No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Holly Flower Essence Ingredients & Drug Interactions

by Flower Essence Services

Liquid Category: Botanical
No known interaction
The interaction bottom line No known interaction

Holly Flower Essence is a dietary supplement by Flower Essence Services with 1 active ingredient. Its ingredients are commonly taken for fever, cough and chest congestion, joint pain (traditional use).We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Holly Flower Essence by Flower Essence Services

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This product contains one active ingredient: an infusion of holly leaf (Ilex aquifolium) at a 1:6000 dilution. Holly leaf has been used in traditional herbalism, though modern safety research on it is sparse.

The liquid also contains water and brandy as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Holly product and its label doesn't state a use — see Holly's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We hold no effectiveness ratings for holly leaf in our data. The evidence to support its use isn't established in the studies we have on file.

The evidence, ingredient by ingredient Holly

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Holly carries real safety red flags. Orally, holly leaf can irritate your stomach and intestines, causing nausea, vomiting, and diarrhea.

The spines on the leaf itself may scrape or puncture your mouth or throat. Holly berries are toxic — even 2 berries can cause vomiting and diarrhea in small children, and 20 to 30 berries can be fatal — though this product is a leaf preparation, not the berries.

There isn't enough safety data to know if it's okay during pregnancy or while breastfeeding. The safety notes advise against it in both cases.

If you're pregnant, planning to become pregnant, or nursing, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Holly

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for this ingredient. However, because safety data on holly leaf is limited, run through any specific medications you take with your doctor or pharmacist before starting.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Holly Flower Essence is a lightly researched product with limited evidence of benefit and some documented potential for stomach irritation. If you're interested in trying it, check with your doctor or pharmacist first — especially if you're pregnant, breastfeeding, or have a history of digestive problems.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Holly Flower Essence, straight from the product label.

Brand Flower Essence Services
Barcode (UPC) 782932210152
Net contents 1 fl. Oz.; 30 mL
Market status On market
Date entered into DSLD Jan 24, 2014
DSLD ID 29773
Product type Botanical
Supplement form Liquid
Dietary claims / uses No Claim
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Holly Flower Essence by Flower Essence Services, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 Drop(s)
Maximum serving Sizes:
4 Drop(s)
UPC/BARCODE
782932210152
IngredientAmount% DV
infusion (1:6000) of Ilex aquifolium0 NP--

Other ingredients: Water, Brandy

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Four drops, four times daily

Seals/Symbols

Healingherbs

DEMETER

Formulation

Certified organic by Stellar Certification Services, Inc.

Brand IP Statement(s)

Certified Biodynamic by the Demeter Association, Inc.

General Statements

BEST BY 06/2021 110615 Prepared according to the original methods of Dr. Edward Bach.

FDA Statement of Identity

herbal supplement

General

110615

See for yourself

Holly Flower Essence by Flower Essence Services label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Holly Flower Essence by Flower Essence Services

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size4 Drop(s) Dosage formLiquid Amounts shown are per serving.

0 NP per serving

Holly (Ilex aquifolium) is a common ornamental shrub whose bright red berries are poisonous and should never be eaten. There is very little reliable h...

Infusion (1:6000) of Ilex aquifolium monograph & interactions

Other (inactive) ingredients: Water, Brandy. These complete the product’s ingredient list but are not active constituents.

Interaction report

Holly Flower Essence by Flower Essence Services Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Holly Flower Essence. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Holly Flower Essence, from the product label.

Flower Essence Services

See all Flower Essence Services products
Phone Number
800-548-0075
Pharmacist Counseling Corner

Holly Flower Essence by Flower Essence Services: Common Questions

Does Holly Flower Essence by Flower Essence Services interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Holly Flower Essence. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Holly Flower Essence contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe if I'm pregnant or breastfeeding?
No — there isn't enough safety data, and the guidance advises against it in both pregnancy and while breastfeeding. Talk with your doctor or pharmacist before taking it if you're pregnant, planning to become pregnant, or nursing.
Can holly leaf cause stomach upset?
Yes. Orally, holly leaf can irritate your digestive tract and cause nausea, vomiting, and diarrhea. The spines on the leaf may also scratch the inside of your mouth or throat.
Why is this product so diluted (1:6000)?
The facts on file don't explain the dilution ratio. That's a question for the manufacturer or your pharmacist — they can tell you why they chose that strength.
Does holly leaf actually work for anything?
We don't hold effectiveness ratings for holly leaf. The evidence to support its use isn't established in the data we have.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Holly Flower Essence is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Holly Flower Essence label
Go deeper

The Full Monographs Behind Holly Flower Essence’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Holly Flower Essence's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Holly 2 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

See these in context on the Holly monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring