Hyaluronic Acid Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Hyaluronic Acid against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Hyaluronic Acid is a dietary supplement by Pure Encapsulations with 1 active ingredient. Its ingredients are commonly taken for skin hydration and aging, joint comfort and osteoarthritis, dry eyes.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Hyaluronic Acid by Pure Encapsulations
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: hyaluronic acid. It's a naturally occurring substance found in your body that helps hold water in tissues—commonly used in skincare and eye care products.
The capsule is made from vegetarian material, and the only other ingredient listed is hypoallergenic plant fiber, which is an inactive filler.
Does it work?
Moderate evidence
Hyaluronic acid is possibly effective for dry eye and venous leg ulcers (slow-healing sores on the leg). For aging skin, allergic rhinitis (hay fever), and sexual dysfunction, the evidence we hold is insufficient to rate it—meaning studies haven't established whether it works for those purposes.
If you're considering it for one of those first two uses, talk with your doctor about whether it fits your situation.
How safe is it?
Well-documented data
Taken by mouth and applied to skin, hyaluronic acid is generally well tolerated in most adults. However, the safety notes on file caution that long-term safety of supplements isn't fully studied, and they advise against oral supplements unless your doctor recommends otherwise.
When used topically, it's occasionally reported to cause eczema, redness, itching, or (rarely) wound problems. Eye drops containing hyaluronic acid have rarely caused eye pain.
Meds to double-check
No known interactions
No interactions are documented in our data for the hyaluronic acid in this product. That said, documented interactions don't mean others don't exist—they just haven't been identified yet.
Clear it with your doctor or pharmacist before taking it alongside any prescription medication.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.
Hyaluronic Acid by Pure Encapsulations may help with dry eyes or certain leg wounds if taken by mouth, though evidence is limited. Since safety data for long-term oral use isn't complete and the product carries a caution to avoid it unless advised by your doctor, it's worth discussing with your healthcare provider before you start—especially if you take any medications or have an existing health condition.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 7, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Hyaluronic Acid, straight from the product label.
| Brand | Pure Encapsulations |
|---|---|
| Barcode (UPC) | 766298006055 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jan 7, 2019 |
| DSLD ID | 184522 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Hyaluronic Acid by Pure Encapsulations, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Hyaluronic Acid | 70 mg | -- |
Other ingredients: hypoallergenic Plant Fiber, Vegetarian Capsule
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage
Store in a cool, dry place.
Suggested/Recommended/Usage/Directions
Recommendations: As a dietary supplement, take 1 capsule, 1-2 times daily, with or between meals, or as directed by a health professional.
Precautions
Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.
Keep out of the reach of children.
Use only if safety seal is intact.
General Statements
Scan to learn about our hypoallergenic supplements
Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.
Supports skin hydration, joint lubrication and comfort
Formulation
Certified Gluten-Free by the Gluten-Free Certification Organization, www.gluten.org
Gluten-free, Non-GMO & Hypoallergenic
Gluten-free, Non-GMO & Hypoallergenic
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
GF
Brand IP Statement(s)
HyaMax is a U.S.A. registered trademark of Fenchem.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
General
v5 code: HYA6
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Hyaluronic Acid by Pure Encapsulations label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Hyaluronic Acid by Pure Encapsulations
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Hyaluronic Acid
No knowninteractions
Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin...
Hyaluronic Acid monograph & interactionsOther (inactive) ingredients: Hypoallergenic Plant Fiber, Vegetarian Capsule. These complete the product’s ingredient list but are not active constituents.
Hyaluronic Acid by Pure Encapsulations Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Hyaluronic Acid. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Hyaluronic Acid, from the product label.
Pure Encapsulations
See all Pure Encapsulations products- Name
- Pure Encapsulations
- Street Address
- 490 Boston Post Road
- City
- Sudbury
- State
- MA
- Phone Number
- 1-800-753-2277
- Web Address
- www.PureEncapsulations.com
Hyaluronic Acid by Pure Encapsulations: Common Questions
Does Hyaluronic Acid by Pure Encapsulations interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is hyaluronic acid safe to take by mouth long-term?
Can hyaluronic acid help my dry eyes?
What are the most common side effects?
Is it safe during pregnancy or breastfeeding?
Does this product contain any fillers?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Hyaluronic Acid is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Hyaluronic Acid’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Hyaluronic Acid's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Hyaluronic Acid 4 references
- Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
- U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
- Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
- Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC