No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Homotaurine 100 mg Ingredients & Drug Interactions

by SuperSmart

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Homotaurine 100 mg is a dietary supplement by SuperSmart with 1 active ingredient. Its ingredients are commonly taken for memory support, brain and cognitive health, alzheimer's disease (investigational).We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Homotaurine 100 mg by SuperSmart

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: homotaurine, 100 mg per capsule. The inactive ingredients are acacia gum and white rice bran, which are fillers and binders that make up the capsule.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Homotaurine's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Brain support.
  • We looked for evidence on: Alzheimer disease, Cognitive impairment, Memory, Neuroprotection.
  • The closest evidence on file: Homotaurine is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease (Natural Medicines).
  • Also on file: Homotaurine is rated "Insufficient Reliable Evidence To Rate" for Cognitive impairment.

The evidence for homotaurine isn't established in our data. The product has been studied for Alzheimer disease, cognitive impairment, glaucoma, and Parkinson disease, but we hold insufficient reliable evidence to rate it for any of those uses.

That doesn't mean it doesn't work — it means the studies so far haven't given us enough clarity to say one way or the other.

The evidence, ingredient by ingredient Homotaurine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

In clinical trials, homotaurine was generally well tolerated. The most common side effects reported were nausea, vomiting, diarrhea, dizziness, headache, and sleep problems.

Nausea and vomiting appear dose-dependent — they occurred in 5% to 30% of people taking 50–150 mg twice daily, though some large studies saw similar rates in the placebo group too. Long-term safety as a supplement hasn't been well established.

The safety data advises against use during pregnancy and while breastfeeding because there isn't enough information to know either way. Talk with your doctor or pharmacist about whether this product is right for you.

Side effects, ingredient by ingredient Homotaurine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for homotaurine. You can search your medications on this page to confirm, but based on what we hold, there's no major concern here.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

Homotaurine is a compound that's been studied for cognitive and neurological conditions, but we don't have enough evidence to say whether it works for those purposes. It appears generally well tolerated in short-term trials, though nausea, dizziness, and headache can occur.

If you're thinking about taking it — especially if you're pregnant, breastfeeding, or have a health condition — talk it over with your doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Homotaurine 100 mg, straight from the product label.

Brand SuperSmart
Barcode (UPC) 5453003826613
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jun 23, 2021
DSLD ID 250586
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Homotaurine 100 mg by SuperSmart, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
1 Vegetarian Capsule(s)
Servings per container
30
UPC/BARCODE
5453003826613
IngredientAmount% DV
Homotaurine100 mg--

Other ingredients: Acacia Gum, White Rice Bran

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Brain support

FDA Statement of Identity

Dietary Supplement

Formula

Homotaurine 100 mg per day

Each capsule contains 50 mg of homotaurine.

Suggested/Recommended/Usage/Directions

Recommended Use: Adults. Take one capsule morning and evening during meals.

Precautions

Precautions: Do not exceed the recommended daily dose. This product is a nutritional supplement and should not replace a varied, balanced diet.

Keep out of childrens' reach.

As with any nutritional supplement, you should consult a health professional before taking this product if you are pregnant, breastfeeding or have a health problem.

Storage

Store away from direct light, heat and humidity.

See for yourself

Homotaurine 100 mg by SuperSmart label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Homotaurine 100 mg by SuperSmart

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Homotaurine

No known
interactions
100 mg per serving

Homotaurine (also called tramiprosate) is a small amino acid-like molecule studied mainly for slowing memory loss and Alzheimer's disease. Large clini...

Homotaurine monograph & interactions

Other (inactive) ingredients: Acacia Gum, White Rice Bran. These complete the product’s ingredient list but are not active constituents.

Interaction report

Homotaurine 100 mg by SuperSmart Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Homotaurine 100 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Homotaurine 100 mg, from the product label.

SuperSmart

See all SuperSmart products
Name
SN Worldwide Unipessoal, Lda
Street Address
Avenida Do Infante 66, Edificio Quinta Avenida 1 C
City
Funchal
ZipCode
9000-015
Pharmacist Counseling Corner

Homotaurine 100 mg by SuperSmart: Common Questions

Does Homotaurine 100 mg by SuperSmart interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Homotaurine 100 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Homotaurine 100 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is homotaurine used for?
Homotaurine has been studied for Alzheimer disease, cognitive impairment, glaucoma, and Parkinson disease. However, we don't have enough reliable evidence to say whether it actually works for any of these. Talk with your doctor about whether it's right for your situation.
What are the most common side effects?
In clinical trials, the most frequent side effects were nausea, vomiting, diarrhea, dizziness, headache, and sleep problems. Nausea and vomiting happened in 5% to 30% of people at higher doses, though interestingly, similar rates occurred in some placebo groups too.
Is it safe to take during pregnancy or while breastfeeding?
There isn't enough safety information, so the safety data advises against use in both pregnancy and breastfeeding. Talk with your doctor or pharmacist for personalized advice if you're in either situation.
How long has homotaurine been studied as a supplement?
While homotaurine has been used in clinical trials, long-term safety as a supplement is not well established. This is something to keep in mind if you're considering it for ongoing use.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Homotaurine 100 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Homotaurine 100 mg label
Go deeper

The Full Monographs Behind Homotaurine 100 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Homotaurine 100 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Homotaurine 15 references
  1. Aisen PS, Gauthier S, Vellas B, et al. Alzhemed: a potential treatment for Alzheimer's disease. Curr Alzheimer Res 2007;4:473-8.
  2. Greenberg SM, Rosand J, Schneider AT, et al. A phase 2 study of tramiprosate for cerebral amyloid angiopathy. Alzheimer Dis Assoc Disord 2006;20:269-74. PubMed
  3. Aisen PS, Saumier D, Briand R, et al. A Phase II study targeting amyloid-beta with 3APS in mild-to-moderate Alzheimer disease. Neurology 2006;67:1757-63.
  4. Wright TM. Tramiprosate. Drugs Today (Barc) 2006;42:291-8.
  5. Wong GT. FDA deems US Alzhemed trial results inconclusive. Alzheimer Research Forum. August 28, 2007. Available at: www.alzforum.org/new/detail.asp?id=1647. (Accessed 26 May 2009).
  6. McCaffrey P, Strobel G. Philadelphia: European trial of Alzhemed ends, marketing morphs to supplement. Alzheimer Research Forum. November 19, 2007. Available at: www.alzforum.org/new/detail.asp?id=1691. (Accessed 26 May 2009).
  7. Bossú P, Salani F, Ciaramella A, et al. Anti-inflammatory effects of homotaurine in patients with amnestic mild cognitive impairment. Front Aging Neurosci. 2018;10:285. PubMed
  8. Abushakra S, Porsteinsson A, Scheltens P, et al. Clinical effects of tramiprosate in APOE4/4 homozygous patients with mild Alzheimer's disease suggest disease modification potential. J Prev Alzheimers Dis. 2017;4(3):149-156. PubMed
  9. Spalletta G, Cravello L, Gianni W, et al. Homotaurine effects on hippocampal volume loss and episodic memory in amnestic mild cognitive impairment. J Alzheimers Dis. 2016;50(3):807-16. PubMed
  10. Ricciardi L, De Nigris F, Specchia A, Fasano A. Homotaurine in Parkinson's disease. Neurol Sci. 2015;36(9):1581-7. PubMed
  11. Gauthier S, Aisen PS, Ferris SH, et al. Effect of tramiprosate in patients with mild-to-moderate Alzheimer's disease: exploratory analyses of the MRI sub-group of the Alphase study. J Nutr Health Aging. 2009;13(6):550-7. PubMed
  12. Aisen PS, Gauthier S, Ferris SH, et al. Tramiprosate in mild-to-moderate Alzheimer's disease - a randomized, double-blind, placebo-controlled, multi-centre study (the Alphase Study). Arch Med Sci. 2011;7(1):102-11. PubMed
  13. Marino PF, Rossi GCM, Campagna G, et al. Effects of citicoline, homotaurine, and vitamin E on contrast sensitivity and visual-related quality of life in patients with primary open-angle glaucoma: A preliminary study. Molecules. 2020 Nov 29;25(23):5614. PubMed
  14. Toppi E, Sireno L, Lembo M, et al. IL-33 and IL-10 Serum Levels Increase in MCI Patients Following Homotaurine Treatment. Front Immunol 2022;13:813951. PubMed
  15. Rossi GCM, Rolle T, De Silvestri A, et al. Multicenter, Prospective, Randomized, Single Blind, Cross-Over Study on the Effect of a Fixed Combination of Citicoline 500 mg Plus Homotaurine 50 mg on Pattern Electroretinogram (PERG) in Patients With Open Angl

See these in context on the Homotaurine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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