
The data we hold doesn't cover joint or bone health. The evidence we have addresses aging skin, dry skin, muscle strength, acne, and athletic performance — so if those aren't your main goals, you'd want to talk with your pharmacist about what the research actually supports for your needs.
What side effects might I get?
Nausea, indigestion, diarrhea, and bloating can happen, but they're rare. Most people tolerate collagen hydrolysate well as a protein source.
Is it safe to use while pregnant?
Collagen hydrolysate hasn't been well studied in pregnancy. Check with your doctor before using it if you're pregnant — they can help you decide based on your individual situation.
Can I take it if I'm breastfeeding?
Safety data during breastfeeding is sparse. Talk with your doctor or pharmacist before using it — they'll help you weigh what we know and what we don't.
Does this powder have fillers or other ingredients?
No — it's just collagen hydrolysate. There are no inactive fillers or other added ingredients in this product.
Can I take this with my medications?
Collagen hydrolysate has no known interactions with medications, so there's no documented conflict. Still, if you have questions about your specific drugs, a quick check with your pharmacist is never a bad idea.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if High Plains Collagen Hydrolysate Powder is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

High Plains Collagen Hydrolysate Powder label
Go deeper

The Full Monographs Behind High Plains Collagen Hydrolysate Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

High Plains Collagen Hydrolysate Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Collagen Peptides 2 references
  1. Trc T, Bohmová J. Efficacy and tolerance of enzymatic hydrolysed collagen (EHC) vs. glucosamine sulphate (GS) in the treatment of knee osteoarthritis (KOA). Int Orthop. 2011;35(3):341-8. PubMed
  2. Evans M, Lewis ED, Zakaria N, Pelipyagina T, Guthrie N. A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity. J Cosmet Dermatol. 2021;20(3):825-834. PubMed

See these in context on the Collagen Peptides monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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