HistDAO Ingredients & Drug Interactions
by XYMOGEN
What is this page for?
First and foremost: checking HistDAO against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
HistDAO is a dietary supplement by XYMOGEN with 1 active ingredient.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of HistDAO by XYMOGEN
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
None of the active ingredients could be matched to our evidence database, so intended use can't be graded.
Why this rating?
- None of the active ingredients could be matched to a HelloPharmacist monograph, so intended use can't be graded against our evidence data.
Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.
Why this rating?
- The label discloses an exact amount for 0 of its 1 active ingredient.
- “Pig Kidney” is listed as a grouped ingredient — the label gives one combined amount (4.20 mg) without saying how much of each component you get.
None of the active ingredients could be matched to our interaction database.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was nothing to check interactions against.
None of the active ingredients could be matched to our safety data.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was no safety data to measure.
HelloPharmacist summaryFormula with limited ingredient disclosure with no assessable stated purpose. Medication interactions could not be assessed, and safety information could not be assessed.
Assessment coverage: 0 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about HistDAO, straight from the product label.
| Brand | XYMOGEN |
|---|---|
| Barcode (UPC) | 722537512503 |
| Net contents | 60 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2025 |
| DSLD ID | 335479 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for HistDAO by XYMOGEN, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Pig Kidney | 4.2 mg | -- |
| Diamine Oxidase | 0 NP | -- |
Other ingredients: Microcrystalline Cellulose, Hydroxypropyl Cellulose, Ethylcellulose, Sodium Alginate, Hydroxypropyl Methylcellulose, Medium Chain Triglyceride, Stearic Acid, Oleic Acid, Microcrystalline Cellulose, Sodium Starch Glycolate, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Supports healthy degradation of food-derived histamine
Formulated to exclude: Wheat, gluten, corn, yeast, soy, dairy products, fish, shellfish, peanuts, tree nuts, egg, sesame, ingredients derived from genetically modified organisms (GMOs), artificial colors, and artificial sweeteners.
FDA Statement of Identity
Dietary Supplement
General Statements
Scan to learn more!
Brand IP Statement(s)
Xymogen Exclusive professional formulas
DAO Enzyme manufactured by DR HEALTHCARE, S.L.U., for XYMOGEN under Patents
Copyright 2023 XYMOGEN
Suggested/Recommended/Usage/Directions
Directions: Take one tablet no more than 15 minutes before the consumption of histamine-rich foods, or take as directed by your healthcare professional.
Precautions
Consult your healthcare professional prior to use.
Individuals taking medication should discuss potential interactions with their healthcare professional.
Storage: Keep closed in a cool, dry place out of reach of children.
Formula
HistDAO provides a concentrated source of diamine oxidase (DAO)-the main enzyme responsible for the degradation of ingested histamine. This formula delivers the clinically researched dose of DAO in an easy-to-swallow, gastro-resistant mini-tablet, which is essential for releasing DAO in the small intestine, where it breaks down food-derived histamine. HistDAO does not manage or address antibody-related or IgE-related food allergies.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Storage
Storage: Keep closed in a cool, dry place out of reach of children.
Seals/Symbols
GMP compliant third-party verified
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
HistDAO by XYMOGEN label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in HistDAO by XYMOGEN
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.
Pig Kidney
- › Diamine Oxidase
Other (inactive) ingredients: Microcrystalline Cellulose, Hydroxypropyl Cellulose, Ethylcellulose, Sodium Alginate, Hydroxypropyl Methylcellulose, Medium Chain Triglyceride, Stearic Acid, Oleic Acid, Microcrystalline Cellulose, Sodium Starch Glycolate, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
HistDAO by XYMOGEN Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in HistDAO. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for HistDAO, from the product label.
XYMOGEN
See all XYMOGEN products- Name
- XYMOGEN Exclusive Professional Formulas
- Street Address
- 6900 Kingspointe Pkwy.
- City
- Orlando
- State
- FL
- ZipCode
- 32819
- Phone Number
- 800-647-6100
- Web Address
- www.xymogen.com
HistDAO by XYMOGEN: Common Questions
Does HistDAO by XYMOGEN interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if HistDAO is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
Sources & How We Checked
HistDAO's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC