Potassium Iodide 200 mcg Ingredients & Drug Interactions
by SuperSmart
What is this page for?
First and foremost: checking Potassium Iodide 200 mcg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Potassium Iodide 200 mcg is a dietary supplement by SuperSmart with 1 active ingredient. Its ingredients are commonly taken for preventing iodine deficiency, supporting thyroid hormone production, general energy and metabolism support.Based on those ingredients, 7 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Iodine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Potassium Iodide 200 mcg by SuperSmart
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HelloPharmacist Scorecard of Potassium Iodide 200 mcg by SuperSmart
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains a single active ingredient: iodine at 200 micrograms per tablet. Iodine is a mineral your body needs to make thyroid hormones and is important for metabolism and brain development.
The tablet also contains acacia gum as an inactive ingredient to bind and form the tablet.
Does it work?
Strong evidence
Iodine at this dose is likely effective for preventing or treating iodine deficiency and for protecting your thyroid after radiation exposure. The evidence suggests it may also be possibly effective for oral mucositis (mouth sores) and periodontitis (gum disease), though the data for those uses is less robust.
How safe is it?
Well-documented data
Iodine is generally well tolerated in normal dietary amounts, but high doses can cause thyroid problems—that's why taking this supplement requires appropriate medical guidance. The most common side effects from oral iodine are abdominal upset, diarrhea, headache, metallic taste, and nausea.
Rarely, some people can have a hypersensitivity reaction with symptoms like swelling, rash, or fever; chronic high-dose use has also been linked to acneform skin lesions. In pregnancy, adequate iodine matters for your baby's development, but you should take only the amount your doctor advises—avoid high-dose products on your own.
During breastfeeding, some iodine passes into milk, so follow your doctor's guidance to keep levels safe for your infant.
Meds to double-check
Moderate interaction found
Before taking this product, double-check your medications with your pharmacist if you take lithium, any antithyroid drugs, or amiodarone. All three interact with iodine at Moderate severity and require thyroid monitoring.
The bottom line
Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
Potassium iodide is useful if you have iodine deficiency or need thyroid protection after radiation, but it's not a casual supplement. If you take lithium, antithyroid drugs, or amiodarone, talk with your pharmacist before starting.
Pregnant and nursing mothers should use it only under medical direction.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 21, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Potassium Iodide 200 mcg, straight from the product label.
| Brand | SuperSmart |
|---|---|
| Barcode (UPC) | 5453003828181 |
| Net contents | 60 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | May 21, 2025 |
| DSLD ID | 332482 |
| Product type | Mineral |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Potassium Iodide 200 mcg by SuperSmart, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
Dietary Supplement
Formula
Potassium Iodide 200 mcg per day
Suggested/Recommended/Usage/Directions
Recommended use: Adults. Take one tablet a day.
Precautions
Precautions: Contains iodine. Do not exceed the recommended daily dose. This product is a nutritional supplement and should not be used to replace a varied, balanced diet.
Keep out of childrens' reach.
As with any nutritional supplement, you should consult a health professional before taking this product if you are pregnant, breastfeeding or have a health problem.
Storage
Store away from direct light, heat and humidity.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Potassium Iodide 200 mcg by SuperSmart label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Potassium Iodide 200 mcg by SuperSmart
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.
Iodine
Interacts with7 drugs
Iodine is an essential mineral your body needs to make thyroid hormones, and most people get enough from iodized salt, dairy, and seafood. Supplements...
Iodine monograph & interactionsOther (inactive) ingredients: Acacia Gum. These complete the product’s ingredient list but are not active constituents.
Potassium Iodide 200 mcg by SuperSmart Drug Interactions
HelloPharmacist Interaction Report
SuperSmart's Potassium Iodide 200 mcg contains iodine, which interacts with several medications you need to know about.
The most serious concern is lithium (used for bipolar disorder): combining iodine with lithium can add to lithium's effect on the thyroid, potentially lowering thyroid function. You'll want your thyroid checked if you're on both.
Read the full breakdown — every affected drug type, severity by severity
Iodine also interacts with antithyroid drugs (like propylthiouracil or methimazole) — it can alter how well they work, since iodine itself affects thyroid hormone production depending on your health history. If you take amiodarone (a heart rhythm medication), this supplement poses a similar risk: amiodarone is already iodine-rich, and adding more could push iodine levels too high and damage your thyroid.
All three of these interactions are Moderate in severity, which means thyroid monitoring matters.
Altogether, these interactions span 7 individual medications. Before you start this supplement, use the checker below to run your exact prescriptions against it — especially if you're on any thyroid or heart medication.
Check your own medications below · Editorial policy · How we use AI
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Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Potassium Iodide 200 mcg interact with 7 drugs. Click any drug to see the details.
1 of the 1 ingredient in Potassium Iodide 200 mcg interact with drugs. Each result below shows which ingredient is responsible. Iodine
AmiodaroneCordarone, Pacerone
How Amiodarone interacts with Potassium Iodide 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
IodineAmiodarone (cordarone) Moderate
Interaction Summary
Combining iodine with amiodarone might cause excessively high iodine levels.
Read the full Iodine + Amiodarone interactionCarbimazoleNeo-Mercazole
How Carbimazole interacts with Potassium Iodide 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
IodineAntithyroid Drugs Moderate
Interaction Summary
Iodine might alter the effects of antithyroid drugs.
Read the full Iodine + Carbimazole interactionLithium Carbonate (prescription Drug)Eskalith, Lithium Carbonate
How Lithium Carbonate (prescription Drug) interacts with Potassium Iodide 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
IodineLithium Moderate
Interaction Summary
Combining iodine with lithium might have additive hypothyroid effects.
Read the full Iodine + Lithium Carbonate (prescription Drug) interactionMethenamine MandelateMandelamine, Methimazole
How Methenamine Mandelate interacts with Potassium Iodide 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
IodineAntithyroid Drugs Moderate
Interaction Summary
Iodine might alter the effects of antithyroid drugs.
Read the full Iodine + Methenamine Mandelate interactionMethimazoleTapazole
How Methimazole interacts with Potassium Iodide 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
IodineAntithyroid Drugs Moderate
Interaction Summary
Iodine might alter the effects of antithyroid drugs.
Read the full Iodine + Methimazole interactionPotassium Iodide (prescription Drug)Thyro-Block
How Potassium Iodide (prescription Drug) interacts with Potassium Iodide 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
IodineAntithyroid Drugs Moderate
Interaction Summary
Iodine might alter the effects of antithyroid drugs.
Read the full Iodine + Potassium Iodide (prescription Drug) interactionPropylthiouracil, PtuPropylthiouracil
How Propylthiouracil, Ptu interacts with Potassium Iodide 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
IodineAntithyroid Drugs Moderate
Interaction Summary
Iodine might alter the effects of antithyroid drugs.
Read the full Iodine + Propylthiouracil, Ptu interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Potassium Iodide 200 mcg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Iodine
Amiodarone (Cordarone)
Combining iodine with amiodarone might cause excessively high iodine levels.
Amiodarone contains 37.3% iodine and can increase iodine levels. Concomitant use with iodine might increase the risk of having excessive iodine levels and adversely affecting thyroid function. Monitor thyroid function.
Antithyroid Drugs
Iodine might alter the effects of antithyroid drugs.
Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking iodine while using antithyroid drugs could alter the effects of the antithyroid drugs.
Lithium
Combining iodine with lithium might have additive hypothyroid effects.
Lithium can inhibit thyroid function. Several case reports suggest that concomitant use of lithium and potassium iodide can reduce thyroid function in otherwise healthy adults. Monitor thyroid function.
Brand information
Manufacturer and brand details for Potassium Iodide 200 mcg, from the product label.
SuperSmart
See all SuperSmart products- Name
- SN Worldwide Unipessoal, Lda
- Street Address
- Avenida Do Infante 66, Edificio Quinta Avenida 1 C
- City
- Funchal
- ZipCode
- 9000-015
Potassium Iodide 200 mcg by SuperSmart: Common Questions
Does Potassium Iodide 200 mcg by SuperSmart interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Who should actually take potassium iodide?
What are the most common side effects?
Can I take this while I'm pregnant?
Is iodine safe while breastfeeding?
Can I get iodine from food instead?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Potassium Iodide 200 mcg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Potassium Iodide 200 mcg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Potassium Iodide 200 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 26 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Iodine 26 references
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Goodman GA, Rall TW, Nies AS, Taylor P. The Pharmacological Basis of Therapeutics, 9th ed.
- Ghent WR, Eskin BA, Low DA, Hill LP. Iodine replacement in fibrocystic disease of the breast. Can J Surg 1993;36:453-60.
- Potassium iodide for nuclear exposure. Pharmacist's Letter/Prescriber's Letter 2001;17(12):171214.
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
- Cabezas C, Bustamante B, Holgado W, Begue RE. Treatment of cutaneous sporotrichosis with one daily dose of potassium iodide. Pediatr Infect Dis J 1996;15:352-4. PubMed
- Sterling JB, Heymann WR. Potassium iodide in dermatology: a 19th century drug for the 21st century-uses, pharmacology, adverse effects, and contraindications. J Am Acad Dermatol 2000;43:691-7. PubMed
- Yarrington CD, Pearce EN. Dietary iodine in pregnancy and postpartum. Clin Obstet Gynecol 2011;54:459-70. PubMed
- Goel, S., Mandhani, A., Srivastava, A., Kapoor, R., Gogoi, S., Kumar, A., and Bhandari, M. Is povidone iodine an alternative to silver nitrate for renal pelvic instillation sclerotherapy in chyluria? BJU.Int 2004;94(7):1082-1085. PubMed
- Teng, W., Shan, Z., Teng, X., Guan, H., Li, Y., Teng, D., Jin, Y., Yu, X., Fan, C., Chong, W., Yang, F., Dai, H., Yu, Y., Li, J., Chen, Y., Zhao, D., Shi, X., Hu, F., Mao, J., Gu, X., Yang, R., Tong, Y., Wang, W., Gao, T., and Li, C. Effect of iodine int
- Crawford, B. A., Cowell, C. T., Emder, P. J., Learoyd, D. L., Chua, E. L., Sinn, J., and Jack, M. M. Iodine toxicity from soy milk and seaweed ingestion is associated with serious thyroid dysfunction. Med J Aust. 10-4-2010;193(7):413-415. PubMed
- Ohkuma, M. Molluscum contagiosum treated with iodine solution and salicylic acid plaster. Int J Dermatol. 1990;29(6):443-445. PubMed
- Connelly KJ, Boston BA, Pearce EN, Sesser D, Snyder D, Braverman LE, Pino S, LaFranchi SH. Congenital hypothyroidism caused by excess prenatal maternal iodine ingestion. J Pediatr. 2012 Oct;161(4):760-2. PubMed
- Kasahara T, Narumi S, Okasora K, Takaya R, Tamai H, Hasegawa T. Delayed onset congenital hypothyroidism in a patient with DUOX2 mutations and maternal iodine excess. Am J Med Genet A. 2013 Jan;161A(1):214-7.
- Murcia M, Rebagliato M, Iñiguez C, Lopez-Espinosa MJ, Estarlich M, Plaza B, Barona-Vilar C, Espada M, Vioque J, Ballester F. Effect of iodine supplementation during pregnancy on infant neurodevelopment at 1 year of age. Am J Epidemiol. 2011 Apr 1;173(7):8 PubMed
- Sang Z, Wang PP, Yao Z, Shen J, Halfyard B, Tan L, Zhao N, Wu Y, Gao S, Tan J, Liu J, Chen Z, Zhang W. Exploration of the safe upper level of iodine intake in euthyroid Chinese adults: a randomized double-blind trial. Am J Clin Nutr. 2012 Feb;95(2):367-73 PubMed
- Speeckaert MM, Speeckaert R, Wierckx K, Delanghe JR, Kaufman JM. Value and pitfalls in iodine fortification and supplementation in the 21st century. Br J Nutr. 2011 Oct;106(7):964-73. PubMed
- Yun SE, Kang Y, Bae EJ, Hwang K, Jang HN, Cho HS, Chang SH, Park DJ. Iodine-induced thyrotoxic hypokalemic paralysis after ingestion of Salicornia herbace. Ren Fail. 2014 Apr;36(3):461-3.
- Iodine Hypersensitivity. Pharmacist's Letter/Prescriber's Letter 2011; 27(5):270504.
- Hammel JA, Selby JC. Pustular eruption in a patient with cancer treated with complementary and alternative medicine. JAMA Dermatology 2017 October; E1. doi: 10.1001/jamadermatol.2017.3749. [Epub ahead of print] PubMed
- Gil GS, Smith BW, Guerra JR, Williams WT. Acute Delirium in a Hypothyroid Patient Precipitated by Iodine Supplements Use. Am J Ther. 2018;25(6):e717-e718. PubMed
- Hamby T, Kunnel N, Dallas JS, Wilson DP. Maternal iodine excess: an uncommon cause of acquired neonatal hypothyroidism. J Pediatr Endocrinol Metab. 2018;31(9):1061-1064. PubMed
- Censi S, Watutantrige-Fernando S, Groccia G, et al. The Effects of Iodine Supplementation in Pregnancy on Iodine Status, Thyroglobulin Levels and Thyroid Function Parameters: Results from a Randomized Controlled Clinical Trial in a Mild-to-Moderate Iodine
- Rovner MS, Wolf BJ, Rubin M, et al. Instillation of 5% Povidone-Iodine Ophthalmic Drops Decreases the Respiratory Rate in Children Undergoing Strabismus Surgery: A Randomized Controlled Trial. J Pediatr Ophthalmol Strabismus. 2019;56(6):378-382. PubMed
- Guenezan J, Garcia M, Strasters D, et al. Povidone Iodine Mouthwash, Gargle, and Nasal Spray to Reduce Nasopharyngeal Viral Load in Patients With COVID-19: A Randomized Clinical Trial. JAMA Otolaryngol Head Neck Surg. 2021;147(4):400-401. PubMed
- Li F, Wan S, Zhang L, et al. A Meta-Analysis of the Effect of Iodine Excess on the Intellectual Development of Children in Areas with High Iodine Levels in their Drinking Water. Biol Trace Elem Res 2022;200(4):1580-1590. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC