No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Holly Flower Essence Ingredients & Drug Interactions

by Flower Essence Services

Liquid Category: Botanical
No known interaction
The interaction bottom line No known interaction

Holly Flower Essence is a dietary supplement by Flower Essence Services with 1 active ingredient. Its ingredients are commonly taken for fever, cough and chest congestion, joint pain (traditional use).We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Holly Flower Essence by Flower Essence Services

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This product contains one active ingredient: an infusion of Ilex aquifolium (holly leaf) at a 1:6000 concentration. The other ingredients are water and brandy, which serve as the liquid base and preservative.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Holly product and its label doesn't state a use — see Holly's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We hold no effectiveness data for holly leaf in the facts available to us, so we cannot tell you whether this product is expected to work for any particular purpose.

The evidence, ingredient by ingredient Holly

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Holly leaf preparations carry caution: ingestion can cause stomach upset, diarrhea, nausea, and vomiting. The spines on holly leaves may physically irritate or tear skin and mucous membranes.

Holly berries are toxic — even a small number (2 or more) can cause vomiting and diarrhea in young children, and 20–30 berries can be fatal. The facts note there is little safety data on leaf preparations overall.

During pregnancy and breastfeeding, there is no safety data for this product, so the safety data advises against use. Talk with your doctor or pharmacist before taking it if you are pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient Holly

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredient we could check. That does not mean none exist — it means the research we hold did not find any.

Still, talk with your doctor or pharmacist before you start, especially given the limited safety data on this plant.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Because this product's safety profile is poorly understood and holly leaf can cause stomach upset and other effects, it is not a straightforward choice. If you are pregnant, breastfeeding, or have young children in your home, avoid it.

Before you start, talk it over with your doctor or pharmacist to see if it is right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Holly Flower Essence, straight from the product label.

Brand Flower Essence Services
Barcode (UPC) 782932220151
Net contents 0.25 fl. Oz.; 7.5 mL
Market status On market
Date entered into DSLD Jan 24, 2014
DSLD ID 29771
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, No Claim
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Holly Flower Essence by Flower Essence Services, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 Drop(s)
Maximum serving Sizes:
4 Drop(s)
UPC/BARCODE
782932220151
IngredientAmount% DV
infusion (1:6000) of Ilex aquifolium0 NP--

Other ingredients: Water, brandy

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

herbal supplement

Suggested/Recommended/Usage/Directions

Suggested use: four drops, four times daily

Formulation

Certified organic by Stellar Certification Services, Inc.

Seals/Symbols

Healingherbs

DEMETER

Brand IP Statement(s)

Demeter-certified Biodynamic

General Statements

BEST BY 04/2022 120419

General

120419

See for yourself

Holly Flower Essence by Flower Essence Services label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Holly Flower Essence by Flower Essence Services

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size4 Drop(s) Dosage formLiquid Amounts shown are per serving.

0 NP per serving

Holly (Ilex aquifolium) is a common ornamental shrub whose bright red berries are poisonous and should never be eaten. There is very little reliable h...

Infusion (1:6000) of Ilex aquifolium monograph & interactions

Other (inactive) ingredients: Water, Brandy. These complete the product’s ingredient list but are not active constituents.

Interaction report

Holly Flower Essence by Flower Essence Services Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Holly Flower Essence. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Holly Flower Essence, from the product label.

Flower Essence Services

See all Flower Essence Services products
Phone Number
800-548-0075
Pharmacist Counseling Corner

Holly Flower Essence by Flower Essence Services: Common Questions

Does Holly Flower Essence by Flower Essence Services interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Holly Flower Essence. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Holly Flower Essence contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is holly leaf safe to take by mouth?
Holly leaf can cause stomach upset, diarrhea, nausea, and vomiting. There is little safety data on leaf preparations of this plant overall, so the caution level is higher than for many supplements. If you have a sensitive stomach or any health concerns, check with your doctor or pharmacist first.
Is this safe during pregnancy?
No. There is no safety data for holly leaf during pregnancy, so it is advised against. Talk with your doctor or pharmacist if you are pregnant or planning to become pregnant.
Is this safe while breastfeeding?
No. There is no safety data for holly leaf while breastfeeding, so it is advised against. Talk with your doctor or pharmacist if you are breastfeeding.
What are holly berries, and why do the facts mention them?
Holly berries are the fruit of the holly plant and are toxic if swallowed — even just 2 can cause vomiting and diarrhea in small children. This product is a leaf infusion, not berries, but the facts mention berries to warn about accidental ingestion of the whole plant, especially in homes with young children.
Does this product interact with any medications?
No interactions are documented in our data for the ingredient we could check. That doesn't guarantee none exist — it means the research we hold did not find any. Before you start, check your exact medications with the search tool on this page, and talk with your doctor or pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Holly Flower Essence is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Holly Flower Essence label
Go deeper

The Full Monographs Behind Holly Flower Essence’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Holly Flower Essence's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Holly 2 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

See these in context on the Holly monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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